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市場調査レポート
商品コード
1540908
オリゴヌクレオチド合成市場レポート：製品、用途、最終用途、地域別、2024～2032年Oligonucleotide Synthesis Market Report by Product, Application (PCR Primers, PCR Assays and Panels, Sequencing, DNA Microarrays, Fluorescence In-Situ Hybridization, Antisense Oligonucleotides, and Others), End Use, and Region 2024-2032 |
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| オリゴヌクレオチド合成市場レポート：製品、用途、最終用途、地域別、2024～2032年 |
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出版日: 2024年08月10日
発行: IMARC
ページ情報: 英文 147 Pages
納期: 2～3営業日
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- 全表示
- 概要
- 図表
- 目次
世界のオリゴヌクレオチド合成市場規模は2023年に30億米ドルに達しました。今後、IMARC Groupは、市場は2032年までに80億米ドルに達し、2024～2032年の間に11.1％の成長率（CAGR）を示すと予測しています。大衆の間で遺伝性疾患の有病率が高まっていること、新規治療戦略の開拓、低分子干渉RNA（siRNA）やアンチセンスオリゴヌクレオチドを用いた治療法の普及が、市場を推進している主要要因の一部です。
オリゴヌクレオチド合成は、オリゴヌクレオチドと呼ばれる短いDNAまたはRNA分子を、あらかじめ決められた配列で構築するプロセスを指します。オリゴヌクレオチドの長さは数塩基から200塩基程度まです。このプロセスは、制御された実験室環境で化学的に達成され、通常は固相ホスホルアミダイト化学を用います。この方法では、ヌクレオチドは成長する鎖に順次付加され、それぞれの付加は一連の化学反応を伴います。この技術により、科学者は遺伝子合成、ポリメラーゼ連鎖反応（PCR）、CRISPR-Cas9のような遺伝子編集ツール、分子診断試験など、様々な用途のカスタムメイドのオリゴヌクレオチドを生成することができます。オリゴヌクレオチド合成の進歩は、ゲノミクスと分子生物学の研究を劇的に加速し、医療・生物学研究における多くのブレークスルーを支えてきました。
大衆の間で遺伝性疾患の有病率が上昇していることが、世界市場を大きく牽引しています。このため、オリゴヌクレオチド別の治療法が重要な役割を果たす、新しい治療戦略の開発が必要とされています。例えば、低分子干渉RNA（siRNA）やアンチセンス・オリゴヌクレオチドを用いた治療法は、デュシェンヌ型筋ジストロフィーや脊髄性筋萎縮症などの遺伝性疾患の治療において研究・利用されています。このように、遺伝性疾患の有病率の増加が世界レベルでの需要を牽引しています。これとともに、バイオインフォマティクスとデータサイエンスの成長がオリゴヌクレオチド合成産業に直接的な影響を与えています。大規模なゲノムデータセットの解析能力の向上も市場にプラスの影響を与えています。したがって、計算能力の向上は、新規オリゴヌクレオチドの合成需要の増加を促進しています。さらに、オリゴヌクレオチド、特にアンチセンスオリゴヌクレオチドは、エピジェネティクスの研究や治療において効果的なツールであることが示されており、遺伝子発現を調節するのに役立っています。
オリゴヌクレオチド合成市場傾向/促進要因：
医療と製薬業界における需要の高まり
個別化医療や治療に対する世界の需要は急速に高まっており、オリゴヌクレオチド合成市場の前例のない拡大につながっています。これらの合成された配列は、がんを含む様々な遺伝子疾患や疾病に対する標的治療法の開発に不可欠な要素です。これに伴い、アンチセンスオリゴヌクレオチド、アプタマー、siRNA、免疫刺激性オリゴヌクレオチドなどの治療用オリゴヌクレオチドの進歩は、遺伝子発現を特異的に阻害または変化させることにより、疾患治療に革命をもたらしています。さらに、カスタム・オリゴヌクレオチドの合成は、mRNAベースのCOVID-19ワクチンを含むワクチン製造の基本であり、これらは有効性が証明され、現在広く使用されています。製薬会社や研究者が、病気の治療や予防におけるオリゴヌクレオチドの新規用途を発見し続けているため、オリゴヌクレオチド合成の需要は増加の一途をたどっています。
