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嚢胞性線維症の2030年までの市場予測:薬剤クラス別、治療法別、投与経路別、流通チャネル別、地域別の世界分析Cystic Fibrosis Market Forecasts to 2030 - Global Analysis By Drug Class, Treatment Method, Route of Administration, Distribution Channel and By Geography |
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嚢胞性線維症の2030年までの市場予測:薬剤クラス別、治療法別、投与経路別、流通チャネル別、地域別の世界分析 |
出版日: 2023年11月01日
発行: Stratistics Market Research Consulting
ページ情報: 英文 200+ Pages
納期: 2~3営業日
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Stratistics MRCによると、嚢胞性線維症の世界市場は2023年に114億9,000万米ドルを占め、予測期間中にCAGR 22.4%で成長し、2030年には473億米ドルに達すると予測されています。
嚢胞性線維症(CF)として知られる遺伝性疾患の原因は遺伝子変異です。特定の体液のタンパク質分泌は遺伝子によって制御されています。これは体内の様々な器官に影響を及ぼし、粘液や汗を濃くする傾向があります。さらに、この病気は電解質輸送系を変化させ、細胞によるナトリウムと水分の吸収をもたらし、汗と粘液の分泌を担当する腺に問題を引き起こします。
嚢胞性線維症患者登録によると、米国では現在3万人以上がこの病気に苦しんでおり、世界中で約7万人がこの病気に苦しんでいると推定されています。
個々の患者のCFTR遺伝子変異を正確に特定する能力は、遺伝子配列決定技術と遺伝子検査の進歩によって可能となっています。この個別化アプローチの助けにより、医療専門家は、各患者の特定の遺伝子プロファイルに応じて治療計画をカスタマイズし、最適な薬剤を提供することができます。さらに、個別化医療を重視することで、患者の満足度と治療効果を高めることができるため、市場はさらに活性化しています。
嚢胞性線維症の治療費は非常に高額で、特にCFTRモジュレーターの場合、年間数十万米ドルに上ることもあります。このような過大な出費は、保険会社や医療システムを圧迫し、すべての患者にアクセスを提供することを困難にする可能性があります。さらに、これらの治療薬の長期的な購入可能性に関する懸念も、費用によってもたらされ、市場拡大に影響を及ぼす可能性があります。
インテリジェント吸入器や効果的なネブライザーなど、ドラッグデリバリーの進歩により、治療管理は向上しています。しかし、これらの実用的かつ効率的なドラッグデリバリー戦略は、患者が治療の恩恵を十分に受けられることを保証するため、患者の経験を向上させ、アドヒアランスを促進し、ひいては市場拡大の一助となります。
嚢胞性線維症の治療計画には、薬剤、治療法、生活習慣の改善が複雑に絡み合っていることがよくあります。この複雑さは患者を圧倒し、治療へのアドヒアランスを低下させる可能性があります。さらに、コンプライアンス違反の結果、医療費用が増加し、増悪が頻発する可能性があります。
COVID-19の大流行は、患者の治療、臨床試験、医療システムに大きな混乱を引き起こし、嚢胞性線維症市場にも影響を与えました。パンデミックは医療資源に負担をかけ、新しい治療法の導入を遅らせ、研究開発を先送りしました。嚢胞性線維症と診断された人々は、ハイリスク集団とみなされ、健康上のリスクが増大し、必要な医療へのアクセスが制限されることも多かっています。さらに、パンデミックの経済的影響は、医療システムと患者の経済的負担を増大させ、嚢胞性線維症治療の費用と利用しやすさに影響を与える可能性があっています。
膜貫通伝導調節因子モジュレーターは、この複雑で課題も多い遺伝性疾患の治療にパラダイムシフトをもたらすと期待されており、その変革的インパクトから嚢胞性線維症市場で最大のシェアを占めると予想されています。さらに、嚢胞性線維症の治療は、Trikaftaのような膜貫通伝導調節因子モジュレーターによって一変しました。これらの薬剤は、嚢胞性線維症の原因となる根本的な遺伝子欠損に対処することにより、粘液クリアランスと塩化物輸送を改善します。特定の遺伝子変異を持つ多くの患者にとって、膜貫通伝導調節因子モジュレーターは肺機能を大幅に改善し、増悪を抑え、QOLを向上させる。
嚢胞性線維症市場では、吸入療法分野が最もCAGRが高いです。吸入療法は、標的を絞った効果的な方法で薬剤を肺に直接投与するため、近年ますます普及しています。吸入器は、嚢胞性線維症の症状のコントロールを補助する薬剤を送達するために、これらの治療で一般的に使用されています。さらに、吸入セグメントの著しい成長は、吸入技術の進歩、吸入治療の利点に関する意識の高まり、特に吸入投与を目的とした新規薬剤の創出など、様々な要因に起因しています。
嚢胞性線維症は北米が最大の市場シェアを占めています。これは、同地域の市場優位性を支えるいくつかの要因によるものです。まず、北米では一般市民も医療関係者も嚢胞性線維症に対する認識が高く、医療のインフラが整備されています。そのため、患者の早期診断・治療が容易で、患者層が拡大し、嚢胞性線維症治療薬市場が拡大します。さらに、この地域には、最先端の嚢胞性線維症治療法の開発に積極的に取り組んでいる製薬会社や研究施設が数多くあります。最先端の医療機器が利用可能であることや、有利な診療報酬制度も、この地域の市場シェアを押し上げています。
アジア太平洋は、嚢胞性線維症市場において最も高いCAGRが見込まれています。この地域では嚢胞性線維症の患者数が増加しており、医療を含む多くの産業で急成長が見られます。この地域の急成長は、嚢胞性線維症に対する社会的認知の拡大、医療インフラの充実、医療費の上昇など、多くの要因によるものです。さらに、中国やインドなどの各国政府は、医療の低価格化と利用しやすさの向上を目指したプログラムを実施しており、診断と治療により良い選択肢を提供することで、嚢胞性線維症患者に恩恵をもたらすでしょう。
