タンパク質標識の世界市場-2023-2030

市場概要

タンパク質標識の世界市場規模は、予測期間（2023-2030年）にCAGR6.4％で成長するとされています。

生物学的研究では、標識されたタンパク質とその結合パートナーの精製または検出を容易にするために、目的のタンパク質に共有結合される分子標識を使用する必要があります。タンパク質標識の主な目的は、生物学的プロセスのモニタリング、化合物の信頼性の高い定量化、多重化サンプル中のタンパク質修飾やアイソフォームの特異的検出、検出感度の向上、検出ワークフローの簡素化です。

市場力学

世界のタンパク質標識市場を牽引する主な要因は、世界の慢性疾患の増加、研究開発費の上昇、生物工学技術の採用です。新規製品の発売の増加が、タンパク質標識市場の成長に寄与しています。

ゲノム解読やプロテオミクス研究の高まり、高度なバイオエンジニアリング技術の採用が、市場の成長を促進すると予想されます。

生物学的機能および正常な細胞機能の調査における翻訳後修飾研究のためのこれらのタンパク質標識製品の採用の増加、さまざまな技術における高度なバイオエンジニアリング技術の採用の増加、がんなどの慢性疾患の有病率の増加と診断の必要性が、タンパク質標識市場を牽引しています。また、世界の慢性疾患の増加も市場の成長を後押ししています。また、多くのヘルスケア企業が新製品を開発するために研究開発活動を活発化させています。

ウェスタンブロッティング、ELISA、免疫組織化学、免疫細胞化学、フローサイトメトリーなどの検査では、さまざまな医学・臨床研究用のタンパク質標識法が必要とされています。市場では複数の用途に応じた複数のラベルが入手可能であり、用途に応じて使用する名称の種類や標識戦略を慎重に選択する必要があります。ゲノム解読やプロテオミクス研究の需要の急増が、市場の成長を後押ししています。さらに、新規ワクチンの研究開発の増加や、主要企業による技術的に高度な製品の提供も、市場の成長に重要な役割を果たすと予想されます。

さまざまな新規製品の発売、規制当局の承認、調査研究は、市場の成長に寄与しています。例えば、2021年9月17日、パーキンエルマー社は、ライフサイエンス試薬・抗体プロバイダーのBioLegend社の買収を総額約52億5000万米ドルで完了したことを発表しました。この買収により、パーキンエルマーのライフサイエンス・フランチャイズは、プロテオゲノミクス、サイトメトリー、マルチプレックス・アッセイ、磁気細胞分離、組み換えタンパク質、バイオプロセシングなどの高成長分野へと拡大されました。

熟練した専門家が限られていることが、市場の成長を妨げると予想されます。

しかし、現在のシナリオでは熟練した専門家の利用可能性が限られていること、先進的な製品を発売するための主要企業間の競争の激化、製品の用途が限定されていることが、市場の成長を阻害する可能性があります。

また、タンパク質標識のコストが高いことも、成長抑制の主な要因です。化学標識には、修飾されたタンパク質が1つ以上の活性を失うという欠点があります。そのため、ラベル付けされたタンパク質の活性は、ラベル付けされていないタンパク質と比較して試験する必要があります。また、代謝標識では、放射性タンパク質の精製が必要であり、低温装置や遠心分離機の長期間の使用により、放射能を構成することが困難です。

COVID-19の影響分析

パンデミックは、世界の財務的な期待、オペレーション、危機対応戦略にマイナスの影響を与えました。COVID-19の発生はヘルスケア産業に深刻な影響を及ぼしています。COVID患者の増加により様々な研究および臨床試験が延期されたため、タンパク質標識市場はCOVIDによる莫大な損失を経験しました。様々な取り組み、製品の発売、技術革新、コラボレーション、合併が世界中で起こっており、市場の成長を後押ししています。例えば、2021年7月28日、Promega Corporationは、米国FDAがPromega OncoMate MSI Dx Analysis Systemを認可したと発表しました。米国の病理医や腫瘍医は、大腸がん患者のリンチ症候群のスクリーニングにマイクロサテライト不安定性（MSI）診断を活用することができます。