技術の進歩と革新
オリゴヌクレオチド合成技術の着実な開拓と改良が市場成長の原動力となっています。さらに、高性能合成システムや自動合成システムなど、合成プロセスにおける技術革新が、オリゴヌクレオチド生産の効率、精度、拡大性を高めています。さらに、DNA配列決定や遺伝子編集（CRISPR-Cas9など）を含むバイオインフォマティクスや合成生物学の発展は、オリゴヌクレオチドを正確に合成する能力に大きく依存しています。これらの進歩は、より複雑で多様性のあるカスタム配列の作成を可能にし、合成生物学における迅速なプロトタイプ試験を促進することで、より効率的な研究開発を促進します。このような継続的な技術の進歩や開発も市場に貢献しています。
共同研究やパートナーシップの拡大
製薬会社、バイオテクノロジー企業、研究機関の共同研究やパートナーシップは、遺伝性疾患に対するオリゴヌクレオチド療法の開発と商業化を進める上で不可欠な推進力となっています。このような協力関係は、多様な専門知識、リソース、資金を結集し、科学的発見を実用的で効果的な治療法へと加速する相乗的な環境を作り出しています。医薬品開発、臨床試験、規制プロセスにおける経験を持つ製薬会社は、共同研究に不可欠な専門知識を記載しています。製薬会社は、医薬品開発の複雑な情勢を乗り切り、オリゴヌクレオチド治療が安全性と有効性に関する規制基準を満たしていることを確認するために必要なインフラ、知識、資源を持っています。彼らの関与は、既存のネットワーク、製造能力、流通チャネルを活用することで、商業化への道のりを合理化するのに役立ちます。
目次
第1章 序文
第2章 調査範囲と調査手法
- 調査の目的
- ステークホルダー
- データソース
- 一次情報
- 二次情報
- 市場推定
- ボトムアップアプローチ
- トップダウンアプローチ
- 調査手法
第3章 エグゼクティブサマリー
第4章 イントロダクション
- 概要
- 主要業界動向
第5章 世界のオリゴヌクレオチド合成市場
- 市場概要
- 市場実績
- COVID-19の影響
- 市場予測
第6章 市場内訳：製品別
- 合成オリゴヌクレオチド製品
- 試薬
- 装置
- サービス
第7章 市場内訳：用途別
- PCRプライマー
- PCRアッセイとパネル
- シーケンシング
- DNAマイクロアレイ
- 蛍光in-situハイブリダイゼーション（FISH）
- アンチセンスオリゴヌクレオチド
- その他
第8章 市場内訳：最終用途別
- 製薬・バイオテクノロジー企業
- 病院と診断ラボ
- 学術研究機関
第9章 市場内訳：地域別
- 北米
- 米国
- カナダ
- アジア太平洋
- 中国
- 日本
- インド
- 韓国
- オーストラリア
- インドネシア
- その他
- 欧州
- ドイツ
- フランス
- 英国
- イタリア
- スペイン
- ロシア
- その他
- ラテンアメリカ
- ブラジル
- メキシコ
- その他
- 中東・アフリカ
- 市場動向
- 市場内訳：国別
- 市場予測
第10章 SWOT分析
- 概要
- 強み
- 弱み
- 機会
- 脅威
第11章 バリューチェーン分析
第12章 ポーターのファイブフォース分析
- 概要
- 買い手の交渉力
- 供給企業の交渉力
- 競合の程度
- 新規参入業者の脅威
- 代替品の脅威
第13章 価格分析
第14章 競合情勢
- 市場構造
- 主要企業
- 主要企業のプロファイル
- Agilent Technologies Inc.
- Biolegio B.V.
- Bio-Synthesis Inc
- Eurofins Genomics
- GenScript
- Horizon Discovery Ltd
- Integrated DNA Technologies Inc（Danaher Corporation）
- Kaneka Eurogentec S.A.（Kaneka Corporation）
- LGC Limited
- Nitto Denko Avecia Inc（Nitto Denko Corporation）
- Thermo Fisher Scientific Inc.
