Product Code: A02527
Downstream processing refers to the recovery and purification of biosynthetic products, particularly pharmaceuticals, from natural sources such as animal or plant tissue or fermentation broth. It is an essential step in the manufacture of pharmaceuticals such as antibiotics, hormones (e.g., insulin and human growth hormone), antibodies (e.g., infliximab and abciximab) and vaccines; antibodies and enzymes used in diagnostics; industrial enzymes; and natural fragrance and flavor compounds. Downstream processing is usually considered a specialized field in biochemical engineering.
The key factors that drive the growth of the market are increase in demand for biopharmaceuticals as downstream processing plays a key role in providing pure biopharmaceutical products. In addition, rise in R&D expenditure for biopharmaceutical products majorly drive the growth of the market. Furthermore, rise in adoption of single-use systems, low risk of product cross contamination and cost-effectiveness are the key factors anticipating the growth of market in upcoming years. In addition, single-use system in downstream processing is highly efficient and cost-effective, which attract pharmaceutical manufacturers to adopt disposable bioprocessing products drive the growth of the market in upcoming years. However, dearth and shortage of skilled bioprocess engineers is expected to restrain the market growth in upcoming years. Moreover, untapped markets such as China and India, offer profitable opportunities to expand this market.
The downstream processing market is segmented on the basis of technique, product, system application, end user, and region. By technique, it is categorized into purification, separation, and clarification/concentration. Depending on product, it is classified into chromatography columns and resins, filters, membrane absorbers, and other products. By system, it is bifurcated into single use system and re-usable system. By application, it is divided into monoclonal antibody production, vaccine production, insulin production, immunoglobulin production, erythropoietin production, and other applications. By end user, it is categorized into biopharmaceutical manufacturers, and contract manufacturing organizations (CMOs).
Region wise, the market is analyzed across North America (the U.S., Canada, and Mexico), Europe (Germany, France, the UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea, and rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and rest of LAMEA).
North America accounted for the largest market share in the downstream processing market in 2020 and is expected to retain its dominance throughout the forecast period. This is primarily attributed to increase in R&D activities for biopharmaceuticals, considerable investments made by the market players and increase in government support are fueling the growth of the market in this region.
The major companies profiled in this report include, 3M Company, Sartorius Stedim Biotech S.A, Danaher Corporation, Thermo Fisher Scientific Inc., Merck & Co., Inc., Boehringer Ingelheim, Lonza Group AG, Eppendorf AG, Finesse Solutions, Inc. and Repligen Corporation
Key Benefits For Stakeholders
- This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of theDownstream Processing Market Size analysis from 2020 to 2030 to identify the prevailing downstream processing market opportunities.
- The market research is offered along with information related to key drivers, restraints, and opportunities.
- Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
- In-depth analysis of the downstream processing market segmentation assists to determine the prevailing market opportunities.
- Major countries in each region are mapped according to their revenue contribution to the global market.
- Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
- The report includes the analysis of the regional as well as global downstream processing market trends, key players, market segments, application areas, and market growth strategies.
Key Market Segments
By Technology
- Purification
- Separation
- Clarification/Concentration
By Product
- Chromatography Columns and Resins
- Filters
- Membrane Adsorbers
- Other Products
By System
- Single Use System
- Re Usable System
By Application
- Monoclonal Antibody Production
- Vaccine Production
- Insulin Production
- Immunoglobulin Production
- Erythropoietin Production
- Other Applications
By End User
- Biopharmaceutical Manufacturers
- Contract Manufacturing Organizations (CMOs)
By Region
- North America
- Europe
- Germany
- France
- U.K.
- Italy
- Spain
- Rest of Europe
- Asia-Pacific
- Japan
- China
- India
- Australia
- South Korea
- Rest Of Asia Pacific
- LAMEA
- Brazil
- Saudi Arabia
- South Africa
- Rest of LAMEA
- Key Market Players
- Thermo Fisher Scientific Inc.
- Sartorius Stedim Biotech S.A
- Bio Rad Laboratories, Inc
- 3M Company
- Lonza Group AG
- Eppendorf AG
- Marathon Petroleum Corporation
- Merck KGaA.
