Product Code: RA100297
ALZHEIMER'S DISEASE MARKET: OVERVIEW
As per Roots Analysis, the global Alzheimer's disease market is estimated to grow from USD 12.4 billion in the current year to USD 19.1 billion by 2030, at a CAGR of 9% during the forecast period, till 2030.
The market sizing and opportunity analysis has been segmented across the following parameters:
Type of Treatment
- Symptomatic
- Disease Modifying
Symptomatic Indications
- Dementia
- Insomnia
- Other Physiological Symptoms
Key Geographical Regions
- North America
- Europe
- Asia-Pacific
- Rest of the World
ALZHEIMER'S DISEASE MARKET: GROWTH AND TRENDS
Alzheimer's disease is a progressive neurological disorder characterized by the death of brain cells, eventually leading to memory loss, cognitive dysfunction and dementia. Accounting for 60-70% of cases of dementia, Alzheimer's disease is known to be the sixth leading cause of death in the US. Presently, around seven million Americans of all ages are living with Alzheimer's and this number is projected to reach around 13 million by 2050. The primary symptoms associated with Alzheimer's disease include disorientation, personality / behavioral changes, confusion about events / time / place and severe memory loss. In addition, people suffering from this disease are known to face difficulty in speaking, swallowing and walking. Notably, as the disease progresses, the aforementioned symptoms become more pronounced and contribute to the death of brain cells. Consequently, the advancements in innovative Alzheimer's therapies offer lucrative opportunities to stakeholders engaged in this field.

Given the socioeconomic burden associated with Alzheimer's, pharmaceutical players have been looking for reliable diagnostic tests and effective Alzheimer's treatment alternatives that can slow the progression of this disease. Presently, over 160 companies, based in different regions of the world, have taken initiatives to develop drug therapies for Alzheimer's treatment.
ALZHEIMER'S DISEASE MARKET: KEY INSIGHTS
The report delves into the current state of the Alzheimer's disease market and identifies potential growth opportunities within the industry. Some key findings from the report include:
- Presently, over 160 companies, based in different regions of the world, have taken initiatives to develop drug therapies for Alzheimer's disease; the market is characterized by a mix of well-established and small firms.
- The pipeline features 240+ drug therapies being evaluated either as monotherapies or in combination with other interventions across different stages of development; most of these are designed for oral administration.

- There has been a notable increase in published scientific literature related to the diagnosis, treatment and management of Alzheimer's disease.
- The intellectual property associated with Alzheimer's disease has also increased, as numerous patents related to the drug molecules have been filed by / granted to various organizations.
- In the past few years, several organizations have extended financial support to aid the ongoing research and development activities in this domain.
- In the past decade, several clinical trials have been registered for evaluating drug therapies for Alzheimer's disease, across different geographical regions; a number of these trials have already been completed.
- Several investors have invested over USD 4 billion across 164 instances in the recent past, owing to the benefits and opportunities associated with drug candidates being developed to treat this clinical condition.
- The overall market opportunity for Alzheimer's disease therapies is likely to be distributed across different types of treatments, symptomatic indications and key geographical regions

ALZHEIMER'S DISEASE MARKET: KEY SEGMENTS
Disease Modifying Segment Occupy the Largest Share of the Global Alzheimer's Disease Market
Based on the type of treatment, the market is segmented into symptomatic and disease modifying types of treatments. At present, the disease modifying segment holds the maximum share of the global Alzheimer's disease market. Further, the symptomatic segment is likely to grow at a faster pace compared to the other segments.
By Symptomatic Indications, Insomnia is the Fastest Growing Segment of the Global Alzheimer's Disease Market During the Forecast Period
Based on the symptomatic indications, the market is segmented into dementia, insomnia, and other psychological symptoms. Currently, the dementia segment captures the highest proportion of the global Alzheimer's disease market owing to the growing number of therapeutic drugs being developed to treat cognitive symptoms. Further, it is worth highlighting that the Alzheimer's disease market for insomnia is likely to grow at a relatively higher CAGR.