List of Figures
- Figure 1: Global: Oligonucleotide Synthesis Market: Major Drivers and Challenges
- Figure 2: Global: Oligonucleotide Synthesis Market: Sales Value (in Billion US$), 2018-2023
- Figure 3: Global: Oligonucleotide Synthesis Market Forecast: Sales Value (in Billion US$), 2024-2032
- Figure 4: Global: Oligonucleotide Synthesis Market: Breakup by Product (in %), 2023
- Figure 5: Global: Oligonucleotide Synthesis Market: Breakup by Application (in %), 2023
- Figure 6: Global: Oligonucleotide Synthesis Market: Breakup by End Use (in %), 2023
- Figure 7: Global: Oligonucleotide Synthesis Market: Breakup by Region (in %), 2023
- Figure 8: Global: Oligonucleotide Synthesis (Synthesized Oligonucleotide Products) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 9: Global: Oligonucleotide Synthesis (Synthesized Oligonucleotide Products) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 10: Global: Oligonucleotide Synthesis (Reagents) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 11: Global: Oligonucleotide Synthesis (Reagents) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 12: Global: Oligonucleotide Synthesis (Equipment) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 13: Global: Oligonucleotide Synthesis (Equipment) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 14: Global: Oligonucleotide Synthesis (Services) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 15: Global: Oligonucleotide Synthesis (Services) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 16: Global: Oligonucleotide Synthesis (PCR Primers) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 17: Global: Oligonucleotide Synthesis (PCR Primers) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 18: Global: Oligonucleotide Synthesis (PCR Assays and Panels) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 19: Global: Oligonucleotide Synthesis (PCR Assays and Panels) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 20: Global: Oligonucleotide Synthesis (Sequencing) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 21: Global: Oligonucleotide Synthesis (Sequencing) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 22: Global: Oligonucleotide Synthesis (DNA Microarrays) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 23: Global: Oligonucleotide Synthesis (DNA Microarrays) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 24: Global: Oligonucleotide Synthesis (Fluorescence In-Situ Hybridization (FISH)) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 25: Global: Oligonucleotide Synthesis (Fluorescence In-Situ Hybridization (FISH)) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 26: Global: Oligonucleotide Synthesis (Antisense Oligonucleotides) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 27: Global: Oligonucleotide Synthesis (Antisense Oligonucleotides) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 28: Global: Oligonucleotide Synthesis (Other Applications) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 29: Global: Oligonucleotide Synthesis (Other Applications) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 30: Global: Oligonucleotide Synthesis (Pharmaceutical and Biotechnology Companies) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 31: Global: Oligonucleotide Synthesis (Pharmaceutical and Biotechnology Companies) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 32: Global: Oligonucleotide Synthesis (Hospital and Diagnostic Laboratories) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 33: Global: Oligonucleotide Synthesis (Hospital and Diagnostic Laboratories) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 34: Global: Oligonucleotide Synthesis (Academic Research Institutes) Market: Sales Value (in Million US$), 2018 & 2023
- Figure 35: Global: Oligonucleotide Synthesis (Academic Research Institutes) Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 36: North America: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 37: North America: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 38: United States: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 39: United States: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 40: Canada: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 41: Canada: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 42: Asia-Pacific: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 43: Asia-Pacific: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 44: China: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 45: China: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 46: Japan: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 47: Japan: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 48: India: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 49: India: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 50: South Korea: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 51: South Korea: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 52: Australia: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 53: Australia: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 54: Indonesia: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 55: Indonesia: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 56: Others: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 57: Others: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 58: Europe: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 59: Europe: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 60: Germany: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 61: Germany: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 62: France: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 63: France: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 64: United Kingdom: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 65: United