- Religen Inc
- Agilent Technologies Inc.
TABLE OF CONTENTS
CHAPTER 1:INTRODUCTION
- 1.1.Report description
- 1.2.Key market segments
- 1.3.Key benefits to the stakeholders
- 1.4.Research Methodology
- 1.4.1.Secondary research
- 1.4.2.Primary research
- 1.4.3.Analyst tools and models
CHAPTER 2:EXECUTIVE SUMMARY
- 2.1.Key findings of the study
- 2.2.CXO Perspective
CHAPTER 3:MARKET OVERVIEW
- 3.1.Market definition and scope
- 3.2.Key findings
- 3.2.1.Top investment pockets
- 3.3.Porter's five forces analysis
- 3.4.Top player positioning
- 3.5.Market dynamics
- 3.5.1.Drivers
- 3.5.2.Restraints
- 3.5.3.Opportunities
- 3.6.COVID-19 Impact Analysis on the market
CHAPTER 4: DOWNSTREAM PROCESSING MARKET, BY TECHNOLOGY
- 4.1 Overview
- 4.1.1 Market size and forecast
- 4.2 Purification
- 4.2.1 Key market trends, growth factors and opportunities
- 4.2.2 Market size and forecast, by region
- 4.2.3 Market analysis by country
- 4.3 Separation
- 4.3.1 Key market trends, growth factors and opportunities
- 4.3.2 Market size and forecast, by region
- 4.3.3 Market analysis by country
- 4.4 Clarification/Concentration
- 4.4.1 Key market trends, growth factors and opportunities
- 4.4.2 Market size and forecast, by region
- 4.4.3 Market analysis by country
CHAPTER 5: DOWNSTREAM PROCESSING MARKET, BY PRODUCT
- 5.1 Overview
- 5.1.1 Market size and forecast
- 5.2 Chromatography Columns and Resins
- 5.2.1 Key market trends, growth factors and opportunities
- 5.2.2 Market size and forecast, by region
- 5.2.3 Market analysis by country
- 5.3 Filters
- 5.3.1 Key market trends, growth factors and opportunities
- 5.3.2 Market size and forecast, by region
- 5.3.3 Market analysis by country
- 5.4 Membrane Adsorbers
- 5.4.1 Key market trends, growth factors and opportunities
- 5.4.2 Market size and forecast, by region
- 5.4.3 Market analysis by country
- 5.5 Other Products
- 5.5.1 Key market trends, growth factors and opportunities
- 5.5.2 Market size and forecast, by region
- 5.5.3 Market analysis by country
CHAPTER 6: DOWNSTREAM PROCESSING MARKET, BY SYSTEM
- 6.1 Overview
- 6.1.1 Market size and forecast
- 6.2 Single Use System
- 6.2.1 Key market trends, growth factors and opportunities
- 6.2.2 Market size and forecast, by region
- 6.2.3 Market analysis by country
- 6.3 Re Usable System
- 6.3.1 Key market trends, growth factors and opportunities
- 6.3.2 Market size and forecast, by region
- 6.3.3 Market analysis by country
CHAPTER 7: DOWNSTREAM PROCESSING MARKET, BY APPLICATION
- 7.1 Overview
- 7.1.1 Market size and forecast
- 7.2 Monoclonal Antibody Production
- 7.2.1 Key market trends, growth factors and opportunities
- 7.2.2 Market size and forecast, by region
- 7.2.3 Market analysis by country
- 7.3 Vaccine Production
- 7.3.1 Key market trends, growth factors and opportunities
- 7.3.2 Market size and forecast, by region
- 7.3.3 Market analysis by country
- 7.4 Insulin Production
- 7.4.1 Key market trends, growth factors and opportunities
- 7.4.2 Market size and forecast, by region
- 7.4.3 Market analysis by country
- 7.5 Immunoglobulin Production
- 7.5.1 Key market trends, growth factors and opportunities
- 7.5.2 Market size and forecast, by region
- 7.5.3 Market analysis by country
- 7.6 Erythropoietin Production
- 7.6.1 Key market trends, growth factors and opportunities
- 7.6.2 Market size and forecast, by region
- 7.6.3 Market analysis by country
- 7.7 Other Applications
- 7.7.1 Key market trends, growth factors and opportunities
- 7.7.2 Market size and forecast, by region
- 7.7.3 Market analysis by country
CHAPTER 8: DOWNSTREAM PROCESSING MARKET, BY END USER
- 8.1 Overview
- 8.1.1 Market size and forecast
- 8.2 Biopharmaceutical Manufacturers
- 8.2.1 Key market trends, growth factors and opportunities
- 8.2.2 Market size and forecast, by region
- 8.2.3 Market analysis by country
- 8.3 Contract Manufacturing Organizations (CMOs)
- 8.3.1 Key market trends, growth factors and opportunities
- 8.3.2 Market size and forecast, by region
- 8.3.3 Market analysis by country
CHAPTER 9: DOWNSTREAM PROCESSING MARKET, BY REGION
- 9.1 Overview
- 9.1.1 Market size and forecast
- 9.2 North America
- 9.2.1 Key trends and opportunities
- 9.2.2 North America Market size and forecast, by Technology
- 9.2.3 North America Market size and forecast, by Product
- 9.2.4 North America Market size and forecast, by System
- 9.2.5 North America Market size and forecast, by Application
- 9.2.6 North America Market size and forecast, by End User
- 9.2.7 North America Market size and forecast, by country
- 9.2.7.1 U.S.
- 9.2.7.1.1 Market size and forecast, by Technology
- 9.2.7.1.2 Market size and forecast, by Product
- 9.2.7.1.3 Market size and forecast, by System
- 9.2.7.1.4 Market size and forecast, by Application
- 9.2.7.1.5 Market size and forecast, by End User
- 9.2.7.2 Canada
- 9.2.7.2.1 Market size and forecast, by Technology
- 9.2.7.2.2 Market size and forecast, by Product
- 9.2.7.2.3 Market size and forecast, by System
- 9.2.7.2.4 Market size and forecast, by Application
- 9.2.7.2.5 Market size and forecast, by End User
- 9.2.7.3 Mexico
- 9.2.7.3.1 Market size and forecast, by Technology
- 9.2.7.3.2 Market size and forecast, by Product
- 9.2.7.3.3 Market size and forecast, by System
- 9.2.7.3.4 Market size and forecast, by Application
- 9.2.7.3.5 Market size and forecast, by End User
- 9.3 Europe
- 9.3.1 Key trends and opportunities
- 9.3.2 Europe Market size and forecast, by Technology
- 9.3.3 Europe Market size and forecast, by Product
- 9.3.4 Europe Market size and forecast, by System
- 9.3.5 Europe Market size and forecast, by Application
- 9.3.6 Europe Market size and forecast, by End User
- 9.3.7 Europe Market size and forecast, by country
- 9.3.7.1 Germany
- 9.3.7.1.1 Market size and forecast, by Technology
- 9.3.7.1.2 Market size and forecast, by Product
- 9.3.7.1.3 Market size and forecast, by System
- 9.3.7.1.4 Market size and forecast, by Application
- 9.3.7.1.5 Market size and forecast, by End User
- 9.3.7.2 France
- 9.3.7.2.1 Market size and forecast, by Technology
- 9.3.7.2.2 Market size and forecast, by Product
- 9.3.7.2.3 Market size and forecast, by System
- 9.3.7.2.4 Market size and forecast, by Application
- 9.3.7.2.5 Market size and forecast, by End User
- 9.3.7.3 U.K.
