CVN-424の市場規模、予測、新薬の考察（2032年）

薬剤のサマリー

CVN-424は、パーキンソン病治療薬として開発中の新規ターゲット（GPR6）に作用するファーストインクラスの経口非ドパミン作動性化合物です。パーキンソン病に関連するD2受容体依存的で間接的な経路を選択的に標的とし、パーキンソン病の現在の標準治療であるレボドパと脳深部刺激療法の効果を、副作用なしに得ることを目的としています。CVN424は、パーキンソン病患者を対象としたフェーズII試験において、臨床的に意義のある有意な有効性を示しました。さらに企業は、レボドパによる治療を受けていない新たに診断されたパーキンソン病患者を対象に、単剤療法としてのCVN424を評価するフェーズII概念実証試験を2023年第2四半期に開始する予定であり、また、補助療法としての承認取得を目指し、本薬をさらに評価するフェーズII/III臨床試験を開始する予定です。

当レポートでは、主要7市場（米国・ドイツ・フランス・イタリア・スペイン・英国・日本）におけるパーキンソン病向けCVN-424について調査分析し、作用機序、用法と用量、研究開発活動についての考察、収益の予測などを提供しています。

目次

第1章 レポートのイントロダクション

第2章 パーキンソン病におけるCVN-424の概要

• 製品の詳細
• 臨床開発
  • 臨床研究
  • 臨床試験情報
  • 安全性と有効性
• その他の開発活動
• 製品プロファイル

第3章 競合情勢（上市済みの治療法）

第4章 競合情勢（後期の新治療法）

第5章 CVN-424市場の評価

• パーキンソン病におけるCVN-424の市場見通し
• 主要7市場の分析
  • 主要7市場のパーキンソン病向けCVN-424の市場規模
• 市場の分析：国別
  • 米国のパーキンソン病向けCVN-424の市場規模
  • ドイツのパーキンソン病向けCVN-424の市場規模
  • 英国のパーキンソン病向けCVN-424の市場規模

第6章 SWOT分析

第7章 アナリストの見解

第8章 付録

第9章 DelveInsightのサービス内容

第10章 免責事項

第11章 DelveInsightについて

第12章 レポート購入オプション

List of Tables

• Table 1: CVN-424, Clinical Trial Description, 2023
• Table 2: CVN-424, General Description
• