Product Code: GVR-2-68038-495-6
Downstream Processing Market Growth & Trends:
The global downstream processing market size is expected to reach USD 94.8 billion by 2030, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 15.0% from 2022 to 2030. The capacity requirements during the development of biologic drugs have changed over the past few years, wherein the demand for manufacturing high-volume products has shifted to developing small-volume, high-potency products. This creates new avenues for single-use technologies. A rise in the utilization of downstream processing techniques for the development of COVID-19 vaccines is a significant factor driving the market. The adoption of small-scale, single-use systems for process development and downstream processing is already high.
Thus, evolutionary changes are expected in the area of single-use technologies for manufacturing small-volume, highly-potent drugs. The development of novel film chemistries, closed systems, automation in clinical-scale single-use systems, and smart sensors are some noteworthy advancements in the field. A rise in applications of downstream processing for the production of biopharmaceuticals is expected to bring growth opportunities to the market. This has also led to an increase in strategic deals and development in the market. For instance, in February 2021, Evozyne, LLC collaborated with a leading rare disorders drug manufacturer for the production and marketing of novel biopharmaceuticals for immune modulation.
Key players are investing in the bioprocessing of vaccines and therapies for COVID-19 to increase their market share. For instance, in May 2022, Lonza and ALSA Ventures are partnering to provide biotech firms with development and manufacturing services. In May 2022, Lonza added Titanium Dioxide-free white hard gelatin capsules to its Capsugel Capsule Line. The new capsule includes an alternative opacifying technology that provides a good masking solution as well as enhanced light protection for the fill formulation. In December 2021, Repligen bought Newton, New Jersey-based BioFlex Solutions. The purchase adds to and enhances Repligen's single-use fluid management product line, as well as simplifies its supply chain. The integration of BioFlex Solutions strengthens its system offering by further integrating components and assemblies.
Downstream Processing Market Report Highlights:
- Chromatography systems accounted for the largest revenue share in 2021 owing to the high adoption of chromatography for biopharmaceutical purification
- The advent of single-use chromatography systems that bring an 80.0% reduction of the use of water and chemicals for buffer has further increased the adoption of chromatography for downstream processing of bio-therapeutics
- Filters are anticipated to grow at a lucrative rate over the forecast period. Efforts undertaken by the key players to develop intelligent membranes for purification & separation is fuelling the market growth
- Purification by chromatography accounted for the largest revenue share as it can be employed across all steps of a downstream process. The technique is also crucial in bioprocessing to obtain pure biologics
- Antibiotic production dominated the market in 2021 owing to the wide use of antibiotics for the treatment of a variety of clinical disorders including infectious diseases and cancer
- A rise in occurrences of antibiotic resistance also propels the industrial-scale development of novel antibiotic candidates
- North America dominated the global market in 2021 owing to the presence of large in-house biopharmaceutical manufacturing facilities
- Asia Pacific will register the fastest CAGR from 2022 to 2030 due to a rise in contract development services in emerging economies
Table Of Contents
Chapter 1 Executive Summary
- 1.1 Market Outlook
- 1.2 Segment Outlook
- 1.3 Competition Milieu
- 1.4 Market Snapshot
Chapter 2 Research Methodology
- 2.1 Information Procurement
- 2.1.1 Purchased database
- 2.1.2 GVR's Internal Database
- 2.1.3 Secondary sources
- 2.2 Third Party Perspective
- 2.3 Sample size for the study on Downstream Processing Market:
- 2.3.1 Manufacturers-
- 2.3.2 List of Secondary Data Sources
- 2.4 Information or Data Analysis
- 2.5 Market Formulation & Validation
- 2.6 Objectives
- 2.6.1 Objective 1
- 2.6.2 Objective 2
Chapter 3 Market Variables, Trends & Scope
- 3.1 Market Lineage Outlook
- 3.1.1 Parent market outlook
