Product Code: RA100502
The GLP-1 Market is valued at USD 49.3 billion in 2024 growing at a CAGR of 11.1% during the forecast period 2024-2035.
GLP-1 receptor agonists are a class of medications primarily utilized for managing blood sugar levels / glucose levels in individuals with type 2 diabetes. Further, a few GLP-1 agonists can also help in the treatment of obesity and related heart disease (cardiovascular disease). It is important to mention that, according to a study conducted by Lancet, 42.4% of adult individuals in the US are obese. Moreover, according to the World Health Organization (WHO), 4 million people die annually due to obesity. In addition, nearly 530 million global adult population suffer from diabetes, with 98% of those having type 2 diabetes and prevalence of diabetes is expected to increase to nearly 1.3 billion by 2050, making it a significant public health concern. It is worth mentioning that, according to the American Diabetes Association, diabetes was the eighth leading cause of death in 2021.
In recent years, there has been a notable shift in consumer lifestyles driven by the growing influence of social media, celebrity endorsements and direct-to-consumer advertising. This has led to a surge in the demand for weight loss and type 2 diabetes treatment solutions, which is likely to spur innovation and market expansion in this domain. In order to address the increasing demand for type 2 diabetes and body weight management drugs, various initiatives have been undertaken by players to develop drugs for treatment of such indications; of these, GLP-1 agonist drugs have emerged as promising option driven by the significant number of positive clinical trial results, along with continuous research and development efforts.
Over the past few years, a number of GLP-1 drugs targeting obesity and type 2 diabetes have received regulatory approvals globally. In 2024, the FDA approved Wegovy, developed by Novo Nordisk, for the treatment of serious heart problems in adults with obesity or overweight. Given the lucrative potential of these drugs, the GLP-1 market, also known as GLP-1 receptor agonist market, has gained significant attention of both private and public investors leading to the substantial market growth during the forecast period.
Key Market Segments
Type of Molecule
- Biologics
- Small Molecules
Active Compound Used
- Dulaglutide
- Liraglutide
- Orforglipron
- Retatrutide
- Semaglutide
- Survodutide
- Tirzepatide
- Other Active Compounds
Type of GLP-1 Agonist Drugs
- Long-acting GLP-1 Agonist
- Short-acting GLP-1 Agonist
Type of Agonist
- Single agonist
- Dual agonist
- Tri-agonist
Route of Administration
Target Indication
- Alzheimer's Disease
- Non-Alcoholic Steatohepatitis
- Obesity
- Sleep Apnea
- Type 2 Diabetes
Key Geographical Regions
- North America
- Europe
- Asia Pacific
- Latin America
Leading Drug Developers
- Boehringer Ingelheim
- Eli Lilly
- Novo Nordisk
- Other Developers
Research Coverage:
- A detailed assessment of the overall market landscape of GLP-1 drugs, along with information on several relevant parameters, such as stage of development (Marketed, Clinical (Phase III, Phase II, Phase I), IND-Enabling and Discovery / Preclinical), type of molecule (biologics and small molecules), active compound used (ecnoglutide, efocipegtrutide, exenatide, froniglutide, isupaglutide, liraglutide, lixisenatide, semaglutide, tirzepatide, utreglutide and other active compounds), GLP-1 agonist (single-agonist, dual-agonist and tri-agonist), route of administration (intraarticular, oral, subcutaneous and sublingual), dosing frequency (single dose, once monthly, once weekly, twice weekly, once daily and twice daily), type of therapy (combination therapy and monotherapy), target indication (Alzheimer's disease, congenital hyperinsulinism, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis (NASH drugs), obesity, obstructive apnea syndrome, Parkinson's disease, sarcopenia, type 2 diabetes and other target indication) and therapeutic area (genetic disorders, inflammatory disorders, metabolic disorders, neurological disorders, neuromuscular disorders, respiratory disorder and other therapeutic areas). In addition, the chapter provides a detailed list of developers engaged in developing GLP-1 drugs, along with analysis based on various parameters, such as year of establishment, company size (in terms of employee count) and location of headquarters (North America, Europe and Asia-Pacific and Rest of the world) of the players involved in this market space.
- Elaborate profiles of prominent players developing GLP-1 drugs (shortlisted based on the number of drugs in its pipeline). Each profile features a brief overview of the company (including information on its year of establishment, number of employees, location of headquarters and leadership team), financial information, drug portfolio, recent developments and an informed future outlook.