目次

第1章 調査手法と調査範囲

• 調査手法
• 調査目的および調査範囲

第2章 市場の定義と概要

第3章 エグゼクティブサマリー

第4章 市場力学

• 市場影響要因
  • 促進要因
    • ゲノム解読とプロテオミクス研究の高まり
    • 高度なバイオエンジニアリング技術の採用の増加
  • 抑制要因
    • 熟練した専門家の不足
  • ビジネスチャンス
  • 影響分析

第5章 産業分析

• ポーターのファイブフォース分析
• サプライチェーン分析
• プライシング分析

第6章 COVID-19の分析

• COVID-19の市場分析
  • COVID-19以前の市場シナリオ
  • COVID-19の現在の市場シナリオ
  • COVID-19の後、または将来のシナリオ
• COVID-19の中での価格ダイナミクス
• 需要-供給スペクトラム
• パンデミック時の市場に関連する政府の取り組み
• メーカーの戦略的取り組み
• まとめ

第7章 製品タイプ別

• キット
• 試薬
  • プローブ・タグ
  • 酵素
  • ビオチン
  • その他
• サービス

第8章 標識タイプ別

• In-Vitro標識
• In-Vivo標識
• バイオオルトゴナル標識

第9章 アプリケーション別

• セルベースアッセイ
• 免疫学的手法
• プロテインマイクロアレイ
• マススペクトロスコピー
• 蛍光顕微鏡

第10章 エンドユーザー別

• 病院
• 研究機関
• 診断センター
• その他

第11章 地域別

• 北米
  • 米国
  • カナダ
  • メキシコ
• 欧州
  • ドイツ
  • 英国
  • フランス
  • イタリア
  • スペイン
  • その他欧州
• 南米
  • ブラジル
  • アルゼンチン
  • その他の南米地域
• アジア太平洋地域
  • 中国
  • インド
  • 日本
  • オーストラリア
  • その他アジア太平洋地域
• 中東・アフリカ地域

第12章 競合情勢

• 主な展開と戦略
• 企業シェア分析
• 製品ベンチマーク
• 注目の主要企業リスト

第13章 企業プロファイル

• Thermo Fisher Scientific
  • 企業概要
  • 製品ポートフォリオと説明
  • 主なハイライト
  • 財務概要
• Merck KGaA
• PerkinElmer Inc.
• GE Healthcare
• Qiagen N.V.
• New England Biolabs
• SeraCare Life Sciences Inc.
• Promega Corporation
• Bio-Rad Laboratories, Inc.
• Agilent Technologies

第14章 タンパク質標識の世界市場-DataM

Market Overview

The global protein labeling market size was valued at US$ XX mill-ion in 2023 and is estimated to reach US$ XX million by 2030, growing at a CAGR of 6.4% during the forecast period (2023-2030).

Biological research requires the use of molecular labels that are covalently attached to a protein of interest to facilitate the purification or detection of the labeled protein and its binding partners. The primary purpose of protein labeling is monitoring the biological process, reliable quantification of compounds, specific detection of protein modifications and isoforms in multiplexed samples, enhancement of detection sensitivity, and simplification of detection workflows.

Market Dynamics

The major factors driving the global protein labeling market are an increase in the number of chronic diseases globally, rising research and development expenditure and the adoption of bioengineering techniques. An increase in novel product launches contributes to the growth of the protein labeling market.

The rising genome sequencing and proteomics research and adoption of sophisticated bioengineering techniques are expected to drive the market's growth.

The rising adoption of these protein labeling products for post-translational modification studies in the investigation of biological functions as well as normal cell functioning, the rising adoption of sophisticated bioengineering techniques in various technologies, and the growth in the prevalence of chronic diseases such as cancer and the need for diagnosis drive the protein labeling market. An increase in chronic diseases globally is also aiding market growth. There has been an increase in R&D activities by many healthcare companies to develop novel products.

