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市場調査レポート
商品コード
1335921
網膜生物製剤の世界市場規模・シェア・産業動向分析レポート:適応症別、薬剤クラス別、流通チャネル別、地域別展望・予測、2023年~2030年Global Retinal Biologics Market Size, Share & Industry Trends Analysis Report By Indication, By Drug Class, By Distribution Channel, By Regional Outlook and Forecast, 2023 - 2030 |
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網膜生物製剤の世界市場規模・シェア・産業動向分析レポート:適応症別、薬剤クラス別、流通チャネル別、地域別展望・予測、2023年~2030年 |
出版日: 2023年07月31日
発行: KBV Research
ページ情報: 英文 229 Pages
納期: 即納可能
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網膜生物製剤市場規模は2030年までに207億米ドルに達すると予測され、予測期間中のCAGRは5.4%の市場成長率で上昇します。
しかし、医薬品の承認には、多くの費用のかかる規制当局の承認や調査段階が必要です。医薬品の承認プロセスには、約4段階の臨床試験を含む、規制当局の審査が数段階含まれます。臨床試験段階には多額の投資が必要なため、失敗した研究のコストは高いです。例えば、フォーブス誌の記事によると、ある医薬品メーカーは、上市されるまでに1つの治療法に約3億5,000万米ドルを投資しています。待ち時間が長いと、こうした生産者にもコストがかかり、市場拡大の妨げになります。さらに、COVID-19の大流行によって、ヘルスケア業界のワークフローは世界的に影響を受けた。ヘルスケア・セクターのいくつかの地域や他のいくつかの産業が、病気のために一時的に閉鎖されました。COVID-19主導の世界の景気減速は、2020年の市場の落ち込みを引き起こしました。パンデミックはまた、製薬、ヘルスケア、産業部門を含むいくつかのエンドユーザー業界のサプライチェーンの低下を引き起こしました。このため市場が限定され、革新的な医薬品の発売にも影響が出ました。
適応症の展望
適応症に基づき、市場は黄斑変性症、糖尿病網膜症、その他に分類されます。黄斑変性症セグメントは、2022年の市場で最も高い収益シェアを獲得しました。網膜生物製剤は、網膜の炎症を抑え、異常な血管の形成を抑制することで、黄斑変性症患者の視力を維持し、さらなる視力低下を食い止めることができます。生物学的製剤を早期に効果的に使用することで、視力が安定したり、改善したりすることもあります。一部の網膜生物学的製剤は徐放性製剤であるため、注射や治療の頻度を減らすことができます。
薬剤クラス別展望
薬剤クラス別では、市場はVEGF-A拮抗薬とその他に区分されます。その他セグメントは2022年の市場で大きな収益シェアを記録しました。その他のセグメントには、主にTNF-αから開発された生物製剤が含まれます。炎症性サイトカインである腫瘍壊死因子α(TNF-α)は、マクロファージやT細胞によって生成されます。炎症とアポトーシスの両者において重要です。TNF-αは、眼における炎症性疾患、浮腫性疾患、新生血管疾患、神経変性疾患の発症に関与していると考えられています。
流通チャネルの展望
流通チャネルに基づき、市場は病院薬局、オンライン薬局、小売薬局に分けられます。オンライン薬局セグメントは、2022年の市場でかなりの成長率を確保しました。このセグメントの成長に影響を与える主な要因の1つは、様々な眼疾患の治療のために眼科クリニックを訪れる患者数の増加です。先進国でも発展途上国でも、インターネットを利用する人が増えており、患者はオンラインで医薬品を購入することを選ぶようになっています。
地域別展望
地域別に見ると、市場は北米、欧州、アジア太平洋、LAMEAで分析されます。北米地域は、2022年の市場において最大の収益シェアを記録しました。Bayer AGやNovartis AGをはじめとする数多くの大手企業の存在や、網膜生物製剤の生産における発展が、市場拡大の原動力となっています。さらに、網膜生物学的製剤へのアクセスが容易であること、早期発見・早期治療の重要性に対する社会的認知が高まっていることも、この地域の市場拡大を後押しする主な要因となっています。さらに、病院、診療所、研究機関の強力なネットワークがヘルスケア・インフラを構成しています。このインフラは網膜生物学の創出、利用、研究を支援しています。
List of Figures
The Global Retinal Biologics Market size is expected to reach $20.7 billion by 2030, rising at a market growth of 5.4% CAGR during the forecast period.
