in situ ハイブリダイゼーション (ISH) の市場規模・シェア・成長分析 (製品別、技術別、用途別、エンドユーザー別、地域別)：産業予測 (2025～2032年)

世界のin situ ハイブリダイゼーション (ISH) の市場規模は、2023年に21億米ドルと評価され、2024年の23億6,000万米ドルから2032年には60億6,000万米ドルに成長し、予測期間 (2025-2032年) のCAGRは12.5%で成長する見通しです。

in situ ハイブリダイゼーション (ISH) 市場は、分子診断、遺伝子編集、組換えDNA技術における極めて重要な役割により、大きな成長を遂げています。この技術は、細胞や組織内の核酸の局在と定量を可能にし、高い感度と精度を提供します。分子生物学、免疫学、発生生物学、血液病理学など多様な分野に応用され、特に疾病予後、創薬、バイオマーカー開発などの研究能力を高めてきました。ここ数年、PLISH (Proximity Ligation in situ Hybridization) のような、高性能、費用対効果、迅速な多重化を誇る技術の革新に向け、研究開発の多大な努力が払われてきました。このような進歩は、細胞機能のより深い理解を促進し、市場拡大をさらに後押ししています。

目次

イントロダクション

• 分析目的
• 市場範囲
• 定義

分析手法

• 情報調達
• 二次・一次データの手法
• 市場規模予測
• 市場の想定と制約

エグゼクティブサマリー

• 市場の概要と展望
• 需給動向の分析
• セグメント別の機会分析

市場力学と展望

• 市場概要
• 市場規模
• 市場力学
  • 促進要因と機会
  • 抑制要因と課題
• ポーター分析

市場の主な考察

• 主な成功要因
• 競合の程度
• 主な投資機会
• 市場エコシステム
• 市場魅力度指数 (2024年)
• PESTEL分析
• マクロ経済指標
• バリューチェーン分析
• 価格分析
• 技術分析
• 規制分析
• 特許分析
• ケーススタディ

世界のin situ ハイブリダイゼーション (ISH) の市場規模・CAGR：製品別 (2025～2032年)

• 市場概要
• 消耗品
  • プローブ
  • キット・試薬
  • アクセサリー
• 装置
• ソフトウェア

世界のin situ ハイブリダイゼーション (ISH) の市場規模・CAGR：技術別 (2025～2032年)

• 市場概要
• 蛍光in situハイブリダイゼーション
  • DNA蛍光in situハイブリダイゼーション
  • RNA蛍光in situハイブリダイゼーション
  • PNA蛍光in situハイブリダイゼーション
• 発色in situハイブリダイゼーション

世界のin situ ハイブリダイゼーション (ISH) の市場規模・CAGR：用途別 (2025～2032年)

• 市場概要
• がん診断
• 細胞学
• 感染症診断
• 神経科学
• 免疫学

世界のin situ ハイブリダイゼーション (ISH) の市場規模・CAGR：エンドユーザー別 (2025～2032年)

• 市場概要
• 病院・診断検査室
• 学術研究機関

世界のin situ ハイブリダイゼーション (ISH) の市場規模・CAGR (2025～2032年)

• 北米
  • 米国
  • カナダ
• 欧州
  • ドイツ
  • スペイン
  • フランス
  • 英国
  • イタリア
  • その他欧州地域
• アジア太平洋
  • 中国
  • インド
  • 日本
  • 韓国
  • その他アジア太平洋地域
• ラテンアメリカ
  • ブラジル
  • その他ラテンアメリカ地域
• 中東・アフリカ
  • GCC諸国
  • 南アフリカ
  • その他中東・アフリカ

競合情勢

• 上位5社の比較
• 主要企業の市場ポジショニング (2024年)
• 主要企業が採用した戦略
• 市場の近年の動向
• 主要企業の市場シェア (2024年)
• 主要企業のプロファイル
  • 企業概要
  • 製品ポートフォリオ分析
  • セグメント別シェア分析
  • 収益の前年比比較 (2022～2024年)

