タバパドン市場：市場規模、予測、新たな洞察-2032年

Cerevel Therapeuticsは、早期および後期のパーキンソン病治療薬としてタバパドンを開発しています。タバパドンは、経口生物学的利用可能な1日1回投与の部分作動薬として合理的に設計されており、ドパミンD1/D5受容体サブタイプを選択的に標的とし、有意義な運動活性と好ましい安全性プロファイルのバランスをとります。

本薬は、早期パーキンソン病の単剤療法としても、後期パーキンソン病の補助療法としても使用できる可能性があります。Cerevelは現在、TEMPO-1、TEMPO-2、TEMPO-3と呼ばれるタバパドンのパーキンソン病における単剤療法（早期）および併用療法（後期）の第III相臨床試験を実施しています。また、TEMPO-4と呼ばれる非盲検延長試験も実施しています。Cerevel はTEMPO-3試験のデータを2024年半ばに、TEMPO-1とTEMPO-2のデータを2024年後半に期待しています。

タバパドンは、直接運動経路を特異的に活性化し、日中の鎮静（傾眠）、衝動制御の低下、幻覚を含む精神病症状のリスクなど、ドーパミンを非選択的に刺激する薬剤に典型的な副作用を最小限に抑えながら、運動効果を促進する可能性があります。本薬はまた、フルアゴニストによって引き起こされる長時間の受容体過剰興奮と脱感作を抑え、ジスキネジアや「オフ」時間の悪化を招きながら、運動効果を最大化するレベルでD1/D5受容体サブタイプを活性化するよう設計されています。

今後数年間で、パーキンソン病の市場シナリオは、世界中の広範な調査と医療支出の増加により変化します。各社は、病状を治療/改善するための新たなアプローチに焦点を当てた治療法を開発し、課題を評価し、タバパドンの優位性に影響を与える可能性のある機会を模索しています。パーキンソン病に対する他の新興製品がタバパドンと厳しい市場競争を繰り広げることが予想され、近い将来に後発の新興治療薬が発売されれば、市場に大きな影響を与えるとみられています。

当レポートでは、主要7ヶ国におけるパーキンソン病治療薬のタバパドン市場について調査し、市場の概要とともに、競合情勢、2032年までの市場規模予測、および国別市場分析などを提供しています。

目次

第1章 レポートのイントロダクション

第2章 パーキンソン病におけるタバパドンの概要

• 製品の詳細
• 臨床開発
  • 臨床研究
  • 臨床試験情報
  • 安全性と有効性
• その他の開発活動
• 製品プロファイル

第3章 競合情勢（上市済み治療法）

第4章 競合情勢（後期段階の新興治療法）

第5章 タバパドン市場評価

• パーキンソン病におけるタバパドンの市場見通し
• 主要7ヶ国分析
  • 主要7ヶ国のパーキンソン病治療薬タバパドンの市場規模
• 国別市場分析
  • 米国
  • ドイツ
  • 英国

第6章 SWOT分析

第7章 アナリストの見解

第8章 付録

第9章 DelveInsightのサービス内容

第10章 免責事項

第11章 DelveInsightについて

第12章 レポート購入オプション

List of Tables

• Table 1: Tavapadon, Clinical Trial Description, 2023
• Table 2: Tavapadon, General Description
• Table 3: Competitive Landscape (Marketed Therapies)
• Table 4: Competitive Landscape (Late-stage Emerging Therapies)
• Table 5: Tavapadon Market Size in the 7MM, in USD million (2019-2032)
• Table 6: Tavapadon Market Size in the US, in USD million (2019-2032)
• Table 7: Tavapadon Market Size in Germany, in USD million (2019-2032)
• Table 8: Tavapadon Market Size in France, in USD million (2019-2032)
• Table 9: Tavapadon Market Size in Italy, in USD million (2019-2032)
• Table 10: Tavapadon Market Size in Spain, in USD million (2019-2032)
• Table 11: Tavapadon Market Size in the UK, in USD million (2019-2032)
• Table 12: Tavapadon Market Size in Japan, in USD million (2019-2032)

List of Figures

• Figure 1: Tavapadon Market Size in the 7MM, USD million (2019-2032)
• Figure 2: Tavapadon Market Size in the United States, USD million (2019-2032)
• Figure 3: Tavapadon Market Size in Germany, USD million (2019-2032)
• Figure 4: Tavapadon Market Size in France, USD million (2019-2032)
• Figure 5: Tavapadon Market Size in Italy, USD million (2019-2032)
• Figure 6: Tavapadon Market Size in Spain, USD million (2019-2032)
• Figure 7: Tavapadon Market Size in the United Kingdom, USD million (2019-2032)
• Figure 8: Tavapadon Market Size in Japan, USD million (2019-2032)

"Tavapadon Market Size, Forecast, and Emerging Insight - 2032" report provides comprehensive insights about tavapadon for Parkinson's disease in the seven major markets. A detailed picture of the tavapadon for Parkinson's Disease in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the tavapadon for Parkinson's Disease. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the tavapadon market forecast analysis for Parkinson's disease in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in Parkinson's disease.