According to Stratistics MRC, the Global Cystic Fibrosis Market is accounted for $11.49 billion in 2023 and is expected to reach $47.30 billion by 2030 growing at a CAGR of 22.4% during the forecast period. A genetic mutation is the cause of the inherited disease known as cystic fibrosis (CF). Certain bodily liquids' protein secretion is regulated by genes. This affects different organs in the body, which tends to thicken mucus and sweat. Moreover, this illness modifies the electrolyte transport system, which results in the absorption of sodium and water by cells and causes issues with the glands responsible for producing sweat and mucus.
According to the Cystic Fibrosis Patient Registry, it is estimated that more than 30,000 people are currently suffering from this condition in the U.S. and it is estimated that about 70,000 people are suffering from it across the globe.
The ability to precisely identify CFTR gene mutations in individual patients has been made possible by advances in genetic sequencing technologies and genetic testing. With the help of this individualized approach, medical professionals can customize treatment plans and offer the best medications depending on each patient's particular genetic profile. Additionally, the market is further propelled by the emphasis on personalized medicine, which raises patient satisfaction and treatment effectiveness.
The cost of treating cystic fibrosis can be extremely high, sometimes amounting to hundreds of thousands of dollars per year, particularly for CFTR modulators. These excessive expenses may put pressure on insurers and healthcare systems, making it more difficult to provide access to all patients. Furthermore, concerns about these treatments' long-term affordability are also brought up by cost, which could have an impact on market expansion.
Treatment administration has been enhanced by advances in drug delivery, such as intelligent inhalers and effective nebulizers. However, since they guarantee that patients get the full benefit of their treatments, these practical and efficient drug delivery strategies improve patient experience, promote adherence, and subsequently aid in market expansion.
Treatment plans for cystic fibrosis frequently entail a complicated mix of drugs, therapies, and lifestyle modifications. This complexity has the potential to overwhelm patients and result in poor adherence to treatment, which will ultimately compromise the efficacy of therapies and patient outcomes. Moreover, healthcare expenses may rise, and exacerbations may occur more frequently as a result of noncompliance.
