市場調査レポート
商品コード
1488618
ベタメタゾンリン酸エステルナトリウム市場:形態別、純度別、適応疾患別、地域別、機会、予測、2017年~2031年Betamethasone Sodium Phosphate Market Assessment, By Form, By Purity, By Disease Indication, By Region, Opportunities and Forecast, 2017-2031F |
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ベタメタゾンリン酸エステルナトリウム市場:形態別、純度別、適応疾患別、地域別、機会、予測、2017年~2031年 |
出版日: 2024年06月05日
発行: Market Xcel - Markets and Data
ページ情報: 英文 233 Pages
納期: 3~5営業日
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世界のベタメタゾンリン酸エステルナトリウムの市場規模は、予測期間の2024年~2031年に6.51%のCAGRで拡大し、2023年の6億720万米ドルから2031年には10億567万米ドルに成長すると予測されています。市場の成長は、関節炎とアレルギーの有病率の上昇に起因しています。
世界のベタメタゾンリン酸エステルナトリウム市場の需要は、関節や腱の問題、関節炎、皮膚の問題など、さまざまな健康状態の有病率の上昇により増加しています。ベタメタゾンリン酸エステルナトリウムは、このような症状を治療するための注射剤として一般的に使用されています。ベタメタゾンはNF-Kappa Bのような炎症性転写因子とともに脱皮および好中球のアポトーシスを阻害し、ホスホリパーゼA2を阻害してアラキドン酸誘導体の形成を減少させます。ベタメタゾンなどのコルチコステロイドは、ゲノム経路と非ゲノム経路の両方を通して作用します。非ゲノム経路は、既存のセカンドメッセンジャーや膜結合レセプターを利用することにより、単球活性、T細胞、血小板を調節し、より速い反応を引き起こすことができます。一方、ゲノム経路は反応が遅く、グルココルチコイドがグルココルチコイド受容体を活性化し、チロシンアミノトランスフェラーゼ(TAT)、IL-1受容体拮抗薬、ホスホエノールピルビン酸カルボキシキナーゼ(PEPCK)などの様々な抗炎症遺伝子の転写を可能にする下流効果を開始した後にのみ起こります。
様々なタイプの関節炎患者の増加は、市場に有利な成長機会をもたらしています。例えば、米国疾病予防管理センターは、2019年~2021年に米国の成人(18歳から44歳まで)の約5.4%が関節炎を報告していると推定しています。関節炎の症例数の増加は、急性痛風性関節炎、関節リウマチ、急性非特異的腱鞘炎、変形性関節症の滑膜炎、上顆炎、急性・亜急性滑液包炎の患者に、ベタメタゾン酢酸エステル注射用懸濁液と組み合わせて短期間関節内に投与されるため、ベタメタゾンナトリウムリン酸塩の必要性を押し上げています。そのため、ベタメタゾンリン酸エステルナトリウムの需要が高まり、市場の拡大が加速しています。
当レポートでは、世界のベタメタゾンリン酸エステルナトリウム市場について調査し、市場の概要とともに、形態別、純度別、適応疾患別、地域別動向、および市場に参入する企業のプロファイルなどを提供しています。
The global betamethasone sodium phosphate market is projected to witness a CAGR of 6.51% during the forecast period 2024-2031, growing from USD 607.2 million in 2023 to USD 1005.67 million in 2031F. The market's growth is attributed to the increasing prevalence of arthritis and allergies.
The global betamethasone sodium phosphate market demand is rising owing to the increasing prevalence of various health conditions, including joint and tendon problems, arthritis, and skin problems. Betamethasone sodium phosphate is commonly used for injections to treat such conditions. It inhibits demargination and neutrophil apoptosis along with inflammatory transcription factors such as NF-Kappa B. It inhibits phospholipase A2, resulting in reduced formation of arachidonic acid derivatives. Corticosteroids such as betamethasone can act through both genomic and non-genomic pathways. The nongenomic pathways can elicit a faster response by modulating monocyte activity, T-cells, and platelets through the utilization of existing second messengers and membrane-bound receptors. Whereas the genomic pathways are slower and occur only after the glucocorticoids activate the glucocorticoid receptors, initiating the downstream effects that allows the transcription of various anti-inflammatory genes such as tyrosine amino transferase (TAT), IL-1-receptor antagonist, and phosphoenolpyruvate carboxykinase (PEPCK).
The rising cases of different types of arthritis are providing lucrative growth opportunities to the market. For instance, the Centre for Disease Control and Prevention estimates that approximately 5.4% of the adults (from age 18 to 44 years) in the United States have reported arthritis from 2019-2021. The increase in number of cases of arthritis is boosting the requirement for betamethasone sodium phosphate as it is administered intra-articularly in combination with betamethasone acetate injectable suspension for short term in patients with acute gouty arthritis, rheumatoid arthritis, acute nonspecific tenosynovitis, synovitis of osteoarthritis, epicondylitis, and acute and subacute bursitis. Thus, propelling the demand for betamethasone sodium phosphate and augmenting the expansion of the market.
Rising Requirement for Betamethasone Sodium Phosphate Injections Boosts Market Growth
Betamethasone sodium phosphate injections are steroid drugs used for treating various conditions associated with inflammation, including Crohn's disease, arthritis, ulcerative colitis, allergies, and asthma. The increasing prevalence of asthma is propelling the requirement for these injections. For instance, the American College of Allergy, Asthma and Immunology estimates that 7.7% of Americans (24.9 million individuals) suffered from asthma 2023. Of these, approximately 4.6 million are children and 20.2 million are adults. Injections are used for treating different types of disorders, including issues related to the nervous system, blood, liver, skin, and eye. The active pharmaceutical ingredient used in these injections is betamethasone sodium phosphate. Thus, bolstering the demand for the product and aiding the market expansion.
