オリゴヌクレオチド合成の市場規模、シェア、成長分析：製品別、タイプ別、用途別、エンドユーザー別、地域別 - 産業予測 2025～2032年

オリゴヌクレオチド合成市場規模は2023年に78億米ドルと評価され、2024年の92億1,000万米ドルから2032年には348億6,000万米ドルに成長し、予測期間（2025-2032年）のCAGRは18.1%で成長する見通しです。

オリゴヌクレオチド合成の世界需要は、慢性疾患の罹患率の上昇と医療研究開発への多額の投資により、大きく成長する見通しです。精密医療や個別化医療へのシフトが進むとともに、遺伝子治療が受け入れられつつあり、オリゴヌクレオチド合成プロバイダーに新たな道が開かれることが期待されます。さらに、合成技術の進歩や核酸ベースの治療薬の幅広い応用により、市場機会はさらに拡大すると思われます。旺盛なヘルスケア研究費に支えられた北米が市場をリードすると予測されています。しかし、高い合成コスト、複雑な規制状況、遺伝子治療を取り巻く倫理的配慮、限られた製造能力などの課題が、この発展途上の環境における成長を阻害する可能性があります。

目次

イントロダクション

• 調査の目的
• 調査範囲
• 定義

調査手法

• 情報調達
• 二次と一次データの方法
• 市場規模予測
• 市場の前提条件と制限

エグゼクティブサマリー

• 世界市場の見通し
• 供給と需要の動向分析
• セグメント別機会分析

市場力学と見通し

• 市場概要
• 市場規模
• 市場力学
  • 促進要因と機会
  • 抑制要因と課題
• ポーターの分析

主な市場の考察

• 重要成功要因
• 競合の程度
• 主な投資機会
• 市場エコシステム
• 市場の魅力指数（2024年）
• PESTEL分析
• マクロ経済指標
• バリューチェーン分析
• 価格分析
• 規制分析

オリゴヌクレオチド合成市場規模：製品別& CAGR（2025-2032）

• 市場概要
• オリゴヌクレオチド
  • DNA
  • 列ベース
  • 配列ベース
  • RNA
  • テクノロジー
  • 列ベース
  • 配列ベース
  • タイプ
  • 短いRNAオリゴ（<65 nt）
  • 長いRNAオリゴ（>65 nt）
  • CRISPR（sgRNA）
• 試薬
• 装置

オリゴヌクレオチド合成市場規模：タイプ別& CAGR（2025-2032）

• 市場概要
• カスタムオリゴ
• プレデザインオリゴ

オリゴヌクレオチド合成市場規模：用途別& CAGR（2025-2032）

• 市場概要
• 治療への応用
• 診断
• 調査
• その他

オリゴヌクレオチド合成市場規模：エンドユーザー別& CAGR（2025-2032）

• 市場概要
• 学術調査機関
• 製薬・バイオテクノロジー企業
• 診断検査室
• その他

オリゴヌクレオチド合成市場規模：地域別& CAGR（2025-2032）

• 北米
  • 米国
  • カナダ
• 欧州
  • ドイツ
  • スペイン
  • フランス
  • 英国
  • イタリア
  • その他欧州地域
• アジア太平洋地域
  • 中国
  • インド
  • 日本
  • 韓国
  • その他アジア太平洋地域
• ラテンアメリカ
  • ブラジル
  • その他ラテンアメリカ地域
• 中東・アフリカ
  • GCC諸国
  • 南アフリカ
  • その他中東・アフリカ

競合情報

• 上位5社の比較
• 主要企業の市場ポジショニング（2024年）
• 主な市場企業が採用した戦略
• 最近の市場動向
• 企業の市場シェア分析（2024年）
• 主要企業の企業プロファイル
  • 企業の詳細
  • 製品ポートフォリオ分析
  • 企業のセグメント別シェア分析
  • 収益の前年比比較（2022-2024）

主要企業プロファイル

• Thermo Fisher Scientific（USA）
• Merck KGaA（Germany）
• Agilent Technologies（USA）
• LGC Biosearch Technologies（UK）
• Integrated DNA Technologies（IDT）（USA）
• Eurofins Genomics（Luxembourg）
• GenScript Biotech Corporation（USA）
• Twist Bioscience（USA）
• Bio-Synthesis Inc.（USA）
• ATUM（USA）
• DNA Script（France）
• SGI-DNA（USA）
• Eurogentec（Kaneka）（Belgium）
• Creative Biogene（USA）
• GeneCust Europe（Luxembourg）
• Synbio Technologies（USA）
• Epoch Life Science, Inc.（USA）
• Bioneer Corporation（South Korea）
• Genewiz（Azenta Life Sciences）（USA）

結論と提言

Oligonucleotide Synthesis Market size was valued at USD 7.8 billion in 2023 and is poised to grow from USD 9.21 billion in 2024 to USD 34.86 billion by 2032, growing at a CAGR of 18.1% during the forecast period (2025-2032).

The global demand for oligonucleotide synthesis is poised for significant growth, driven by the rising incidence of chronic diseases and substantial investments in medical research and development. The increasing shift towards precision and personalized medicine, alongside the growing acceptance of gene therapies, is expected to open new avenues for oligonucleotide synthesis providers. Additionally, advancements in synthesis technologies and the broader application of nucleic acid-based therapeutics will further enhance market opportunities. North America, supported by robust healthcare research spending, is projected to lead the market. However, challenges such as high synthesis costs, complex regulatory environments, ethical considerations surrounding gene therapies, and limited manufacturing capabilities could impede growth in this evolving landscape.

