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市場調査レポート
商品コード
1400507
細胞・遺伝子治療CDMOの世界市場(2024年版):タイプ別、用途別、適応症別、地域別、国別の分析、市場考察、予測(2024年~2029年)Global Cell and Gene Therapy CDMO Market (2024 Edition): Analysis By Type (Cell Therapy, Gene Therapy, Gene-modified Cell Therapies), Application (Clinical, Pre-clinical), Indication, By Region, By Country: Market Insights and Forecast (2024-2029) |
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細胞・遺伝子治療CDMOの世界市場(2024年版):タイプ別、用途別、適応症別、地域別、国別の分析、市場考察、予測(2024年~2029年) |
出版日: 2024年01月01日
発行: Azoth Analytics
ページ情報: 英文 260 Pages
納期: 即納可能
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世界の細胞・遺伝子治療CDMOの市場規模は、2022年の25億4,000万米ドルから2024年~2029年の予測期間にCAGRで30.75%の成長が予測されています。市場は、細胞・遺伝子治療の継続的な進歩に後押しされ、健全な成長と需要の高まりを示しています。治療領域の拡大と良好な規制環境により、市場はさまざまな疾患に対する画期的な治療法の開発と商業化において極めて重要な役割を果たしており、持続的な拡大が見込まれています。市場は、業界の各社からの多額の投資に牽引され、驚異的な成長が見込まれています。
世界の細胞・遺伝子治療のパイプラインは拡大しており、がん、希少疾患、遺伝性疾患などの幅広い治療領域をカバーしています。より多くの治療法が臨床試験を経て商業化に向けて進むにつれて、製造、プロセス開発、スケールアップに向けたCDMOサービスへの需要が高まっています。
世界の細胞・遺伝子治療向けのCDMO組織は拡大しており、これが世界の細胞・遺伝子治療の全体的な拡大を推進する主な要因の1つとなっています。先進の細胞・遺伝子治療に対する世界の需要の増加に伴い、CDMOはバイオテクノロジー企業や製薬企業の変化する需要に対応するため、さまざまな場所に生産施設を積極的に設立しています。昨今、CDMOは医薬品の製造に欠かせない存在となっています。過去10年間で、CDMOはよりダイナミックなM&Aの状況により、その存在感を増してきました。地域市場と国際市場の両方にサービスを提供し、現在600を超える開発・製造受託機関(CDMO)が活動しています。CDMOは「大手製薬企業」と小規模発明者の両方が製品を早期に上市できるよう、特定の専門知識を提供します。
生物製剤の台頭は、新しい生物製剤製造施設に多額の投資を行っているCDMOの数からも見て取れます。これらの企業には、Boehringer Ingelheim(投資額8億2,700万米ドル)、Samsung Biologics(投資額17億米ドル)、Lonza(投資額9億3500万米ドル)、Fujifilm Diosynth Biotechnologies(投資額20億米ドル)などがあります。
さらに、世界に拡大することで、CDMOは地域の規制ニーズに対応し、カスタマイズされた製造ソリューションを提供し、そのサービスを必要とする顧客にとってのアクセシビリティを向上させることができます。CDMOは重要な世界市場に存在することで、より適応性が高く、迅速なソリューションを提供することができます。これにより、遺伝子・細胞治療の開発と世界の商業化を加速することができます。
市場の成長を抑制する顕著な要因の1つは、ウイルスベクターの高い製造コストです。治療用遺伝子を標的細胞に運ぶ担体として、ウイルスベクターは遺伝子・細胞治療の開発に不可欠です。ウイルスベクターの製造は複雑な手順で、特殊な技術、厳格な品質管理基準、特殊な設備が頻繁に必要とされます。
現在、遺伝子治療に使用されているウイルスベクターは5種類あります。AAVの市場シェアがもっとも高く、次いでレンチウイルス、アデノウイルス、単純ヘルペスウイルス、レトロウイルスとなっています。Roland Berger Insightsによると、単回投与分のベクター製造コストは、バッチあたり300万~700万米ドルが予測されることから、100万~200万米ドルになる可能性があります。そのため、ウイルスベクターの高い製造コストが、細胞・遺伝子治療が広く商業化され、利用しやすくなる妨げとなっています。
当レポートでは、世界の細胞・遺伝子治療CDMO市場について調査し、市場規模と予測、地域とセグメントの分析、主な動向と機会などの情報を提供しています。
List of Tables
Table A1: Global Impact of Macro Economic Factors, By Region
Table A2: OXB's Internal Cell and Gene Therapy Pipeline
Table A3: Clinical AAV Gene Therapies for Genetic Neurological Disorders
Table A4: FDA NME Approvals, 2019-2022
Table A5: Drugs by Therapy Area
Table A6: Approved Gene, Cell, and RNA Therapies Globally, for Clinical Use
Table A7: Pipeline Therapies by Category
Table A8: Approved Gene, Cell, and RNA Therapies Globally, for Clinical Use
Table A9: Number of Therapies from Pre-clinical through Pre-registration
Table A10: Therapies in the Clinic (excludes preclinical development)
Table A11: Cell and Gene Therapy Landscape, by Region
Table A12: Landscape of Key Cell and Gene Therapy Service Providers
Table A13: United States Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A14: United States Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A15: United States Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A16: United States Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A17: United States Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A18: United States Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A19: Canada Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A20: Canada Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A21: Canada Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A22: Canada Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A23: Canada Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A24: Canada Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A25: Rest of Americas Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A26: Rest of Americas Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A27: Rest of Americas Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A28: Rest of Americas Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A29: Rest of Americas Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A30: Rest of Americas Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A31: United Kingdom Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A32: United Kingdom Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A33: United Kingdom Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A34: United Kingdom Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A35: United Kingdom Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A36: United Kingdom Elevated Work Platform (MEWP) Market, By Indication, By Value, 2023-2029 (USD Million)
Table A37: Germany Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A38: Germany Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A39: Germany Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A40: Germany Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A41: Germany Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A42: Germany Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A43: France Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A44: France Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A45: France Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A46: France Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A47: France Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A48: France Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A49: Italy Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A50: Italy Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A51: Italy Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A52: Italy Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A53: Italy Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A54: Italy Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A55: Rest of Europe Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A56: Rest of Europe Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A57: Rest of Europe Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A58: Rest of Europe Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A59: Rest of Europe Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A60: Rest of Europe Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A61: China Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A62: China Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A63: China Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A64: China Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A65: China Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A66: China Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A67: Japan Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A68: Japan Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A69: Japan Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A70: Japan Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A71: Japan Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A72: Japan Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A73: South Korea Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A74: South Korea Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A75: South Korea Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A76: South Korea Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A77: South Korea Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A78: South Korea Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A79: India Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A80: India Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A81: India Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A82: India Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A83: India Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A84: India Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A85: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Type, By Value, 2019-2022 (USD Million)
Table A86: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Type, By Value, 2023-2029 (USD Million)
Table A87: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Application, By Value, 2019-2022 (USD Million)
Table A88: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Application, By Value, 2023-2029 (USD Million)
Table A89: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Indication, By Value, 2019-2022 (USD Million)
Table A90: Rest of Asia Pacific Cell and Gene Therapy CDMO Market, By Indication, By Value, 2023-2029 (USD Million)
Table A91: Oxford Biomedica Financials, 2020-2022
Table A92: Lonza Group AG Financials, 2020-2022
Table A93: Catalent, Inc. Financials, 2020-2022
Table A94: Samsung Biologics Financials, 2020-2022
Table A95: WuXi Biologics Financials, 2020-2022
Table A96: Pfizer CentreOne Financials, 2020-2022
Table A97: Danaher Corporation Financials, 2020-2022
Table A98: Thermo Fisher Scientific Inc. Financials, 2020-2022
Table A99: Charles River Laboratories International, Inc. Financials, 2020-2022
Table A100: Novartis AG Financials, 2020-2022
Azoth Analytics has released a research report titled "Global Cell and Gene Therapy CDMO Market (2024 Edition)" which provides a complete analysis of the Global Cell and Gene Therapy CDMO Market industry in terms of market segmentation by Type (Cell Therapy, Gene Therapy, Gene-modified Cell Therapies), Application (Clinical, Pre-clinical), Indication (Oncology Diseases, Infectious Diseases, Neurological Disorder, Others) for the historical period of 2019-2022, estimates of 2023 and the forecast for 2024-2029.
The Global Cell and Gene Therapy CDMO market valued at USD 2.54 billion in 2022 is expected to grow at a CAGR of 30.75% during the forecast period of 2024-2029. The global Cell and Gene Therapy CDMO market has been experiencing robust growth and escalating demand, propelled by continuous advancements in cell and gene therapies. With a broadening scope of therapeutic areas and a favourable regulatory environment, the global Cell and Gene Therapy CDMO market is poised for sustained expansion as it plays a pivotal role in the development and commercialization of ground-breaking therapies for various diseases. The global Cell and Gene Therapy CDMO market is expected to grow at an extraordinary rate driven by significant investments from industry players.
The global pipeline of cell and gene therapies has been expanding, covering a wide range of therapeutic areas, including oncology, rare diseases, and genetic disorders. As more therapies advance through clinical trials and toward commercialization, the demand for CDMO services for manufacturing, process development, and scale-up increases.
Global CDMO organisations for cell and gene therapy are expanding, and this is one of the main factors propelling the global Cell and Gene Therapy's overall expansion. With the increasing global demand for advanced cell and gene therapies, CDMOs are proactively setting up production facilities in various locations to meet the changing demands of biotechnology and pharmaceutical companies. These days, CDMOs are essential to the manufacturing of pharmaceuticals. Over the past ten years, CDMOs have grown in prominence due to a more dynamic mergers and acquisition landscape. Serving both local and international markets, there are currently over 600 active Contract Development and Manufacturing Organizations (CDMOs). CDMOs provide specific expertise that helps both "Big Pharma" and smaller inventors to launch products sooner.
The rise of biologics is seen by the number of CDMOs making significant investments in brand-new biomanufacturing facilities. These companies include Boehringer Ingelheim (USD827M investment), Samsung Biologics (USD1.7B investment), Lonza (USD935M expansion), and Fujifilm Diosynth Biotechnologies (USD2B investment).
Additionally, by expanding globally, CDMOs can meet regional regulatory needs, provide customised manufacturing solutions, and improve accessibility for customers who need their services. CDMOs can provide more adaptable and responsive solutions by being present in important worldwide markets. This helps to speed up the development and global commercialization of gene and cell therapies.
One prominent factor restraining the growth of the global Cell and Gene Therapy CDMO market is the high cost of producing viral vectors. As carriers of therapeutic genes into target cells, viral vectors are essential to the development of gene and cell therapies. Viral vector production is a complex procedure that frequently involves specialized techniques, stringent quality control standards, and specialized facilities.
There are now five viral vectors in use for gene therapy. AAV have the biggest market share, followed by lentiviruses, adenoviruses, herpes simplex viruses and retroviruses. The vector manufacturing cost for a single dose might be as high as USD 1-2 million, given the expected price of USD 3-7 million per batch, according to Roland Berger Insights. Therefore, the high cost of producing viral vectors hampers cell and gene therapies from being widely commercialised and made accessible, which limits their uptake and hinders the expansion of the Cell and Gene CDMO market.