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がんワクチン市場レポート:タイプ別、技術別、適応症別、エンドユーザー別、地域別、2024~2032年Cancer Vaccines Market Report by Type,, Technology, Indication, End User, and Region 2024-2032 |
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がんワクチン市場レポート:タイプ別、技術別、適応症別、エンドユーザー別、地域別、2024~2032年 |
出版日: 2024年07月01日
発行: IMARC
ページ情報: 英文 148 Pages
納期: 2~3営業日
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世界のがんワクチン市場規模は2023年に68億米ドルに達しました。今後、IMARC Groupは、2024~2032年にかけての成長率(CAGR)は10.2%を示し、2032年には167億米ドルに達すると予測しています。がん罹患率の増加、免疫療法の進歩、政府の取り組みと資金援助、意識向上と教育、急速な技術進歩、戦略的提携とパートナーシップ、医療費の増加などが市場を推進する主要要因です。
がんワクチンは、がん細胞を認識し攻撃するよう身体の免疫系を刺激するよう設計された免疫療法の一種です。これらのワクチンは、免疫系が特定のがん関連抗原を認識するよう訓練することで機能します。この抗原は、がん細胞上に見出され、免疫反応を引き起こす物質です。これらの抗原を体内に導入することで、がんに対する免疫系の自然な防御機構を活性化することを目的としています。がんワクチンには大きく分けて予防(予防)ワクチンと治療ワクチンの2種類があります。予防用がんワクチンは、ヒトパピローマウイルス(HPV)やB型肝炎ウイルス(HBV)などの感染因子によって引き起こされる特定タイプのがんを予防するために使用されます。これらのワクチンは、免疫系を刺激して感染因子に対する免疫反応を産生させ、関連するがんの発症リスクを低下させる。一方、治療用がんワクチンは、既存のがんを治療するために設計されています。がん特異的抗原を導入するか、免疫系がこれらの抗原を認識するのを強化することにより、がん細胞に対する免疫反応を高めることで効果を発揮します。これらのワクチンは、個々の患者の腫瘍細胞に存在する特定の抗原を標的とし、個別化することができます。
世界のがん罹患率の増加は、がんワクチン市場の重要な促進要因です。がんは死亡率の主要な原因であるため、効果的な予防・治療介入に対する需要が高まっています。さらに、がんワクチンを含む免疫療法は、がん治療における有望な治療アプローチとして浮上しています。新規免疫療法戦略の開発と既存の免疫療法の成功が、がんワクチンの需要を押し上げています。この他にも、がん予防と早期発見の重要性に対する一般住民の意識が高まっています。教育キャンペーン、検診プログラム、一般市民への啓蒙活動の増加により、がんワクチンを含む予防対策への需要が高まっています。このほか、同市場では製薬会社、研究機関、学術機関との協力関係も見られます。このようなパートナーシップは、知識、資源、専門知識の交換を促進し、がんワクチンの開発と商業化の加速につながっています。これに伴い、特に新興経済圏における医療支出の増加が、がんワクチンの入手しやすさと値ごろ感を高めています。可処分所得の増加、医療インフラの改善、保険適用範囲の拡大が市場成長に寄与しています。さらに、世界各国の政府がワクチンを含むがん研究開発に積極的に投資していることも、市場の明るい展望を生み出しています。
免疫療法の進歩
免疫療法は、がん細胞を標的として破壊する免疫系の力を活用することで、がん治療に革命をもたらしました。チェックポイント阻害剤や養子細胞療法を含む免疫療法アプローチの成功は、がんワクチンの開発と採用のための強力な基盤を作り上げました。腫瘍抗原に対する特異的な免疫反応を刺激するがんワクチンの能力は、既存の免疫療法戦略をさらに補完するものです。この相乗効果により、併用療法の不可欠な要素としてがんワクチンへの需要が高まり、市場の成長に繋がっています。
政府の取り組みと資金援助
世界各国の政府は、増大するがんの負担に対処する緊急の必要性を認識しています。その結果、各国政府はがんの研究開発、医療インフラへの投資を積極的に行っています。各国政府は、がんワクチンの研究開発に従事する企業に財政支援、助成金、奨励金を提供しています。さらに、規制当局はワクチン開発企業と緊密に協力し、承認プロセスを合理化して市場参入を促進しています。このような支援政策や資金援助イニシアティブは市場の成長に大きく寄与しており、企業の研究、臨床試験、製造能力への投資を可能にしています。
認識と教育の高まり
がんの予防や早期発見に対する一般住民の意識の高まりは、がんワクチンの需要に大きな影響を与えています。公衆衛生キャンペーン、教育プログラム、擁護団体によるイニシアチブは、特定のがんに対する予防措置としてのワクチン接種の重要性を強調しています。HPVワクチンやHBVワクチンなど、がんに関連する感染症の予防ワクチンが成功したことで、がんワクチンの意義がさらに強まった。がん予防や予防接種の利点について人々の知識が深まるにつれ、がんワクチンの需要は増加し、市場成長の原動力になると予想されます。
The global cancer vaccines market size reached US$ 6.8 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 16.7 Billion by 2032, exhibiting a growth rate (CAGR) of 10.2% during 2024-2032. The increasing cancer incidence, advancements in immunotherapy, government initiatives and funding, growing awareness and education, rapid technological advancements, strategic collaborations and partnerships, and increasing healthcare expenditure are some of the major factors propelling the market.
Cancer vaccines are a type of immunotherapy designed to stimulate the body's immune system to recognize and attack cancer cells. These vaccines work by training the immune system to recognize specific cancer-related antigens, substances found on cancer cells that can trigger an immune response. By introducing these antigens into the body, cancer vaccines aim to activate the immune system's natural defense mechanisms against cancer. There are two main types of cancer vaccines, namely preventive (prophylactic) and therapeutic vaccines. Preventive cancer vaccines are used to prevent certain types of cancer caused by infectious agents, such as human papillomavirus (HPV) or hepatitis B virus (HBV). These vaccines stimulate the immune system to produce an immune response against the infectious agent, reducing the risk of developing associated cancers. Therapeutic cancer vaccines, on the other hand, are designed to treat existing cancers. They work by boosting the immune response against cancer cells, either by introducing cancer-specific antigens or by enhancing the immune system's recognition of these antigens. These vaccines can be personalized, targeting specific antigens present in an individual patient's tumor cells.
The rising prevalence of cancer worldwide is a significant driver for the cancer vaccines market. With cancer being a leading cause of mortality, there is a growing demand for effective preventive and therapeutic interventions. Additionally, immunotherapy, including cancer vaccines, has emerged as a promising treatment approach in oncology. The development of novel immunotherapeutic strategies and the success of existing immunotherapies have propelled the demand for cancer vaccines. Other than this, there is a rising awareness among the general population about the importance of cancer prevention and early detection. Increased education campaigns, screening programs, and public awareness initiatives have resulted in a greater demand for preventive measures, including cancer vaccines. Besides this, the market has witnessed collaborations between pharmaceutical companies, research institutes, and academic institutions. These partnerships facilitate the exchange of knowledge, resources, and expertise, leading to accelerated development and commercialization of cancer vaccines. In line with this, the growing healthcare expenditure, particularly in emerging economies, has boosted the accessibility and affordability of cancer vaccines. Rising disposable incomes, improving healthcare infrastructure, and expanding insurance coverage are contributing to market growth. Moreover, governments across the globe are actively investing in cancer research and development, including vaccines, which is creating a positive market outlook.
Advancements in immunotherapy
Immunotherapy has revolutionized cancer treatment by harnessing the power of the immune system to target and destroy cancer cells. The success of immunotherapeutic approaches, including checkpoint inhibitors and adoptive cell therapies, has created a strong foundation for the development and adoption of cancer vaccines. The ability of cancer vaccines to stimulate a specific immune response against tumor antigens further complements existing immunotherapy strategies. This synergy has fueled the demand for cancer vaccines as an integral part of combination therapies, leading to their market growth.
Government initiatives and funding
Governments worldwide have recognized the urgent need to address the growing burden of cancer. As a result, they are actively investing in cancer research, development, and healthcare infrastructure. Governments provide financial support, grants, and incentives to companies engaged in cancer vaccine research and development. Additionally, regulatory agencies are working closely with vaccine developers to streamline approval processes and facilitate market access. These supportive policies and funding initiatives have significantly contributed to the growth of the market, enabling companies to invest in research, clinical trials, and manufacturing capabilities.
Growing awareness and education
Increased awareness among the general population about cancer prevention and early detection has had a profound impact on the demand for cancer vaccines. Public health campaigns, educational programs, and initiatives by advocacy groups have emphasized the importance of vaccinations as a preventive measure against certain cancers. The success of preventive vaccines for infections linked to cancer, such as HPV and HBV vaccines, has further reinforced the significance of cancer vaccines. As people become more knowledgeable about the benefits of cancer prevention and immunization, the demand for cancer vaccines is expected to increase, thus driving market growth.
IMARC Group provides an analysis of the key trends in each segment of the global cancer vaccines market report, along with forecasts at the global, regional and country levels from 2024-2032. Our report has categorized the market based on type, technology, indication and end user.
Preventive Cancer Vaccines
Therapeutic Cancer Vaccines
Preventive cancer vaccines dominate the market
The report has provided a detailed breakup and analysis of the market based on the type. This includes preventive cancer vaccines and therapeutic cancer vaccines. According to the report, preventive cancer vaccines represented the largest segment.
Preventive cancer vaccines have demonstrated significant success in reducing the incidence of specific cancers associated with infectious agents. Vaccines, such as the human papillomavirus (HPV) and hepatitis B virus (HBV), have proven effective in preventing cervical, anal, and certain types of liver cancer, respectively. The efficacy and safety of these vaccines have led to their widespread acceptance. Additionally, these vaccines offer a proactive approach to cancer prevention. They target specific infectious agents known to contribute to the development of certain cancers, thereby providing a direct means of prevention. This approach is especially appealing as it focuses on reducing the risk of developing cancer in the first place, rather than solely relying on early detection or treatment interventions. As public awareness of the benefits of preventive measures increases, individuals and healthcare providers are embracing the use of preventive cancer vaccines, thus contributing to the segment's market dominance. Other than this, preventive cancer vaccines align with global efforts to reduce the burden of cancer. Moreover, governments and healthcare organizations across the world have recognized the value of prevention in combating cancer and have implemented vaccination programs as part of their public health initiatives. These programs target specific populations, such as adolescents for HPV vaccination, to maximize the preventive impact. The extensive implementation of national immunization programs and the inclusion of preventive cancer vaccines in routine vaccination schedules further drive the market segment.
Dendritic Cells Cancer Vaccines
Recombinant Cancer Vaccines
Antigen/Adjuvant Cancer Vaccines
Viral Vector and DNA Cancer Vaccines
Whole-cell Cancer Vaccines
Recombinant cancer vaccines hold the largest share in the market
A detailed breakup and analysis of the market based on technology has also been provided in the report. This includes dendritic cells cancer vaccines, recombinant cancer vaccines, antigen/adjuvant cancer vaccines, viral vector and DNA cancer vaccines, and whole-cell cancer vaccines. According to the report, recombinant cancer vaccines accounted for the largest market share.
Recombinant technology allows for precise and controlled production of cancer vaccines. These vaccines are developed by inserting specific genes or DNA sequences encoding tumor antigens into a vector such as a virus or bacteria. This genetic engineering technique enables researchers to create vaccines that express tumor-specific antigens, effectively targeting cancer cells while minimizing potential side effects. The ability to tailor the vaccine's composition and antigen profile to match the specific characteristics of a patient's tumor makes recombinant cancer vaccines highly customizable and attractive in personalized medicine approaches. Additionally, recombinant vaccines have demonstrated favorable safety and efficacy profiles. The use of recombinant technology allows for the production of vaccines without using live or attenuated pathogens, reducing the risk of adverse events. Additionally, recombinant vaccines can induce a robust immune response by presenting tumor-specific antigens to the immune system in a controlled manner. This targeted immune response enhances the vaccine's efficacy in recognizing and attacking cancer cells. Other than this, this technology offers scalability and cost-effectiveness in vaccine production. The use of recombinant techniques allows for efficient large-scale production of vaccines, thus meeting the demand for widespread vaccination programs.
Cervical Cancer
Prostate Cancer
Others
The report has provided a detailed breakup and analysis of the market based on the indication. This includes cervical cancer, prostate cancer, and others.
Cervical cancer is primarily caused by persistent infection with high-risk types of human papillomavirus (HPV). Vaccines targeting HPV have been successful in preventing cervical cancer. The market for cervical cancer vaccines is driven by the increasing awareness about the role of HPV in cervical cancer development, along with the implementation of national vaccination programs. Vaccines, such as Gardasil and Cervarix, have been developed specifically to prevent HPV infection and subsequent development of cervical cancer. These vaccines have shown remarkable efficacy in preventing HPV infections and reducing the incidence of cervical precancerous lesions. The market segment for cervical cancer vaccines is expected to grow as vaccination rates improve and more countries include HPV vaccination in their immunization programs.
Prostate cancer is the most common cancer among men, and the demand for effective treatment options is high. Vaccines targeting prostate cancer work by stimulating the immune system to recognize and attack prostate cancer cells. Sipuleucel-T (Provenge) is an example of an FDA-approved therapeutic vaccine for advanced prostate cancer. It is designed to boost the patient's immune response against prostate cancer cells. The market for prostate cancer vaccines is driven by the need for innovative treatment options that can improve overall survival and quality of life for patients. Additionally, the rising prevalence of prostate cancer, especially in aging population, contributes to the market growth. Moreover, ongoing research and clinical trials developing new prostate cancer vaccines, is further enhancing the potential of this market segment.
Pediatrics
Adults
A detailed breakup and analysis of the market based on the end user has also been provided in the report. This includes pediatrics and adults.
Pediatric patients, including infants, children, and adolescents, represent a crucial target population for cancer vaccines. Vaccination in pediatrics aims to prevent cancers associated with infectious agents, such as cervical cancer caused by HPV or liver cancer caused by HBV. Vaccinating children and adolescents against these infections can provide long-term protection and reduce the risk of developing associated cancers in adulthood. Government immunization programs and initiatives aimed at promoting pediatric vaccination have been instrumental in driving the market growth. Other than this, the demand for pediatric cancer vaccines is expected to increase with the increasing awareness about the benefits of early prevention and vaccination.
While pediatric vaccination focuses on preventing cancers in early stages of life, adult vaccination targets both preventive and therapeutic purposes. In terms of prevention, adult cancer vaccines primarily aim to protect against infectious agents that contribute to certain cancers, such as HPV-associated cancers, HBV-related liver cancer, and human immunodeficiency virus (HIV)-associated cancers. Additionally, therapeutic vaccines targeting specific antigens expressed by cancer cells are being developed for adult patients. These therapeutic vaccines are designed to stimulate the immune system and enhance the body's ability to recognize and attack cancer cells. The market for adult cancer vaccines is driven by the growing emphasis on preventive healthcare, increasing awareness regarding vaccination benefits in adults, and advancements in therapeutic vaccine research and development.
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
North America exhibits a clear dominance in the market
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America accounted for the largest market share.
North America has a well-developed healthcare infrastructure and advanced research capabilities. The region is home to numerous leading pharmaceutical and biotechnology companies, academic institutions, and research centers specializing in cancer research. This robust ecosystem fosters innovation, enabling the development and commercialization of cutting-edge cancer vaccines. The presence of well-established regulatory frameworks and stringent quality standards further supports the growth of the market in North America. Additionally, there is a high prevalence of cancer in this region, which is accelerating the adoption of effective treatment options, including cancer vaccines. The region experiences a significant burden of various cancers, such as lung, breast, prostate, and colorectal cancers. This increased incidence of cancer creates a substantial market opportunity for cancer vaccines as patients and healthcare providers seek novel therapies for prevention, treatment, and improved patient outcomes. Other than this, North America has a strong emphasis on preventive healthcare and vaccination programs. The region's healthcare systems prioritize disease prevention and public health initiatives, including immunization campaigns. Moreover, vaccination against infectious agents associated with certain cancers, such as HPV and HBV, is actively promoted, leading to a higher uptake of preventive cancer vaccines.
Key players are actively investing in research and development to advance the development of cancer vaccines. They are focused on identifying novel tumor antigens, optimizing vaccine formulations, and exploring innovative delivery systems. Healthcare companies are conducting extensive preclinical and clinical trials to demonstrate the safety, efficacy, and potential of their cancer vaccine candidates. These trials involve collaboration with healthcare institutions and involve a large patient population. By supervising rigorous clinical trials, they are gathering valuable data on the performance of their vaccines, demonstrating their efficacy, and paving the way for regulatory approvals and market entry. Other than this, key players are actively working on expanding market access for cancer vaccines. They are involved in obtaining regulatory approvals in various countries, ensuring manufacturing scalability, and establishing distribution networks. Companies are also focused on educating healthcare providers, patients, and the general public about the benefits of cancer vaccines. Marketing and promotional activities are carried out to create awareness, enhance adoption rates, and drive market growth. Besides this, they continue to invest in their product pipelines and drive innovation in the market by constantly exploring new vaccine candidates, improving existing formulations, and discovering novel approaches to enhance immune responses.
Anixa Biosciences Inc.
Dendreon Pharmaceuticals LLC
Dynavax Technologies Corporation
GSK plc
Merck & Co. Inc.
Moderna Inc.
OSE Immunotherapeutics
Providence Therapeutics
Sanofi S.A.
UbiVac Inc.
Vaccitech PLC
GSK Plc is actively involved in the development of cancer vaccines as part of its commitment to advancing healthcare. In 2022, the company invested £5.5 billion in R&D, 9% AER more than 2021, to enhance its pipeline of vaccines and medicines.
In October 2023, Merck announced that it will be jointly developing and commercializing mRNA-4157/V940 with Moderna. Moderna Inc. has been making recent developments in the cancer vaccines industry by working on mRNA vaccines for cancer treatment.
In 2023, OSE Immunotherapeutics is developing a cancer vaccine called Tedopi, which is the first cancer vaccine to demonstrate clinically meaningful efficacy results, along with a better safety and quality of life profile. It is currently in late-stage clinical development for lung cancer. The Phase 3 results of Tedopi have shown promising outcomes in the field of Immuno-Oncology. Additionally, a new patent has been granted to protect Tedopi as a therapeutic cancer vaccine.