North America Accounts for the Largest Share of the Market
Based on key geographical regions, the market is segmented into North America, Europe, and Asia-Pacific and Rest of the World. Currently, North America dominates the Alzheimer's disease market and accounts for the largest revenue share due to the favorable regulatory environment in this region. In fact, regulatory bodies in North America have recently approved several new Alzheimer's drugs, providing patients with access to innovative therapies and boosting market growth. Additionally, the market in Europe is likely to grow at a higher CAGR in the coming years.
Example Players in the Alzheimer's Disease Market
- AbbVie
- AC Immune
- Biogen
- Eisai
- Eli Lilly and Company
- GlaxoSmithKline
- Grifols
- Janssen Pharmaceutical
- Neurim Pharmaceuticals
- Novartis
- Novo Nordisk
- Roche
- Takeda Pharmaceutical
ALZHEIMER'S DISEASE MARKET: RESEARCH COVERAGE
- Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the global Alzheimer's disease market, focusing on key market segments, including [A] type of treatment, [B] symptomatic indications, and [C] key geographical regions.
- Market Landscape: A comprehensive evaluation of the drugs developed for the treatment of Alzheimer's, based on several relevant parameters, such as [A] current status of development, [B] phase of development of lead candidates, [C] type of biologic, [D] target disease stage, [E] type of treatment, [F] mechanism of action, [G] route of administration, [H] dosing frequency, [I] type of therapy and [J] path to clinic. Additionally, a comprehensive evaluation of the drug developer(s) involved in the domain, based on several relevant parameters, such as [K] year of establishment, [L] company size and [M] geographical location of headquarters.
- Company Profiles: In-depth profiles of key players engaged in the development of therapeutics for Alzheimer's disease, focusing on [A] overview of the company, [B] financial information (if available), [C] product portfolio, and [D] recent developments and an informed future outlook.
- Case Study: A detailed discussion on over 110 discontinued drugs and terminated trials, based on various parameters, such as [A] year of discontinuation, [B] reason(s) for discontinuation, [C] phase of discontinuation, [D] mechanism of action of the terminated drugs, [E] type of indication, [F] reason for termination, [G] affiliated stakeholders. Additionally, a detailed assessment of 180 terminated clinical trials, based on various parameters, such as [H] year of termination and [I] key geographies across which these trials were being conducted.
- Publication Analysis: An insightful analysis of around 20,000 peer-reviewed scientific articles related to research on Alzheimer's disease, based on various relevant parameters, such as [A] year of publication, [B] key focus area, [C] type of molecule, [D] popular keywords, and [E] key journals.
- Partnerships and Collaborations: An insightful analysis of the deals inked by stakeholders in the Alzheimer's disease market, based on several parameters, such as [A] year of partnership, [B] type of partnership, [C] focus area, [D] type of molecule, [E] most active players (in terms of the number of partnerships signed) and [F] geographical distribution of partnership activity.
- Funding and Investments: An in-depth analysis of the fundings raised by companies engaged in Alzheimer's disease market, based on relevant parameters, such as [A] year of funding, [B] amount invested, [C] type of funding, [D] geographical analysis, [E] most active players and [F] most active investors.
- Grants Analysis: A comprehensive assessment of grants that have been awarded to research institutes in the Alzheimer's disease domain, based on various relevant parameters, such as [A] year of grant award, [B] grant amount awarded, [C] administering institute center, [D] support period, [E] type of grant application, [F] grant activity code, [G] emerging focus area, [H] purpose of grant award, [I] type of recent organization, [J] popular NIH department and [K] prominent program officers.
- Clinical Trial Analysis: An insightful analysis of clinical trials related to therapies being developed for the treatment of Alzheimer's, based on several parameters, such as [A] current trial status, [B] trial registration year, [C] phase of development, [D] study design, [E] leading industry sponsors, [F] study focus, [G] target indication(s), [H] focus areas, [I] target therapeutic area(s), [J] enrolled patient population and [K] regional distribution of trials.