Kingdom: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 66: Italy: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 67: Italy: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 68: Spain: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 69: Spain: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 70: Russia: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 71: Russia: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 72: Others: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 73: Others: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 74: Latin America: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 75: Latin America: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 76: Brazil: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 77: Brazil: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 78: Mexico: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 79: Mexico: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 80: Others: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 81: Others: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 82: Middle East and Africa: Oligonucleotide Synthesis Market: Sales Value (in Million US$), 2018 & 2023
- Figure 83: Middle East and Africa: Oligonucleotide Synthesis Market: Breakup by Country (in %), 2023
- Figure 84: Middle East and Africa: Oligonucleotide Synthesis Market Forecast: Sales Value (in Million US$), 2024-2032
- Figure 85: Global: Oligonucleotide Synthesis Industry: SWOT Analysis
- Figure 86: Global: Oligonucleotide Synthesis Industry: Value Chain Analysis
- Figure 87: Global: Oligonucleotide Synthesis Industry: Porter's Five Forces Analysis
List of Tables
- Table 1: Global: Oligonucleotide Synthesis Market: Key Industry Highlights, 2023 and 2032
- Table 2: Global: Oligonucleotide Synthesis Market Forecast: Breakup by Product (in Million US$), 2024-2032
- Table 3: Global: Oligonucleotide Synthesis Market Forecast: Breakup by Application (in Million US$), 2024-2032
- Table 4: Global: Oligonucleotide Synthesis Market Forecast: Breakup by End Use (in Million US$), 2024-2032
- Table 5: Global: Oligonucleotide Synthesis Market Forecast: Breakup by Region (in Million US$), 2024-2032
- Table 6: Global: Oligonucleotide Synthesis Market: Competitive Structure
- Table 7: Global: Oligonucleotide Synthesis Market: Key Players
The global oligonucleotide synthesis market size reached US$ 3.0 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 8.0 Billion by 2032, exhibiting a growth rate (CAGR) of 11.1% during 2024-2032. The growing prevalence of genetic diseases among the masses, the development of novel therapeutic strategies, and the widespread adoption of therapies using small interfering RNAs (siRNAs), and antisense oligonucleotides are some of the major factors propelling the market.
Oligonucleotide synthesis refers to the process of constructing short DNA or RNA molecules, called oligonucleotides, in a predetermined sequence. These can range from just a few bases to around 200 nucleotides in length. The process is accomplished chemically in a controlled laboratory environment, typically using solid phase phosphoramidite chemistry. In this method, nucleotides are sequentially added to a growing chain, each addition involving a series of chemical reactions. This technology enables scientists to generate custom-made oligonucleotides for various applications including gene synthesis, polymerase chain reaction (PCR), gene editing tools, such as CRISPR-Cas9, and molecular diagnostic tests. Advances in oligonucleotide synthesis have dramatically accelerated research in genomics and molecular biology, underpinning many breakthroughs in medical and biological research.
The rising prevalence of genetic diseases among the masses majorly drives the global market. This necessitates the development of novel therapeutic strategies, where oligonucleotide-based therapies play a significant role. For instance, therapies using small interfering RNAs (siRNAs) and antisense oligonucleotides are being investigated and utilized in the treatment of genetic disorders, such as Duchenne muscular dystrophy and spinal muscular atrophy. As such, the growing prevalence of genetic diseases drives the demand on the global level. Along with this, the growth of bioinformatics and data science has a direct impact on the oligonucleotide synthesis industry. The escalating capacity to analyze large genomic datasets is also positively influencing the market. Therefore, the rising computational capability is driving an increased demand for the synthesis of novel oligonucleotides. Furthermore, oligonucleotides particularly antisense oligonucleotides, have been shown to be effective tools in epigenetic research and therapy, helping to modulate gene expression, which is creating a positive market outlook.
Oligonucleotide Synthesis Market Trends/Drivers:
Rising Demand in the Healthcare and Pharmaceutical Industries
The global demand for personalized medicine and therapeutics is rapidly increasing, leading to an unprecedented expansion in the oligonucleotide synthesis market. These synthesized sequences are integral components in developing targeted therapies for various genetic disorders and diseases, including cancer. Along with this, the advancement of therapeutic oligonucleotides, such as antisense oligonucleotides, aptamers, siRNAs, and immunostimulatory oligonucleotides, is revolutionizing disease treatment by specifically inhibiting or altering gene expression. Furthermore, the synthesis of custom oligonucleotides is fundamental to the production of vaccines, including mRNA-based COVID-19 vaccines, which have proven effective and are now widely used. As pharmaceutical companies and researchers continue to discover novel applications for oligonucleotides in the treatment and prevention of diseases, the demand for oligonucleotide synthesis is poised to rise.