主要企業プロファイル

• Abbott (米国)
• F. Hoffmann-La Roche AG (スイス)
• Thermo Fisher Scientific Inc. (米国)
• Danaher (米国)
• Agilent Technologies, Inc. (米国)
• Biocare Medical, LLC (米国)
• Bio-Techne Corporation (米国)
• QIAGEN N.V. (オランダ)
• Merck KGaA (ドイツ)
• PerkinElmer (米国)
• Enzo Biochem (米国)
• Bio-Rad Laboratories (米国)
• Abnova Corporation (台湾)
• BioGenex Laboratories (米国)
• OpGen (米国)
• Bio SB (米国)
• Abcam (UK)
• Zytomed Systems GmbH (ドイツ)
• NeoGenomics Laboratories (米国)
• BioView (イスラエル)

結論と推奨事項

Global In Situ Hybridization ISH Market size was valued at USD 2.1 billion in 2023 and is poised to grow from USD 2.36 billion in 2024 to USD 6.06 billion by 2032, growing at a CAGR of 12.5% during the forecast period (2025-2032).

The market for in-situ hybridization (ISH) is experiencing significant growth due to its pivotal role in molecular diagnostics, gene editing, and recombinant DNA technology. This technique allows for the localization and quantification of nucleic acids within cells and tissues, offering high sensitivity and accuracy. Its application across diverse fields, including molecular biology, immunology, developmental biology, and hematopathology, has enhanced research capabilities, particularly in disease prognosis, drug discovery, and biomarker development. Over the past few years, substantial R&D efforts have been made to innovate technologies like Proximity Ligation in situ Hybridization, which boasts high performance, cost-effectiveness, and rapid multiplexing. Such advancements are fostering a deeper understanding of cellular functions, further driving market expansion.

Top-down and bottom-up approaches were used to estimate and validate the size of the Global In Situ Hybridization ISH Market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Global In Situ Hybridization ISH Market Segmental Analysis

Global In Situ Hybridization ISH Market is segmented by Product, Technology, Application, End-User and region. Based on Product, the market is segmented into Consumables, Instruments andSoftware. Based on Technology, the market is segmented into Fluorescent In Situ Hybridization and Chromogenic in Situ Hybridization. Based on Application, the market is segmented into Cancer Diagnostics, Cytology, Infectious Disease Diagnostics, Neuroscience and Immunology. Based on End-User, the market is segmented into Hospitals and Diagnostic Laboratories and Academic & Research Institutes. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Driver of the Global In Situ Hybridization ISH Market

The Global In Situ Hybridization (ISH) market is primarily driven by the alarming rise in cancer cases worldwide over recent years. Extensive research has unveiled recurrent genomic abnormalities as key contributors to various cancers. By integrating cytogenetic assays like ISH with DNA fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC), researchers are now armed with advanced diagnostic tools that enhance their capabilities in cancer studies. Direct imaging of gene expression at the RNA level sheds light on the dynamics between cancer cells and their microenvironment, facilitating the evolution of diagnostic approaches. According to GLOBOCAN, the projected surge in cancer cases-estimated to reach 29.5 million globally by 2040-alongside the sharp increase in hemophilia incidences, underscores the pressing need for innovative diagnostic solutions. The escalating demand for ISH techniques in laboratories for chromosomal abnormalities and infectious disease diagnosis further propels market growth, alongside rising health expenditures and the prevalence of chronic illnesses like cancer and Alzheimer's disease.

Restraints in the Global In Situ Hybridization ISH Market

The Global In Situ Hybridization (ISH) market faces significant restraints that may hinder revenue growth. Short-lived fluorophore molecules present challenges, as the fluorescence signal diminishes rapidly over time, making fluorescence in situ hybridization (FISH) a time-sensitive technique. Additionally, FISH struggles with the detection of unbalanced translocations and low clonal cell populations in cases of minimal residual disease after cancer treatment. Further limitations include its reduced sensitivity compared to immunohistochemistry, relatively fewer false-positive results, and the risk of sample contamination during PCR processes. As a result, ISH is becoming less favored for diagnosing diseases with low pathogen loads due to its high detection threshold.