- A detailed analysis of the partnerships inked between stakeholders in the GLP-1 industry, based on several parameters, such as year of partnership, type of partnership, type of molecule, type of partner and most active players (in terms of the number of partnerships signed) and regional distribution of partnership activity in this domain, since 2020
- An in-depth analysis of the factors that can impact the growth of GLP-1 companies. It also features identification and analysis of key GLP-1 market drivers, potential restraints, emerging opportunities, and existing challenges.
- A detailed GLP-1 receptor agonist market forecast analysis in order to estimate the existing market size and future opportunity for GLP-1 companies over the next decade. Based on multiple parameters, such as likely adoption trends, we have provided an informed estimate on the market evolution during the forecast period till 2035. The report also features the likely distribution of the current and forecasted opportunity within the global GLP-1 receptor agonist market. Further, in order to account for future uncertainties and to add robustness to our model, we have provided three forecast scenarios, namely conservative, base and optimistic scenarios, representing different tracks of the industry's growth.
- Detailed projection of the current and future opportunity within the GLP-1 market across different types of molecules, namely biologics and small molecules.
- Detailed projection of the current and future opportunity within the GLP-1 receptor agonist market across different active compound used, namely dulaglutide, liraglutide, orforglipron, retatrutide, semaglutide, survodutide, tirzepatide and other active compounds.
- Detailed projection of the current and future opportunity within the GLP-1 industry across different types of GLP-1 agonist drug, namely long-acting GLP-1 agonist and short-acting GLP-1 agonist.
- Detailed projection of the current and future opportunity within the GLP-1 industry across different types of agonists, namely single-agonist, dual-agonist and tri-agonist.
- Detailed projection of the current and future opportunity within the GLP-1 receptor agonist market across different routes of administration, namely oral and parenteral.
- Detailed projection of the current and future opportunity within the GLP-1 market across different target indication, namely Alzheimer's disease, non-alcoholic steatohepatitis, obesity, sleep apnea, type 2 diabetes.
- Detailed projection of the current and future opportunity within the GLP-1 industry across different key geographical regions, namely North America, Europe, Asia-Pacific and Latin America.
- Detailed projections of the current and future GLP-1 market for the sales of forecasted drugs.
- Detailed projections of the current and future revenues from the sales of drugs developed by the leading players, namely Boehringer Ingelheim, Eli Lilly, Novo Nordisk and other players.
Key Benefits of Buying this Report
- The report offers market leaders and newcomers valuable insights into revenue estimations for both the overall market and its sub-segments.
- Stakeholders can utilize the report to enhance their understanding of the competitive landscape, allowing for improved business positioning and more effective go-to-market strategies.
- The report provides stakeholders with a pulse on the GLP-1 Market, furnishing them with essential information on significant market drivers, barriers, opportunities, and challenges.