- 9.3.7.3.1 Market size and forecast, by Technology
- 9.3.7.3.2 Market size and forecast, by Product
- 9.3.7.3.3 Market size and forecast, by System
- 9.3.7.3.4 Market size and forecast, by Application
- 9.3.7.3.5 Market size and forecast, by End User
- 9.3.7.4 Italy
- 9.3.7.4.1 Market size and forecast, by Technology
- 9.3.7.4.2 Market size and forecast, by Product
- 9.3.7.4.3 Market size and forecast, by System
- 9.3.7.4.4 Market size and forecast, by Application
- 9.3.7.4.5 Market size and forecast, by End User
- 9.3.7.5 Spain
- 9.3.7.5.1 Market size and forecast, by Technology
- 9.3.7.5.2 Market size and forecast, by Product
- 9.3.7.5.3 Market size and forecast, by System
- 9.3.7.5.4 Market size and forecast, by Application
- 9.3.7.5.5 Market size and forecast, by End User
- 9.3.7.6 Rest of Europe
- 9.3.7.6.1 Market size and forecast, by Technology
- 9.3.7.6.2 Market size and forecast, by Product
- 9.3.7.6.3 Market size and forecast, by System
- 9.3.7.6.4 Market size and forecast, by Application
- 9.3.7.6.5 Market size and forecast, by End User
- 9.4 Asia-Pacific
- 9.4.1 Key trends and opportunities
- 9.4.2 Asia-Pacific Market size and forecast, by Technology
- 9.4.3 Asia-Pacific Market size and forecast, by Product
- 9.4.4 Asia-Pacific Market size and forecast, by System
- 9.4.5 Asia-Pacific Market size and forecast, by Application
- 9.4.6 Asia-Pacific Market size and forecast, by End User
- 9.4.7 Asia-Pacific Market size and forecast, by country
- 9.4.7.1 Japan
- 9.4.7.1.1 Market size and forecast, by Technology
- 9.4.7.1.2 Market size and forecast, by Product
- 9.4.7.1.3 Market size and forecast, by System
- 9.4.7.1.4 Market size and forecast, by Application
- 9.4.7.1.5 Market size and forecast, by End User
- 9.4.7.2 China
- 9.4.7.2.1 Market size and forecast, by Technology
- 9.4.7.2.2 Market size and forecast, by Product
- 9.4.7.2.3 Market size and forecast, by System
- 9.4.7.2.4 Market size and forecast, by Application
- 9.4.7.2.5 Market size and forecast, by End User
- 9.4.7.3 India
- 9.4.7.3.1 Market size and forecast, by Technology
- 9.4.7.3.2 Market size and forecast, by Product
- 9.4.7.3.3 Market size and forecast, by System
- 9.4.7.3.4 Market size and forecast, by Application
- 9.4.7.3.5 Market size and forecast, by End User
- 9.4.7.4 Australia
- 9.4.7.4.1 Market size and forecast, by Technology
- 9.4.7.4.2 Market size and forecast, by Product
- 9.4.7.4.3 Market size and forecast, by System
- 9.4.7.4.4 Market size and forecast, by Application
- 9.4.7.4.5 Market size and forecast, by End User
- 9.4.7.5 South Korea
- 9.4.7.5.1 Market size and forecast, by Technology
- 9.4.7.5.2 Market size and forecast, by Product
- 9.4.7.5.3 Market size and forecast, by System
- 9.4.7.5.4 Market size and forecast, by Application
- 9.4.7.5.5 Market size and forecast, by End User
- 9.4.7.6 Rest Of Asia Pacific
- 9.4.7.6.1 Market size and forecast, by Technology
- 9.4.7.6.2 Market size and forecast, by Product
- 9.4.7.6.3 Market size and forecast, by System
- 9.4.7.6.4 Market size and forecast, by Application
- 9.4.7.6.5 Market size and forecast, by End User
- 9.5 LAMEA
- 9.5.1 Key trends and opportunities
- 9.5.2 LAMEA Market size and forecast, by Technology
- 9.5.3 LAMEA Market size and forecast, by Product
- 9.5.4 LAMEA Market size and forecast, by System
- 9.5.5 LAMEA Market size and forecast, by Application
- 9.5.6 LAMEA Market size and forecast, by End User
- 9.5.7 LAMEA Market size and forecast, by country
- 9.5.7.1 Brazil
- 9.5.7.1.1 Market size and forecast, by Technology
- 9.5.7.1.2 Market size and forecast, by Product
- 9.5.7.1.3 Market size and forecast, by System
- 9.5.7.1.4 Market size and forecast, by Application
- 9.5.7.1.5 Market size and forecast, by End User
- 9.5.7.2 Saudi Arabia
- 9.5.7.2.1 Market size and forecast, by Technology
- 9.5.7.2.2 Market size and forecast, by Product
- 9.5.7.2.3 Market size and forecast, by System
- 9.5.7.2.4 Market size and forecast, by Application
- 9.5.7.2.5 Market size and forecast, by End User
- 9.5.7.3 South Africa
- 9.5.7.3.1 Market size and forecast, by Technology
- 9.5.7.3.2 Market size and forecast, by Product
- 9.5.7.3.3 Market size and forecast, by System
- 9.5.7.3.4 Market size and forecast, by Application
- 9.5.7.3.5 Market size and forecast, by End User
- 9.5.7.4 Rest of LAMEA
- 9.5.7.4.1 Market size and forecast, by Technology
- 9.5.7.4.2 Market size and forecast, by Product
- 9.5.7.4.3 Market size and forecast, by System
- 9.5.7.4.4 Market size and forecast, by Application
- 9.5.7.4.5 Market size and forecast, by End User
CHAPTER 10: COMPANY LANDSCAPE
- 10.1. Introduction
- 10.2. Top winning strategies
- 10.3. Product Mapping of Top 10 Player
- 10.4. Competitive Dashboard
- 10.5. Competitive Heatmap
- 10.6. Key developments
CHAPTER 11: COMPANY PROFILES
- 11.1 Thermo Fisher Scientific Inc.
- 11.1.1 Company overview
- 11.1.2 Company snapshot
- 11.1.3 Operating business segments
- 11.1.4 Product portfolio
- 11.1.5 Business performance
- 11.1.6 Key strategic moves and developments
- 11.2 Sartorius Stedim Biotech S.A
- 11.2.1 Company overview
- 11.2.2 Company snapshot
- 11.2.3 Operating business segments
- 11.2.4 Product portfolio
- 11.2.5 Business performance
- 11.2.6 Key strategic moves and developments
- 11.3 Bio Rad Laboratories, Inc
- 11.3.1 Company overview
- 11.3.2 Company snapshot
- 11.3.3 Operating business segments
- 11.3.4 Product portfolio
- 11.3.5 Business performance
- 11.3.6 Key strategic moves and developments
- 11.4 3M Company
- 11.4.1 Company overview
- 11.4.2 Company snapshot
- 11.4.3 Operating business segments
- 11.4.4 Product portfolio
- 11.4.5 Business performance
- 11.4.6 Key strategic moves and developments
- 11.5 Lonza Group AG
- 11.5.1 Company overview
- 11.5.2 Company snapshot
- 11.5.3 Operating business segments
- 11.5.4 Product portfolio
- 11.5.5 Business performance
- 11.5.6 Key strategic moves and developments
- 11.6 Eppendorf AG
- 11.6.1 Company overview
- 11.6.2 Company snapshot
- 11.6.3 Operating business segments
- 11.6.4 Product portfolio
- 11.6.5 Business performance
- 11.6.6 Key strategic moves and developments
- 11.7 Marathon Petroleum Corporation
- 11.7.1 Company overview
- 11.7.2 Company snapshot
- 11.7.3 Operating business segments
- 11.7.4 Product portfolio
- 11.7.5 Business performance
- 11.7.6 Key strategic moves and developments
- 11.8 Merck KGaA.
- 11.8.1 Company overview
- 11.8.2 Company snapshot
- 11.8.3 Operating business segments
- 11.8.4 Product portfolio
- 11.8.5 Business performance
- 11.8.6 Key strategic moves and developments
- 11.9 Religen Inc
- 11.9.1 Company overview
- 11.9.2 Company snapshot
- 11.9.3 Operating business segments
- 11.9.4 Product portfolio
- 11.9.5 Business performance
- 11.9.6 Key strategic moves and developments
- 11.10 Agilent Technologies Inc.
- 11.10.1 Company overview
- 11.10.2 Company snapshot
- 11.10.3 Operating business segments
- 11.10.4 Product portfolio
- 11.10.5 Business performance
- 11.10.6 Key strategic moves and developments