- 3.1.2 Related/ancillary market outlook
- 3.1.2.1 Single-use bioprocessing market
- 3.1.2.2 Biopharmaceuticals market
- 3.2 Market Trends & Outlook
- 3.3 Market Segmentation & Scope
- 3.4 Market Dynamics
- 3.4.1 Market driver analysis
- 3.4.1.1 Commercial success of biopharmaceuticals boosts demand for innovation in bioprocessing
- 3.4.1.2 Rising adoption of single-use technology in bioprocessing
- 3.4.1.2.1 Environmental advantage
- 3.4.1.2.2 Operating and construction cost advantage
- 3.4.1.2.3 Flexibility advantage
- 3.4.1.2.4 Time advantage
- 3.4.1.3 Expansion of bioprocessing capacity
- 3.4.2 Market restraint analysis
- 3.4.2.1 High cost
- 3.4.2.2 Dearth of skilled professionals
- 3.5 Penetration & Growth Prospect Mapping For Product, 2021
- 3.6 Downstream Processing Market Analysis Tools
- 3.6.1 Global downstream processing market-SWOT analysis, by factor (political & legal, economic and technological)
- 3.6.2 Industry Analysis - Porter's
- 3.6.3 Major Deals & Strategic Alliances Analysis
- 3.6.3.1 Collaborations
- 3.6.3.2 Agreements
- 3.6.3.3 Partnerships
- 3.6.4 Market Entry Strategies
Chapter 4 Global Downstream Processing Market Categorization: Product Estimates & Trend Analysis
- 4.1 Global Downstream Processing Market: Product Type Movement Analysis
- 4.2 Chromatography Systems
- 4.2.1 Global chromatography systems market, 2018 - 2030 (USD Million)
- 4.3 Filters
- 4.3.1 Global filters market, 2018 - 2030 (USD Million)
- 4.4 Evaporators
- 4.4.1 Global evaporators market, 2018 - 2030 (USD Million)
- 4.5 Centrifuges
- 4.5.1 Global centrifuges market, 2018 - 2030 (USD Million)
- 4.6 Dryers
- 4.6.1 Global dryers' market, 2018 - 2030 (USD Million)
- 4.7 Other downstream processing products
- 4.7.1 Global other downstream processing products market, 2018 - 2030 (USD Million)
Chapter 5 Global Downstream Processing Market Categorization: Technique Estimates & Trend Analysis
- 5.1 Global Downstream Processing Market: Technique Movement Analysis
- 5.2 Cell Disruption
- 5.2.1 Global cell disruption market, 2018 - 2030 (USD Million)
- 5.3 Solid-Liquid Separation
- 5.3.1 Global solid-liquid separation market, 2018 - 2030 (USD Million)
- 5.3.2 Filtration
- 5.3.2.1 Global filtration market, 2018 - 2030 (USD Million)
- 5.3.3 Centrifugation
- 5.3.3.1 Global centrifugation market, 2018 - 2030 (USD Million)
- 5.4 Concentration
- 5.4.1 Global concentration market, 2018 - 2030 (USD Million)
- 5.4.2 Evaporation
- 5.4.2.1 Global evaporation market, 2018 - 2030 (USD Million)
- 5.4.3 Membrane filtration
- 5.4.3.1 Global membrane filtration market, 2018 - 2030 (USD Million)
- 5.5 Purification by Chromatography
- 5.5.1 Global purification by chromatography market, 2018 - 2030 (USD Million)
- 5.6 Formulation
- 5.6.1 Global formulation market, 2018 - 2030 (USD Million)
Chapter 6 Global Downstream Processing Market Categorization: Application Estimates & Trend Analysis
- 6.1 Global Downstream Processing Market: Application Movement Analysis
- 6.2 Antibiotic Production
- 6.2.1 Global downstream processing market for antibiotic production, 2018 - 2030 (USD Million)
- 6.3 Hormone Production
- 6.3.1 Global downstream processing market for hormone production, 2018 - 2030 (USD Million)
- 6.4 Antibodies Production
- 6.4.1 Global downstream processing market for antibodies production, 2018 - 2030 (USD Million)
- 6.5 Enzyme Production
- 6.5.1 Global downstream processing market for enzyme production, 2018 - 2030 (USD Million)
- 6.6 Vaccine Production
- 6.6.1 Global downstream processing market for vaccine production, 2018 - 2030 (USD Million)
Chapter 7 Global Downstream Processing Market Categorization: Regional Estimates & Trend Analysis, by Product, Technique, & Application
- 7.1 Global Downstream Processing Market Share By Regional, 2021 & 2030
- 7.2 North America
- 7.2.1 North America downstream processing market, 2018 - 2030 (USD Million)
- 7.2.2 U.S.
- 7.2.2.1 U.S. downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.2.2.2 U.S. downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.2.2.3 U.S. downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.2.3 Canada
- 7.2.3.1 Canada downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.2.3.2 Canada downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.2.3.3 Canada downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.3 Europe
- 7.3.1 Europe downstream processing market, 2018 - 2030 (USD Million)
- 7.3.2 U.K.
- 7.3.2.1 U.K. downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.3.2.2 U.K. downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.3.2.3 U.K. downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.3.3 Germany
- 7.3.3.1 Germany downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.3.3.2 Germany downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.3.3.3 Germany downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.3.4 France
- 7.3.4.1 France downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.3.4.2 France downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.3.4.3 France downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.3.5 Italy
- 7.3.5.1 Italy downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.3.5.2 Italy downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.3.5.3 Italy downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.3.6 Spain
- 7.3.6.1 Spain downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.3.6.2 Spain downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.3.6.3 Spain downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.4 Asia Pacific
- 7.4.1 Asia Pacific downstream processing market, 2018 - 2030 (USD Million)
- 7.4.2 Japan
- 7.4.2.1 Japan downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.4.2.2 Japan downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.4.2.3 Japan downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.4.3 China
- 7.4.3.1 China downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.4.3.2 China downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.4.3.3 China downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.4.4 India
- 7.4.4.1 India downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.4.4.2 India downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.4.4.3 India downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.4.5 South Korea
- 7.4.5.1 South Korea downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.4.5.2 South Korea downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.4.5.3 South Korea downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.4.6 Australia
- 7.4.6.1 Australia downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.4.6.2 Australia downstream processing market, by technique, 2017 -2028 (USD Million)
- 7.4.6.3 Australia downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.5 Latin America
- 7.5.1 Latin America downstream processing market,
- 7.5.2 Brazil
- 7.5.2.1 Brazil downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.5.2.2 Brazil downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.5.2.3 Brazil downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.5.3 Mexico
- 7.5.3.1 Mexico downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.5.3.2 Mexico downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.5.3.3 Mexico downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.6 Middle East & Africa (MEA)
- 7.6.1 MEA downstream processing market, 2018 - 2030 (USD Million)
- 7.6.2 South Africa
- 7.6.2.1 South Africa downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.6.2.2 South Africa downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.6.2.3 South Africa downstream processing market, by application, 2018 - 2030 (USD Million)
- 7.6.3 UAE
- 7.6.3.1 UAE downstream processing market, by product, 2018 - 2030 (USD Million)
- 7.6.3.2 UAE downstream processing market, by technique, 2018 - 2030 (USD Million)
- 7.6.3.3 UAE downstream processing market, by application, 2018 - 2030 (USD Million)
Chapter 8 Global Downstream Processing Market: Competitive Landscape
- 8.1 Strategy Framework
- 8.2 Market Participant Categorization
- 8.3 Company Profiles
- 8.3.1 Thermo Fisher Scientific, Inc.
- 8.3.1.1 Company overview
- 8.3.1.2 Financial performance
- 8.3.1.3 Product benchmarking
- 8.3.1.4 Strategic initiatives
- 8.3.2 General Electric Company
- 8.3.2.1 Company overview
- 8.3.2.2 Financial performance
- 8.3.2.3 Product benchmarking
- 8.3.2.4 Strategic initiatives
- 8.3.3 Sartorius AG
- 8.3.3.1 Company overview
- 8.3.3.2 Financial performance
- 8.3.3.3 Product benchmarking
- 8.3.3.4 Strategic initiatives
- 8.3.4 Merck KGaA
- 8.3.4.1 Company overview
- 8.3.4.2 Financial performance
- 8.3.4.3 Product benchmarking
- 8.3.4.4 Strategic initiatives
- 8.3.5 Danaher
- 8.3.5.1 Company overview
- 8.3.5.2 Financial performance
- 8.3.5.3 Product benchmarking
- 8.3.5.4 Strategic initiatives
- 8.3.6 3M Company
- 8.3.6.1 Company overview
- 8.3.6.2 Financial performance
- 8.3.6.3 Product benchmarking
- 8.3.7 Repligen Corporation
- 8.3.7.1 Company overview
- 8.3.7.2 Financial performance
- 8.3.7.3 Product benchmarking
- 8.3.7.4 Strategic initiatives
- 8.3.8 C. H. Boehringer Sohn AG & Co. KG
- 8.3.8.1 Company overview
- 8.3.8.2 Financial performance
- 8.3.8.3 Product benchmarking
- 8.3.8.4 Strategic initiatives
- 8.3.9 Lonza Group Ltd
- 8.3.9.1 Company overview
- 8.3.9.2 Financial performance
- 8.3.9.3 Product benchmarking
- 8.3.9.4 Strategic initiatives
- 8.3.10 Eppendorf AG
- 8.3.10.1 Company overview
- 8.3.10.2 Financial performance
- 8.3.10.3 Product benchmarking
- 8.3.10.4 Strategic initiatives
- 8.3.11 Corning Incorporated
- 8.3.11.1 Company overview
- 8.3.11.2 Financial performance
- 8.3.11.3 Product benchmarking
- 8.3.12 Asahi Kasei Corporation
- 8.3.12.1 Company overview
- 8.3.12.2 Financial performance
- 8.3.12.3 Product benchmarking
- 8.3.12.4 Strategic initiatives
- 8.3.13 Dover Corporation
- 8.3.13.1 Company overview
- 8.3.13.2 Financial performance
- 8.3.13.3 Product benchmarking
- 8.3.13.4 Strategic initiatives
- 8.3.14 Fenner PLC
- 8.3.14.1 Company overview
- 8.3.14.2 Financial performance
- 8.3.14.3 Product benchmarking
- 8.3.15 Kaneka Corporation
- 8.3.15.1 Company overview
- 8.3.15.2 Financial performance
- 8.3.15.3 Product benchmarking
- 8.3.15.4 Strategic initiatives