Leading Market Companies
- AstraZeneca
- Biolingus
- Boehringer Ingelheim
- D&D Pharmatech
- Eli Lilly
- Gmax Biopharm
- Hanmi Pharmaceutical
- Innogen
- Novo Nordisk
- PegBio
- Pfizer
- QL Biopharma
- Roche
- Sanofi
- Sciwind Biosciences
- Tonghua Dongbao Pharmaceutical
- Viking Therapeutics
- Vivani
- vTv Therapeutic
TABLE OF CONTENTS
1 BACKGROUND
- 1.1. Context
- 1.2. Project Objectives
2 RESEARCH METHODOLOGY
- 2.1. Chapter Overview
- 2.2. Research Assumptions
- 2.3. Project Methodology
- 2.4. Forecast Methodology
- 2.5. Robust Quality Control
- 2.6. Key Market Segmentations
- 2.7. Key Considerations
- 2.7.1. Demographics
- 2.7.2. Economic Factors
- 2.7.3. Government Regulations
- 2.7.4. Supply Chain
- 2.7.5. COVID Impact
- 2.7.6. Market Access
- 2.7.7. Healthcare Policies
- 2.7.8. Industry Consolidation
3. ECONOMIC AND OTHER PROJECT SPECIFIC CONSIDERATIONS
- 3.1. Chapter Overview
- 3.2. Market Dynamics
- 3.2.1. Time Period
- 3.2.1.1. Historical Trends
- 3.2.1.2. Current and Forecasted Estimates
- 3.2.2. Currency Coverage and Foreign Exchange Rate
- 3.2.2.1. Major Currencies Affecting the Market
- 3.2.2.2. Factors affecting Currency Fluctuations and Foreign Exchange Rates
- 3.2.2.3. Impact of Foreign Exchange Rate Volatility on Market
- 3.2.2.4. Strategies For Mitigating Foreign Exchange Risk
- 3.2.3. Trade Policies
- 3.2.3.1. Impact of Trade Barriers on the Market
- 3.2.3.2. Strategies for Mitigating the Risks Associated with Trade Barriers
- 3.2.4. Recession
- 3.2.4.1. Historical Analysis of Past Recessions and Lessons Learnt
- 3.2.4.2. Assessment of Current Economic Conditions and Potential Impact on the Market
- 3.2.5. Inflation
- 3.2.5.1. Measurement and Analysis of Inflationary Pressures in the Economy
- 3.2.5.2. Potential Impact of Inflation on the Market Evolution
4 EXECUTIVE SUMMARY
5 INTRODUCTION
- 5.1. Overview of the GLP-1 Drug
- 5.1.1. Challenges Associated with GLP-1 Drugs
- 5.1.2. Mechanism of Action of GLP-1 Drugs
- 5.2. Important Facts in GLP-1 Domain
- 5.3. Future Perspectives
6 MARKET LANDSCAPE: GLP-1 DRUGS
- 6.1. GLP-1 Drugs: Market Landscape
- 6.1.1. Analysis by Status of Development
- 6.1.2. Analysis by Type of Molecule
- 6.1.3. Analysis by Active Compound Used
- 6.1.4. Analysis by Type of Agonist
- 6.1.5. Analysis by Route of Administration
- 6.1.6. Analysis by Dosing Frequency
- 6.1.7. Analysis by Type of Therapy
- 6.1.8. Analysis by Target Indication
- 6.1.9. Analysis by Therapeutic Area
- 6.2. GLP-1 Drugs: Developer Landscape
- 6.2.1. Analysis by Year of Establishment
- 6.2.2. Analysis by Company Size
- 6.2.3. Analysis by Location of Headquarters
- 6.2.4. Analysis by Location of Headquarters (Country) and Status of Development
- 6.2.5. Most Active Developers: Analysis by Number of Therapies
7 GLP-1 DRUGS: DETAILED COMPANY PROFILES
- 7.1. Chapter Overview
- 7.1.1. AstraZeneca
- 7.1.1.1. Company Overview
- 7.1.1.2. Pipeline Portfolio
- 7.1.1.3. Financial Details
- 7.1.1.4. Recent Developments and Future Outlook
- 7.1.2. D&D Pharmatech
- 7.1.2.1. Company Overview
- 7.1.2.2. Pipeline Portfolio
- 7.1.2.3. Financial Details
- 7.1.2.4. Recent Developments and Future Outlook
- 7.1.3. Eli Lilly
- 7.1.3.1. Company Overview
- 7.1.3.2. Pipeline Portfolio
- 7.1.3.3. Financial Details
- 7.1.3.4. Recent Developments and Future Outlook
- 7.1.4. Novo Nordisk
- 7.1.4.1. Company Overview
- 7.1.4.2. Pipeline Portfolio
- 7.1.4.3. Financial Details
- 7.1.4.4. Recent Developments and Future Outlook
- 7.1.5. Pfizer
- 7.1.5.1. Company Overview