- Patent Analysis: An in-depth analysis of patents filed / granted till date in the Alzheimer's disease domain, based on various relevant parameters, such as [A] publication year, [B] geography, [C] CPC symbols, [D] emerging focus areas, [E] type of applicant, [F] leading industry players and [G] patent valuation analysis.
- Non-Pharmacological Interventions and Diagnostics: A detailed discussion on the various non-pharmacological interventions, including [A] cognition / emotion-oriented therapies, [B] sensory simulation therapies and [C] other psychological interventions. Additionally, a discussion of the companies that offer such solutions, providing information on the [D] devices / products and [E] mechanisms of action / working principles.
KEY QUESTIONS ANSWERED IN THIS REPORT
- How many companies are currently engaged in this market?
- Which are the leading companies in this market?
- What factors are likely to influence the evolution of this market?
- What is the current and future market size?
- What is the CAGR of this market?
- How is the current and future market opportunity likely to be distributed across key market segments?
REASONS TO BUY THIS REPORT
- The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
- Stakeholders can leverage the report to gain a deeper understanding of the competitive dynamics within the market. By analyzing the competitive landscape, businesses can make informed decisions to optimize their market positioning and develop effective go-to-market strategies.
- The report offers stakeholders a comprehensive overview of the market, including key drivers, barriers, opportunities, and challenges. This information empowers stakeholders to stay abreast of market trends and make data-driven decisions to capitalize on growth prospects.
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TABLE OF CONTENTS
1. PREFACE
- 1.1. Scope of the Report
- 1.2. Research Methodology
- 1.3. Key Questions Answered
- 1.4. Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
- 3.1. An Overview of Alzheimer's Disease
- 3.1.1. Alzheimer's Disease: Signs and Symptoms
- 3.1.2. Causes of Alzheimer's Disease
- 3.1.3. Stages of Alzheimer's Disease
- 3.2. Alzheimer's Disease Management: Programs Undertaken by The National Institutes of Health
- 3.3. Alzheimer's Disease Management
- 3.4. Digital Biomarkers in Alzheimer's Disease
- 3.4.1. Potential of Digital Biomarkers in Alzheimer's Disease
- 3.4.2. Sensors or Digital Senses in Wearable / Mobile Devices for Alzheimer's Disease
4. PIPELINE REVIEW: MARKETED AND CLINICAL- STAGE DRUGS
- 4.1. Analysis Methodology and Key Parameters
- 4.2. Alzheimer's Disease Therapies: Marketed and Development Pipeline
- 4.2.1. Analysis by Phase of Development
- 4.2.2. Analysis by Type of Molecule
- 4.2.3. Analysis by Target Disease Stage
- 4.2.4. Analysis by Type of Treatment
- 4.2.5. Analysis by Mechanism of Action
- 4.2.6. Analysis by Route of Administration
- 4.2.7. Analysis by Dosing Frequency
- 4.2.8. Analysis by Type of Therapy
- 4.2.9. Analysis by Path to Clinic
- 4.2.10. Grid Analysis: Distribution by Phase of Development, Path to Clinic and Type of Therapy
- 4.4. Alzheimer's Disease Therapies: List of Developers
- 4.4.1. Analysis by Year of Establishment
- 4.4.2. Analysis by Company Size and Geographical Location of Headquarters
- 4.4.3. Leading Players: Analysis by Number of Therapies
- 4.4.4. Analysis by Geography
5. COMPANY PROFILES
- 5.1. AbbVie
- 5.1.1. Company Overview
- 5.1.2. Financial Information
- 5.1.3. Product Portfolio
- 5.1.4. Recent Developments and Future Outlook
- 5.2. AC Immune
- 5.2.1. Company Overview
- 5.2.2. Financial Information
- 5.2.3. Product Portfolio
- 5.2.4. Recent Developments and Future Outlook
- 5.3. Biogen
- 5.3.1. Company Overview
- 5.3.2. Financial Information
- 5.3.3. Product Portfolio
- 5.3.4. Recent Developments and Future Outlook
- 5.4. Eisai
- 5.4.1. Company Overview
- 5.4.2. Financial Information
- 5.4.3. Product Portfolio
- 5.4.4. Recent Developments and Future Outlook
- 5.5. Eli Lilly and Company
- 5.5.1. Company Overview
- 5.5.2. Financial Information
- 5.5.3. Product Portfolio
- 5.5.4. Recent Developments and Future Outlook
- 5.6. GlaxoSmithKline
- 5.6.1. Company Overview
- 5.6.2. Financial Information
- 5.6.3. Product Portfolio
- 5.6.4. Recent Developments and Future Outlook
- 5.7. Grifols
- 5.7.1. Company Overview
- 5.7.2. Financial Information
- 5.7.3. Product Portfolio
- 5.7.4. Recent Developments and Future Outlook
- 5.8. Janssen Pharmaceutical
- 5.8.1. Company Overview
- 5.8.2. Financial Information
- 5.8.3. Product Portfolio
- 5.8.4. Recent Developments and Future Outlook
- 5.9. Neurim Pharmaceuticals
- 5.9.1. Company Overview
- 5.9.2. Financial Information
- 5.9.3. Product Portfolio
- 5.9.4. Recent Developments and Future Outlook
- 5.10. Novartis
- 5.10.1. Company Overview
- 5.10.2. Financial Information
- 5.10.3. Product Portfolio
- 5.10.4. Recent Developments and Future Outlook
- 5.11. Novo Nordisk
- 5.11.1. Company Overview
- 5.11.2. Financial Information
- 5.11.3. Product Portfolio
- 5.11.4. Recent Developments and Future Outlook
- 5.12. Roche
- 5.12.1. Company Overview
- 5.12.2. Financial Information
- 5.12.3. Product Portfolio
- 5.12.4. Recent Developments and Future Outlook
- 5.13. Takeda Pharmaceutical
- 5.13.1. Company Overview
- 5.13.2. Financial Information
- 5.13.3. Product Portfolio
- 5.13.4. Recent Developments and Future Outlook
6. CASE STUDY: TERMINATED DRUGS
- 6.1. Chapter Overview
- 6.2. Alzheimer's Disease Therapies: List of Terminated Drugs
- 6.2.1. Analysis by Year of Discontinuation
- 6.2.2. Analysis by Phase of Discontinuation
- 6.2.3. Analysis by Mechanism of Action
- 6.2.4. Analysis by Type of Indication
- 6.2.5. Analysis by Reason for Termination
- 6.2.6. Analysis by Affiliated Stakeholders
- 6.3. Alzheimer's Disease Therapies: List of Terminated Clinical Trials
- 6.3.1. Distribution by Study Start Year and Year of Termination of Clinical Trials
- 6.3.2. Analysis by Location of Trials
- 6.4. Concluding Remarks
7. PUBLICATION ANALYSIS
- 7.1. Analysis Methodology and Key Parameters
- 7.2. Alzheimer's Disease: List of Publications
- 7.3. Analysis by Year of Publication
- 7.4. Analysis by Key Focus Area
- 7.5. Word Cloud of Study Titles
- 7.6. Top Journal: Analysis by Number of Publications
- 7.6. Top Author: Analysis by Number of Publications
8. PARTNERSHIPS AND COLLABORATIONS
- 8.1. Analysis Methodology and Key Parameters
- 8.2. Partnership Models
- 8.3. Alzheimer's Disease: List of Partnerships and Collaborations
- 8.3.1. Analysis by Year of Partnership