Top-down and bottom-up approaches were used to estimate and validate the size of the Oligonucleotide Synthesis market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Oligonucleotide Synthesis Market Segments Analysis

Global Oligonucleotide Synthesis Market is segmented by Product, Type, Application, End User and region. Based on Product, the market is segmented into Oligonucleotide, Reagents and Equipment. Based on Type, the market is segmented into Custom Oligos and Predesigned Oligos. Based on Application, the market is segmented into Therapeutic Applications, Diagnostics, Research and Others. Based on End User, the market is segmented into Academic Research Institutes, Pharmaceutical and Biotechnology Companies,, Diagnostic Laboratories and Others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Driver of the Oligonucleotide Synthesis Market

The oligonucleotide synthesis market is primarily driven by the pivotal role oligonucleotides play in essential diagnostic techniques, including PCR, qPCR, and next-generation sequencing (NGS). As the demand for early diagnostic solutions rises swiftly, this trend is expected to pave the way for significant growth opportunities within the oligonucleotide synthesis sector in the future. The increasing reliance on these nucleic acid sequences in various biomedical applications highlights their importance, thereby reinforcing the market's potential to expand in response to innovations and advancements in diagnostic methodologies and technologies.

Restraints in the Oligonucleotide Synthesis Market

The oligonucleotide synthesis market faces significant constraints due to high costs associated with the production of high-purity or complex oligonucleotides, particularly those needed for therapeutic purposes. The expenses linked to purification processes and quality control measures exacerbate this financial challenge, making it difficult for smaller biotech companies to access these essential resources. As a result, the high operational costs restrict the ability of these firms to engage in oligonucleotide synthesis, ultimately hindering innovation and development within the industry. This economic barrier can limit competition and slow down advancements in therapeutic solutions reliant on oligonucleotides.

Market Trends of the Oligonucleotide Synthesis Market

The oligonucleotide synthesis market is witnessing a dynamic trend towards the integration of artificial intelligence (AI) and automation, significantly enhancing the efficiency, accuracy, and scalability of synthesis processes. These advancements are not only streamlining operational workflows but are also reducing costs, making oligonucleotide synthesis more accessible to researchers and biotech companies. Automated synthesizers combined with AI-driven design tools are increasingly popular, enabling rapid customization and development of oligonucleotides for various applications, including gene therapy and diagnostics. This technological shift is poised to transform the landscape of the oligonucleotide synthesis market, driving growth and innovation well into the future.

Table of Contents

Introduction

• Objectives of the Study
• Scope of the Report
• Definitions

Research Methodology

• Information Procurement
• Secondary & Primary Data Methods
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Global Market Outlook
• Supply & Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Overview
• Market Size
• Market Dynamics
  • Drivers & Opportunities
  • Restraints & Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of substitute
  • Bargaining power of buyers
  • Threat of new entrants
  • Bargaining power of suppliers

Key Market Insights

• Key Success Factors
• Degree of Competition
• Top Investment Pockets
• Market Ecosystem
• Market Attractiveness Index, 2024
• PESTEL Analysis
• Macro-Economic Indicators
• Value Chain Analysis
• Pricing Analysis
• Regulatory Analysis

Global Oligonucleotide Synthesis Market Size by Product & CAGR (2025-2032)

• Market Overview
• Oligonucleotide
  • DNA
  • Column-based
  • Array-based
  • RNA
  • Technology
  • Column-based
  • Array-based
  • Type
  • Short RNA Oligos (<65 nt)
  • Long RNA Oligos (>65 nt)
  • CRISPR (sgRNA)
• Reagents
• Equipment

Global Oligonucleotide Synthesis Market Size by Type & CAGR (2025-2032)

• Market Overview
• Custom Oligos
• Predesigned Oligos

Global Oligonucleotide Synthesis Market Size by Application & CAGR (2025-2032)

• Market Overview
• Therapeutic Applications
• Diagnostics
• Research
• Others

Global Oligonucleotide Synthesis Market Size by End User & CAGR (2025-2032)

• Market Overview
• Academic Research Institutes
• Pharmaceutical and Biotechnology Companies,
• Diagnostic Laboratories
• Others

Global Oligonucleotide Synthesis Market Size & CAGR (2025-2032)

• North America (Product, Type, Application, End User)
  • US
  • Canada
• Europe (Product, Type, Application, End User)
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific (Product, Type, Application, End User)
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America (Product, Type, Application, End User)
  • Brazil
  • Rest of Latin America
• Middle East & Africa (Product, Type, Application, End User)
  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Competitive Intelligence

• Top 5 Player Comparison
• Market Positioning of Key Players, 2024
• Strategies Adopted by Key Market Players
• Recent Developments in the Market
• Company Market Share Analysis, 2024
• Company Profiles of All Key Players
  • Company Details
  • Product Portfolio Analysis
  • Company's Segmental Share Analysis
  • Revenue Y-O-Y Comparison (2022-2024)

Key Company Profiles

• Thermo Fisher Scientific (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Agilent Technologies (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• LGC Biosearch Technologies (UK)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Integrated DNA Technologies (IDT) (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Eurofins Genomics (Luxembourg)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• GenScript Biotech Corporation (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Twist Bioscience (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio-Synthesis Inc. (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• ATUM (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• DNA Script (France)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• SGI-DNA (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Eurogentec (Kaneka) (Belgium)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Creative Biogene (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• GeneCust Europe (Luxembourg)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Synbio Technologies (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Epoch Life Science, Inc. (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bioneer Corporation (South Korea)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Genewiz (Azenta Life Sciences) (USA)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments

Conclusion & Recommendations