ダウンストリームプロセス市場の市場規模、シェア、成長分析：技術別、製品別、用途別、エンドユーザー別、地域別 - 産業予測 2025～2032年

ダウンストリームプロセス市場規模は2023年に364億米ドルと評価され、予測期間（2025-2032年）のCAGRは16.4%で、2024年の423億7,000万米ドルから2032年には1,427億8,000万米ドルに成長する見通しです。

世界のダウンストリームプロセス市場は、バイオ医薬品とバイオテクノロジー製品の需要増に牽引され、大きな成長を遂げようとしています。バイオ医薬品の効率的な精製・生産技術を求める企業が増えるにつれ、ダウンストリームプロセス技術は不可欠なものとなっています。メルクが無錫国家高新技術産業開発区と合意したような協力関係は、能力拡大に対する業界のコミットメントを示しています。しかし、高い設備コストや多額の初期投資といった課題は、特に中小企業にとっては成長の妨げになるかもしれないです。クロマトグラフィーとろ過の進歩は効率と拡張性を向上させ、シングルユース技術へのシフトはプロセスを合理化し、汚染リスクを最小限に抑え、生産スケジュールを早めています。バイオ医薬品セクターが成長を続けるにつれ、革新的な市場情勢が予想され、革新的なソリューションへの需要が急増すると思われます。

目次

イントロダクション

• 調査の目的
• 調査範囲
• 定義

調査手法

• 情報調達
• 二次と一次データの方法
• 市場規模予測
• 市場の前提条件と制限

エグゼクティブサマリー

• 世界市場の見通し
• 供給と需要の動向分析
• セグメント別機会分析

市場力学と見通し

• 市場概要
• 市場規模
• 市場力学
  • 促進要因と機会
  • 抑制要因と課題
• ポーターの分析

主な市場の考察

• 重要成功要因
• 競合の程度
• 主な投資機会
• 市場エコシステム
• 市場の魅力指数（2024年）
• PESTEL分析
• マクロ経済指標
• バリューチェーン分析
• 価格分析

ダウンストリームプロセス市場規模：技術別& CAGR（2025-2032）

• 市場概要
• 精製
• 固液分離
• 浄化/濃縮

ダウンストリームプロセス市場規模：製品別& CAGR（2025-2032）

• 市場概要
• クロマトグラフィーカラムと樹脂
• フィルター
• 膜吸着装置
• 使い捨て製品
• その他の製品
  • 消耗品および
  • アクセサリー

ダウンストリームプロセス市場規模：用途別& CAGR（2025-2032）

• 市場概要
• モノクローナル抗体の生産
• ワクチン製造
• インスリン産生
• 免疫グロブリンの生産
• エリスロポエチンの生産
• その他の用途
  • インターフェロン
  • 融合タンパク質
  • 成長ホルモン
  • 血液凝固因子
  • 抗凝固薬
  • 医療用酵素
  • 抗菌
  • 抗生物質
  • コロニー刺激因子

ダウンストリームプロセス市場規模：エンドユーザー別& CAGR（2025-2032）

• 市場概要
• バイオ医薬品メーカー
• 契約製造組織（CMO）

ダウンストリームプロセス市場規模：地域別& CAGR（2025-2032）

• 北米
  • 米国
  • カナダ
• 欧州
  • ドイツ
  • スペイン
  • フランス
  • 英国
  • イタリア
  • その他欧州地域
• アジア太平洋地域
  • 中国
  • インド
  • 日本
  • 韓国
  • その他アジア太平洋地域
• ラテンアメリカ
  • ブラジル
  • その他ラテンアメリカ地域
• 中東・アフリカ
  • GCC諸国
  • 南アフリカ
  • その他中東・アフリカ

競合情報

• 上位5社の比較
• 主要企業の市場ポジショニング（2024年）
• 主な市場企業が採用した戦略
• 最近の市場動向
• 企業の市場シェア分析（2024年）
• 主要企業の企業プロファイル
  • 企業の詳細
  • 製品ポートフォリオ分析
  • 企業のセグメント別シェア分析
  • 収益の前年比比較（2022-2024）