Technological Advancements and Innovation
The steady development and refinement of oligonucleotide synthesis technologies are driving market growth. In addition, innovations in the synthesis process, including high-throughput and automated synthesis systems, have increased the efficiency, accuracy, and scalability of oligonucleotide production. Moreover, developments in bioinformatics and synthetic biology, including DNA sequencing and gene editing (e.g., CRISPR-Cas9), heavily rely on the ability to synthesize oligonucleotides accurately. These advancements allow for the creation of custom sequences with greater complexity and diversity and facilitate rapid prototype testing in synthetic biology, thereby fostering more efficient research and development. These continuous technological advancements and developments are also contributing to the market.
Growing Collaborations and Partnerships
Collaborations and partnerships between pharmaceutical companies, biotechnology firms, and research institutions have become essential drivers in advancing the development and commercialization of oligonucleotide therapies for genetic diseases. These collaborations bring together diverse expertise, resources, and funding, creating a synergistic environment that accelerates the translation of scientific discoveries into practical and effective treatments. Pharmaceutical companies, with their experience in drug development, clinical trials, and regulatory processes, contribute vital expertise to the collaboration. They have the infrastructure, knowledge, and resources necessary to navigate the complex landscape of drug development and ensure that oligonucleotide therapies meet regulatory standards for safety and efficacy. Their involvement helps streamline the path to commercialization by leveraging existing networks, manufacturing capabilities, and distribution channels.
Oligonucleotide Synthesis Industry Segmentation:
IMARC Group provides an analysis of the key trends in each segment of the global oligonucleotide synthesis market report, along with forecasts at the global, regional and country levels from 2024-2032. Our report has categorized the market based on product, application and end use.
Breakup by Product:
Synthesized Oligonucleotide Products
Reagents
Equipment
Services
Synthesized oligonucleotide products dominate the market
The report has provided a detailed breakup and analysis of the market based on the product. This includes synthesized oligonucleotide products, reagents, equipment, and services. According to the report, synthesized oligonucleotide products represented the largest segment.
The market for synthesized oligonucleotide products in the oligonucleotide synthesis industry is being driven by the ever-increasing demand from pharmaceutical and biotechnological companies for drug discovery and development, especially for personalized medicine and targeted therapeutics. Along with this, the rise in genomics and molecular research, fueled by significant advancements in technologies such as Next Generation Sequencing (NGS) and CRISPR gene-editing, is enhancing the requirement for synthesized oligonucleotides. Additionally, the growth in diagnostic applications of oligonucleotides, such as in PCR and microarray assays for genetic and infectious diseases, is propelling the market forward. The expanding field of epigenetics also represents a key driver, with oligonucleotides playing a crucial role in gene expression studies. Moreover, the increasing prevalence of genetic disorders and the resultant demand for novel therapeutic strategies involving oligonucleotides further accelerates the market growth for synthesized oligonucleotide products.
Breakup by Application:
PCR Primers
PCR Assays and Panels
Sequencing
DNA Microarrays
Fluorescence In-Situ Hybridization (FISH)
Antisense Oligonucleotides
Others
PCR primers dominate the market
A detailed breakup and analysis of the market based on the application has also been provided in the report. This includes PCR primers, PCR assays and panels, sequencing, DNA microarrays, Fluorescence In-Situ Hybridization (FISH), antisense oligonucleotides, and others. According to the report, the PCR primers represented the largest segment.
The demand for PCR primers in the oligonucleotide synthesis industry is driven by the ongoing global health crisis necessitating extensive viral testing, in which PCR is a primary method. Furthermore, the increasing application of PCR in medical diagnostics, forensics, and research to detect genetic mutations and infectious diseases fuels the demand for primers. In the field of genomics and molecular biology, PCR is considered a crucial tool for DNA sequencing, cloning, and genetic manipulation, and this broad utilization further drives the need for PCR primer synthesis. Apart from this, technological advancements in PCR techniques, such as real-time PCR and digital PCR, are also playing a role in boosting demand. Moreoevr, the growing funding for research in healthcare and life sciences has resulted in expanded use of PCR, thus driving the demand for PCR primers in the overall industry.
Breakup by End Use:
Pharmaceutical and Biotechnology Companies
Hospital and Diagnostic Laboratories
Academic Research Institutes
Academic research institutes dominate the market
The report has provided a detailed breakup and analysis of the market based on the end use. This includes pharmaceutical and biotechnology companies, hospital and diagnostic laboratories, and academic research institutes. According to the report, academic research institutes represented the largest segment.
The demand for oligonucleotide synthesis in academic research institutes is driven by a rise in genomics and molecular biology research, particularly studies related to gene expression, genetic disorders, and the development of novel therapeutic strategies. Additionally, advancements in technologies such as Next-Generation Sequencing (NGS) and CRISPR gene-editing, which rely on synthesized oligonucleotides, are stimulating demand. In addition, the rising trend of interdisciplinary studies involving bioinformatics and data science, which necessitate the use of oligonucleotides for data validation, further drives the need. Governmental and institutional funding for genomics and biotechnology research is another major driver, enabling academic institutes to invest in oligonucleotide synthesis for various projects. Academic research institutes, with their focus on fundamental research and discovery, often possess cutting-edge knowledge and innovative ideas. By partnering with industry, they can translate their scientific findings into practical applications and commercial products.
Breakup by Region:
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
North America exhibits a clear dominance, accounting for the largest oligonucleotide synthesis market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa.
The North American market for oligonucleotide synthesis is propelled by a robust pharmaceutical and biotech industry, with a strong focus on drug discovery and development. The region's emphasis on personalized medicine and targeted therapies further propels this need. Additionally, North America's sophisticated healthcare system with advanced diagnostic capabilities increases the demand for oligonucleotides in diagnostic assays. The region also hosts numerous top-tier academic and research institutes conducting extensive genomics and molecular biology research, which necessitates oligonucleotide synthesis. Moreover, strong governmental and private sector investment in healthcare and life sciences research, particularly in genomics and personalized medicine, fuels the growth of industry in North America. Moreover, the advancements in delivery systems and formulations for oligonucleotide-based therapeutics in North America demonstrate the region's commitment to pushing the boundaries of innovation in this field. These developments not only contribute to the growth of the market but also have the potential to revolutionize the treatment of various diseases, including genetic disorders, cancers, and rare diseases.
Competitive Landscape:
The global oligonucleotide synthesis market is experiencing significant growth due to the escalating investments in the development of new production facilities, upgrading existing ones, and implementing more efficient production processes. Therefore, Companies are heavily investing in research and development to innovate their offerings, including developing new synthesis techniques, improving the scale and accuracy of synthesis, and creating new types of oligonucleotide products to support various applications in diagnostics, therapeutics, and research. Along with this, companies are entering into strategic collaborations, partnerships, and acquisitions to co-develop oligonucleotide-based drugs, share technology and expertise, or expand into new markets. In addition, the introduction of therapeutics, such as antisense oligonucleotides, siRNAs, and miRNAs, offer new avenues for treating a wide range of diseases, including genetic disorders and cancers is positively influencing the market. Furthermore, key players are offering services for the custom synthesis of oligonucleotides. This allows researchers and developers to order specific oligonucleotide sequences tailored to their needs, which is particularly important in fields like genomics, molecular biology, and personalized medicine.
The report has provided a comprehensive analysis of the competitive landscape in the global oligonucleotide synthesis market. Detailed profiles of all major companies have also been provided. Some of the key players in the market include:
Agilent Technologies Inc.
Biolegio B.V.
Bio-Synthesis Inc
Eurofins Genomics
GenScript
Horizon Discovery Ltd
Integrated DNA Technologies Inc (Danaher Corporation)
Kaneka Eurogentec S.A. (Kaneka Corporation)
LGC Limited
Nitto Denko Avecia Inc (Nitto Denko Corporation)
Thermo Fisher Scientific Inc.
Recent Developments:
In May 2023, GenScript increased the size of its principal manufacturing plant in Zhenjiang, Jiangsu, China for the manufacture of oligonucleotides and peptides. The expansion builds on GenScript's history of providing top-notch oligo and peptides to scientists all across the world for 20 years.
In January 2023, Agilent Technologies Inc. announced to increase its production of therapeutic nucleic acids, also known as oligonucleotides. The initiative is the most recent in a series of investments done by the sector in response to rapid development. At Agilent's plant in Frederick, Colorado, where the installation of a line announced in 2020 is slated to commence operating later this year, the project will add two oligonucleotide production lines.