- 8.3.2. Analysis by Type of Partnership
- 8.3.3. Analysis by Type of Partnership and Focus Area of Partnership
- 8.3.4. Analysis by Type of Partnership and Type of Molecule
- 8.3.5. Most Active Players: Analysis by Number of Partnerships
- 8.3.6. Regional Analysis
- 8.3.7. Intercontinental and Intracontinental Agreements
9. FUNDING AND INVESTMENT ANALYSIS
- 9.1. Analysis Methodology and Key Parameters
- 9.2. Types of Funding
- 9.3. Funding and Investment Analysis
- 9.3.1. Analysis by Year of Investment
- 9.3.2. Analysis by Amount Invested
- 9.3.3. Analysis by Type of Funding
- 9.3.4 Analysis by Amount Invested Across Different Types of Molecules
- 9.3.5 Analysis by Amount Invested Across Different Types of Mechanism of Action
- 9.3.6. Regional Analysis by Amount Invested
- 9.3.7. Most Active Players: Analysis by Number of Funding Instances
- 9.3.8. Most Active Investors: Analysis by Amount Funded
10. GRANT ANALYSIS
- 10.1. Analysis Methodology and Key Parameters
- 10.2. Alzheimer's Disease: List of Academic Grants
- 10.2.1. Analysis by Year of Grant Award
- 10.2.2. Analysis by Grant Amount Awarded
- 10.2.3. Analysis by Administering Institute Center
- 10.2.4. Analysis by Support Period
- 10.2.5. Analysis by Administering Institute Center and Support Year
- 10.2.6. Analysis by Type of Grant Application
- 10.2.7. Analysis by Grant Activity Code
- 10.2.8. Word Cloud of Study Titles
- 10.2.9. Analysis by Purpose of Grant Award
- 10.2.10. Analysis by Type of Recipient Organization
- 10.2.11. Popular NIH Departments: Analysis by Number of Grants
- 10.2.12. Prominent Program Officers: Analysis by Number of Grants
11. CLINICAL TRIAL ANALYSIS
- 11.1. Analysis Methodology and Key Parameters
- 11.2. Alzheimer's Disease: Clinical Trial Analysis
- 11.3.1. Analysis by Trial Status
- 11.3.2. Analysis by Trial Registration Year
- 11.3.3. Analysis by Type of Sponsor / Collaborator
- 11.3.3. Analysis by Type of Study Design
- 11.3.4. Analysis by Registration Year and Type of Study
- 11.3.5. Analysis by Patient Enrollment
- 11.3.6. Year-wise Trend of Completed and Recruiting Trials
- 11.3.7. Analysis by Age Category
- 11.3.8. Word Cloud of Study Titles
- 11.3.9. Most Active Industry Players: Analysis by Number of Registered Trials
- 11.3.10. Most Active Non- Industry Players: Analysis by Number of Registered Trials
- 11.3.11. Analysis by Trial Location
- 11.3.12. Analysis by Trial Status and Geography
12. PATENT ANALYSIS
- 12.1. Analysis Methodology and Key Parameters
- 12.2. Alzheimer's Disease: Patent Analysis
- 12.2.1. Analysis by Patent Application Year
- 12.2.2. Analysis by Geography
- 12.2.3. Analysis by CPC Symbols
- 12.2.4. Word Cloud: Emerging Focus Areas
- 12.2.5. Analysis by Type of Applicant
- 12.2.6. Leading Players: Analysis by Number of Patents
- 12.2.7 Leading Players: Analysis by Number of International Patents
- 12.2.8. Patent Valuation Analysis
13. NON-PHARMACOLOGICAL INTERVENTIONS AND DIAGNOSTICS
- 13.1. Non-Pharmacological Interventions for Alzheimer's Disease
- 13.1.1. Cognition / Emotion-Oriented Interventions
- 13.1.1.1. Reminiscence Therapy
- 13.1.1.2. Simulated Presence Therapy
- 13.1.2. Sensory Stimulation-based Interventions
- 13.1.2.1. Virtual Reality
- 13.1.2.2. Music Therapy
- 13.1.2.3. Light Therapy
- 13.1.2.4. Aromatherapy
- 13.1.2.5. Reflexology