Test that includes western blotting, ELISA, immunohistochemistry, immunocytochemistry, and flow cytometry requires protein labeling methods for various medical and clinical studies. There is an availability of multiple labels in the market for multiple applications, and the type of name and labeling strategy used must be carefully selected for each application. The surge in demand for genome sequencing and proteomics research is fueling the market's growth. Moreover, the increase in research and development of novel vaccines and the availability of technologically advanced products by key players are also expected to play a vital role in the market's growth.

Various novel product launches, regulatory approvals and research studies contribute to the market's growth. For instance, in September 17, 2021, PerkinElmer, Inc. announced its completion of the acquisition of BioLegend, a life science reagents and antibodies provider, for approximately $5.25 billion in total consideration. This acquisition expands the life science franchise of PerkinElmer into high-growth areas like proteogenomics, cytometry, multiplex assays, magnetic cell separation, recombinant proteins and bioprocessing.

The skillful professional's limited availability is expected to hamper the market's growth.

However, the limited availability of skillful professionals in the current scenario, increased competition among key players for launching advanced products, and limited product applications may hinder the growth of the market.

The high cost of protein labeling is also a leading factor for restrained growth, as chemical labeling has a drawback that the protein that has been modified can lose one or more activities. So, the labeled protein's activity should be tested relative to unlabeled protein. Metabolic labeling also needs purification of the radioactive protein, and over the extended use of cold room equipment and centrifuges, it is difficult to consist the radioactivity.

COVID-19 Impact Analysis

The pandemic has negatively impacted global financial expectations, operations and crisis response strategy. The COVID-19 outbreak has severely impacted the healthcare industry. The protein labeling market has experienced huge losses due to COVID, as various research and clinical trials got postponed due to the increasing number of COVID cases. Various initiatives, product launches, innovations, collaborations and mergers are happening worldwide, boosting the market's growth. For instance, in July 28, 2021, Promega Corporation announced that U.S. FDA had cleared its Promega OncoMate MSI Dx Analysis System. Pathologists and oncologists in the US can utilize microsatellite instability (MSI) diagnostic for screening Lynch syndrome in colorectal cancer patients.

Segment Analysis

The reagent segment is expected to grow at the fastest CAGR during the forecast period (2022-2029)

The reagent segment is the highest market holder in the global protein labeling market. The global protein labeling market is segmented based on product type as kits, reagents and services. The reagents segment is the largest market shareholder due to its high demand and usage, increasing prevalence of cancer and rising adoption of these for protein labeling products. Reagents are further sub-segmented into probes, biotin, proteins, enzymes and others. These reagents hold the largest market share due to increased demand for peptide-binding agents and increased research and development activities, which are expected to remain high during the forecast period.

The protein labeling reagents are developed to label target proteins selectively. These products are classic dyes, biotinylation reagents, radioisotope labels, fluorescent labels, assays, molecular probes, and labeling kits. Fluorophores, stable isotopes, and mass tags are three important tags implemented during protein labeling. Western blotting, immunohistochemistry, ELISA, immunocytochemistry, and flow cytometry require protein labeling methods for various medical and clinical studies. There is an availability of multiple labels in the market for multiple applications, and the type of name and labeling strategy used must be carefully selected for each application.

The growing number of regulatory approvals, technological advancements, product launches, and research/clinical trial studies drive the market's growth. For instance, in July 28, 2021, PerkinElmer, Inc announced the launch of its four-novel ready-to-use AlphaLISA KRAS kits, developed to provide scientists with a better understanding of complex KRAS protein structures as well as mutations so that potential new therapeutic candidates identification gets more easy, precise and quick for a broad range of prevalent cancers.

Geographical Analysis

North America holds the largest market share in the global protein labeling market.

North America dominates the global protein labeling market, primarily due to its large population, excellent medical infrastructure, and rising number of chronic diseases like cancer. The market is expected to grow at a relatively high pace during the forecast period due to healthcare expenditure in the US. The market's significant size is attributed to the high medical expenditure.

Increasing expenditure on healthcare and raising awareness among people is also contributing to the market's growth in this region. Advancement of products for various applications, including cell-based assay, immunological techniques, mass spectroscopy, protein microarrays, fluorescence microscopy, increase in pharmaceutical establishment across the region, government approvals, and key players in the region are contributing to the growth of the protein labeling market.

Moreover, the growing number of product launches is responsible for the market's growth. Many key developments, regulatory approvals, technological advancements, collaborations, and agreements are taking place in this region. For instance, in January 11, 2022, Merck, a science and technology company, announced its Stable Isotope Center of Excellence expansion in Miamisburg, Ohio. The expansion strengthens the continued commitment of the company to this product category, which shows growing utility in industrial, diagnostic and research applications.

Competitive Landscape

The protein labeling market is moderately competitive with local and global companies' presence. Thermo Fisher Scientific, Merck KGaA, PerkinElmer Inc., GE Healthcare, Qiagen N.V., New England Biolabs, SeraCare Life Sciences Inc., Promega Corporation, Bio-Rad Laboratories, Inc., Agilent Technologies and more. The key players are adopting various growth strategies such as product launches, mergers & acquisitions, partnerships, and collaborations, contributing to the market's growth. For instance, in June 7, 2021, Thermo Fisher Scientific announced its agreement with Advanced Electrophoresis Solutions Ltd (AES), protein imaging technologies specialists, to combine mass spectrometry (MS) with essential protein separation techniques for the advancement of therapeutic protein development via streamlined characterization.

Thermo Fisher Scientific.

Overview: This is a company that supplies a variety of scientific or analytical instruments, lab reagents & consumables, and some scientific software services. It was founded in 1956 and headquartered in Waltham, Massachusetts, U.S.

Product Portfolio:

Fluorescent Protein Labeling Kits: The fluorescent dye attachment to proteins or other biomolecules is a general strategy used to better understand protein function and structure. These fluorescent proteins can be utilized in various applications, like immunochemistry, receptor labeling, cell tracing and fluorescence spectroscopy.

Key Developments: In October 31, 2022, Thermo Fisher Scientific Inc. announced entering into a definitive acquisition agreement with The Binding Site Group, a specialty diagnostics company that provides specialized diagnostic instruments and assays, from a group of shareholders led by Nordic Capital, a European private equity firm.

The global protein labeling market report would provide access to approx.: 45+ market data tables, 40+ figures and 200 (approximate) pages.

Table of Contents

1. Methodology and Scope

• 1.1. Research Methodology
• 1.2. Research Objective and Scope of the Report

2. Market Definition and Overview

3. Executive Summary

4. Market Dynamics

• 4.1. Market Impacting Factors
  • 4.1.1. Drivers
    • 4.1.1.1. Rising genome sequencing and proteomics research
    • 4.1.1.2. Increasing adoption of sophisticated bioengineering techniques
  • 4.1.2. Restraints:
    • 4.1.2.1. Limited availability of skillful professionals
  • 4.1.3. Opportunity
  • 4.1.4. Impact Analysis

5. Industry Analysis

• 5.1 Porter's Five Forces Analysis
• 5.2 Supply Chain Analysis
• 5.3 Pricing Analysis

6. COVID-19 Analysis

• 6.1. Analysis of Covid-19 on the Market
  • 6.1.1. Before COVID-19 Market Scenario
  • 6.1.2. Present COVID-19 Market Scenario
  • 6.1.3. After COVID-19 or Future Scenario
• 6.2. Pricing Dynamics Amid Covid-19
• 6.3. Demand-Supply Spectrum
• 6.4. Government Initiatives Related to the Market During the Pandemic
• 6.5. Manufacturer's Strategic Initiatives
• 6.6. Conclusion

7. By Product Type

• 7.1. Introduction
  • 7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
  • 7.1.2. Market Attractiveness Index, By Product Type
• 7.2. Kits *
  • 7.2.1. Introduction
  • 7.2.2. Market Size Analysis US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029
• 7.3. Reagents
  • 7.3.1. Probes/ Tags
  • 7.3.2. Enzyme
  • 7.3.3. Biotin
  • 7.3.4. Others
• 7.4. Services

8. By Labeling Type

• 8.1. Introduction
  • 8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Labeling Type
  • 8.1.2. Market Attractiveness Index, By Labeling Type
• 8.2. In-Vitro Labeling *
  • 8.2.1. Introduction
  • 8.2.2. Market Size Analysis US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029
• 8.3. In-Vivo Labeling
• 8.4. Bio-orthogonal Labeling

9. By Application

• 9.1. Introduction
  • 9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
  • 9.1.2. Market Attractiveness Index, By Application
• 9.2. Cell-Based Assay *
  • 9.2.1. Introduction
  • 9.2.2. Market Size Analysis US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029
• 9.3. Immunological Techniques
• 9.4. Protein Microarrays
• 9.5. Mass Spectroscopy
• 9.6. Fluorescence Microscopy

10. By End-User

• 10.1. Introduction
  • 10.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
  • 10.1.2. Market Attractiveness Index, By End-User
• 10.2. Hospitals *
  • 10.2.1. Introduction
  • 10.2.2. Market Size Analysis US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029
• 10.3. Research laboratories
• 10.4. Diagnostic centers
• 10.5. Others

11. By Region

• 11.1. Introduction
  • 11.1.1. Market Size Analysis US$ Million, 2020-2029 and Y-o-Y Growth Analysis (%), 2021-2029, By Region
  • 11.1.2. Market Attractiveness Index, By Region
• 11.2. North America
  • 11.2.1. Introduction
  • 11.2.2. Key Region-Specific Dynamics
  • 11.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
  • 11.2.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Labeling Type
  • 11.2.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
  • 11.2.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
  • 11.2.7. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
    • 11.2.7.1. U.S.
    • 11.2.7.2. Canada
    • 11.2.7.3. Mexico
• 11.3. Europe
  • 11.3.1. Introduction
  • 11.3.2. Key Region-Specific Dynamics
  • 11.3.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
  • 11.3.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Labeling Type
  • 11.3.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
  • 11.3.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
  • 11.3.7. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
    • 11.3.7.1. Germany
    • 11.3.7.2. U.K.
    • 11.3.7.3. France
    • 11.3.7.4. Italy
    • 11.3.7.5. Spain
    • 11.3.7.6. Rest of Europe
• 11.4. South America
  • 11.4.1. Introduction
  • 11.4.2. Key Region-Specific Dynamics
  • 11.4.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
  • 11.4.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Labeling Type
  • 11.4.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
  • 11.4.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
  • 11.4.7. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
    • 11.4.7.1. Brazil
    • 11.4.7.2. Argentina
    • 11.4.7.3. Rest of South America
• 11.5. Asia Pacific
  • 11.5.1. Introduction
  • 11.5.2. Key Region-Specific Dynamics
  • 11.5.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
  • 11.5.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Labeling Type
  • 11.5.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
  • 11.5.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
  • 11.5.7. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
    • 11.5.7.1. China
    • 11.5.7.2. India
    • 11.5.7.3. Japan
    • 11.5.7.4. Australia
    • 11.5.7.5. Rest of Asia Pacific
• 11.6. Middle East and Africa
  • 11.6.1. Introduction
  • 11.6.2. Key Region-Specific Dynamics
  • 11.6.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
  • 11.6.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Labeling Type
  • 11.6.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
  • 11.6.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User

12. Competitive Landscape

• 12.1. Key Developments and Strategies
• 12.2. Company Share Analysis
• 12.3. Products Benchmarking
• 12.4. List of Key Companies to Watch

13. Company Profiles

• 13.1. Thermo Fisher Scientific *
  • 13.1.1. Company Overview
  • 13.1.2. Product Portfolio and Description
  • 13.1.3. Key Highlights
  • 13.1.4. Financial Overview
• 13.2. Merck KGaA
• 13.3. PerkinElmer Inc.
• 13.4. GE Healthcare
• 13.5. Qiagen N.V.
• 13.6. New England Biolabs
• 13.7. SeraCare Life Sciences Inc.
• 13.8. Promega Corporation
• 13.9. Bio-Rad Laboratories, Inc.
• 13.10. Agilent Technologies

LIST NOT EXHAUSTIVE

14. Global Protein Labeling Market - DataM

• 14.1. Appendix
• 14.2. About Us and End-User
• 14.3. Contact Us