- 7.1.5.2. Pipeline Portfolio
- 7.1.5.3. Financial Details
- 7.1.5.4. Recent Developments and Future Outlook
- 7.1.6. Sanofi
- 7.1.6.1. Company Overview
- 7.1.6.2. Pipeline Portfolio
- 7.1.6.3. Financial Details
- 7.1.6.4. Recent Developments and Future Outlook
- 7.1.7. Tonghua Dongbao Pharmaceutical
- 7.1.7.1. Company Overview
- 7.1.7.2. Pipeline Portfolio
- 7.1.7.3. Financial Details
- 7.1.7.4. Recent Developments and Future Outlook
- 7.1.8. Vivani
- 7.1.8.1. Company Overview
- 7.1.8.2. Pipeline Portfolio
- 7.1.8.3. Financial Details
- 7.2.8.4. Recent Developments and Future Outlook
8 GLP-1 DRUGS: BRIEF COMPANY PROFILES
- 8.1. Chapter Overview
- 8.1.1. Biolingus
- 8.1.1.1. Company Overview
- 8.1.1.2. Pipeline Portfolio
- 8.1.2. Boehringer Ingelheim
- 8.1.2.1. Company Overview
- 8.1.2.2. Pipeline Portfolio
- 8.1.3. Gmax Biopharm
- 8.1.3.1. Company Overview
- 8.1.3.2. Pipeline Portfolio
- 8.1.4. Hanmi Pharmaceutical
- 8.1.4.1. Company Overview
- 8.1.4.2. Pipeline Portfolio
- 8.1.5. Innogen
- 8.1.5.1. Company Overview
- 8.1.5.2. Pipeline Portfolio
- 8.1.6. PegBio
- 8.1.6.1. Company Overview
- 8.1.6.2. Pipeline Portfolio
- 8.1.7. QL Biopharma
- 8.1.7.1. Company Overview
- 8.1.7.2. Pipeline Portfolio
- 8.1.8. Roche
- 8.1.8.1. Company Overview
- 8.1.8.2. Pipeline Portfolio
- 8.1.9. Sciwind Biosciences
- 8.1.9.1. Company Overview
- 8.1.9.2. Pipeline Portfolio
- 8.1.10. Viking Therapeutics
- 8.1.10.1. Company Overview
- 8.1.10.2. Pipeline Portfolio
- 8.1.11. vTv Therapeutics
- 8.1.11.1. Company Overview
- 8.1.11.2. Pipeline Portfolio
9 PARTNERSHIPS AND COLLABORATIONS
- 9.1. Chapter Overview
- 9.2. Partnership Models
- 9.3. GLP-1 Market: Partnerships and Collaborations
- 9.3.1. Analysis by Year of Partnership
- 9.3.2. Analysis by Type of Partnership
- 9.3.3. Analysis by Focus Area
- 9.3.4. Analysis by Year and Type of Partnership
- 9.3.5. Most Active Players: Analysis by Number of Partnerships
- 9.3.6. Analysis by Geography
- 9.3.6.1. Intercontinental and Intracontinental Deals
- 9.3.6.2. Local and International Deals
10 MARKET IMPACT ANALYSIS: DRIVERS, RESTRAINTS, OPPORTUNITIES AND CHALLENGES
- 10.1. Chapter Overview
- 10.2. Market Drivers
- 10.3. Market Restraints
- 10.4. Market Opportunities
- 10.5. Market Challenges
- 10.6. Conclusion
11 GLOBAL GLP-1 MARKET
- 11.1. Assumptions and Methodology
- 11.2. Global GLP-1 Market, Historical Trends and Forecasted Estimates, till 2035
- 11.2.1. Scenario Analysis
- 11.2.1.1. Conservative Scenario
- 11.2.1.2. Optimistic Scenario
- 11.2.2. Key Market Segmentations
12 GLP-1 MARKET, BY TYPE OF MOLECULE
- 12.1. Assumptions and Methodology
- 12.2. GLP-1 Market: Distribution by Type of Molecule, 2020, 2024 and 2035
- 12.2.1. GLP-1 Market for Biologics, till 2035
- 12.2.2. GLP-1 Market for Small Molecules, till 2035
- 12.3. Data Triangulation and Validation
13 GLP-1 MARKET, BY ACTIVE COMPOUND USED
- 13.1. Assumptions and Methodology
- 13.2. GLP-1 Market: Distribution by Active Compound Used, 2020, 2024 and 2035
- 13.2.1. GLP-1 Market for Dulaglutide, till 2035
- 13.2.2. GLP-1 Market for Liraglutide, till 2035
- 13.2.3. GLP-1 Market for Orforglipron, till 2035
- 13.2.4. GLP-1 Market for Retatrutide, till 2035
- 13.2.5. GLP-1 Market for Semaglutide, till 2035
- 13.2.6. GLP-1 Market for Survodutide, till 2035
- 13.2.7. GLP-1 Market for Tirzepatide, till 2035
- 13.2.8. GLP-1 Market for Other Active Compounds, till 2035
- 13.3 Data Triangulation and Validation
14 GLP-1 MARKET, BY TYPE OF GLP-1 AGONIST DURGS
- 14.1. Assumptions and Methodology
