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市場調査レポート
商品コード
1656921
in situハイブリダイゼーションの世界市場:洞察、競合情勢、市場予測:2032年In Situ Hybridization - Market Insights, Competitive Landscape, and Market Forecast - 2032 |
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in situハイブリダイゼーションの世界市場:洞察、競合情勢、市場予測:2032年 |
出版日: 2025年01月01日
発行: DelveInsight
ページ情報: 英文 150 Pages
納期: 2~10営業日
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in situハイブリダイゼーションの市場規模は、2024年には16億7,355万米ドルとなりました。同市場は、2025年から2032年までの予測期間中に7.12%のCAGRで拡大し、2032年には28億8,613万米ドルに達すると予測されています。in-situハイブリダイゼーションの需要は、主にがんと遺伝性疾患の有病率の上昇によって顕著に急増しています。加えて、神経疾患や感染症の動向もこの需要をさらに後押ししています。これと相まって、研究開発活動の活発化と資金調達がin situハイブリダイゼーション市場の成長軌道を後押しする重要な要因となっています。この成長動向は、2025年から2032年までの予測期間を通じて持続し、繁栄すると予想されます。
ISHは、ダウン症やエドワード症候群などの先天性疾患の診断に用いられます。調査によって、特定の遺伝子が組織や臓器でどのように発現しているかを分析し、発生プロセスや疾患、生理機能への関与に光を当てることができます。そのため、遺伝性疾患や何らかの希少疾患の罹患者数の増加は、市場の成長に寄与すると予想されます。例えば、世界経済フォーラムが2023年2月に発表した報告書によると、2019年には約4億7,500万人が希少疾患に罹患しており、これは世界人口の10%を占めています。今後5年以内に、約1,520万人が希少疾患の特定に特化した臨床ゲノム検査を受けると予想されています。
Johnson & Johnsonが2023年2月に発表した記事によると、2023年現在、世界全体で3億人以上が希少疾患に罹患していると推定されています。蛍光in situハイブリダイゼーション(FISH)は、染色体異常に起因する疾患の診断を助けるために病理医が使用する遺伝子検査技術です。したがって、遺伝性疾患や希少疾患の増加は、in situハイブリダイゼーションの広範な使用に寄与しており、これが市場成長を促進すると予想されます。
世界保健機関(WHO)が2022年に発表したデータによると、2020年には世界中で乳がん約226万例、肺がん221万例、結腸・直腸がん193万例、前立腺がん141万例、胃がん109万例が報告されています。
2021年にGlobal Cancer Observatoryが発表したデータによると、2020年には世界中で約54万4,352例の非ホジキンリンパ腫と8万3,087例のホジキンリンパ腫が報告されました。同じ情報源によると、2020年には世界中で約474,519例の白血病と約176,404例の多発性骨髄腫が報告されています。In situハイブリダイゼーションは、がんに関連する遺伝子発現の変化や染色体異常を調べる貴重なツールとして機能し、潜在的な診断指標や治療介入の標的の発見に役立ち、市場の成長を促進しています。
HIVや肝炎などの感染症が増加していることも、in situハイブリダイゼーション(ISH)市場の主要な促進要因です。in situハイブリダイゼーション(ISH)は、感染性病原体を検出するために、実験室医学と分子遺伝学技術を融合させたものです。蛍光in situハイブリダイゼーション(FISH)は特に、細胞構造の完全性を維持しながら、多様なサンプル内のヌクレオチド配列を同定し、ピンポイントで特定するのに役立ちます。世界保健機関(WHO)の2022年の発表によると、2022年には全世界で約3億5,400万人がB型またはC型肝炎に感染していると推定されています。
政府の支援と資金は、希少疾病パートナーシップから得られる価値を最大化することに向けられており、その包括的な目標は、希少疾病分野における研究と技術革新のレベルを向上させることです。例えば、2023年9月、英国の研究・イノベーション部門は、総額約7億9,850万米ドル(6億2,700万英ポンド)の投資を行い、希少疾患研究の推進を目的とした様々なイニシアチブを包含しています。特に、2016年から2021年の間に1億2,690万米ドル(9,970万英ポンド)がMRCフェローシップとNIHRキャリア開発賞に割り当てられており、希少疾患研究の取り組みを取り巻く包括的な支援ネットワークが示されています。
当レポートでは、世界のin situハイブリダイゼーション市場について調査し、市場の概要とともに、製品タイプ別、技術別、用途別、エンドユーザー別、地域別動向、および市場に参入する企業のプロファイルなどを提供しています。
In Situ Hybridization Market by Product Type (Instruments, Reagents & Kits, and Software), Technology (Fluorescence In Situ Hybridization (FISH), Chromogenic In Situ Hybridization (CISH), and Others), Application (Cancer Diagnosis, Genetic Diseases, Infectious Diseases, and Others), End-User (Hospitals and Clinics, Diagnostic Centers, Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, and Others), and Geography (North America, Europe, Asia-Pacific, and Rest of the World) is expected to grow at a steady CAGR forecast till 2032 owing to the growing prevalence of cancer and genetic diseases and increasing incidences of neurological disorders and infectious disease
The in situ hybridization market was valued at USD 1,673.55 million in 2024, growing at a CAGR of 7.12% during the forecast period from 2025 to 2032 to reach USD 2,886.13 million by 2032. The demand for in situ hybridization is witnessing a notable surge, driven predominantly by the escalating prevalence of cancer and genetic diseases. Additionally, the upward trend in neurological disorders and infectious diseases further fuels this demand. Coupled with this, the intensifying R&D activities and funding are pivotal factors propelling the positive growth trajectory of the in situ hybridization market. This growth trend is expected to persist and flourish throughout the forecast period spanning from 2025 to 2032.
In Situ Hybridization Market Dynamics:
ISH is used to diagnose congenital diseases such as Down's syndrome and Edward's Syndrome. It enables researchers to analyze how certain genes are expressed in tissues or organs, shedding light on their involvement in developmental processes, diseases, and physiological functions. Therefore, the rising number of people affected by genetic or some kind of rare disease is expected to contribute to the growth of the market. For instance, a report by the World Economic Forum in February 2023, stated that approximately 475 million individuals were suffering from rare conditions in 2019 which comprised 10% of the global population. Within the upcoming five years, it was anticipated that around 15.2 million people were expected to undergo clinical genomic testing specifically aimed at identifying rare conditions.
According to an article shared by Johnson & Johnson in February 2023, the estimate suggests that over 300 million individuals were affected with rare diseases as of 2023 globally. Fluorescence in situ hybridization (FISH) is a genetic testing technique used by pathologists to aid in diagnosing diseases attributed to chromosomal abnormalities. Therefore, the growing genetic and rare diseases contribute to the extensive use of in situ hybridization which is expected to drive the market growth.
According to data cited by the World Health Organization in 2022, around 2.26 million cases of breast, 2.21 million cases of lung, 1.93 million cases of colon and rectum, 1.41 million cases of prostate, and 1.09 million cases of stomach cancer were reported in 2020 around the world.
As per data published by Global Cancer Observatory in 2021, around 544,352 cases of non-Hodgkin lymphoma and 83,087 cases of Hodgkin lymphoma were reported in 2020 worldwide. As per the same source, around 474,519 leukemia cases and nearly 176,404 cases of multiple myeloma were reported in 2020 across the globe. In situ hybridization serves as a valuable tool in examining changes in gene expression or chromosomal irregularities linked to cancer, aiding in the discovery of potential diagnostic indicators and targets for therapeutic intervention, thereby driving market growth.
The rising cases of infectious diseases such as HIV, hepatitis, and others is another key driver for the in situ hybridization (ISH) market. In situ hybridization (ISH) amalgamates laboratory medicine with molecular genetics technology to detect infectious pathogens. Fluorescence in situ hybridization (FISH) specifically aids in identifying and pinpointing nucleotide sequences within diverse samples, all while maintaining the integrity of cellular structures. According to the World Health Organization (WHO) 2022, it was estimated that around 354 million people were living with Hepatitis B or C infections in 2022 globally.
Government support and funding are directed towards maximizing the value derived from the Rare Diseases Partnership, with the overarching goal of fostering increased levels of research and innovation in the field of rare diseases. For instance, in September 2023, UK Research and Innovation, the investment, totaling nearly USD 798.5 million (GBP 627 million), encompasses various initiatives aimed at advancing rare disease research. Notably, USD 126.9 million (GBP 99.7 million) had been allocated to MRC fellowships and NIHR career development awards between 2016 and 2021, illustrating the comprehensive support network surrounding rare disease research efforts.
However, the in situ hybridization market may face growth constraints due to various factors, including the inefficiency of detecting DNA level rearrangements and chromosome pairs and concerns regarding potential exposure to radioactivity.
