mRNA合成材料の市場規模、シェア、動向分析レポート：タイプ別（キャッピング剤、ヌクレオチド、プラスミドDNA）、アプリケーション別、最終用途別、地域別、セグメント別予測、2023年～2030年

mRNA合成材料の市場成長・動向

Grand View Research, Inc.の新しいレポートによると、mRNA合成材料の世界市場規模は2030年までに33億米ドルに達すると予測されています。2023年から2030年までのCAGRは2.1%で拡大すると予測されています。市場成長の主な要因としては、mRNA技術に対する学術的・産業的関心の高まり、mRNAワクチンの優位性、研究資金の増加などが挙げられます。また、RNA技術の治療用途の増加は、予測期間中、mRNA合成材料市場に有利な機会を提供すると予測されます。

COVID-19の大流行により、感染症と戦うための効率的なワクチンを開発するためのmRNA合成材料の需要が高まっています。mRNAワクチンは、COVID-19を予防するための安全で効率的な方法です。さらに、mRNA COVID-19ワクチンに関する利点は、世界中にワクチンを迅速に提供する製薬企業の関心を呼び起こしました。例えば、2020年3月に国立アレルギー・感染症研究所と株式会社モデルナがmRNA-1273（NIAID）を相互開発しました。その結果、COVID-19のパンデミックの際にmRNAワクチンの使用量が大幅に増加しました。

さらに、Novartis、Alexion、AstraZeneca、Pfizer、Sanofi Pasteur、Shireなど、多くの大手製薬会社がmRNAベースの治療薬に取り組み始めています。例えば、2022年1月、ファイザー社とAcuitas Therapeuticsの間の開発およびオプション契約によると、ファイザー社はmRNA治療薬＆ワクチン開発のため、最大10のターゲットについてAcuitasのLNP技術のライセンスを受けるオプションを持つことになります。このため、製薬会社やバイオテクノロジー企業の間ではmRNA合成材料の採用率が高まっており、市場の成長をさらに後押ししています。

また、mRNAの翻訳は一時的なものであり、細胞のゲノムに外来物質が組み込まれることはないため、得られる細胞治療製品は、従来のアプローチで得られるものと比べて多くの利点があると言われています。その中には、許容される製造手順のもとでの製造の容易さ、オンターゲット・オフターターゲット効果による細胞毒性の低減、臨床バリデーションや規制上の取り扱いの良さといった利点があります。したがって、このような利点により、mRNA治療薬の需要が高まり、市場の成長がさらに高まると予想されます。

さらに、いくつかの疾患の治療と予防に関して、mRNAベースの技術は信じられないほど有望であることが証明されています。過去10年間における技術および科学研究の飛躍的な進歩により、mRNAは実現可能な治療オプションとなり、半減期の短さや生来の免疫原性といった使用上の問題点が解消されています。例えば、mRNA技術の進歩に伴い、新しい養子免疫療法との融合により、最先端のキメラ抗原受容体T細胞の作製など、より安全で効率的な方法が実現する可能性があります。したがって、mRNA技術の進歩は、市場成長の新たな道を開くと予測されます。

しかし、原材料の高コストが調査期間中の市場の足かせとなる可能性があります。例えば、クリーンキャップAGなどの原材料の購入価格は、両ワクチンの生産時に発生する総原材料コストの約45%を占めています。さらに、バイオテクノロジー、製薬、医療技術業界では、承認プロセスに関わる規制の枠組みが常に最も重大な抑制要因となっています。mRNA合成材料市場が大きな成長の可能性を秘めている中国やインドなどの新興国では、大規模な患者基盤の存在により、治療分野に対する効果的な規制の枠組み/ガイドラインが存在しないため、今後数年間の市場成長を阻害すると予想されます。

mRNA合成材料市場のレポートハイライト

2022年、バイオ医薬品産業および研究におけるキャッピング技術の進歩およびその応用により、キャッピング剤セグメントが40.6%の最大シェアを占めた

用途別では、ワクチン製造分野が2022年に85.30%の高シェアを獲得しました。これは、失敗しがちな細胞培養ベースの生産ルートを使用する従来のワクチンと比較して、mRNAワクチンの生産が迅速であることに起因しています。

北米は2022年に35.5%の最高収益シェアを占めました。これは、主要プレイヤーの存在、バイオテクノロジーおよび製薬企業にとって確立された商業インフラの利用可能性、および同地域における高い研究開発投資額に起因しています。