As people age, a variety of diseases and issues can arise. The senior population is more at risk of the age-related progression of AMD disease thus, the macular degeneration segment will register around 60% share in the market by 2030. For example, By 2050, there will be about 1.5 billion people on the planet, a rise of more than three times the current population. Additionally, it is anticipated that by this time, 16.0% of people will be over the age of 60 worldwide. One out of every six people will be 65 or older by the middle of the twenty-first century. The global increase in the number and prevalence of older people is known as the "population aging phenomenon." In 2019, there were 703 million people worldwide who were 65 or older. People 65 and over made up 9% more of the population in 2019 than they did in 2018. Some of the factors impacting the market Technological advances aiding in the development of retinal biologics, Rising prevalence of retinal and eye issues, and longer time periods for drug approval.
Retinal biologic products have undergone technological breakthroughs that have improved their safety and effectiveness profiles, which has led to a rise in patient uptake across the globe. Significant R&D expenditures and business partnerships among market players are advantageous for developing retinal biology. The technical advances place a strong focus on research and development (R&D) pertaining to retinal gene treatments conducted by various institutes, biologics firms, and innovative product launches by key players in the form of implants and biologics. Additionally, Because of the increasing number of initiatives taken by various healthcare organizations, governmental entities, and industry actors, there is a greater awareness among the general public about ocular problems, which is leading to a higher diagnostic and treatment rate in the population. Concern regarding diabetic retinopathy has grown as more adults with type I and type II diabetes are losing their vision as a result of the disease. Thus, technological improvements in retinal biologics products and increasing prevalence of ocular issues will augment the expansion of the market in the coming years.
However, a number of pricey regulatory approvals and research phases are necessary for drug approval. The process of approving a medicine involves several phases of regulatory agency screening, including about four clinical trial steps. The costs of failing studies are high because clinical trial phases need large investments. For instance, according to a Forbes article, a medication producer invests approximately $350 million in each therapy before it is put on the market. Long wait times also cost these producers money, which hinders the expansion of the market. Furthermore, workflows in the healthcare industry were affected globally by the COVID-19 pandemic. Several areas of the healthcare sector, as well as several other industries, temporarily closed their doors due to the sickness. The COVID-19-led worldwide economic slowdown caused a drop in the market in 2020. The pandemic also caused supply chains in several end-user industries to fall, including the pharmaceutical, healthcare, and industrial sectors. This limited the market and impacted the release of innovative medicines.
Indication Outlook
Based on indication, the market is categorized into macular degeneration, diabetic retinopathy, and others. The macular degeneration segment procured the highest revenue share in the market in 2022. Retinal biologics can help maintain eyesight and stop additional vision loss in people with macular degeneration by lowering inflammation in the retina and limiting the formation of aberrant blood vessels. Biologics used early and effectively can sometimes stabilize or even improve vision. The frequency of injections or treatments is decreased by some retinal biologics' extended-release formulations.
Drug Class Outlook
On the basis of drug class, the market is segmented into VEGF-A antagonist and others. The others segment recorded a significant revenue share in the market in 2022. The other segment mostly includes biologics developed from TNF-α. The pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-α) is generated by macrophages and T-cells. It is significant in both inflammation and apoptosis. TNF-α is considered part of developing inflammatory, edematous, neovascular, and neurodegenerative illnesses in the eye.
Distribution Channel Outlook
Based on distribution channel, the market is divided into hospital pharmacy, online pharmacy, and retail pharmacy. The online pharmacy segment procured a considerable growth rate in the market in 2022. One of the key factors influencing the segment's growth is the increasing number of patients visiting ophthalmology clinics for the treatment of various eye conditions. In both established and developing nations, there are more and more people using the internet, and patients are increasingly choosing to buy their drugs online.
Regional Outlook
Region-wise, the market is analyzed across North America, Europe, Asia Pacific, and LAMEA. The North America region recorded the largest revenue share in the market in 2022. The existence of numerous significant players, including Bayer AG, and Novartis AG, as well as developments in the production of retinal biologics, are driving the market's expansion. Additionally, easier access to retinal biologics medications and greater public awareness of the importance of early detection and treatment are key factors driving market expansion in this region. In addition, a strong network of hospitals, clinics, and research institutions makes up the healthcare infrastructure. This infrastructure aids in the creation, use, and study of retinal biology.
Strategies deployed in Retinal Biologics Market
Jul-2023: Bausch + Lomb acquired the Blink over-the-counter (OTC) line of eye drops from Johnson & Johnson Vision. The acquisition expanded the former company's portfolio of OTC eye care products and the addition would enable the company to provide enhanced convenience to consumers.
May-2023: Bausch + Lomb, the eyecare division of Bausch Health, received approval from the U.S. Food and Drug Administration for Miebo drops for dry eye disease. The medication fills a sizable gap in patient care as it is the only FDA-approved treatment to specifically target tear evaporation.
Feb-2023: AbbVie extended its collaboration with Capsida Biotherapeutics, a fully integrated next-generation gene therapy platform company, for developing genetic medicines for eye problems. Capsida's cutting-edge adeno-associated virus (AAV) engineering platform and manufacturing expertise will be integrated with AbbVie's comprehensive capabilities to identify and advance three candidates.
Aug-2022: Bausch + Lomb partnered with Munich Surgical Planning (MSI), a subsidiary of Heidelberg Engineering. To meet the rising demand for digital microscopy, this partnership aimed to bring together Bausch + Lomb's surgical expertise in the cataract, refractive, and vitreoretinal space with MSI's visualization and image guidance expertise, including an integrated high-speed SSOCT powered by Heidelberg Engineering.
Jul-2022: Roche came into partnership with Avista Therapeutics, a company focused on developing innovative gene therapies for retinal diseases, for developing novel AAV gene therapy vectors for eyes. The partnership aimed to use Avista's single-cell adeno-associated virus engineering (scAAVengr) platform technology to create intravitreal AAV capsids that fit a capsid profile specified by Roche. Moreover, Roche is in charge of conducting preclinical, clinical, and commercialization activities for gene therapy programs using these novel capsids, which is different from Avista's internal pipeline. Roche will also have the right to evaluate and license novel capsids from Avista.
Feb-2022: Roche received the U.S. Food and Drug Administration approval for Vabysmo (faricimab-svoa) for the treatment of neovascular Diabetic Macular Edema (DME) and Age-related Macular Degeneration (nAMD). Vabysmo neutralizes the disease-related proteins angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A), which are associated with a range of retinal disorders that can impair vision.
Jan-2022: AbbVie got the U.S. Food and Drug Administration (FDA) approval for RINVOQ® (upadacitinib). This medication is indicated for the treatment of moderate to severe atopic dermatitis in children 12 years of age and above and adults.
Dec-2021: Novartis signed an agreement to acquire Gyroscope Therapeutics, a clinical-stage gene therapy company. Through this acquisition, Novartis would achieve access to the prior guide experimental gene treatment, GT005.
Mar-2021: Roche signed a collaboration and licensing agreement with SemaThera, a company focused on creating novel therapies for retinopathies. The partnership was focused on creating SemaThera's exciting new class of biologicals for the management of ischemic retinal disorders, such as diabetic retinopathy.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Novartis AG, Amgen, Inc., AbbVie, Inc., Bayer AG, Regeneron Pharmaceuticals, Inc., Santen Pharmaceutical Co., Ltd., Bausch Health Companies, Inc., F. Hoffmann-La Roche Ltd., MeiraGTx Holdings plc and Oxurion NV.
Market Segments covered in the Report:
By Indication
By Drug Class
By Distribution Channel
By Geography
Companies Profiled
Unique Offerings from KBV Research