Market Trends of the Global In Situ Hybridization ISH Market

The Global In Situ Hybridization (ISH) market is witnessing a dynamic upward trend driven by advancements aimed at enhancing sensitivity and specificity in hybridization techniques. Innovations such as strand displacement amplification and molecular beacons are broadening the applications of ISH across research and diagnostic settings. These technologies enable the precise detection of low copy number nucleic acids, making them invaluable in fields like oncology, genetics, and infectious disease testing. As the demand for accurate and early diagnostics rises, coupled with increasing investments in research initiatives, the ISH market is poised for significant growth, reflecting its critical role in molecular biology and pathology.

Table of Contents

Introduction

• Objectives of the Study
• Scope of the Report
• Definitions

Research Methodology

• Information Procurement
• Secondary & Primary Data Methods
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Global Market Outlook
• Supply & Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Overview
• Market Size
• Market Dynamics
  • Drivers & Opportunities
  • Restraints & Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of substitute
  • Bargaining power of buyers
  • Threat of new entrants
  • Bargaining power of suppliers

Key Market Insights

• Key Success Factors
• Degree of Competition
• Top Investment Pockets
• Market Ecosystem
• Market Attractiveness Index, 2024
• PESTEL Analysis
• Macro-Economic Indicators
• Value Chain Analysis
• Pricing Analysis
• Technology Analysis
• Regulatory Analysis
• Patent Analysis
• Case Studies

Global In Situ Hybridization ISH Market Size by Product & CAGR (2025-2032)

• Market Overview
• Consumables
  • Probes
  • Kits & Reagents
  • Accessories
• Instruments
• Software

Global In Situ Hybridization ISH Market Size by Technology & CAGR (2025-2032)

• Market Overview
• Fluorescent In Situ Hybridization
  • DNA Fluorescent in Situ Hybridization
  • RNA Fluorescent in Situ Hybridization
  • PNA Fluorescent in Situ Hybridization
• Chromogenic in Situ Hybridization

Global In Situ Hybridization ISH Market Size by Application & CAGR (2025-2032)

• Market Overview
• Cancer Diagnostics
• Cytology
• Infectious Disease Diagnostics
• Neuroscience
• Immunology

Global In Situ Hybridization ISH Market Size by End-User & CAGR (2025-2032)

• Market Overview
• Hospitals and Diagnostic Laboratories
• Academic & Research Institutes

Global In Situ Hybridization ISH Market Size & CAGR (2025-2032)

• North America (Product, Technology, Application, End-User)
  • US
  • Canada
• Europe (Product, Technology, Application, End-User)
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific (Product, Technology, Application, End-User)
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America (Product, Technology, Application, End-User)
  • Brazil
  • Rest of Latin America
• Middle East & Africa (Product, Technology, Application, End-User)
  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Competitive Intelligence

• Top 5 Player Comparison
• Market Positioning of Key Players, 2024
• Strategies Adopted by Key Market Players
• Recent Developments in the Market
• Company Market Share Analysis, 2024
• Company Profiles of All Key Players
  • Company Details
  • Product Portfolio Analysis
  • Company's Segmental Share Analysis
  • Revenue Y-O-Y Comparison (2022-2024)

Key Company Profiles

• Abbott (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• F. Hoffmann-La Roche AG (Switzerland)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Thermo Fisher Scientific Inc. (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Danaher (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Agilent Technologies, Inc. (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Biocare Medical, LLC (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio-Techne Corporation (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• QIAGEN N.V. (Netherlands)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• PerkinElmer (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Enzo Biochem (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio-Rad Laboratories (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Abnova Corporation (Taiwan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• BioGenex Laboratories (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• OpGen (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio SB (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Abcam (UK)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Zytomed Systems GmbH (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• NeoGenomics Laboratories (US)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• BioView (Israel)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments

Conclusion & Recommendations