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市場調査レポート
商品コード
1226597
VVZ-149新薬の考察と市場予測(2032年)VVZ-149 Emerging Drug Insight and Market Forecast - 2032 |
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VVZ-149新薬の考察と市場予測(2032年) |
出版日: 受注後更新
発行: DelveInsight
ページ情報: 英文 30 Pages
納期: 2~10営業日
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当レポートでは、米国のVVZ-149新薬市場について調査分析し、作用機序、用法と用量、研究開発活動についての考察や、市場予測などを提供しています。
"VVZ-149 Emerging Drug Insight and Market Forecast - 2032" report provides comprehensive insights about VVZ-149 for Postoperative Pain in the United States. A detailed picture of the VVZ-149 for Postoperative Pain in the United States for the study period 2019-2032 is provided in this report along with a detailed description of the VVZ-149 for Postoperative Pain. The report provides insight about mechanism of action, dosage and administration, as well as research and development activity including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the VVZ-149 market forecast, analysis for Postoperative Pain in the United States, descriptive analysis such as SWOT, analyst views, comprehensive overview of market competitors, and brief about other emerging therapies in Postoperative Pain.
Vivozon, Inc. is developing VVZ-149, a drug with a new mechanism-based nonnarcotic and non-NSAID analgesic. VVZ-149 is currently being evaluated in clinical trials (Korea and the US) in an IV infusion setting to treat postoperative pain following laparoscopic gastrectomy or laparoscopic colorectomy and lumbar radiculopathy (Sciatica). The company is preparing a comprehensive data package to initiate the GLP toxicology studies of the oral VVZ-149. According to the company, VVZ-149 demonstrated a robust (comparable to morphine) pain-suppressing efficacy in a panel of in vivo models (postoperative, formalin-induced or neuropathic pain model). The compound has also shown an anti-itching effect in the serotonin-induced itching model. These in vivo efficacies are attributed to the synergistic or additive dual antagonistic activity of VVZ-149 against GlyT2 and 5HT2A, which are key receptors for the transmission of the pain signal in the spinal dorsal horn area and/or peripheral sensory neurons.
Two clinical Phase I studies of VVZ-149 injections were successfully completed in 2014 to secure the safety and tolerability of the drug. The Phase IIa studies to evaluate the analgesic efficacy and safety of VVZ-149 Injections in patients with postoperative pain following the surgical operations were successfully completed in Korea (laparoscopic gastrectomy in early gastric cancer patients; Severance Hospital, Seoul) and the US (laparoscopic colorectal surgery; Brigham Women's Hospital, Boston, MA Massachusetts's General Hospital, Boston, MA and Beth Israel Deaconess Medical Center, MA). An additional clinical Phase Ib/IIa study for neuropathic pain in patients with chronic central and peripheral pain is currently underway in the US. Vivozon is preparing the comprehensive data package to initiate the GLP toxicology studies of oral VVZ-149, showing excellent oral bioavailability for the long-term administration to treat chronic pain, including neuropathic pain.
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
This report provides a detailed market assessment of VVZ-149 in Postoperative Pain in the United States. This segment of the report provides forecasted sales data from 2023 to 2032.
The report provides the clinical trials information of VVZ-149 in Postoperative Pain covering trial interventions, trial conditions, trial status, start and completion dates.