In February 2022, Kaneka Eurogentec S.A. (Kaneka Corporation) stated that a 25 g batch of mRNA for a US customer had been successfully manufactured at its mRNA synthesis facility. In its present facility in Belgium, Eurogentec's GMP mRNA production service provides in vitro transcription (IVT), purification, quality control, and batch release of GMP material up to 25 g scale.
Key Questions Answered in This Report
- 1. What was the size of the global oligonucleotide synthesis market in 2023?
- 2. What is the expected growth rate of the global oligonucleotide synthesis market during 2024-2032?
- 3. What are the key factors driving the global oligonucleotide synthesis market?
- 4. What has been the impact of COVID-19 on the global oligonucleotide synthesis market?
- 5. What is the breakup of the global oligonucleotide synthesis market based on the product?
- 6. What is the breakup of the global oligonucleotide synthesis market based on the application?
- 7. What is the breakup of the global oligonucleotide synthesis market based on end use?
- 8. What are the key regions in the global oligonucleotide synthesis market?
- 9. Who are the key players/companies in the global oligonucleotide synthesis market?
Table of Contents
1 Preface
2 Scope and Methodology
- 2.1 Objectives of the Study
- 2.2 Stakeholders
- 2.3 Data Sources
- 2.3.1 Primary Sources
- 2.3.2 Secondary Sources
- 2.4 Market Estimation
- 2.4.1 Bottom-Up Approach
- 2.4.2 Top-Down Approach
- 2.5 Forecasting Methodology
3 Executive Summary
4 Introduction
- 4.1 Overview
- 4.2 Key Industry Trends
5 Global Oligonucleotide Synthesis Market
- 5.1 Market Overview
- 5.2 Market Performance
- 5.3 Impact of COVID-19
- 5.4 Market Forecast
6 Market Breakup by Product
- 6.1 Synthesized Oligonucleotide Products
- 6.1.1 Market Trends
- 6.1.2 Market Forecast
- 6.2 Reagents
- 6.2.1 Market Trends
- 6.2.2 Market Forecast
- 6.3 Equipment
- 6.3.1 Market Trends
- 6.3.2 Market Forecast
- 6.4 Services
- 6.4.1 Market Trends
- 6.4.2 Market Forecast
7 Market Breakup by Application
- 7.1 PCR Primers
- 7.1.1 Market Trends
- 7.1.2 Market Forecast
- 7.2 PCR Assays and Panels
- 7.2.1 Market Trends
- 7.2.2 Market Forecast
- 7.3 Sequencing
- 7.3.1 Market Trends
- 7.3.2 Market Forecast
- 7.4 DNA Microarrays
- 7.4.1 Market Trends
- 7.4.2 Market Forecast
- 7.5 Fluorescence In-Situ Hybridization (FISH)
- 7.5.1 Market Trends
- 7.5.2 Market Forecast
- 7.6 Antisense Oligonucleotides
- 7.6.1 Market Trends
- 7.6.2 Market Forecast
- 7.7 Others
- 7.7.1 Market Trends
- 7.7.2 Market Forecast
8 Market Breakup by End Use
- 8.1 Pharmaceutical and Biotechnology Companies
- 8.1.1 Market Trends
- 8.1.2 Market Forecast
- 8.2 Hospital and Diagnostic Laboratories
- 8.2.1 Market Trends
- 8.2.2 Market Forecast
- 8.3 Academic Research Institutes
- 8.3.1 Market Trends
- 8.3.2 Market Forecast
9 Market Breakup by Region
- 9.1 North America
- 9.1.1 United States
- 9.1.1.1 Market Trends
- 9.1.1.2 Market Forecast
- 9.1.2 Canada
- 9.1.2.1 Market Trends