The COVID-19 pandemic caused major disruptions in patient care, clinical trials, and healthcare systems, which in turn affected the cystic fibrosis market. The pandemic put a strain on healthcare resources, delayed the introduction of new treatments, and postponed research and development. Individuals diagnosed with cystic fibrosis, who were regarded as a high-risk population, experienced increased health risks and frequently had limited access to necessary medical care. Furthermore, the pandemic's economic effects put more strain on healthcare systems and patients' finances, which might have an impact on the cost and accessibility of cystic fibrosis treatments.
CFTR modulators are expected to hold the largest share in the cystic fibrosis market due to their transformative impact, which is expected to represent a paradigm shift in the treatment of this complex and challenging genetic disease. Moreover, treatment for cystic fibrosis has been transformed by CFTR modulators such as Trikafta. These medications improve mucus clearance and chloride transport by addressing the underlying genetic defect that causes cystic fibrosis. For many patients with particular genetic mutations, CFTR modulators greatly improve lung function, lower exacerbations, and improve quality of life.
The inhaled segment of the cystic fibrosis market has the highest CAGR. Because inhaled therapies deliver medication directly to the lungs in a targeted and effective manner, they have become increasingly popular in recent years. Inhalers are commonly used in these therapies to deliver medications that assist in controlling the symptoms of cystic fibrosis. Additionally, the significant growth of the inhaled segment can be attributed to various factors, such as the progression of inhalation technology, heightened consciousness regarding the advantages of inhalation treatments, and the creation of novel medications especially intended for inhalation administration.
North America holds the largest market share for cystic fibrosis. This is explained by a number of factors that support the region's market dominance. First off, both the general public and medical professionals in North America are highly aware of cystic fibrosis, and the continent has a well-established healthcare infrastructure. This makes it easier to diagnose and treat patients early, which expands the patient pool and raises the market for cystic fibrosis treatments. Furthermore, there are many pharmaceutical companies and research facilities in the area that are actively working to develop cutting-edge cystic fibrosis treatments. The availability of cutting-edge medical equipment and advantageous reimbursement practices also boost the market share of the area.
The Asia-Pacific region is anticipated to have the highest CAGR in the cystic fibrosis market. This region is seeing a rise in the number of cases of cystic fibrosis and is seeing rapid growth in a number of industries, including healthcare. The region's rapid growth is attributed to a number of factors, including expanding public awareness of cystic fibrosis, enhancing healthcare infrastructure, and rising healthcare costs. Moreover, governments in nations such as China and India are implementing programs aimed at improving healthcare affordability and accessibility, which will benefit patients with cystic fibrosis by providing better options for diagnosis and treatment.
Some of the key players in Cystic Fibrosis market include: Pharmaxis Ltd , Gilead Sciences, Inc., Teva Pharmaceuticals, Genentech Inc , AbbVie Inc., Mylan N.V, Viatris Inc., Novartis AG, Allergan PLC, Pfizer Inc, Nestle Health Science, Hoffmann-La Roche AG , BayerAG, Vertex Pharmaceuticals Incorporated, AstraZeneca , Chiesi Farmaceutici SpA and Horizon Therapeutic Plc.
In October 2023, Teva Pharmaceuticals and Sanofi have announced an agreement to jointly develop and commercialise a treatment for inflammatory bowel disease, with the deal potentially worth up to $1.5bn.The candidate, Teva's TEV'574, is an anti-TL1A therapy currently being evaluated in phase 2b clinical trials as a treatment for ulcerative colitis and Crohn's disease, the two main types of inflammatory bowel disease.
In October 2023, Viatris Inc., a global healthcare company, today announced it has received an offer for the divestiture of substantially all of its Over-the-Counter (OTC) business, and has entered into definitive agreements to divest its Women's Healthcare business, its Active Pharmaceutical Ingredients (API) business in India and commercialization rights in certain non-core markets that were acquired as part of the Upjohn Transaction.
In September 2023, PeptiDream Inc., a public Kanagawa, Japan-based biopharmaceutical today announced a new multi-target collaboration and license agreement with U.S.-based Genentech, a member of the Roche Group, focused on the discovery and development of novel macrocyclic peptide-radioisotope ("peptide-RI") drug conjugates.