主要企業プロファイル

• Thermo Fisher Scientific Inc.（U.S.）
• Merck KGaA（MilliporeSigma）（Germany）
• Danaher Corporation（Cytiva）（U.S.）
• Sartorius Stedim Biotech S.A.（France）
• Lonza Group AG（Switzerland）
• 3M Company（U.S.）
• Boehringer Ingelheim International GmbH（Germany）
• Eppendorf AG（Germany）
• Repligen Corporation（U.S.）
• GE Healthcare（U.S.）
• Corning Incorporated（U.S.）
• Dover Corporation（U.S.）
• Asahi Kasei（Japan）
• Pall Corporation（U.S.）
• Bio-Rad Laboratories, Inc.（U.S.）
• Agilent Technologies Inc.（U.S.）
• Finesse Solutions, Inc.（U.S.）
• Novasep（France）
• Rentschler Biopharma（Germany）
• Vetter Pharma International GmbH（Germany）

結論と提言

Downstream Processing Market size was valued at USD 36.4 billion in 2023 and is poised to grow from USD 42.37 billion in 2024 to USD 142.78 billion by 2032, growing at a CAGR of 16.4% during the forecast period (2025-2032).

The Global Downstream Processing Market is set for significant growth driven by the rising demand for biopharmaceuticals and biotechnology products. As companies increasingly seek efficient purification and production techniques for biotherapeutics, downstream processing technologies become essential. Collaborations like Merck's agreement with Wuxi National High-tech Industrial Development Zone illustrate the industry's commitment to expanding capabilities. However, challenges such as high equipment costs and substantial initial investments may hinder growth, particularly for smaller firms. Advancements in chromatography and filtration are improving efficiency and scalability, while the shift toward single-use technologies is streamlining processes, minimizing contamination risks, and accelerating production timelines. As the biopharmaceutical sector continues to thrive, the demand for innovative downstream processing solutions will likely surge, promising a dynamic market landscape.

Top-down and bottom-up approaches were used to estimate and validate the size of the Downstream Processing market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Downstream Processing Market Segments Analysis

Global Downstream Processing Market is segmented by Technique, Product, Application, End User and region. Based on Technique, the market is segmented into Purification, Solid-liquid Separation and Clarification/Concentration. Based on Product, the market is segmented intoChromatographyColumns and Resins, Filters, Membrane Adsorbers, Single-use Products and Other Products. Based on Application, the market is segmented into Monoclonal Antibody Production, Vaccine Production, Insulin Production, Immunoglobulin Production, Erythropoietin Production and Other Applications. Based on End User, the market is segmented into Biopharmaceutical Manufacturers and Contract Manufacturing Organizations (CMOs). Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Driver of the Downstream Processing Market

The increasing need for biopharmaceuticals, including monoclonal antibodies, vaccines, and recombinant proteins, is driving growth in the downstream processing market. This sector is essential for the purification and isolation of these intricate biological products, which is vital for ensuring their safety and effectiveness. As the biopharmaceutical industry continues to expand, there is a corresponding surge in the demand for advanced downstream processing technologies and equipment. This trend highlights the critical role that downstream processing plays in the overall biopharmaceutical production pipeline, thereby making it a key driver for market development and innovation in the industry.

Restraints in the Downstream Processing Market

The Downstream Processing market faces various restraints due to the unique attributes of each biopharmaceutical product, including size, charge, solubility, and stability. These distinct characteristics can lead to complications such as low yields, challenging purification processes, and a heightened risk of degradation throughout purification stages. As a result, creating customized downstream processes for diverse products, while simultaneously tackling product-specific obstacles, can be quite intricate. This complexity necessitates a high level of expertise and considerable optimization efforts, ultimately making it a significant challenge for companies operating within this field to achieve efficient and effective processing solutions.

Market Trends of the Downstream Processing Market

The downstream processing market is witnessing a significant trend towards process intensification and continuous manufacturing methodologies, driven by the need for enhanced efficiency and productivity in biopharmaceutical production. Techniques such as continuous chromatography and continuous centrifugation are becoming increasingly popular, offering benefits like real-time monitoring and improved process control. These innovations facilitate the optimization of processing operations, resulting in higher yields and reduced processing times. As companies strive to shorten production timelines and minimize costs, the adoption of these advanced technologies is poised to reshape the downstream processing landscape, underscoring the industry's commitment to continuous improvement and operational excellence.

Table of Contents

Introduction

• Objectives of the Study
• Scope of the Report
• Definitions

Research Methodology

• Information Procurement
• Secondary & Primary Data Methods
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Global Market Outlook
• Supply & Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Overview
• Market Size
• Market Dynamics
  • Drivers & Opportunities
  • Restraints & Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of substitute
  • Bargaining power of buyers
  • Threat of new entrants
  • Bargaining power of suppliers

Key Market Insights

• Key Success Factors
• Degree of Competition
• Top Investment Pockets
• Market Ecosystem
• Market Attractiveness Index, 2024
• PESTEL Analysis
• Macro-Economic Indicators
• Value Chain Analysis
• Pricing Analysis

Global Downstream Processing Market Size by Technique & CAGR (2025-2032)

• Market Overview
• Purification
• Solid-liquid Separation
• Clarification/Concentration

Global Downstream Processing Market Size by Product & CAGR (2025-2032)

• Market Overview
• Chromatography Columns and Resins
• Filters
• Membrane Adsorbers
• Single-use Products
• Other Products
  • Consumables an
  • Accessories

Global Downstream Processing Market Size by Application & CAGR (2025-2032)

• Market Overview
• Monoclonal Antibody Production
• Vaccine Production
• Insulin Production
• Immunoglobulin Production
• Erythropoietin Production
• Other Applications
  • Interferons
  • Fusion Proteins
  • Growth Hormones
  • Blood Coagulation Factors
  • Anticoagulants
  • Medical Enzymes
  • Anti-bacterial
  • Antibiotics
  • Colony Stimulating Factors

Global Downstream Processing Market Size by End User & CAGR (2025-2032)

• Market Overview
• Biopharmaceutical Manufacturers
• Contract Manufacturing Organizations (CMOs)

Global Downstream Processing Market Size & CAGR (2025-2032)

• North America (Technique, Product, Application, End User)
  • US
  • Canada
• Europe (Technique, Product, Application, End User)
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific (Technique, Product, Application, End User)
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America (Technique, Product, Application, End User)
  • Brazil
  • Rest of Latin America
• Middle East & Africa (Technique, Product, Application, End User)
  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Competitive Intelligence

• Top 5 Player Comparison
• Market Positioning of Key Players, 2024
• Strategies Adopted by Key Market Players
• Recent Developments in the Market
• Company Market Share Analysis, 2024
• Company Profiles of All Key Players
  • Company Details
  • Product Portfolio Analysis
  • Company's Segmental Share Analysis
  • Revenue Y-O-Y Comparison (2022-2024)

Key Company Profiles

• Thermo Fisher Scientific Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA (MilliporeSigma) (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Danaher Corporation (Cytiva) (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Sartorius Stedim Biotech S.A. (France)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Lonza Group AG (Switzerland)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• 3M Company (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Boehringer Ingelheim International GmbH (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Eppendorf AG (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Repligen Corporation (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• GE Healthcare (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Corning Incorporated (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Dover Corporation (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Asahi Kasei (Japan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Pall Corporation (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio-Rad Laboratories, Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Agilent Technologies Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Finesse Solutions, Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Novasep (France)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Rentschler Biopharma (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Vetter Pharma International GmbH (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments

Conclusion & Recommendations