最終用途別では、バイオ医薬品分野への投資の増加やパイプラインの増加により、mRNA合成材料のニーズが高まり、2022年にはバイオ医薬品・製薬会社分野が市場を独占した

目次

第1章 調査手法と範囲

• 調査手法
• 調査の仮定
• 情報調達
  • 購入したデータベース
  • Gvrの内部データベース
  • 二次情報
  • 1次調査
• 情報またはデータ分析
  • データ分析モデル
• 市場の策定と検証

第2章 エグゼクティブサマリー

• 市場のスナップショット
• セグメントのスナップショット
• 競合情勢のスナップショット

第3章 市場変数、動向、および範囲

• 親市場分析
• 市場力学
  • 市場促進要因分析
    • mRNAテクノロジーに対する学術的および産業界の関心の高まり
    • mRNAワクチンの利点
    • mRNA調査のための資金を増やす
  • 市場抑制要因分析
    • mRNAベースの製品承認に関する有効な政府規制が存在しない
    • mRNA合成材料の高コスト
  • 市場課題分析
    • 長期的で手頃な価格の製造プロセスの欠如
• 普及と成長見通しのマッピング
• mRNA合成材料市場- ポーターの分析
• mRNA合成材料市場SWOT分析
• Covid-19影響分析

第4章 タイプビジネス分析

• mRNA合成材料市場-型変動分析
• キャッピング剤
• ヌクレオチド
• プラスミドDNA
• その他

第5章 アプリケーションのビジネス分析

• mRNA合成材料市場-アプリケーションの変動分析
• 治療薬の製造
• ワクチンの生産
• その他

第6章 エンドユーザーのビジネス分析

• mRNA合成材料市場-エンドユーザーの変動分析
• バイオ医薬品および製薬会社
• クロ＆コモ
• 学術調査機関

第7章 地域のビジネス分析

• mRNA合成材料市場：地域変動分析
• 北米
  • SWOT分析
  • 米国
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • カナダ
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
• 欧州
  • SWOT分析
  • ドイツ
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • 英国
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • フランス
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • イタリア
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • スペイン
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • デンマーク
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • スウェーデン
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • ノルウェー
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
• アジア太平洋地域
  • SWOT分析
    • アジア太平洋地域のmRNA合成原材料、2018年から2030年（百万米ドル）
  • 日本
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
    • 日本のmRNA合成材料市場、2018年～2030年（百万米ドル）
  • 中国
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
    • 中国のmRNA合成材料市場、2018年～2030年（百万米ドル）
  • インド
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
    • インドのmRNA合成材料市場、2018年から2030年（百万米ドル）
  • オーストラリア
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
    • オーストラリアのmRNA合成材料市場、2018年から2030年（百万米ドル）
  • 韓国
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
    • 韓国のmRNA合成材料市場、2018年～2030年（百万米ドル）
  • タイ
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
    • タイのmRNA合成材料市場、2018年～2030年（USD Million）
• ラテンアメリカ
  • SWOT分析
    • ラテンアメリカのmRNA合成材料市場、2018年から2030年（百万米ドル）
  • ブラジル
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
    • ブラジルのmRNA合成材料市場、2018年から2030年（百万米ドル）
  • メキシコ
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
    • メキシコのmRNA合成材料市場、2018年～2030年（百万米ドル）
  • アルゼンチン
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
    • アルゼンチンのmRNA合成材料市場、2018年～2030年（USD Million）
• 中東とアフリカ
  • SWOT分析
  • 南アフリカ
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • サウジアラビア
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • アラブ首長国連邦
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み
  • クウェート
    • 主要な国のダイナミクス
    • 競合シナリオ
    • 規制の枠組み

第8章 競合情勢

• 参入企業の分類
  • F. Hoffmann - La Roche Ltd.
  • Jena Bioscience Gmbh
  • Merck KGaA
  • Yeasen Biotechnology (Shanghai) Co.,Ltd.
  • BOC Sciences
  • Thermo Fisher Scientific, Inc.
  • Maravai Lifesciences
  • New England Biolabs
  • Creative Biogene
  • Hongene
• 財務実績
• 参入企業の分類
  • 市場のリーダー
    • mRNA合成原材料市場シェア分析、2022年
  • 戦略マッピング
    • 拡張
    • 取得
    • コラボレーション
    • 製品・サービスのローンチ
    • パートナーシップ
    • その他

List of Tables

• Table 1 List of secondary sources
• Table 2 List of abbreviations
• Table 3 Global mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 4 Global mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 5 Global mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 6 Global mRNA synthesis raw materials market, by region, 2018 - 2030 (USD Million)
• Table 7 North America mRNA synthesis raw materials market, by country, 2018 - 2030 (USD Million)
• Table 8 North America mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 9 North America mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 10 North America mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 11 U.S. mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 12 U.S. mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 13 U.S. mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 14 Canada mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 15 Canada mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 16 Canada mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 17 Europe mRNA synthesis raw materials market, by country, 2018 - 2030 (USD Million)
• Table 18 Europe mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 19 Europe mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 20 Europe mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 21 Germany mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 22 Germany mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 23 Germany mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 24 U.K. mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 25 U.K. mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 26 U.K. mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 27 France mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 28 France mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 29 France mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 30 Italy mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 31 Italy mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 32 Italy mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 33 Spain mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 34 Spain mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 35 Spain mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 36 Denmark mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 37 Denmark mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 38 Denmark mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 39 Sweden mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 40 Sweden mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 41 Sweden mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 42 Norway mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 43 Norway mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 44 Norway mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 45 Asia Pacific mRNA synthesis raw materials market, by country, 2018 - 2030 (USD Million)
• Table 46 Asia Pacific mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 47 Asia Pacific mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 48 Asia Pacific mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 49 Japan mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 50 Japan mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 51 Japan mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 52 China mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 53 China mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 54 China mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 55 India mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 56 India mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 57 India mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 58 South Korea mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 59 South Korea mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 60 South Korea mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 61 Australia mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 62 Australia mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 63 Australia mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 64 Thailand mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 65 Thailand mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 66 Thailand mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 67 Latin America mRNA synthesis raw materials market, by country, 2018 - 2030 (USD Million)
• Table 68 Latin America mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 69 Latin America mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 70 Latin America mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 71 Brazil mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 72 Brazil mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 73 Brazil mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 74 Mexico mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 75 Mexico mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 76 Mexico mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 77 Argentina mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 78 Argentina mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 79 Argentina mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 80 Middle East & Africa mRNA synthesis raw materials market, by country, 2018 - 2030 (USD Million)
• Table 81 Middle East & Africa mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 82 Middle East & Africa mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 83 Middle East & Africa mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 84 South Africa mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 85 South Africa mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 86 South Africa mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 87 Saudi Arabia mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 88 Saudi Arabia mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 89 Saudi Arabia mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 90 UAE mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 91 UAE mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 92 UAE mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 93 Kuwait mRNA synthesis raw materials market, by type, 2018 - 2030 (USD Million)
• Table 94 Kuwait mRNA synthesis raw materials market, by application, 2018 - 2030 (USD Million)
• Table 95 Kuwait mRNA synthesis raw materials market, by end-user, 2018 - 2030 (USD Million)
• Table 96 Participant's overview
• Table 97 Financial performance
• Table 98 Key companies undergoing expansions
• Table 99 Key companies undergoing acquisitions
• Table 100 Key companies undergoing collaborations
• Table 101 Key companies launching new products/services
• Table 102 Key companies undergoing partnerships
• Table 103 Key companies undertaking other strategies

List of Figures

• Fig. 1 Market research process
• Fig. 2 Data triangulation techniques
• Fig. 3 Primary research pattern
• Fig. 4 Market research approaches
• Fig. 5 Value-chain-based sizing & forecasting
• Fig. 6 QFD modeling for market share assessment
• Fig. 7 Market formulation & validation
• Fig. 8 Market summary, 2022 (USD Million)
• Fig. 9 Market segmentation & scope
• Fig. 10 Market driver impact
• Fig. 11 Market restraint impact
• Fig. 12 Penetration & growth prospect mapping
• Fig. 13 Porter's analysis
• Fig. 14 SWOT analysis
• Fig. 15 mRNA synthesis raw materials market: Product outlook and key takeaways
• Fig. 16 mRNA synthesis raw materials market: Product movement analysis
• Fig. 17 Global capping agents market, 2018 - 2030 (USD Million)
• Fig. 18 Global nucleotides market, 2018 - 2030 (USD Million)
• Fig. 19 Global plasmid DNA market, 2018 - 2030 (USD Million)
• Fig. 20 Global other mRNA synthesis raw materials, by type market, 2018 - 2030 (USD Million)
• Fig. 21 mRNA synthesis raw materials market: Application outlook and key takeaways
• Fig. 22 mRNA synthesis raw materials market: Application movement analysis
• Fig. 23 Global therapeutics production market, 2018 - 2030 (USD Million)
• Fig. 24 Global vaccine production market, 2018 - 2030 (USD Million)
• Fig. 25 Global other applications market, 2018 - 2030 (USD Million)
• Fig. 26 mRNA synthesis raw materials market: End-use outlook and key takeaways
• Fig. 27 mRNA synthesis raw materials market: End-use movement analysis
• Fig. 28 Global biopharmaceutical & pharmaceutical companies market, 2018 - 2030 (USD Million)
• Fig. 29 Global CROs & CMOs market, 2018 - 2030 (USD Million)
• Fig. 30 Global academic & research institutions market, 2018 - 2030 (USD Million)
• Fig. 31 mRNA synthesis raw materials market: Regional outlook and key takeaways
• Fig. 32 North America: SWOT Analysis
• Fig. 33 North America mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
• Fig. 34 U.S. key country dynamics
• Fig. 35 U.S. mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
• Fig. 36 Canada key country dynamics
• Fig. 37 Canada mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
• Fig. 38 Europe: SWOT Analysis
• Fig. 39 Europe mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 40 Germany key country dynamics
• Fig. 41 Germany mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 42 France key country dynamics
• Fig. 43 France mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 44 U.K. key country dynamics
• Fig. 45 U.K. mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 46 Italy key country dynamics
• Fig. 47 Italy mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 48 Spain key country dynamics
• Fig. 49 Spain mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 50 Denmark key country dynamics
• Fig. 51 Denmark mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 52 Sweden key country dynamics
• Fig. 53 Sweden mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 54 Norway key country dynamics
• Fig. 55 Norway mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 56 Asia Pacific: SWOT Analysis
• Fig. 57 Asia Pacific mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 58 China key country dynamics
• Fig. 59 China mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 60 India key country dynamics
• Fig. 61 India mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 62 South Korea key country dynamics
• Fig. 63 South Korea mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 64 Japan key country dynamics
• Fig. 65 Japan mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 66 Australia key country dynamics
• Fig. 67 Australia mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 68 Thailand key country dynamics
• Fig. 69 Thailand mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 70 Latin America: SWOT Analysis
• Fig. 71 Latin America mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 72 Brazil key country dynamics
• Fig. 73 Brazil mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 74 Mexico key country dynamics
• Fig. 75 Mexico mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 76 Argentina key country dynamics
• Fig. 77 Argentina mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 78 MEA: SWOT Analysis
• Fig. 79 MEA mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 80 South Africa key country dynamics
• Fig. 81 South Africa mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 82 Saudi Arabia key country dynamics
• Fig. 83 Saudi Arabia mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 84 UAE key country dynamics
• Fig. 85 UAE mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 86 Kuwait key country dynamics
• Fig. 87 Kuwait mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
• Fig. 88 Market participant categorization
• Fig. 89 mRNA synthesis raw materials market share analysis, 2022
• Fig. 90 Strategy framework

mRNA Synthesis Raw Materials Market Growth & Trends:

The global mRNA synthesis raw materials market size is projected to reach USD 3.3 billion by 2030, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 2.1% from 2023 to 2030. The major factors driving the market growth include growing academic and industrial interest in mRNA technology, the advantages of mRNA vaccines, and increasing funding for research. In addition, the increasing therapeutic applications of RNA technology are projected to offer lucrative opportunities for the mRNA synthesis raw materials market during the forecast period.

The COVID-19 pandemic has increased the demand for mRNA synthesis raw materials for developing an efficient vaccine to battle infectious diseases. mRNA vaccines are a safe and efficient method for preventing COVID-19. In addition, the advantages associated with the mRNA COVID-19 vaccines have sparked the attention of pharmaceutical businesses in delivering vaccines swiftly across the globe. For instance, the National Institute of Allergy and Infectious Diseases and Moderna, Inc. mutually developed the mRNA-1273 (NIAID) in March 2020. As a result, the usage of mRNA vaccines increased significantly during the COVID-19 pandemic.

Furthermore, many major pharmaceutical firms have started working on mRNA-based therapeutics, including Novartis, Alexion, AstraZeneca, Pfizer, Sanofi Pasteur, and Shire. For instance, in January 2022, according to a development and option agreement between Pfizer Inc. and Acuitas Therapeutics, Pfizer will have the option to license Acuitas' LNP technology for up to 10 targets for the development of mRNA therapeutics & vaccines. Therefore, the adoption rate of mRNA synthesis raw materials has increased among pharma & biotech companies, which further fuels the market growth.

Moreover, due to the temporary nature of mRNA translation and lack of integration of the foreign material into the cell's genome, the resulting cellular therapeutic product has a number of benefits over the one obtained by a more conventional approach. Some of the advantages include easier production under acceptable manufacturing procedures, reduced cytotoxicity from on-target off-tumor effects, and better clinical validation and regulatory treatment. Thus, such advantages are expected to increase the demand for mRNA therapeutics and further boost market growth.

Additionally, regarding the treatment and prevention of several diseases, mRNA-based technologies have been proven to be incredibly promising. Tremendous advances in technology and scientific study over the past ten years have made mRNA a feasible therapeutic option, eliminating some of the problems with its use, such as its brief half-life and innate immunogenicity. For instance, as mRNA technology advances, its fusion with new adoptive immunotherapies may result in safer and more efficient methods, such as the creation of cutting-edge chimeric antigen receptor T-cells. Therefore, advancements in mRNA technology are projected to open new avenues for market growth.

However, the high cost of raw materials may impede the market during the study period. For instance, the purchase price of raw materials, such as CleanCap AG, accounts for around 45% of the total raw material costs incurred while producing both vaccines. In addition, the regulatory framework pertaining to approval processes has always been the most critical restraining factor in the biotechnology, pharmaceutical, and medical technology industry. The absence of effective regulatory framework/guidelines for the therapeutic sector in developing countries such as China and India, where the mRNA synthesis raw materials market holds great growth potential due to the presence of a large patient base, is anticipated to impede the market growth in the coming years.

mRNA Synthesis Raw Materials Market Report Highlights:

• The capping agents segment held the largest share of 40.6% in 2022 owing to the advancements in the capping technology and their applications in the biopharma industry and research

• By application, the vaccine production segment captured the highest share of 85.30% in 2022. This can be attributed to the rapid production of mRNA vaccines compared to the conventional vaccines that use cell-culture-based production routes, which are often prone to failure

• North America held the highest revenue share of 35.5% in 2022, due to the presence of key players, the availability of an established commercial infrastructure for biotechnology and pharmaceutical companies, and high research and development investments in the region

• By end-user, the biopharmaceutical and pharmaceutical companies segment dominated the market in 2022 due to the increasing investments in the biopharmaceutical sector and the rising pipeline, which has boosted the need for mRNA synthesis raw materials

Table of Contents

Chapter 1 Methodology and Scope

• 1.1 Research Methodology
• 1.2 Research Assumptions
  • 1.2.1 Estimates And Forecast Timeline
• 1.3 Information Procurement
  • 1.3.1 Purchased Database
  • 1.3.2 Gvr's Internal Database
  • 1.3.3 Secondary Sources
  • 1.3.4 Primary Research
• 1.4 Information Or Data Analysis
  • 1.4.1 Data Analysis Models
• 1.5 Market Formulation & Validation

Chapter 2 Executive Summary

• 2.1 Market Snapshot
• 2.2 Segment Snapshot
• 2.3 Competitive Landscape Snapshot

Chapter 3 Market Variables, Trends, & Scope

• 3.1 Parent Market Analysis
• 3.2 Market Dynamics
  • 3.2.1 Market Driver Analysis
    • 3.2.1.1 Growing Academic And Industrial Interest In mRNA Technology
    • 3.2.1.2 Advantages Of mRNA Vaccines
    • 3.2.1.3 Increasing Funding For mRNA Research
  • 3.2.2 Market Restraint Analysis
    • 3.2.2.1 Nonexistence Of Effective Government Regulations For mRNA - Based Product Approvals
    • 3.2.2.2 High Cost Of mRNA Synthesis Raw Materials
  • 3.2.3 Market Challange Analysis
    • 3.2.3.1 Lack Of Long - Lasting And Affordable Manufacturing Processes
• 3.3 Penetration &Growth Prospect Mapping
• 3.4 mRNA Synthesis Raw Materials Market - Porter's Analysis
• 3.5 mRNA Synthesis Raw Materials Market - Swot Analysis
• 3.6 Covid - 19 Impact Analysis

Chapter 4 Type Business Analysis

• 4.1 mRNA Synthesis Raw Materials Market - Type Movement Analysis
• 4.2 Capping Agents
  • 4.2.1 Global Capping Agents Market, 2018 - 2030 (USD Million)
• 4.3 Nucleotides
  • 4.3.1 Global Nucleotides Market, 2018 - 2030 (USD Million)
• 4.4 Plasmid Dna
  • 4.4.1 Global Plasmid Dna Market, 2018 - 2030 (USD Million)
• 4.5 Others
  • 4.5.1 Global Other Types Market, 2018 - 2030 (USD Million)

Chapter 5 Application Business Analysis

• 5.1 mRNA Synthesis Raw Materials Market - Application Movement Analysis
• 5.2 Therapeutics Production
  • 5.2.1 Global Therapeutics Production Market, 2018 - 2030 (USD Million)
• 5.3 Vaccine Production
  • 5.3.1 Global Vaccine Production Market, 2018 - 2030 (USD Million)
• 5.4 Others
  • 5.4.1 Global Other Applications Market, 2018 - 2030 (USD Million)

Chapter 6 End - User Business Analysis

• 6.1 mRNA Synthesis Raw Materials Market - End User Movement Analysis
• 6.2 Biopharmaceutical & Pharmaceutical Companies
  • 6.2.1 Global Biopharmaceutical & Pharmaceutical Companies, 2018 - 2030 (USD Million)
• 6.3 Cros & Cmos
  • 6.3.1 Global Cros & Cmos, 2018 - 2030 (USD Million)
• 6.4 Academic And Research Institutions
  • 6.4.1 Global Academic And Research Institutions, 2018 - 2030 (USD Million)

Chapter 7 Regional Business Analysis

• 7.1 mRNA Synthesis Raw Materials Market: Regional Movement Analysis
• 7.2 North America
  • 7.2.1 Swot Analysis
    • 7.2.1.1 North America mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.2.2 U.S.
    • 7.2.2.1 Key Country Dynamics
    • 7.2.2.2 Competitive Scenario
    • 7.2.2.3 Regulatory Framework
    • 7.2.2.4 U.S. mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.2.3 Canada
    • 7.2.3.1 Key country dynamics
    • 7.2.3.2 Competitive scenario
    • 7.2.3.3 Regulatory framework
    • 7.2.3.4 Canada mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
• 7.3 Europe
  • 7.3.1 Swot Analysis
    • 7.3.1.1 Europe mRNA Synthesis Raw Materials Market Estimates And Forecast, 2018 - 2030 (USD Million)
  • 7.3.2 Germany
    • 7.3.2.1 Key Country Dynamics
    • 7.3.2.2 Competitive Scenario
    • 7.3.2.3 Regulatory Framework
    • 7.3.2.4 Germany mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.3.3 U.K.
    • 7.3.3.1 Key Country Dynamics
    • 7.3.3.2 Competitive Scenario
    • 7.3.3.3 Regulatory Framework
    • 7.3.3.4 Uk mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.3.4 France
    • 7.3.4.1 Key Country Dynamics
    • 7.3.4.2 Competitive Scenario
    • 7.3.4.3 Regulatory Framework
    • 7.3.4.4 France mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.3.5 Italy
    • 7.3.5.1 Key Country Dynamics
    • 7.3.5.2 Competitive Scenario
    • 7.3.5.3 Regulatory Framework
    • 7.3.5.5 Italy mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.3.6 Spain
    • 7.3.6.1 Key Country Dynamics
    • 7.3.6.2 Competitive Scenario
    • 7.3.6.3 Regulatory Framework
    • 7.3.6.4 Spain mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.3.7 Denmark
    • 7.3.7.1 Key Country Dynamics
    • 7.3.7.2 Competitive Scenario
    • 7.3.7.3 Regulatory Framework
    • 7.3.7.4 Denmark mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.3.8 Sweden
    • 7.3.8.1 Key Country Dynamics
    • 7.3.8.2 Competitive Scenario
    • 7.3.8.3 Regulatory Framework
    • 7.3.8.4 Sweden mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.3.9 Norway
    • 7.3.9.1 Key country dynamics
    • 7.3.9.2 Competitive scenario
    • 7.3.9.3 Regulatory framework
    • 7.3.9.4 Norway mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
• 7.4 Asia Pacific
  • 7.4.1 Swot Analysis
    • 7.4.1.1 Asia Pacific mRNA Synthesis Raw Materials, 2018 - 2030 (USD Million)
  • 7.4.2 Japan
    • 7.4.2.1 Key Country Dynamics
    • 7.4.2.2 Competitive Scenario
    • 7.4.2.3 Regulatory Framework
    • 7.4.2.4 Japan mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.4.3 China
    • 7.4.3.1 Key Country Dynamics
    • 7.4.3.2 Competitive Scenario
    • 7.4.3.3 Regulatory Framework
    • 7.4.3.4 China mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.4.4 India
    • 7.4.4.1 Key Country Dynamics
    • 7.4.4.2 Competitive Scenario
    • 7.4.4.3 Regulatory Framework
    • 7.4.4.4 India mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.4.5 Australia
    • 7.4.5.1 Key Country Dynamics
    • 7.4.5.2 Competitive Scenario
    • 7.4.5.3 Regulatory Framework
    • 7.4.5.4 Australia mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.4.6 South Korea
    • 7.4.6.1 Key Country Dynamics
    • 7.4.6.2 Competitive Scenario
    • 7.4.6.3 Regulatory Framework
    • 7.4.6.4 South Korea mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.4.7 Thailand
    • 7.4.7.1 Key country dynamics
    • 7.4.7.2 Competitive scenario
    • 7.4.7.3 Regulatory framework
    • 7.4.7.4 Thailand mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
• 7.5 Latin America
  • 7.5.1 Swot Analysis
    • 7.5.1.1 Latin America mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.5.2 Brazil
    • 7.5.2.1 Key Country Dynamics
    • 7.5.2.2 Competitive Scenario
    • 7.5.2.3 Regulatory Framework
    • 7.5.2.4 Brazil mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.5.3 Mexico
    • 7.5.3.1 Key Country Dynamics
    • 7.5.3.2 Competitive Scenario
    • 7.5.3.3 Regulatory Framework
    • 7.5.3.4 Mexico mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
  • 7.5.4 Argentina
    • 7.5.4.1 Key country dynamics
    • 7.5.4.2 Competitive scenario
    • 7.5.4.3 Regulatory framework
    • 7.5.4.4 Argentina mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
• 7.6 Middle East & Africa
  • 7.6.1 Swot Analysis
    • 7.6.1.1 Mea mRNA Synthesis Raw Materials Market Estimates And Forecast, 2018 - 2030 (USD Million)
  • 7.6.2 South Africa
    • 7.6.2.1 Key country dynamics
    • 7.6.2.2 Competitive scenario
    • 7.6.2.3 Regulatory framework
    • 7.6.2.4 South Africa mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
  • 7.6.3 Saudi Arabia
    • 7.6.3.1 Key country dynamics
    • 7.6.3.2 Competitive scenario
    • 7.6.3.3 Regulatory framework
    • 7.6.3.4 Saudi Arabia mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
  • 7.6.4 UAE
    • 7.6.4.1 Key country dynamics
    • 7.6.4.2 Competitive scenario
    • 7.6.4.3 Regulatory framework
    • 7.6.4.4 UAE mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
  • 7.6.5 KUWAIT
    • 7.6.5.1 Key country dynamics
    • 7.6.5.2 Competitive scenario
    • 7.6.5.3 Regulatory framework
    • 7.6.5.4 Kuwait mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)

Chapter 8 Competitive Landscape

• 8.1 Participant's Overview
  • 8.1.1 F. Hoffmann - La Roche Ltd.
  • 8.1.2 Jena Bioscience Gmbh
  • 8.1.3 Merck KGaA
  • 8.1.4 Yeasen Biotechnology (Shanghai) Co.,Ltd.
  • 8.1.5 BOC Sciences
  • 8.1.6 Thermo Fisher Scientific, Inc.
  • 8.1.7 Maravai Lifesciences
  • 8.1.8 New England Biolabs
  • 8.1.9 Creative Biogene
  • 8.1.10 Hongene
• 8.2 Financial Performance
• 8.3 Participant Categorization
  • 8.3.1 Market Leaders
    • 8.3.1.1 mRNA Synthesis Raw Materials Market Share Analysis, 2022
  • 8.3.2 Strategy Mapping
    • 8.3.2.1 Expansion
    • 8.3.2.2 Acquisition
    • 8.3.2.3 Collaborations
    • 8.3.2.4 Product/service launch
    • 8.3.2.5 Partnerships
    • 8.3.2.6 Others