市場調査レポート
商品コード
1447738
ワクチンアジュバント市場の評価:製品タイプ・投与経路・疾患タイプ・用途・地域別の機会および予測 (2017~2031年)Vaccine Adjuvants Market Assessment, By Product Type, By Route of Administration, Disease Type, By Application, By Region, Opportunities and Forecast, 2017-2031F |
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ワクチンアジュバント市場の評価:製品タイプ・投与経路・疾患タイプ・用途・地域別の機会および予測 (2017~2031年) |
出版日: 2024年03月11日
発行: Market Xcel - Markets and Data
ページ情報: 英文 223 Pages
納期: 3~5営業日
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世界のワクチンアジュバントの市場規模は、2023年の13億3,000万米ドルから、2024年から2031年の予測期間中は9.95%のCAGRで推移し、2031年には28億4,000万米ドルの規模に成長すると予測されています。
世界のワクチンアジュバント市場は、いくつかの重要な要因によって大きな成長を遂げています。感染症の流行がワクチン需要の増加につながり、市場拡大を後押ししています。バイオテクノロジーの技術的進歩も市場を前進させる上で重要な役割を果たしています。さらに、R&D活動に対する政府の資金援助や投資の増加がこの成長軌道に拍車をかけています。主要参入企業間の戦略的提携や協力も市場拡大に寄与する重要な要因となっています。
ワクチン、バイオ医薬品、治療薬に対する需要の高まり
これまで以上に多くのワクチン、バイオ医薬品、治療薬が必要とされています。COVID-19によって、ワクチンは現在も将来もさらに不可欠なものとなっています。ワクチンアジュバントはワクチンに不可欠な成分であり、ワクチンの使用が増えれば、結果的にワクチンアジュバントの需要も高まることになります。医療分野では、バイオ医薬品、遺伝子治療薬、細胞治療薬がますます普及しています。人口の増加、疾病の拡大、パンデミックの脅威、COVID後の対応策、人々の意識の高まりなどの要因が、今後数年間のワクチンアジュバント需要を牽引しています。
感染症の流行拡大
感染症の流行は、気候変動、急速な都市化、土地利用パターンの変化など、いくつかの要因によって増加しています。これらの要因は、新しい疾病の出現、古い疾病の再出現、既存の疾病の蔓延につながります。医療の向上や世界的な旅行といった技術的な変化も感染症の蔓延に寄与しています。さらに、人口増加や移民などの人口動態の変化も、疾病の発生リスクを高める可能性があります。感染症の流行が増加するにつれ、ワクチンの需要も高まります。世界保健機関 (WHO) は、世界の年間死亡者数の約3分の1が感染症によるものと推定しており、急性呼吸器感染症、消化器感染症、結核、マラリアが世界の疾病と死亡の大半を引き起こしています。
炭水化物アジュバントが急成長
炭水化物ベースのアジュバントはワクチン開発においてますます人気が高まっています。これらは安全で身体に適合すると考えられており、免疫反応を誘発し制御することができます。これらのアジュバントは、サブユニットワクチンと併用することで、身体の免疫反応を高め、ワクチンをより効果的にするのに役立ちます。天然および合成の炭水化物がアジュバントとして臨床試験でテストされ、ヒト用ワクチンへの使用が承認されたものもあります。炭水化物アジュバントには、体への適合性が高い、忍容性が高い、安全性が高いなど、いくつかの利点があります。これらの点から、ワクチンのアジュバントとして有望視されています。
当レポートでは、世界のワクチンアジュバントの市場を調査し、市場の定義と概要、市場規模の推移・予測、各種区分・地域別の詳細分析、産業構造、市場成長への影響因子の分析、ケーススタディ、競合情勢、主要企業のプロファイルなどをまとめています。
Global vaccine adjuvants market is projected to witness a CAGR of 9.95% during the forecast period 2024-2031F, growing from USD 1.33 billion in 2023 to USD 2.84 billion in 2031. The global vaccine adjuvants market is witnessing substantial growth driven by several key factors. The increasing prevalence of infectious diseases has led to a rising demand for vaccines, propelling market expansion. Technological advancements in biotechnology are also playing a significant role in driving the market forward. Moreover, increased government funding and investments in research and development activities are fueling this growth trajectory. Strategic collaborations and partnerships among key industry players are also acting as crucial factors contributing to the market's expansion. Vaccine adjuvants enhance immunogenicity, leading to more effective vaccines with reduced antigen content, crucial for mass vaccination campaigns. However, challenges like side effects and toxicity associated with some adjuvants, particularly aluminum adjuvants, which can cause local injection site reactions and allergic responses hinder the market. Additionally, the concern for public health and safety may limit the adoption of certain adjuvants if they pose risks or potential harm to individuals receiving them.
In October 2023, after careful evaluation, the World Health Organization (WHO) approved the use of the R21/Matrix-M malaria vaccine. Developed by the University of Oxford, the Serum Institute of India, and leveraging Novavax's adjuvant technology, the vaccine has met strict standards for safety, quality, and effectiveness. Experts from the WHO's independent advisory groups, SAGE and MPAG, conducted a thorough review and found that the vaccine is effective and safe. Clinical trials in various regions with different malaria transmission rates have demonstrated its efficacy.
Growing Demand for Vaccines, Biopharmaceuticals, and Therapy Products
More vaccines, biopharmaceuticals, and therapies are needed than ever before. COVID-19 has made vaccines even more essential, both now and in the future. Vaccine adjuvants are essential components of vaccines and increasing the use of vaccines will ultimately enhance the demand for vaccine adjuvants. In the medical sector, biopharmaceuticals, gene therapies, and cell therapies are becoming more and more popular. Factors, such as population growth, escalating disease prevalence, pandemic threats, post-COVID readiness measures, and heightened public awareness, are driving the demand for vaccine adjuvants in the upcoming years.
As per the WHO report published in May 2023, between the years 2019 and 2021, a significant increase in the consumption of vaccines has been observed. The adult vaccines segment grew by 15%, pediatric vaccines registered a growth of 8%, and vaccines used for adolescents registered a growth of 7%. This data does not consider COVID-19 vaccines, but still, a significant change in demand can be seen.
Growing Prevalence of Infectious Diseases
The prevalence of infectious diseases is increasing due to several factors, including climate change, rapid urbanization, and changes in land-use patterns. These factors contribute to the emergence of new diseases, the re-emergence of old diseases, and the spread of existing diseases. Technological changes, such as improved health care and global travel, also contribute to the spread of infectious diseases. Additionally, demographic changes, such as population growth and migration, can increase the risk of disease emergence. As the prevalence of infectious diseases increases, the demand for vaccines rises, subsequently enhancing the market demand for vaccine adjuvants as they are essential components of the finished vaccines. The World Health Organization estimates that approximately one-third of annual deaths worldwide are attributed to infectious diseases, with acute respiratory tract infections, gastrointestinal infections, tuberculosis, and malaria causing most of the illnesses and mortality worldwide.
For instance, as per the data published by Worldometers, over 703 million COVID-19 cases were reported till February 2024, along with 69 million deaths reported. COVID-19 has been the most contagious and lethal infectious disease in recent times.
Carbohydrate-based Adjuvants are Fastest Growing
Carbohydrate-based adjuvants are becoming increasingly popular in vaccine development. They are considered safe and compatible with the body, and they can trigger and control immune responses. These adjuvants help make vaccines more effective by boosting the body's immune response when used with subunit vaccines. Natural and synthetic carbohydrates have been tested as adjuvants in clinical trials, and some have been approved for use in human vaccines. Carbohydrate-based adjuvants offer several advantages, including being highly compatible with the body, well-tolerated, and having a good safety record. These factors make them promising candidates for use as adjuvants in vaccines.
Infectious Disease to be the Leading Disease Type
The infectious disease segment is expected to be the leading disease type for utilizing vaccines for treatment purposes. A variety of vaccines are available in the market for infectious diseases like hepatitis, polio, tetanus, and influenza. Vaccines are highly effective in infectious diseases because they provide long-lasting immunity, protect against severe illness and death, and reduce the spread of the disease within a population. Vaccines work by imitating an infection, engaging the body's natural immune response, and providing protection without the dangers of a full-blown infection. Vaccines are more effective in infectious diseases because they target specific pathogens, and their development is based on the characteristics of the pathogen, such as antigenic stability, serotype, and the presence of diagnostic tests or clinical criteria for measuring disease burden.
In May 2023, GSK announced the US Food and Drug Administration's approval for its Arexvy (respiratory syncytial virus vaccine, adjuvanted) meant for the prevention of lower respiratory tract disease (LRTD) caused due to respiratory syncytial virus (RSV) in patients of 60 years of age and older. Arexvy is the world's first RSV vaccine for elders to be approved.
North America to be the Dominating Region
North America's leadership in the vaccine adjuvant market stems from several key reasons. Governments are investing heavily in research, and companies within the industry are partnering to achieve breakthroughs. The region's healthcare system is well-developed, with a focus on preventive care. This encourages the use of adjuvanted vaccines, which make vaccines more effective and are thoroughly tested before being approved. This reflects the region's commitment to preventive healthcare measures. Additionally, the region's strong regulatory framework ensures the safety and efficacy of adjuvanted vaccines, further boosting market confidence. US FDA considers vaccine adjuvant as a part of the vaccine and not as a separate entity, thus separate approval for vaccine adjuvant is not required.
Future Market Scenario
The future of vaccine adjuvants is expected to focus on the development of new, more effective, and safer adjuvants. Research is being conducted to create adjuvants that can enhance the immune response to vaccines, particularly for subunit vaccines, which are often less effective at generating a robust immune response. New adjuvants are being developed from natural resources and synthetic components, to improve safety and protective efficacy. Technologies, such as nanotechnologies and molecular biology, are being used to improve vaccine efficacy, and adjuvants are being designed to stimulate immune responses in a more targeted manner. Additionally, systems vaccinology approaches are being used to assess and characterize new adjuvant systems, which may help in the rational design of vaccines in the future.
Key Players Landscape and Outlook
Brenntag Biosector A/S, OZ Biosciences, Agenus, Inc., Spectrum Pharmaceuticals, Inc., SEPPIC, Inc., Novavax, Inc., and MPV Technologies are some of the key players in the vaccine adjuvants market. These companies are actively involved in the production and advancement of vaccine adjuvants, contributing to the growth and innovation within the industry. The market is competitive, with a focus on enhancing vaccine efficacy, reducing production costs, and developing safer and more effective vaccines through ongoing advancements in technology and formulations.
In February 2024, DTRA's JSTO awarded a USD 31 million, 5-year contract to Ginkgo Bioworks and SaponiQx through the MCDC program to develop cutting-edge vaccine adjuvants. Ginkgo, specializing in cell programming and biosecurity, and SaponiQx, with its innovative adjuvant platform, have been collaborating on this project since 2021.
All segments will be provided for all regions and countries covered
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.