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遺伝子治療市場:世界の産業動向、シェア、規模、成長機会、2023-2028年予測Gene Therapy Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2023-2028 |
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遺伝子治療市場:世界の産業動向、シェア、規模、成長機会、2023-2028年予測 |
出版日: 2023年05月29日
発行: IMARC
ページ情報: 英文 142 Pages
納期: 2~3営業日
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世界の遺伝子治療市場規模は、2022年に44億米ドルに達しました。今後、IMARC Groupは、2023年から2028年の間に15.39%の成長率(CAGR)を示し、2028年までに109億米ドルに達すると予測しています。遺伝性疾患や後天性疾患の増加、病院、診療所、介護施設の建設増加、オピオイドに代わる安全で中毒性のない新しい遺伝子治療の人気の高まりなどが、市場を牽引する主な要因の一部です。
慢性疾患の増加による市場成長への影響
大衆の間で様々な慢性疾患の有病率が高まっていることは、遺伝子治療市場の成長を促進する重要な要因の1つです。また、不健康な生活習慣の採用による心血管合併症、糖尿病、甲状腺炎、肥満などの慢性疾患の発生が、市場の成長に寄与しています。さらに、大衆の間でがんの症例が増加しており、効果的な腫瘍学的治療に対する需要の高まりとともに、良好な市場展望を提供しています。さらに、過度の喫煙習慣による慢性肺疾患の増加も、遺伝子治療市場の成長を後押ししています。
市場構造、主要企業による市場シェア、プレイヤーのポジショニング、主要成功戦略、競合ダッシュボード、企業評価象限などの競合分析については、本レポートで取り上げています。また、すべての主要企業の詳細なプロファイルが提供されています。遺伝子治療市場の構造は、多数の世界的および地域的なプレーヤーが存在するため、適度に断片化されています。高い資本投資が必要であること、政府の政策が厳しいこと、製品の差別化率が低いことなどから、市場への新規参入の量は中程度です。
遺伝子治療とは?
遺伝子治療とは、治療目的で変異した遺伝子の発現を変化させたり、生体細胞の生物学的特性を変化させたりすることで、病気の進行を防ぐ技術です。ウイルスベクター、細菌ベクター、プラスミド・デオキシリボ核酸(DNA)、ヒト遺伝子編集技術、患者由来の細胞性遺伝子治療など、さまざまな製品から構成されています。遺伝性疾患の原因となっている変異を修復するために、健康な遺伝子を個人のゲノムに導入するものです。生体外遺伝子治療、生体内遺伝子治療、in situ遺伝子治療など、さまざまな治療法からなります。遺伝子治療は、遺伝子の抑制、遺伝子の増強、そして最終的には病気の原因となる細胞の死滅によって機能します。薬では防げない特定の病気を治すことができ、病気の症状を永久に取り除くことができる可能性があります。また、がん、糖尿病、血友病、嚢胞性線維症、心臓病、後天性免疫不全症候群(AIDS)など、さまざまな病気に対する体の抵抗力を向上させることができます。また、遺伝子治療は他の薬のように何度も服用する必要がないため、世界中でその需要が高まっています。
コロナウイルスの発生は、遺伝子治療市場を大きく混乱させ、さまざまなバイオ医薬品企業の業績に影響を与えました。一部の遺伝子治療企業は、その複雑な製造・送達システムや資金調達モデルにより、膨大な数の合併症に直面しました。治療の製造と提供、研究開発と臨床開発、商業運営はパンデミックによって悪影響を受け、その結果、遺伝子治療市場の成長が阻害されました。また、遺伝子治療製品の製造・開発を支えるサプライチェーンは、管理された複雑な環境を必要とします。サプライチェーンは、施錠や道路を介した移動に課された制限によって深刻な影響を受けました。さらに、COVID-19の発生により、いくつかの企業が業務の遅延や完全停止を報告しました。
現在、遺伝子治療は、生命を脅かすさまざまな難病の治療に有効であることから、その需要が高まっており、市場にプラスの影響を与える主要な要因の一つとなっています。これに加えて、大衆の間で遺伝性疾患や後天性疾患の有病率が上昇していることも、市場の成長を後押ししています。また、患者に質の高いヘルスケアサービスを提供するために、世界中で病院、診療所、介護施設の建設が増加していることも、市場の成長に寄与しています。これとは別に、腰痛や稀な神経障害性疼痛障害など、幅広い慢性疼痛疾患の治療において、オピオイドに代わるより安全で非中毒性のものを提供する新しい遺伝子治療の人気が高まっており、市場の好ましい展望を提供しています。
The global gene therapy market size reached US$ 4.4 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 10.9 Billion by 2028, exhibiting a growth rate (CAGR) of 15.39% during 2023-2028. The growing prevalence of inherited diseases and acquired disorders; increasing construction of hospitals, clinics, and nursing homes; and rising popularity of new gene therapy that offers a safer, non-addictive alternative to opioids represent some of the key factors driving the market.