In Situ Hybridization Market Segment Analysis:
In Situ Hybridization Market by Product Type (Instruments, Reagents & Kits, and Software), Technology (Fluorescence In Situ Hybridization (FISH), Chromogenic In Situ Hybridization (CISH), and Others), Application (Cancer Diagnosis, Genetic Diseases, Infectious Diseases, and Others), End-User (Hospitals and Clinics, Diagnostic Centers, Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, and Others), and Geography (North America, Europe, Asia-Pacific, and Rest of the World)
In the technology segment of the in situ hybridization market, the fluorescence in situ hybridization (FISH) category is estimated to account for a significant revenue share in the in situ hybridization market in 2024. This is attributed to the growing use of FISH in cancer diagnosis and research. In oncology, FISH is utilized to identify genetic changes linked with cancer, including gene amplifications, deletions, and rearrangements of chromosomes. Fluorescence in situ hybridization (FISH) is mainly used in the diagnosis, categorization, prognosis, and anticipation of treatment outcomes in cancer patients.
The application of FISH spans a broad spectrum of scientific disciplines, including genetic counseling, subcellular studies, detection and localization of chromosome mutations, species identification, biomedical research, clinical diagnosis, toxicology, chromosomal biology, and comparative genomics.
Key players in the market are developing innovative kits and reagents for fluorescence in situ hybridization (FISH) procedures. For instance, in December 2021, BioGenex, a US-based molecular pathology company launched NanoVIP. NanoVIP is a compact, fully automated bench-top system equipped with visualization kits designed for fluorescence in situ hybridization (FISH) and in-situ hybridization (ISH). Its 10-slide design ensures reliability through automation, featuring eXACT(TM) temperature control modules for individual slide positions, precise management of reaction times, and liquid level sensors for accurate liquid handling. This meticulous control ensures the delivery of clean, intense, reliable, and reproducible stains, minimizing the need for repeat procedures.
Further, in cellular biology and neuroscience, scientists utilize techniques such as fluorescence in situ hybridization (FISH) to investigate the expression, localization, and dynamics of genes within cells and tissues. This method allows for the visualization of specific genes or RNA molecules in various cell types including neuronal cells, glial cells, and others. By studying gene expression patterns and their spatial distribution, researchers gain valuable insights into brain function, development, and the underlying mechanisms of neurological disorders. Additionally, FISH can aid in the diagnosis of genetic disorders by enabling the visualization of specific chromosomal regions or genes associated with these conditions. Therefore, the wide applications of the fluorescence in situ hybridization (FISH) category is expected to contribute to the growth of the segment, thereby driving the growth of the in situ hybridization market during the forecast period.
North America is expected to dominate the Overall In-Situ Hybridization Market:
North America is estimated to dominate the in situ hybridization market in 2024. This is attributed to the growing prevalence of cancer and rare genetic diseases. In situ hybridization (ISH) stands as a pivotal tool in cancer research and diagnosis, facilitating the detection of gene expression and genetic abnormalities linked with cancer. These capabilities significantly contribute to the growth of the market in the region. Moreover, the escalating number of molecular diagnostics tests conducted in the region further propels the expansion of the North America in situ hybridization market.
Fluorescence in situ hybridization (FISH) is a diagnostic test that maps the genetic material within human cells, pinpointing specific genes or gene segments. Due to its capability to detect genetic abnormalities linked to cancer, FISH serves as a valuable tool in diagnosing certain types of the disease. For instance, according to the National Cancer Institute 2020, it was estimated that around 1,806,590 cancer cases were diagnosed in the year 2020 in the United States.
According to the Centers for Disease Control and Prevention (CDC) in May 2024, approximately 5,700 babies were born with Down syndrome each year in the United States. This equates to a prevalence of about 1 in every 640 babies. In situ hybridization is used to identify an extra chromosome or an extra piece of a chromosome for diagnosis of Down syndrome. Therefore, the growing prevalence of rare and genetic diseases is expected to drive the market growth in the region.
In Situ Hybridization Market Key Players:
Some of the key market players operating in the in situ hybridization market include Abbott Laboratories, Agilent Technologies, Inc., Thermo Fisher Scientific Inc., F. Hoffmann-La Roche Ltd, Merck & Co., Inc., PerkinElmer Inc., Sysmex Corporation, Biocare Medical, LLC, Genemed Biotechnologies, Inc., NeoGenomics Laboratories, Advanced Cell Diagnostics, Inc., BioView, Bio-Rad Laboratories, Inc., Bio-Techne, QIAGEN, BioGenex, ZYTOVISION GmbH, Promega Corporation, Illumina, Inc., Danaher Corporation, and others.
Recent Developmental Activities in the In-Situ Hybridization Market:
Key Takeaways from the In Situ Hybridization Market Report Study
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FREQUENTLY ASKED QUESTIONS FOR THE IN SITU HYBRIDIZATION MARKET: