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市場調査レポート
商品コード
1702077
デジタルPCR市場レポート:製品タイプ、技術、用途、地域別、2025年~2033年Digital PCR Market Report by Product Type, Technology, Application, and Region 2025-2033 |
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デジタルPCR市場レポート:製品タイプ、技術、用途、地域別、2025年~2033年 |
出版日: 2025年04月01日
発行: IMARC
ページ情報: 英文 135 Pages
納期: 2~3営業日
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デジタルPCR市場の世界市場規模は2024年に52億米ドルに達しました。今後、IMARC Groupは、市場は2033年までに111億米ドルに達し、2025-2033年の成長率(CAGR)は8.88%になると予測しています。核酸定性の精度向上、リキッドバイオプシー需要の高まり、ゲノム研究の著しい進歩、バイオテクノロジーと製薬産業の拡大、広範な研究投資活動が市場を推進する主な要因の一部です。
デジタルPCR(デジタルポリメラーゼ連鎖反応)は、様々な用途でDNAやRNAなどの核酸を定量・分析するために使用される高精度で高度な分子生物学技術です。単一のエンドポイント測定しか提供しない従来のPCRとは異なり、デジタルPCRはサンプルを物理的またはデジタル的に何千もの小さな個々の反応に分割します。これは標的核酸の絶対定量を可能にし、比類のない感度と精度を提供します。デジタルPCRはゲノミクス、臨床診断、環境モニタリングなどの分野で役立っています。まれな変異の検出、遺伝子発現の定量化、ウイルス量の評価などの能力により、遺伝性疾患の理解、治療反応のモニタリング、微生物群集の研究において貴重なツールとなっています。その定量的な性質と阻害剤に対する最小限の感受性により、重要なアプリケーションにおいて高い信頼性があります。
デジタルPCRは核酸定量において優れた精度と感度を提供し、ゲノミクス、診断、製薬研究において不可欠なツールとなっています。さらに、がんの検出とモニタリングのためのリキッドバイオプシーが人気を集めています。血液やその他の体液中のまれな変異やコピー数の変動を検出するdPCRの能力は、この重要な分野での採用を後押ししています。この他にも、dPCRは感染症や遺伝性疾患の診断、ウイルス量のモニタリングにおいて極めて重要な役割を果たしています。これは、COVID-19のパンデミックのような世界の健康問題において特に重要です。このほか、バイオテクノロジーや製薬の分野では、研究開発のための堅牢なツールが絶えず求められています。dPCRは、医薬品開発やバイオ製造プロセスにおける正確な定量を可能にすることで、このニーズに応えています。これと同様に、水や土壌中の病原体の検出を含む環境モニタリングは、低レベルの汚染物質の検出における精度と信頼性から、dPCRに依存しています。dPCRは精密な遺伝子解析を容易にし、画期的な発見に貢献しています。
核酸定量における精度の向上
デジタルPCRは、核酸の定量において比類ないレベルの精度を提供します。相対測定に頼る従来の定量PCR(qPCR)とは異なり、dPCRは絶対定量を提供します。この精度は、サンプルを何千もの別々の反応に分割し、存在する標的分子の数を効果的にカウントすることによって達成されます。このレベルの精度は、がんにおける稀な遺伝子変異の検出、診断検査の信頼性の確保、感染症におけるウイルス量の変化の追跡など、様々なアプリケーションにおいて不可欠です。
リキッドバイオプシーに対する需要の高まり
血液やその他の体液を分析してがん関連のバイオマーカーを調べるリキッドバイオプシーは、がんの早期発見や治療モニタリングにおいてますます重要になってきています。デジタルPCRの感度は、微量の変異DNAまたはRNAの検出を可能にし、リキッドバイオプシーアッセイにおいて極めて重要な技術となっています。臨床医はdPCRを用いて様々ながんに関連する特定の遺伝子変異を同定し、個別化治療戦略のための貴重な情報を提供することができます。
ゲノム研究の著しい進歩
ゲノミクスの分野は、疾患の遺伝的基盤を理解し、標的療法を開発する必要性によって、進化し続けています。デジタルPCRは、科学者が遺伝子発現を正確に定量化し、稀な遺伝子変異を検出し、コピー数の変異を研究することを可能にすることによって、この研究において中心的な役割を果たしています。これらの能力は、疾患の原因となる遺伝的要因を明らかにし、潜在的な薬物標的を同定し、治療介入を最適化するために不可欠です。ゲノム研究が拡大するにつれて、遺伝子解析の精度と再現性の両方を提供するツールとしてのdPCRの需要も高まっています。
The global digital PCR market size reached USD 5.2 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 11.1 Billion by 2033, exhibiting a growth rate (CAGR) of 8.88% during 2025-2033. The increased precision in nucleic acid qualification, rising demand for liquid biopsies, significant advancements in genomic research, expanding biotechnology and pharmaceutical industries, and extensive research and investment activities are some of the major factors propelling the market.