Rising Occurrence of Chronic Diseases Augmenting Market Growth
The increasing prevalence of various chronic diseases among the masses represents one of the key factors propelling the growth of the gene therapy market. Besides this, the occurrence of various chronic diseases, such as cardiovascular complications, diabetes, thyroiditis, and obesity, due to the adoption of unhealthy lifestyle patterns is contributing to the growth of the market. Moreover, rising cases of cancer among the masses, along with the growing demand for effective oncology treatment, is offering a favorable market outlook. Furthermore, the increasing occurrence of chronic lung diseases due to excessive smoking habits is bolstering the growth of the gene therapy market.
Competitive analysis such as market structure, market share by key players, player positioning, top winning strategies, competitive dashboard, and company evaluation quadrant has been covered in the report. Also, detailed profiles of all major companies have been provided. The structure of the gene therapy market is moderately fragmented due to the presence of a large number of global and regional players. The volume of new entrants in the market is moderate due to the requirement for high capital investments, stringent government policies, and the rate of product differentiation is low.
What is Gene Therapy?
Gene therapy is a technique for preventing disease progression by modifying the expression of mutated genes or altering the biological properties of living cells for therapeutic use. It comprises different products, such as viral vectors, bacterial vectors, plasmid deoxyribonucleic acid (DNA), human gene-editing technology, and patient-derived cellular gene therapy. It involves the introduction of a healthy gene into the genome of an individual to repair a mutation that is causing a genetic disorder. It consists of various therapies, such as ex vivo, in vivo, and in situ gene therapy. Gene therapy functions via gene inhibition, gene augmentation, and ultimately killing the disease-causing cells. It can cure certain diseases which no medications can prevent and has the potential to get rid of disease symptoms permanently. It also improves the ability of the body to fight against a wide variety of diseases, such as cancer, diabetes, hemophilia, cystic fibrosis, heart disease, and acquired immunodeficiency syndrome (AIDS). Furthermore, as gene therapy does not require multiple doses like other medications, its demand is increasing around the world.
The outbreak of coronavirus severely disrupted the gene therapy market and affected the performance of various biopharmaceutical companies. Some gene therapy companies faced an immense number of complications due to their complicated manufacturing and delivery systems and funding models. The manufacture and delivery of treatment, research and clinical development, and commercial operations were negatively impacted by the pandemic, which resulted in a disruption in the growth of the gene therapy market. In addition, the supply chains that support the manufacturing and development of gene therapy products require controlled and complex settings. The supply chain was severely impacted by lockdowns and restrictions imposed on movement via roads. Furthermore, several companies reported delays or complete halts in operations due to the outbreak of COVID-19.
At present, the growing demand for gene therapy, as it is effective in curing various critical and life-threatening diseases, represents one of the primary factors influencing the market positively. Besides this, the rising prevalence of inherited diseases and acquired disorders among the masses is propelling the growth of the market. In addition, the increasing construction of hospitals, clinics, and nursing homes around the world to provide quality healthcare services to patients is contributing to the growth of the market. Apart from this, the rising popularity of new gene therapy that offers a safer and non-addictive alternative to opioids in treating a broad range of chronic pain conditions, such as lower back pain and rare neuropathic pain disorders, is offering a favorable market outlook.
IMARC Group provides an analysis of the key trends in each sub-segment of the global gene therapy market report, along with forecasts at the global, regional and country level from 2023-2028. Our report has categorized the market based on gene type, vector type, delivery method and application.
Antigen
Cytokine
Tumor Suppressor
Suicide Gene
Deficiency
Growth Factors
Receptors
Others
The report has provided a detailed breakup and analysis of the gene therapy market based on the gene type. This includes antigen, cytokine, tumor suppressor, suicide gene, deficiency, growth factors, receptors, and others.
Viral Vector
Adenoviruses
Lentiviruses
Retroviruses
Adeno-Associated Virus
Herpes Simplex Virus
Poxvirus
Vaccinia Virus
Others
Non-Viral Techniques
Naked and Plasmid Vectors
Gene Gun
Electroporation
Lipofection
Others
A detailed breakup and analysis of the gene therapy market based on the vector type has also been provided in the report. This includes viral vector (adenoviruses, lentiviruses, retroviruses, adeno-associated virus, herpes simplex virus, poxvirus, vaccinia virus, and others) and non-viral techniques (naked and plasmid vectors, gene gun, electroporation, lipofection, and others). According to the report, viral vector (adenoviruses, lentiviruses, retroviruses, adeno-associated virus, herpes simplex virus, poxvirus, vaccinia virus, and others) accounted for the largest market share as it is highly efficient in mitigating the impacts of infectious diseases and viruses. In addition, the rising utilization of viral vectors as they are easy to handle and modify is propelling the growth of the respective segment.
In-Vivo Gene Therapy
Ex-Vivo Gene Therapy
A detailed breakup and analysis of the gene therapy market based on the delivery method has also been provided in the report. This includes in-vivo gene therapy and ex-vivo gene therapy.
Oncological Disorders
Rare Diseases
Cardiovascular Diseases
Neurological Disorders
Infectious Disease
Others
A detailed breakup and analysis of the gene therapy market based on the application has also been provided in the report. This includes oncological disorders, rare diseases, cardiovascular diseases, neurological disorders, infectious disease, and others. According to the report, oncological disorders accounted for the largest market share due to increasing occurrence of cancer among the masses. Apart from this, the rising employment of gene therapy in cancer treatment as it provides remarkable efficacy is bolstering the growth of the market.
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America (the United States and Canada) was the largest market for gene therapy. Some of the factors driving the North America gene therapy market included the rising awareness about the benefits of gene therapy in treating various chronic diseases and the increasing expenditure in research and development (R&D) activities to develop effective gene therapies is propelling the market growth. In addition, the growing construction of various healthcare facilities to provide quality treatment to patients is propelling the growth of the market.
Abeona Therapeutics Inc.
Adaptimmune Therapeutics plc
Adverum Biotechnologies Inc.
Amgen Inc.
Astellas Pharma Inc.
Biogen Inc.
Bluebird Bio Inc.
Mustang Bio Inc. (Fortress Biotech Inc.)
Novartis AG
Orchard Therapeutics plc
UniQure N.V.
Voyager Therapeutics Inc.
Please note that this only represents a partial list of companies, and the complete list has been provided in the report.
Key Questions Answered in This Report
1. What was the size of the global gene therapy market in 2022?
2. What is the expected growth rate of the global gene therapy market during 2023-2028?
3. What are the key factors driving the global gene therapy market?
4. What has been the impact of COVID-19 on the global gene therapy market?
5. What is the breakup of the global gene therapy market based on the vector type?
6. What is the breakup of the global gene therapy market based on the application?
7. What are the key regions in the global gene therapy market?
8. Who are the key players/companies in the global gene therapy market?