These injections are generally administered when the patient cannot consume the oral form of the medication. They are given to pregnant women who are at risk of delivering preterm to reduce the risk of development of breathing problems in the fetus. Furthermore, betamethasone is a moderately potent glucocorticoid steroid with immunosuppressive and anti-inflammatory properties. Unlike other drugs that have these properties, betamethasone is not responsible for causing the retention of water. It is sometimes used in conjunction with antihistamine to reduce irritation. Thus augmenting the requirement for these injections and boosting the global betamethasone sodium phosphate market demand.
Rising Cases of Rheumatoid Arthritis Facilitate Market Expansion
The rise in the number of cases of rheumatoid arthritis is positively influencing the expansion of the market. The Center for Disease Control and Prevention estimated that approximately one in four or 26% of adults aged 45-64 have arthritis. The increase supports the expansion of the market as betamethasone sodium phosphate finds applications in various medications that are used to treat inflammation associated with rheumatoid arthritis. Betamethasone sodium phosphate encapsulated in poly (D, L- glycolic/ lactic acid) nanoparticles works effectively in the case of rheumatoid arthritis. They aid in decreasing soft tissue swelling and paw inflammation and relieve inflammatory response by decreasing the number of inflammatory cells in the joints. Thus, this propels the requirement for betamethasone sodium phosphate to manage the inflammation caused by rheumatoid arthritis and augment the market's growth.
North America Accounts for a Significant Share of the Market
The strong presence of various leading market players, the rising requirement for betamethasone sodium phosphate, owing to the increasing prevalence of various health conditions, such as arthritis and allergic disorders, and rising investments by major research institutions towards research activities are the factors contributing towards the dominance of North America in global betamethasone sodium phosphate market. For instance, the OrthoCarolina Research Institute, Inc., United States, is conducting an interventional study for determining if the corticosteroid injection (betamethasone) modifies the course of De Quervain's Tenosynovitis in comparison to a toradol injection (Ketorolac). The study is estimated to conclude in December 2024. Rise in number of such studies will augment the demand for betamethasone sodium phosphate as they will aid researchers and scientists in determining the safety and efficacy of the medications derived from the chemical. Moreover, the increasing prevalence of asthma in various countries in North America is further boosting the requirement for betamethasone sodium phosphate.
Rising Demand for Solid Form of Betamethasone Sodium Phosphate Boosts Market Size
The increasing requirement for solid betamethasone sodium phosphate can be attributed to various product benefits, including ease of handling. The cost efficiency offered by the product due to easy transportation and distribution further augment the popularity of solid form of betamethasone sodium phosphate. Additionally, they are preferred by the pharmaceutical industry for formulating injections and tablets. The pharma industry's rapid expansion due to the increasing prevalence of various diseases is further propelling the demand for betamethasone sodium phosphate. The European Federation of Pharmaceutical Industries and Association estimates that in 2021, Europe accounted for 23.4% of the world pharmaceutical sales whereas North America accounted for 49.1%. Thus, it supports the expansion of the pharmaceutical industry in various regions and boosts the demand for various pharma products, including those that contain betamethasone sodium phosphate, augmenting the expansion of the market.
Betamethasone Sodium Phosphate with More than 99% Purity Dominates Market Share
The rising requirement for betamethasone sodium phosphate with more than 99% purity can be attributed to the growing prevalence of various conditions that cause inflammation. Betamethasone sodium phosphate binds to the intracellular glucocorticoid receptors and later binds to the DNA to modify gene expression. The disodium salt of 21-phosphate ester of betamethasone has anti-inflammatory, metabolic, and immunosuppressive actions. It inhibits the synthesis of various inflammatory mediators and induces the synthesis of anti-inflammatory proteins. As a result, an overall reduction in autoimmune reactions and chronic inflammation is witnessed.
Due to these properties of betamethasone sodium phosphate, the demand for the chemical with more than 99% purity is increasing from the pharmaceutical sector, bolstering the segment's expansion. Additionally, the rapid expansion of the pharmaceutical industry in various regions across the globe is further providing lucrative growth opportunities to the market. For instance, Invest India estimates that the pharmaceutical industry in the country will reach a value of USD 130 billion by 2030. The growth of the pharma industry will propel the requirement for betamethasone sodium phosphate with more than 99% purity and provide lucrative growth opportunities to the market.
Future Market Scenario (2024 - 2031F)
The rising efforts by various leading players of global betamethasone sodium phosphate market and research institutions are expected to evaluate the effects of betamethasone sodium phosphate for treating various conditions will provide lucrative growth opportunities to the market. For instance, Thammasat University, Thailand, is conducting an interventional study to compare the efficacy of intra-articular corticosteroid injection of Triamcinolone acetonide and Betamethasone (Diprospan) for treating knee osteoarthritis. The eligibility criteria for patient selection includes symptomatic primary knee osteoarthritis. The study is expected to conclude in June 2024. Increasing investments towards such studies will boost the demand for betamethasone sodium phosphate over the forecast period. Furthermore, the expansion of the market will also be supported by the increase in cases of arthritis in various regions across the globe and rising utilization of betamethasone sodium phosphate for treating inflammation and severe allergies, among others.
Key Players Landscape and Outlook
The increase in mergers, acquisitions, and collaborations between the leading API manufacturers is positively influencing the expansion of global betamethasone sodium phosphate market. Various leading players in the market are actively investing in enhancing their manufacturing facilities owing to the rising requirement for betamethasone sodium phosphate due to the increasing prevalence of arthritis and allergies, among others.
All segments will be provided for all regions and countries covered
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work