市場調査レポート

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1458105

ダウンストリーム加工の世界市場規模、シェア、成長分析、製品別、技術別 - 産業予測、2024年～2031年

Global Downstream Processing Market Size, Share, Growth Analysis, By Product(Chromatography Systems, Filters), By Technique(Cell Disruption, Solid-Liquid Separation) - Industry Forecast 2024-2031

出版日: 2024年03月27日 | 発行: SkyQuest

| ページ情報: 英文 219 Pages | 納期: 3～5営業日

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概要
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概要

サンプル依頼リストに入れる

世界のダウンストリーム加工市場規模は2022年に309億8,000万米ドルと評価され、予測期間（2024年～2031年）のCAGRは15.21%で、2023年の356億9,000万米ドルから2031年には1,107億9,000万米ドルに成長する見通しです。

ダウンストリーム加工では、生合成製品、特に医薬品が、発酵ブロス、植物組織、動物組織などの天然源から抽出・精製されます。この工程では、廃棄物の安全な処理だけでなく、再利用可能な成分のリサイクルも行われます。ホルモン剤、ワクチン（インスリンやヒト成長ホルモンなど）、抗体（インフリキシマブやアブシキシマブなど）、抗生物質などの医薬品を製造する上で極めて重要な工程となっています。例えば、2022年4月、メルクと無錫国家高新技術産業開発区は協力協定を締結し、中国江蘇省無錫市にあるメルクの製造工場の拡張につながった。川下処理には、化学的、物理的、生物学的技術を利用した細胞分離、ろ過、製品回収、抽出、精製など、製品を処理するさまざまな手順が含まれます。その結果、ワクチン、組換えタンパク質や酵素、抗生物質、抗体、ホルモン、診断用酵素、工業用酵素、天然香料やフレーバー化合物などの生物学的製品や医薬品が生み出されます。バイオプロセス能力の拡大、バイオプロセスにおけるシングルユース技術の受け入れ拡大、製薬会社における研究開発費の増加、バイオ医薬品市場における需要の拡大など、いくつかの要因がバイオ医薬品の世界の需要を牽引しています。有望な見通しとは裏腹に、世界のダウンストリーム・プロセシング市場には、ダウンストリーム・プロセシング機器や消耗品の高コストなど、成長を阻害しかねない課題が存在します。中小のバイオ企業や新興企業にとって、このような初期設備投資は法外であり、市場の拡大を制限する可能性があります。とはいえ、クロマトグラフィーやろ過技術の進歩により、下流処理の効率と拡張性が向上し、費用対効果が高まっています。さらに、バイオ製造におけるシングルユースやディスポーザブル技術の動向は、ダウンストリームを簡素化し、交差汚染のリスクを低減し、生産を加速しているため、市場の成長を促進しています。

技術分析
価格分析
サプライチェーン分析
バリューチェーン分析
市場のエコシステム
IP分析
貿易分析
スタートアップ分析
原材料の分析
イノベーションマトリクス
パイプライン製品の分析
マクロ経済指標
主な投資の分析
主な成功要因
競合の程度

市場力学と見通し

市場力学
- 促進要因
- 機会
- 抑制要因
- 課題
規制情勢
ポーターの分析
将来の混乱についての特別な考察

ダウンストリーム加工の世界市場：製品別

市場概要
クロマトグラフィーシステム
フィルター
蒸発器
遠心分離機
乾燥機

ダウンストリーム加工の世界市場：技術別

市場概要
細胞破壊
固液分離
集中
クロマトグラフィーによる精製
配合

ダウンストリーム加工の世界市場規模：地域別

市場概要
北米
- 米国
- カナダ
欧州
- ドイツ
- スペイン
- フランス
- 英国
- その他の欧州
アジア太平洋
- 中国
- インド
- 日本
- 韓国
- その他のアジア太平洋
ラテンアメリカ
- ブラジル
- その他のラテンアメリカ
中東・アフリカ（MEA）
- GCC諸国
- 南アフリカ
- その他の中東・アフリカ

競合情勢

上位5社の比較
主要企業の市場ポジショニング（2021年）
主な市場企業が採用した戦略
主要成功戦略
市場における最近の活動
主要企業の市場シェア（2021年）

主要企業プロファイル

Thermo Fisher Scientific Inc.（United States）
GE Healthcare（United States）
Merck KGaA（Germany）
Sartorius AG（Germany）
Danaher Corporation（United States）
3M Company（United States）
MilliporeSigma（United States）
Novasep Holding S.A.S.（France）
Lonza Group Ltd.（Switzerland）
Eppendorf AG（Germany）
Repligen Corporation（United States）
Charles River Laboratories International, Inc.（United States）
Boehringer Ingelheim International GmbH（Germany）
Avantor, Inc.（United States）
Corning Incorporated（United States）
Pall Corporation（United States）
Shimadzu Corporation（Japan）
Agilent Technologies, Inc.（United States）
ABEC, Inc.（United States）
Nova Biomedical（United States）
JSR Corporation（Japan）
NIZO（Netherlands）

Product Code: SQMIG35H2109

Global downstream processing market size was valued at USD 30.98 billion in 2022 and is poised to grow from USD 35.69 billion in 2023 to USD 110.79 billion by 2031, at a CAGR of 15.21% during the forecast period (2024-2031).

In downstream processing, biosynthetic products, particularly pharmaceuticals, are extracted and refined from natural sources such as fermentation broth, plant tissues, and animal tissues. This process involves not only the safe disposal of waste but also the recycling of reusable components. It serves as a crucial step in the production of drugs like hormones, vaccines (such as insulin and human growth hormone), antibodies (like infliximab and abciximab), and antibiotics. For example, in April 2022, Merck and Wuxi National High-tech Industrial Development Zone entered into a collaboration agreement, leading to the expansion of Merck's manufacturing plant in Wuxi, Jiangsu Province, China. Downstream processing encompasses various procedures to treat the product, including cell separation, filtration, product recovery, extraction, and purification, utilizing chemical, physical, and biological techniques. It results in the creation of biological and pharmaceutical products such as vaccines, recombinant proteins and enzymes, antibiotics, antibodies, hormones, diagnostic enzymes, industrial enzymes, as well as natural fragrance and flavor compounds. Several factors are driving the global demand for biopharmaceuticals, including expanding bioprocessing capacity, increasing acceptance of single-use technology in bioprocessing, rising R&D spending in pharmaceutical companies, and growing demand in the biopharmaceutical market. Despite the promising outlook, the Global Downstream Processing Market encounters challenges that could impede its growth, including the high cost of downstream processing equipment and consumables. This initial capital investment might be prohibitive for smaller biotech firms and startups, potentially limiting market expansion. Nevertheless, advancements in chromatography and filtration techniques are improving the efficiency and scalability of downstream processing, making it more cost-effective. Additionally, the trend towards single-use and disposable technologies in biomanufacturing is simplifying downstream processes, reducing the risk of cross-contamination, and accelerating production, thus driving market growth.

Top-down and bottom-up approaches were used to estimate and validate the size of the global downstream processing market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Global Downstream Processing Market Segmental Analysis

The global downstream processing market is segmented based on product, technique, application and region. By product, the market is segmented into chromatography systems, filters, evaporators, centrifuges, and dryers. By technique, market is segmented into cell disruption, solid-liquid separation, concentration, purification by chromatography, and formulation. By application, the market is segmented into antibiotic production, hormone production, antibodies production, enzyme production, and vaccine production. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Drivers of the Global Downstream Processing Market

The demand for biopharmaceuticals, including monoclonal antibodies, vaccines, and recombinant proteins, has been consistently increasing. Downstream processing is essential for purifying and isolating these intricate biological products, guaranteeing their safety and effectiveness. With the continuous expansion of the biopharmaceutical industry, there is a growing need for downstream processing technologies and equipment.

Restraints in the Global Downstream Processing Market

Every biopharmaceutical product possesses distinct characteristics, including size, charge, solubility, and stability, which can pose challenges during downstream processing. Certain products may have low yields, undergo challenging purification, or be prone to degradation throughout purification stages. Creating customized downstream processes for individual products and tackling product-specific obstacles can be intricate and demand substantial expertise and optimization endeavors.

Market Trends of the Global Downstream Processing Market

Process intensification entails enhancing downstream processing operations to attain higher productivity, enhanced yield, and decreased processing durations. Continuous manufacturing methods, such as continuous chromatography and continuous centrifugation, are becoming increasingly popular due to their ability to facilitate real-time monitoring, process control, and heightened process efficiency. These trends aim to simplify and abbreviate the entire downstream processing timeline, resulting in amplified productivity and cost reductions.

Executive Summary

Market Overview
Wheel of Fortune

Research Methodology

Information Procurement
Secondary & Primary Data Sources
Market Size Estimation
Market Assumptions & Limitations

Parent Market Analysis

Market Overview
Market Size
Market Dynamics
- Drivers
- Opportunities
- Restraints
- Challenges

Key Market Insights

Technology Analysis
Pricing Analysis
Supply Chain Analysis
Value Chain Analysis
Ecosystem of the Market
IP Analysis
Trade Analysis
Startup Analysis
Raw Material Analysis
Innovation Matrix
Pipeline Product Analysis
Macroeconomic Indicators
Top Investment Analysis
Key Success Factor
Degree of Competition

Market Dynamics & Outlook

Market Dynamics
- Drivers
- Opportunities
- Restraints
- Challenges
Regulatory Landscape
Porters Analysis
- Competitive rivalry
- Threat of Substitute Products
- Bargaining Power of Buyers
- Threat of New Entrants
- Bargaining Power of Suppliers
Skyquest Special Insights on Future Disruptions
- Political Impact
- Economic Impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact

Global Downstream Processing Market by Product

Market Overview
Chromatography Systems
Filters
Evaporators
Centrifuges
Dryers

Global Downstream Processing Market by Technique

Market Overview
Cell Disruption
Solid-Liquid Separation
Concentration
Purification by Chromatography
Formulation

Global Downstream Processing Market Size by Region

Market Overview
North America
- USA
- Canada
Europe
- Germany
- Spain
- France
- UK
- Rest of Europe
Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of Asia-Pacific
Latin America
- Brazil
- Rest of Latin America
Middle East & Africa (MEA)
- GCC Countries
- South Africa
- Rest of MEA

Competitive Landscape

Top 5 Player Comparison
Market Positioning of Key Players, 2021
Strategies Adopted by Key Market Players
Top Winning Strategies
- By Development
- By Company
- By Year
Recent Activities in the Market
Key Companies Market Share (%), 2021

Key Company Profiles

Thermo Fisher Scientific Inc. (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
GE Healthcare (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Merck KGaA (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Sartorius AG (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Danaher Corporation (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
3M Company (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
MilliporeSigma (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Novasep Holding S.A.S. (France)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Lonza Group Ltd. (Switzerland)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Eppendorf AG (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Repligen Corporation (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Charles River Laboratories International, Inc. (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Boehringer Ingelheim International GmbH (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Avantor, Inc. (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Corning Incorporated (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Pall Corporation (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Shimadzu Corporation (Japan)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Agilent Technologies, Inc. (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
ABEC, Inc. (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Nova Biomedical (United States)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
JSR Corporation (Japan)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
NIZO (Netherlands)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments