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市場調査レポート
商品コード
1625427
CAR-T細胞療法市場、規模、シェア、動向、産業分析レポート:適応症別、標的抗原別、地域別 - 市場予測、2025年~2034年CAR-T Cell Therapy Market Size, Share, Trends, Industry Analysis Report: By Indication, Target Antigen, and Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Market Forecast, 2025-2034 |
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CAR-T細胞療法市場、規模、シェア、動向、産業分析レポート:適応症別、標的抗原別、地域別 - 市場予測、2025年~2034年 |
出版日: 2024年12月01日
発行: Polaris Market Research
ページ情報: 英文 116 Pages
納期: 即日から翌営業日
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Polaris Market Researchの最新調査によると、世界のCAR-T細胞療法市場規模は2034年までに1,888億4,000万米ドルに達する見込みです。本レポートは、現在の市場力学を詳細に洞察し、将来の市場成長に関する分析を提供しています。
キメラ抗原受容体T細胞(CAR-T)療法は、がん治療の進歩を象徴し、免疫腫瘍学を一変させました。この治療は、特定のがん抗原を標的とする合成レセプターを発現するように患者のT細胞を操作することで、特定のがん、特に血液悪性腫瘍に対して個別化された非常に効果的な治療オプションを提供します。世界のCAR-T細胞療法市場は、バイオテクノロジーの急速な進歩、CAR-T療法の承認率の上昇、革新的ながん治療に対する需要の高まりなどを背景に、過去10年間で急激な成長を遂げてきました。
世界のがん罹患率の増加と精密医療への選好の高まりが、CAR-T細胞療法のような先進的治療法への需要を煽っています。さらに、支持的な規制の枠組みと迅速な承認経路が、CAR-T療法の利用可能性を加速させています。政府および民間の研究投資は、CAR-T細胞療法市場の拡大をさらに後押ししています。
マルチターゲットCAR-T細胞やアーマードCAR-T細胞を含む次世代CAR-T療法の開発が、CAR-T細胞療法市場の成長を促進しています。マルチターゲットCAR-T細胞は複数の抗原を認識するように設計されており、従来のCAR-T治療の有効性を制限していた腫瘍の不均一性や抗原逃避などの問題に対処します。武装化CAR-T細胞は、サイトカインやその他の分子を分泌して抗腫瘍活性を高めることにより、免疫抑制的な腫瘍微小環境を克服するように設計されています。
CAR-T療法の応用は腫瘍学以外にも広がっています。研究者たちは、ループスや多発性硬化症などの自己免疫疾患や、HIVなどの感染症の治療における可能性を探っています。こうした新たな応用は、市場の範囲と影響力を大幅に拡大すると推定されます。
適応症別では、濾胞性リンパ腫(FL)分野が最も速いペースで成長すると予測され、予測期間中のCAGRは43.2%です。
標的抗原に基づくと、CD19/CD22抗原セグメントは、びまん性大細胞型B細胞リンパ腫(DLBCL)や急性リンパ芽球性白血病(ALL)などのB細胞悪性腫瘍の治療において確立された役割により、2024年に6兆2,585億米ドルと評価され、最大の市場シェアを占めました。
世界市場では、北米のCAR-T細胞療法市場が2024年に47.16%の市場シェアを占めました。これは、高度なヘルスケアインフラの存在、多額の研究開発投資、血液悪性腫瘍の高い有病率によるものです。
欧州のCAR-T細胞療法市場は、再発または難治性の血液がんの有病率の上昇に加え、先進治療へのアクセス拡大への注目が高まっていることから、予測期間中に33.2%のCAGRが見込まれています。
世界の主要市場企業の一例としては、Bluebird Bio、Celgene Corporation、Gilead Sciences、Cellectis、Servier Laboratories、Pfizer Inc.、Merck、Amgen、Intellia Therapeutics、Novartis、Caribou Biosciences、Celyad、Bellicum Pharmaceuticals、Noile-Immune Biotech、Nanjing Legend Biotechnology Co.などが挙げられます。
Table 1 Selected significant catalysts in CAR-T
Table 2 Various antigen targets are investigated for solid tumors
Table 3 Top Developers in CAR T cell clinical trials (September 2019)
Table 4 Catalyst for Small Players
Table 5 Selected deals and partnerships
Table 6 Cost of production (Lentivirus), 2022, (USD Billion)
Table 7 Cost of production (Plasmid), 2022, (USD Billion)
Table 8 Reimbursement amounts for CAR-T therapies per region, 2022, (USD Billion)
Table 9 Global CAR-T Cell Therapy Market, by Indication, 2020-2034, (USD Billion)
Table 10 Global CAR-T Cell Therapy Market, by DLBCL, 2020-2034, (USD Billion)
Table 11 Global CAR-T Cell Therapy Market, by ALL, 2020-2034, (USD Billion)
Table 12 Global CAR-T Cell Therapy Market, by CLL, 2020-2034, (USD Billion)
Table 13 Global CAR-T Cell Therapy Market, by MM, 2020-2034, (USD Billion)
Table 14 Global CAR-T Cell Therapy Market, by FL, 2020-2034, (USD Billion)
Table 15 Global CAR-T Cell Therapy Market, by Mastozytosis, 2020-2034, (USD Billion)
Table 16 Global CAR-T Cell Therapy Market, by Myeloid Fibrosis, 2020-2034, (USD Billion)
Table 17 Global CAR-T Cell Therapy Market, by MLL, 2020-2034, (USD Billion)
Table 18 Global CAR-T Cell Therapy Market, by Thymic Cancer, 2020-2034, (USD Billion)
Table 19 Global CAR-T Cell Therapy Market, by Glioblastoma, 2020-2034, (USD Billion)
Table 20 Global CAR-T Cell Therapy Market, by AML, 2020-2034, (USD Billion)
Table 21 Global CAR-T Cell Therapy Market, by Other Indications, 2020-2034, (USD Billion)
The global CAR-T cell therapy market size is expected to reach USD 188.84 billion by 2034, according to a new study by Polaris Market Research. The report "CAR-T Cell Therapy Market Size, Share, Trends, Industry Analysis Report: By Indication, Target Antigen [CD19/CD22, BCMA (B-Cell Maturation Antigen), and Others], and Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Market Forecast, 2025-2034" gives a detailed insight into current market dynamics and provides analysis on future market growth.
Chimeric Antigen Receptor T-cell (CAR-T) therapy represents an advancement in cancer treatment, transforming immuno-oncology. The therapy offers personalized and highly effective treatment options for certain cancers, particularly hematological malignancies, by engineering a patient's T-cells to express synthetic receptors that target specific cancer antigens. The global CAR-T cell therapy market has witnessed exponential growth over the last decade, driven by rapid advancements in biotechnology, increasing approval rates of CAR-T therapies, and rising demand for innovative cancer treatments.
The increasing prevalence of cancer globally, coupled with a growing preference for precision medicine, has fueled demand for advanced treatment modalities such as CAR-T cell therapy. Moreover, supportive regulatory frameworks and rapid approval pathways have accelerated the availability of CAR-T therapies. Government and private investments in research further propel the CAR-T cell therapy market expansion.
The development of next-generation CAR-T therapies, including multi-target CAR-T cells and armored CAR-T cells, is driving the CAR-T cell therapy market growth. Multi-target CAR-T cells are engineered to recognize multiple antigens, addressing issues such as tumor heterogeneity and antigen escape, which limit the efficacy of traditional CAR-T treatments. Armored CAR-T cells are designed to overcome the immunosuppressive tumor microenvironment by secreting cytokines or other molecules to enhance anti-tumor activity.
The application of CAR-T therapy is expanding beyond oncology. Researchers are exploring its potential in treating autoimmune diseases such as lupus and multiple sclerosis and infectious diseases, including HIV. These novel applications are estimated to significantly broaden the market scope and impact.
In terms of indication, the follicular lymphoma (FL) segment is expected to grow at the fastest pace, with a CAGR of 43.2% during the forecast period due to the rising incidence of refractory and high-risk cancer cases.
Based on target antigen, the CD19/CD22 antigen segment, valued at USD 6,258.5 billion in 2024, held the largest market share owing to its established role in treating B-cell malignancies such as diffuse large B-cell lymphoma (DLBCL) and acute lymphoblastic leukemia (ALL).
In the global market, the North America CAR-T cell therapy market held a 47.16% market share in 2024 due to the presence of advanced healthcare infrastructure, significant research and development investments, and a high prevalence of hematologic malignancies.
The Europe CAR-T cell therapy market is expected to witness a CAGR of 33.2% during the forecast period due to increased focus on expanding access to advanced therapies, coupled with the rising prevalence of relapsed or refractory hematologic cancers.
A few of the global key market players are Bluebird Bio; Celgene Corporation; Gilead Sciences; Cellectis; Servier Laboratories; Pfizer Inc.; Merck; Amgen; Intellia Therapeutics; Novartis; Caribou Biosciences; Celyad; Bellicum Pharmaceuticals, Inc.; Noile-Immune Biotech; Nanjing Legend Biotechnology Co., Ltd.; Johnson & Johnson; and Sangamo Therapeutics, Inc.
Polaris Market Research has segmented the CAR-T cell therapy market report on the basis of indication, antigen, and region:
Chapter 1. Introduction
Chapter 2. Executive Summary
Chapter 3. Research Methodology
Chapter 4. CAR-T Cell Therapy Market Insights
Chapter 5. CAR-T Cell Therapy Market Assessment by Indication
Chapter 6. Global CAR-T Cell Therapy Market, by Target Antigen
Chapter 7. CAR-T Cell Therapy Market Assessment by Geography
Chapter 8. Competitive Landscape
Chapter 9. Company Profiles