Digital PCR, or digital polymerase chain reaction, is a highly precise and advanced molecular biology technique used for quantifying and analyzing nucleic acids, such as DNA and RNA, in various applications. Unlike traditional PCR, which provides only a single endpoint measurement, digital PCR partitions the sample into thousands of tiny individual reactions, either physically or digitally. This allows for the absolute quantification of the target nucleic acid, offering unparalleled sensitivity and accuracy. Digital PCR is instrumental in fields like genomics, clinical diagnostics, and environmental monitoring. Its ability to detect rare mutations, quantify gene expression, and assess viral loads has made it a valuable tool in understanding genetic diseases, monitoring treatment responses, and studying microbial communities. Its quantitative nature and minimal susceptibility to inhibitors make it highly reliable in critical applications.
Digital PCR offers superior accuracy and sensitivity in nucleic acid quantification, making it an indispensable tool in genomics, diagnostics, and pharmaceutical research. Additionally, liquid biopsies for cancer detection and monitoring are gaining traction. The ability of dPCR to detect rare mutations and copy number variations in blood and other bodily fluids fuels its adoption in this critical field. Other than this, dPCR plays a pivotal role in diagnosing infectious diseases, genetic disorders, and monitoring viral loads. This is particularly crucial in the context of global health concerns, such as the COVID-19 pandemic. Besides this, the biotech and pharmaceutical sectors continually demand robust tools for research and development. dPCR meets this need by enabling precise quantification in drug development and biomanufacturing processes. In line with this, environmental monitoring, including the detection of pathogens in water and soil, relies on dPCR for its accuracy and reliability in detecting low-level contaminants. Moreover, genomic research is expanding, driven by the need to understand genetic contributions to diseases and develop personalized medicine. dPCR facilitates precise genetic analysis, aiding in breakthrough discoveries.
Increased Precision in Nucleic Acid Quantification
Digital PCR offers an unparalleled level of precision in quantifying nucleic acids. Unlike traditional quantitative PCR (qPCR), which relies on relative measurements, dPCR provides absolute quantification. This precision is achieved by partitioning the sample into thousands of separate reactions, effectively counting the number of target molecules present. This level of accuracy is essential in various applications, such as detecting rare genetic mutations in cancer, ensuring the reliability of diagnostic tests, and tracking viral load changes in infectious diseases.
Rising Demand for Liquid Biopsies
Liquid biopsies, which involve analyzing blood or other bodily fluids for cancer-related biomarkers, are becoming increasingly important in early cancer detection and treatment monitoring. Digital PCR's sensitivity enables the detection of minute amounts of mutated DNA or RNA, making it a pivotal technology in liquid biopsy assays. Clinicians can use dPCR to identify specific genetic mutations associated with various cancers, providing valuable information for personalized treatment strategies.
Significant Advancements in Genomic Research
The field of genomics continues to evolve, driven by the need to understand the genetic basis of diseases and develop targeted therapies. Digital PCR plays a central role in this research by allowing scientists to precisely quantify gene expression, detect rare genetic variants, and study copy number variations. These capabilities are vital for uncovering genetic factors contributing to diseases, identifying potential drug targets, and optimizing therapeutic interventions. As genomic research expands, so does the demand for dPCR as a tool that offers both accuracy and reproducibility in genetic analysis.
Digital PCR equipment dominates the market
The pivotal role of digital PCR equipment in molecular biology and genetic research positions it as a fundamental tool in laboratories worldwide. The demand for precise nucleic acid quantification, which digital PCR equipment excels in, continues to rise across various applications, including genomics, diagnostics, and environmental monitoring. Additionally, as scientific understanding advances and the need for high-throughput and sensitive techniques grows, digital PCR equipment stands out as the preferred choice. Its ability to detect and quantify rare genetic mutations, copy number variations, and low-level viral loads has made it indispensable in fields like cancer research, infectious disease diagnostics, and monitoring of genetic disorders. Furthermore, ongoing technological advancements in digital PCR platforms, automation, and integration with other laboratory systems have made this equipment more user-friendly and efficient, driving its adoption in both research and clinical settings.
Droplet digital PCR holds the largest share in the market
Droplet digital PCR (ddPCR), combines the precision of digital PCR (dPCR) with increased throughput, making it an attractive choice for researchers and diagnosticians. This technology partitions a sample into thousands of tiny droplets, each serving as an individual reaction vessel. This parallelization significantly enhances the sensitivity and accuracy of nucleic acid quantification. Additionally, ddPCR excels in applications that require absolute quantification, especially in situations where rare mutations, copy number variations, or low-abundance targets need to be detected. Its ability to provide an absolute count of target molecules within a sample, rather than relying on relative measurements, is a significant advantage in genomics, cancer research, and clinical diagnostics. Other than this, ddPCR offers robustness in the presence of inhibitors, making it suitable for challenging sample types, such as those found in environmental monitoring or clinical specimens. This resilience to inhibitory substances enhances the reliability and versatility of technology.
Clinical diagnostics dominate the market
The ever-growing emphasis on healthcare and wellness globally has spurred an increased demand for accurate and timely diagnostic tests. As the population ages and health concerns become more prevalent, the need for early disease detection and monitoring has surged, leading to a substantial uptick in clinical diagnostic services. Furthermore, advancements in technology have played a pivotal role in enhancing the precision and speed of diagnostic procedures, making them more accessible and reliable. In addition, the COVID-19 pandemic brought to the forefront the importance of diagnostic testing, underscoring the critical role of clinical diagnostics in public health.
North America exhibits a clear dominance in the market
The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America accounted for the largest market share.
North America has a well-established and highly sophisticated healthcare infrastructure, including a robust network of clinical laboratories and research institutions. This infrastructure fosters the adoption of advanced molecular diagnostic techniques like dPCR, particularly in the United States and Canada, where healthcare expenditure is substantial. Additionally, the region is at the forefront of genomics and personalized medicine research. The demand for precise nucleic acid quantification technologies like dPCR is driven by the region's extensive genomic research initiatives and the increasing emphasis on tailoring medical treatments to individual patients. Other than this, the region has a thriving biotechnology and pharmaceutical industry that relies heavily on dPCR for drug development, clinical trials, and quality control processes. The versatility and accuracy of dPCR technology make it an essential tool in these sectors. Furthermore, North America has been quick to adopt innovative diagnostic technologies, especially in response to public health crises like the COVID-19 pandemic. The use of dPCR for virus detection and monitoring has further propelled its growth in the region.
Leading companies consistently invest in R&D to develop innovative dPCR platforms with improved sensitivity, automation, and scalability. These advancements cater to the evolving needs of researchers and clinicians across various applications. Additionally, numerous major players have established collaborations with academic institutions, research organizations, and other industry stakeholders. These partnerships facilitate the exchange of knowledge, expertise, and resources, leading to the development of cutting-edge dPCR technologies. Other than this, to address a wide range of applications, key players have expanded their product portfolios to include different dPCR platforms and consumables. This allows them to cater to diverse customer needs and preferences. Besides this, companies have pursued strategies to expand their presence in emerging markets, capitalizing on the increasing adoption of dPCR technologies in regions with growing healthcare and biotechnology sectors. In line with this, key players invest in marketing campaigns to raise awareness about the benefits of dPCR. These efforts target both existing and potential customers, highlighting the advantages of technology in research, diagnostics, and other applications.
The market research report has provided a comprehensive analysis of the competitive landscape in the market. Detailed profiles of all major companies have also been provided. Some of the key players in the market include: