アトラセンタン市場：市場規模、予測、新たな洞察-2032年

アトラセンタンは、強力かつ選択的なエンドセリンA（ETA）受容体拮抗薬であり、IgA腎症（IgAN）やその他の蛋白尿性糸球体疾患などの複数の慢性腎疾患において、蛋白尿を減少させ、腎機能を維持する直接的な抗炎症作用や抗線維化作用を有することにより、利益をもたらす可能性があります。同社は2019年12月、糖尿病性腎臓病（DKD）治療薬としてアトラセンタンを開発していたAbbVieからアトラセンタンのライセンスを取得しました。

現在、同社は追加の蛋白尿性糸球体疾患を対象とした第II相（NCT04573920）AFFINITY試験で同剤を評価しています。このバスケット試験には、尿蛋白クレアチニン比（UPCR）が0.5～1.0g/g未満のIgAN患者、巣状分節性糸球体硬化症（FSGS）、アルポート症候群、糖尿病性腎臓病（DKD）の4つのコホートがあります。

当レポートでは、主要7ヶ国におけるアトラセンタン市場について調査し、市場の概要とともに、競合情勢、2032年までの市場規模予測、および国別市場分析などを提供しています。

目次

第1章 レポートのイントロダクション

第2章 アルポート症候群におけるアトラセンタンの概要

• 製品詳細
• 臨床開発
• その他の開発活動
• 製品プロファイル

第3章 競合情勢（上市済み治療法）

第4章 競合情勢（後期段階の新興治療法）

第5章 アトラセンタン市場評価

• アルポート症候群におけるアトラセンタンの市場展望
• 主要7ヶ国分析
• 国別市場分析
  • 米国
  • ドイツ
  • 英国

第6章 SWOT分析

第7章 アナリストの見解

第8章 付録

第9章 DelveInsightのサービス内容

第10章 免責事項

第11章 DelveInsightについて

第12章 レポート購入オプション

List of Tables

• Table 1: Atrasentan, Clinical Trial Description, 2023
• Table 2: Atrasentan, General Description
• Table 3: Competitive Landscape (Marketed Therapies)
• Table 4: Competitive Landscape (Emerging Therapies)
• Table 5: Atrasentan Market Size in the 7MM, in USD million (2019-2032)
• Table 6: Atrasentan Market Size in the US, in USD million (2019-2032)
• Table 7: Atrasentan Market Size in Germany, in USD million (2019-2032)
• Table 8: Atrasentan Market Size in France, in USD million (2019-2032)
• Table 9: Atrasentan Market Size in Italy, in USD million (2019-2032)
• Table 10: Atrasentan Market Size in Spain, in USD million (2019-2032)
• Table 11: Atrasentan Market Size in the UK, in USD million (2019-2032)
• Table 12: Atrasentan Market Size in Japan, in USD million (2019-2032)

List of Figures

• Figure 1: Atrasentan Market Size in the 7MM, USD million (2019-2032)
• Figure 2: Atrasentan Market Size in the United States, USD million (2019-2032)
• Figure 3: Atrasentan Market Size in Germany, USD million (2019-2032)
• Figure 4: Atrasentan Market Size in France, USD million (2019-2032)
• Figure 5: Atrasentan Market Size in Italy, USD million (2019-2032)
• Figure 6: Atrasentan Market Size in Spain, USD million (2019-2032)
• Figure 7: Atrasentan Market Size in the United Kingdom, USD million (2019-2032)
• Figure 8: Atrasentan Market Size in Japan, USD million (2019-2032)

"Atrasentan Market Size, Forecast, and Emerging Insight - 2032" report provides comprehensive insights about Atrasentan for Alport syndrome in the seven major markets. A detailed picture of the Atrasentan for Alport syndrome in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the Atrasentan for Alport syndrome. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the Atrasentan market forecast analysis for Alport syndrome in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in Alport syndrome.

Drug Summary:

Atrasentan is a potent and selective endothelin A (ETA) receptor antagonist that has the potential to provide benefit in multiple chronic kidney diseases such as IgA nephropathy (IgAN) and other proteinuric glomerular diseases by reducing proteinuria and having direct anti-inflammatory and anti-fibrotic effects to preserve kidney function. The company in-licensed atrasentan from AbbVie in December 2019, which previously developed atrasentan for diabetic kidney disease (DKD).

Currently, the company is evaluating the drug in Phase II (NCT04573920) AFFINITY study in additional proteinuric glomerular diseases. The basket trial has four cohorts consisting of patients with IgAN with urine protein to creatinine ratio (UPCR) of 0.5 to less than 1.0 g/g, focal segmental glomerulosclerosis (FSGS), Alport syndrome, and diabetic kidney disease (DKD).

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the Atrasentan description, mechanism of action, dosage and administration, research and development activities in Alport syndrome.
• Elaborated details on Atrasentan regulatory milestones and other development activities have been provided in this report.
• The report also highlights the Atrasentan research and development activities in Alport syndrome across the United States, Europe, and Japan.
• The report also covers the patents information with expiry timeline around Atrasentan.
• The report contains forecasted sales of Atrasentan for Alport syndrome till 2032.
• Comprehensive coverage of the late-stage emerging therapies for Alport syndrome.
• The report also features the SWOT analysis with analyst views for Atrasentan in Alport syndrome.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

Atrasentan Analytical Perspective by DelveInsight

• In-depth Atrasentan Market Assessment

This report provides a detailed market assessment of Atrasentan for Alport syndrome in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2027 to 2032.

• Atrasentan Clinical Assessment

The report provides the clinical trials information of Atrasentan for Alport syndrome covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for Alport syndrome is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence Atrasentan dominance.
• Other emerging products for Alport syndrome are expected to give tough market competition to Atrasentan and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of Atrasentan in Alport syndrome.
• Our in-depth analysis of the forecasted sales data of Atrasentan from 2027 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the Atrasentan in Alport syndrome.

Key Questions:

• What is the product type, route of administration and mechanism of action of Atrasentan?
• What is the clinical trial status of the study related to Atrasentan in Alport syndrome and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the Atrasentan development?
• What are the key designations that have been granted to Atrasentan for Alport syndrome?
• What is the forecasted market scenario of Atrasentan for Alport syndrome?
• What are the forecasted sales of Atrasentan in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain) and the United Kingdom, and Japan?
• What are the other emerging products available and how are these giving competition to Atrasentan for Alport syndrome?
• Which are the late-stage emerging therapies under development for the treatment of Alport syndrome?

Table of Contents

1. Report Introduction

2. Atrasentan Overview in Alport syndrome

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and efficacy
• 2.3. Other Developmental Activities
• 2.4. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. Atrasentan Market Assessment

• 5.1. Market Outlook of Atrasentan in Alport syndrome
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of Atrasentan in the 7MM for Alport syndrome
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of Atrasentan in the United States for Alport syndrome
  • 5.3.2. Market Size of Atrasentan in Germany for Alport syndrome
  • 5.3.3. Market Size of Atrasentan in France for Alport syndrome
  • 5.3.4. Market Size of Atrasentan in Italy for Alport syndrome
  • 5.3.5. Market Size of Atrasentan in Spain for Alport syndrome
  • 5.3.6. Market Size of Atrasentan in the United Kingdom for Alport syndrome
  • 5.3.7. Market Size of Atrasentan in Japan for Alport syndrome

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options