Drug Summary:

Cerevel Therapeutics is developing tavapadon to treat both early and late-stage Parkinson's disease. Tavapadon was rationally designed as an orally-bioavailable, once-daily partial agonist that selectively targets dopamine D1/D5 receptor subtypes to balance meaningful motor activity with a favourable safety profile.

It has the potential to be used as both, a monotherapy for early-stage Parkinson's disease and as adjunctive therapy for late-stage Parkinson's disease. Cerevel is currently conducting Phase III trials of tavapadon, known as TEMPO-1, TEMPO-2, and TEMPO-3, as monotherapy (early-stage) and adjunctive (late-stage) in Parkinson's disease. It is also conducting an open-label extension trial, known as TEMPO-4. Cerevel expects data from the TEMPO-3 trial in mid-year 2024 and TEMPO-1 and TEMPO-2 in the second half of 2024.

Mechanism of Action

Tavapadon differentially activates the direct motor pathway, potentially driving motor benefit while minimizing side effects typical of drugs that non-selectively stimulate dopamine, such as daytime sedation, or somnolence, compromised impulse control, and risk of psychotic symptoms including hallucinations. The drug is also designed to activate the D1/D5 receptor subtypes at levels that maximize motor benefit while reducing the prolonged receptor overexcitation and desensitization caused by full agonists, leading to dyskinesias and exacerbation of "off" time.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the tavapadon description, mechanism of action, dosage and administration, research and development activities in Parkinson's disease.
• Elaborated details on tavapadon regulatory milestones and other development activities have been provided in this report.
• The report also highlights the tavapadon research and development activities in Parkinson's disease across the United States, Europe and Japan.
• The report also covers the patents information with expiry timeline around tavapadon.
• The report contains forecasted sales of tavapadon for Parkinson's disease till 2032.
• Comprehensive coverage of the late-stage emerging therapies for Parkinson's disease.
• The report also features the SWOT analysis with analyst views for tavapadon in Parkinson's disease.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

Tavapadon Analytical Perspective by DelveInsight

• In-depth Tavapadon Market Assessment

This report provides a detailed market assessment of tavapadon for Parkinson's disease in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2025 to 2032.

• Tavapadon Clinical Assessment

The report provides the clinical trials information of tavapadon for Parkinson's disease covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for Parkinson's disease is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence tavapadon dominance.
• Other emerging products for Parkinson's disease are expected to give tough market competition to tavapadon and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of tavapadon in Parkinson's disease.
• Our in-depth analysis of the forecasted sales data of tavapadon from 2025 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the tavapadon in Parkinson's disease.

Key Questions:

• What is the product type, route of administration and mechanism of action of tavapadon?
• What is the clinical trial status of the study related to tavapadon in Parkinson's disease and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the tavapadon development?
• What are the key designations that have been granted to tavapadon for Parkinson's disease?
• What is the forecasted market scenario of tavapadon for Parkinson's disease?
• What are the forecasted sales of tavapadon in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how are these giving competition to tavapadon for Parkinson's disease?
• Which are the late-stage emerging therapies under development for the treatment of Parkinson's disease?

Table of Contents

1. Report Introduction

2. Tavapadon Overview in Parkinson's disease

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and Efficacy
• 2.3. Other Developmental Activities
• 2.4. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. Tavapadon Market Assessment

• 5.1. Market Outlook of Tavapadon in Parkinson's disease
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of Tavapadon in the 7MM for Parkinson's disease
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of Tavapadon in the United States for Parkinson's disease
  • 5.3.2. Market Size of Tavapadon in Germany for Parkinson's disease
  • 5.3.3. Market Size of Tavapadon in France for Parkinson's disease
  • 5.3.4. Market Size of Tavapadon in Italy for Parkinson's disease
  • 5.3.5. Market Size of Tavapadon in Spain for Parkinson's disease
  • 5.3.6. Market Size of Tavapadon in the United Kingdom for Parkinson's disease
  • 5.3.7. Market Size of Tavapadon in Japan for Parkinson's disease

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options