- 14.2. GLP-1 Market: Distribution by Type of GLP-1 Agonist Drugs, 2020, 2024 and 2035
- 14.2.1. GLP-1 Market for Long-acting GLP-1 Agonist, till 2035
- 14.2.2. GLP-1 Market for Short-acting GLP-1 Agonist, till 2035
- 14.3. Data Triangulation and Validation
15 GLP-1 MARKET, BY GLP-1 AGONIST
- 15.1. Assumptions and Methodology
- 15.2. GLP-1 Market: Distribution by GLP-1 Agonist, 2020, 2024 and 2035
- 15.2.1. GLP-1 Market for Single-agonist, till 2035
- 15.2.2. GLP-1 Market for Dual-agonist, till 2035
- 15.2.3. GLP-1 Market for Tri-agonist, till 2035
- 15.3. Data Triangulation and Validation
16 GLP-1 MARKET, BY ROUTE OF ADMINISTRATION
- 16.1. Assumptions and Methodology
- 16.2. GLP-1 Market: Distribution by Route of Administration, 2020, 2024 and 2035
- 16.2.1. GLP-1 Market for Oral Route, till 2035
- 16.2.2. GLP-1 Market for Parenteral Route, till 2035
- 16.3. Data Triangulation and Validation
17 GLP-1 MARKET, BY TARGET INDICATION
- 17.1. Assumptions and Methodology
- 17.2. GLP-1 Market: Distribution by Target Indication, 2020, 2024 and 2035
- 17.2.1. GLP-1 Market for Alzheimer's Disease, till 2035
- 17.2.2. GLP-1 Market for Non-Alcoholic Steatohepatitis, till 2035
- 17.2.3. GLP-1 Market for Obesity, till 2035
- 17.2.4. GLP-1 Market for Sleep Apnea, till 2035
- 17.2.5. GLP-1 Market for Type 2 Diabetes, till 2035
- 17.3. Data Triangulation and Validation
18 GLP-1 MARKET, BY GEOGRAPHY
- 18.1. Assumptions and Methodology
- 18.2. GLP-1 Market: Distribution by Geography, 2020, 2024 and 2035
- 18.2.1. GLP-1 Market in North America, till 2035
- 18.2.2. GLP-1 Market in Europe, till 2035
- 18.2.3. GLP-1 Market in Asia-Pacific, till 2035
- 18.2.4. GLP-1 Market in Latin America, till 2035
- 18.3. Data Triangulation and Validation
19 GLP-1 MARKET, SALES FORECAST OF GLP-1 DRUGS
- 19.1. Chapter Overview
- 19.2. Approved GLP-1 Drugs: Sales Forecast
- 19.2.1. Feisumei (Benaglutide) Sales Forecast
- 19.2.2. Fu Laimei (Polyethylene Glycol Loxenatide) Sales Forecast
- 19.2.3. Mounjaro (Tirzepatide) Sales Forecast
- 19.2.4. Ozempic (Semaglutide Subcutaneous) Sales Forecast
- 19.2.5. Rybelsus (Semaglutide Oral) Sales Forecast
- 19.2.6. Saxenda (Liraglutide) Sales Forecast
- 19.2.7. Trulicity (Dulaglutide) Sales Forecast
- 19.2.8. Victoza (Liraglutide) Sales Forecast
- 19.2.9. Wegovy (Semaglutide Subcutaneous) Sales Forecast
- 19.2.10. XULTOPHY (Insulin Degludec / Liraglutide ) Sales Forecast
- 19.2.11. Zepbound (Tirzepatide) Sales Forecast
- 19.3. Phase III GLP-1 Drugs: Sales Forecast
- 19.3.1. GMA102 / Glutazumab Sales Forecast
- 19.3.2. JY09 Sales Forecast
- 19.3.3. LY3298176 / Tirzepatide Sales Forecast
- 19.3.4. Mazdutide / LY3305677/ IBI-362 Sales Forecast
- 19.3.5. Orforglipron / LY3502970 Sales Forecast
- 19.3.6. PB-119 / PEG-exenatide / Polyethylene glycol exenatide Sales Forecast
- 19.3.7. Retatrutide / LY3437943 Sales Forecast
- 19.3.8. Semaglutide Oral Sales Forecast
- 19.3.9. Semaglutide Subcutaneous Sales Forecast
- 19.3.10. Survodutide / BI 456906 Sales Forecast
- 19.3.11. XW003 / Ecnoglutide Sales Forecast
- 19.3.12. YN011-isupaglutide Sales Forecast
20 GLP-1 MARKET, BY LEADING DRUG DEVELOPERS
- 20.1. Chapter Overview
- 20.2. GLP-1 Market: Distribution by Leading Drug Developers, 2020 (USD Million)
- 20.3. GLP-1 Market: Distribution by Leading Drug Developers, 2024 (USD Million)
- 20.4. GLP-1 Market: Distribution by Leading Drug Developers, 2035 (USD Million)
21 APPENDIX 1: TABULATED DATA
22 APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS