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Gタンパク質共役受容体(GPCR)市場:製品別、アッセイタイプ別、用途別、地域別、2024-2032年G-Protein Coupled Receptors Market by Product, Assay Type, Application, and Region 2024-2032 |
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Gタンパク質共役受容体(GPCR)市場:製品別、アッセイタイプ別、用途別、地域別、2024-2032年 |
出版日: 2024年01月30日
発行: IMARC
ページ情報: 英文 140 Pages
納期: 2~3営業日
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世界のGタンパク質共役受容体(GPCR)市場規模は、2023年に34億米ドルに達しました。今後、IMARC Groupは、2024年から2032年にかけて5.69%の成長率(CAGR)を示し、2032年までに57億米ドルに達すると予測しています。創薬におけるGPCRの採用の増加、がん患者数の増加、広範な研究開発(R&D)活動は、市場を牽引する主な要因の一つです。
Gタンパク質共役受容体(GPCR)は、ヒトゲノムにコードされる最大のタンパク質ファミリーです。GPCRは細胞にシグナルを伝達するシグナル伝達分子であり、細胞外からの刺激を細胞内の反応に変換する上で重要な役割を果たしています。GPCRは細胞膜に存在し、あらゆる生理的プロセスに関与しています。GPCRは細胞表面の受容体で、脂質、糖、光エネルギー、ペプチド、タンパク質の形でメッセージの受信箱のような働きをします。これらの受容体は、炎症性疾患、代謝異常、心疾患、がん、単発性疾患など、様々な疾患の治療に広く用いられています。その結果、GPCRは哺乳類、植物、微生物、無脊椎動物を含むいくつかの生物の細胞膜にも存在しています。
世界中で創薬へのGPCRの採用が増加していることが、市場成長を促進する主な要因の1つです。これに伴い、がん患者数の増加や心血管感染症、呼吸困難などの生活習慣病の増加により、新規医薬品の開発にGPCRが広く利用されていることが、市場の成長を後押ししています。さらに、GPCRは細胞表面に存在するため、さまざまな化学物質や生物学的薬剤によって調節することが可能であり、いくつかの生理的プロセスにおけるGPCRの広範な応用が、もう一つの成長促進要因として作用しています。これとは別に、治療薬の生産能力を向上させるために、自動化と革新的技術を医薬品開発スクリーニング手順と統合することが、市場成長の原動力となっています。さらに、新薬の受容体構造や製剤化を合理化するための計算アプローチの進歩など、効果的な創薬手法の著しい発展が市場成長を後押ししています。さらに、腫瘍学や、浸潤、遊走、血管再形成など、がん生物学のさまざまな側面でGPCRが広く採用されていることも、市場成長に大きな後押しとなっています。このほか、腫瘍の転移や増殖を解読し、効果的な治療法を開発するためのGPCRの利用が増加していることも、市場の成長にプラスの影響を与えています。その他の要因としては、広範な研究開発(R&D)活動、さまざまな自動化の改善、環状アデノシン一リン酸(cAMP)の広範な採用、バイオテクノロジーおよびバイオ医薬品分野における政府のさまざまなイニシアチブの実施などが挙げられ、市場の成長を促進すると予想されています。
The global G-protein coupled receptors (GPCRs) market size reached US$ 3.4 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 5.7 Billion by 2032, exhibiting a growth rate (CAGR) of 5.69% during 2024-2032. The increasing adoption of GPCRs in drug discovery, the rising number of cancer cases, and extensive research and development (R&D) activities represent some of the key factors driving the market.
G-protein-coupled receptors (GPCRs) are the largest protein family encoded by the human genome. They are signal-transducing molecules that transmit signals to cells and play a key role in converting an extracellular stimulus into intracellular responses. They are located in the cell membrane and are responsible for all physiological processes. GPCRs are cell surface receptors that act like an inbox for messages in the form of lipids, sugars, light energy, peptides, and proteins. These receptors are widely used in the treatment of various diseases, such as inflammatory disorders, metabolic imbalances, cardiac disorders, cancer, and monogenic disorders. As a result, GPCRs are also found in the cell membranes of several organisms, including mammals, plants, microorganisms, and invertebrates.
The increasing adoption of GPCRs in drug discovery across the globe is one of the key factors driving the market growth. In line with this, the widespread utilization of GPCRs in the development of novel pharmaceuticals due to the rising number of cancer cases and lifestyle-related diseases, such as cardiovascular infections and respiratory difficulties, are favoring the market growth. Moreover, the extensive application of GPCRs in several physiological processes as they can be modulated by a wide range of chemical or biological agents due to their cell-surface location is acting as another growth-inducing factor. Apart from this, the integration of automation and innovative technologies with drug development screening procedures to improve their capabilities in therapeutic production is providing an impetus to the market growth. Furthermore, significant developments in effective drug discovery methods, such as advancements in the computational approaches to streamline receptor structure and formulation of new drugs, are propelling the market growth. Additionally, the widespread adoption of GPCRs in oncology and various aspects of cancer biology, such as invasion, migration, and vascular remolding, is providing a considerable boost to the market growth. Besides this, the increasing utilization of GPCRs for decoding metastasis and growth of tumors and developing effective lines of treatment is positively influencing the market growth. Other factors, including extensive research and development (R&D) activities, various automation improvements, the widespread adoption of cyclic Adenosine Monophosphate (cAMP), and the implementation of various government initiatives in the biotechnology and biopharmaceutical sector are anticipated to drive the market growth.
IMARC Group provides an analysis of the key trends in each segment of the global G-protein coupled receptors (GPCRs) market, along with forecasts at the global, regional, and country level from 2024-2032. Our report has categorized the market based on product, assay type, and application.
Cell Lines
Detection Kits
Cell Culture Reagents
Ligands
The report has provided a detailed breakup and analysis of the G-protein coupled receptors (GPCRs) market based on the product. This includes cell lines, detection kits, cell culture reagents and ligands. According to the report, cell lines represented the largest segment.
cAMP Functional Assays
Calcium Functional Assays
B-Arrestin Functional Assays
Radioligand Binding and GTPγS Functional Assays
Internalization Assays
Trafficking Assays
Others
The report has provided a detailed breakup and analysis of the G-protein coupled receptors (GPCRs) market based on the assay type. This includes cAMP functional, calcium functional, B-Arrestin functional, radioligand binding and GTPγS functional, internalization, and trafficking assays. According to the report, cAMP functional assays represented the largest segment.
Cancer Research
CNS Research
Metabolic Research
Cardiovascular Research
Inflammation Research
Respiratory Research
Others
The report has provided a detailed breakup and analysis of the G-protein coupled receptors (GPCRs) market based on the application. This includes cancer, CNS, metabolic, cardiovascular, inflammation, respiratory research, and others. According to the report, cancer research represented the largest segment.
North America
United States
Canada
Asia Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
The report has also provided a comprehensive analysis of all the major regional markets that include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and Middle East and Africa. According to the report, North America was the largest market for G-protein coupled receptors (GPCRs). Some of the factors driving the North America G-protein coupled receptors (GPCRs) market included rising number of cancer cases, extensive research and development (R&D) activities, and various automation improvements.
The report has also provided a comprehensive analysis of the competitive landscape in the global G-protein coupled receptors (GPCRs) market. Detailed profiles of all major companies have also been provided. Some of the companies covered include Abcam plc, Becton Dickinson and Company, Enzo Biochem Inc., Eurofins DiscoverX Products LLC, HD Biosciences Co. Ltd. (WuXi AppTec), Merck KGaA, Molecular Devices LLC (Danaher Corporation), PerkinElmer Inc., Promega Corporation, Thermo Fisher Scientific Inc., etc.