- 9.1.2.2 Market Forecast
- 9.1.1 United States
- 9.2 Asia-Pacific
- 9.2.1 China
- 9.2.1.1 Market Trends
- 9.2.1.2 Market Forecast
- 9.2.2 Japan
- 9.2.2.1 Market Trends
- 9.2.2.2 Market Forecast
- 9.2.3 India
- 9.2.3.1 Market Trends
- 9.2.3.2 Market Forecast
- 9.2.4 South Korea
- 9.2.4.1 Market Trends
- 9.2.4.2 Market Forecast
- 9.2.5 Australia
- 9.2.5.1 Market Trends
- 9.2.5.2 Market Forecast
- 9.2.6 Indonesia
- 9.2.6.1 Market Trends
- 9.2.6.2 Market Forecast
- 9.2.7 Others
- 9.2.7.1 Market Trends
- 9.2.7.2 Market Forecast
- 9.2.1 China
- 9.3 Europe
- 9.3.1 Germany
- 9.3.1.1 Market Trends
- 9.3.1.2 Market Forecast
- 9.3.2 France
- 9.3.2.1 Market Trends
- 9.3.2.2 Market Forecast
- 9.3.3 United Kingdom
- 9.3.3.1 Market Trends
- 9.3.3.2 Market Forecast
- 9.3.4 Italy
- 9.3.4.1 Market Trends
- 9.3.4.2 Market Forecast
- 9.3.5 Spain
- 9.3.5.1 Market Trends
- 9.3.5.2 Market Forecast
- 9.3.6 Russia
- 9.3.6.1 Market Trends
- 9.3.6.2 Market Forecast
- 9.3.7 Others
- 9.3.7.1 Market Trends
- 9.3.7.2 Market Forecast
- 9.3.1 Germany
- 9.4 Latin America
- 9.4.1 Brazil
- 9.4.1.1 Market Trends
- 9.4.1.2 Market Forecast
- 9.4.2 Mexico
- 9.4.2.1 Market Trends
- 9.4.2.2 Market Forecast
- 9.4.3 Others
- 9.4.3.1 Market Trends
- 9.4.3.2 Market Forecast
- 9.4.1 Brazil
- 9.5 Middle East and Africa
- 9.5.1 Market Trends
- 9.5.2 Market Breakup by Country
- 9.5.3 Market Forecast
10 SWOT Analysis
- 10.1 Overview
- 10.2 Strengths
- 10.3 Weaknesses
- 10.4 Opportunities
- 10.5 Threats
11 Value Chain Analysis
12 Porters Five Forces Analysis
- 12.1 Overview
- 12.2 Bargaining Power of Buyers
- 12.3 Bargaining Power of Suppliers
- 12.4 Degree of Competition
- 12.5 Threat of New Entrants
- 12.6 Threat of Substitutes
13 Price Analysis
14 Competitive Landscape
- 14.1 Market Structure
- 14.2 Key Players
- 14.3 Profiles of Key Players
- 14.3.1 Agilent Technologies Inc.
- 14.3.1.1 Company Overview
- 14.3.1.2 Product Portfolio
- 14.3.1.3 Financials
- 14.3.1.4 SWOT Analysis
- 14.3.2 Biolegio B.V.
- 14.3.2.1 Company Overview
- 14.3.2.2 Product Portfolio
- 14.3.3 Bio-Synthesis Inc
- 14.3.3.1 Company Overview
- 14.3.3.2 Product Portfolio
- 14.3.4 Eurofins Genomics
- 14.3.4.1 Company Overview
- 14.3.4.2 Product Portfolio
- 14.3.5 GenScript
- 14.3.5.1 Company Overview
- 14.3.5.2 Product Portfolio
- 14.3.6 Horizon Discovery Ltd
- 14.3.6.1 Company Overview
- 14.3.6.2 Product Portfolio
- 14.3.7 Integrated DNA Technologies Inc (Danaher Corporation)
- 14.3.7.1 Company Overview
- 14.3.7.2 Product Portfolio
- 14.3.8 Kaneka Eurogentec S.A. (Kaneka Corporation)
- 14.3.8.1 Company Overview
- 14.3.8.2 Product Portfolio
- 14.3.9 LGC Limited
- 14.3.9.1 Company Overview
- 14.3.9.2 Product Portfolio
- 14.3.10 Nitto Denko Avecia Inc (Nitto Denko Corporation)
- 14.3.10.1 Company Overview
- 14.3.10.2 Product Portfolio
- 14.3.11 Thermo Fisher Scientific Inc.
- 14.3.11.1 Company Overview
- 14.3.11.2 Product Portfolio
- 14.3.11.3 Financials
- 14.3.11.4 SWOT Analysis
- 14.3.1 Agilent Technologies Inc.