- 13.1.3. Other Psycho-social Interventions
- 13.1.3.1. Animal-Assisted Therapy
14. MARKET SIZING AND OPPORTUNITY ANALYSIS
- 14.1. Forecast Methodology and Key Assumptions
- 14.2. Global Alzheimer's Disease Market, Till 2035
- 14.3. Global Alzheimer's Disease Market, Till 2035: Distribution by Type of Treatment
- 14.4. Global Alzheimer's Disease Market, Till 2035: Distribution by Type of Target Disease Indication
- 14.5. Global Alzheimer's Disease Market, Till 2035: Distribution by Geography
- 14.5.1. Alzheimer's Disease Market in North America, Till 2035
- 14.5.1.1. Alzheimer's Disease Market in North America, Till 2035: Distribution by Type of Treatment
- 14.5.1.1.1. Alzheimer's Disease Market in North America, Till 2035: Distribution by Symptomatic Treatment
- 14.5.1.1.1.1. Alzheimer's Disease Market in North America, Till 2035: Share of Dementia in Symptomatic Treatment Market
- 14.5.1.1.1.2. Alzheimer's Disease Market in North America, Till 2035: Share of Insomnia in Symptomatic Treatment Market
- 14.5.1.1.1.3. Alzheimer's Disease Market in North America, Till 2035: Share of Other Psychological Symptoms in Symptomatic Treatment Market
- 14.5.1.1.2. Alzheimer's Disease Market in North America, Till 2035: Distribution by Disease Modifying Treatment
- 14.5.2. Alzheimer's Disease Market in Europe, Till 2035
- 14.5.2.1. Alzheimer's Disease Market in Europe, Till 2035: Distribution by Type of Treatment
- 14.5.2.1.1. Alzheimer's Disease Market in Europe, Till 2035: Distribution by Symptomatic Treatment
- 14.5.2.1.1.1. Alzheimer's Disease Market in Europe, Till 2035: Share of Dementia in Symptomatic Treatment Market
- 14.5.2.1.1.2. Alzheimer's Disease Market in Europe, Till 2035: Share of Insomnia in Symptomatic Treatment Market
- 14.5.2.1.1.3. Alzheimer's Disease Market in Europe, Till 2035: Share of Other Psychological Symptoms in Symptomatic Treatment Market
- 14.5.2.1.2. Alzheimer's Disease Market in Europe, Till 2035: Distribution by Disease Modifying Treatment
- 14.5.3. Alzheimer's Disease Market in Asia-Pacific, Till 2035
- 14.5.3.1. Alzheimer's Disease Market in Asia-Pacific, Till 2035: Distribution by Type of Treatment
- 14.5.3.1.1. Alzheimer's Disease Market in Asia-Pacific, Till 2035: Distribution by Symptomatic Treatment
- 14.5.3.1.1.1. Alzheimer's Disease Market in Asia-Pacific, Till 2035: Share of Dementia in Symptomatic Treatment Market
- 14.5.3.1.1.2. Alzheimer's Disease Market in Asia-Pacific, Till 2035: Share of Insomnia in Symptomatic Treatment Market
- 14.5.3.1.1.3. Alzheimer's Disease Market in Asia-Pacific, Till 2035: Share of Other Psychological Symptoms in Symptomatic Treatment Market
- 14.5.3.1.2. Alzheimer's Disease Market in Asia-Pacific, Till 2035: Distribution by Disease Modifying Treatment
15. CONCLUDING REMARKS
16. EXECUTIVE INSIGHTS
- 16.1. Cognition Therapeutics
- 16.1.1. Company Snapshot
- 16.1.1. Interview Transcript: Kenneth Moch (President and Chief Executive Officer)
- 16.2. ArmaGen
- 16.2.1. Company Snapshot
- 16.2.2. Interview Transcript: Mathias Schmidt (Chief Executive Officer)
- 16.2. ICB International
- 16.2.1. Company Snapshot
- 16.3.2. Interview Transcript: Ram Bhatt (Chief Executive Officer, Chairman and Founder)
17. APPENDIX 1: TABULATED DATA
18. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS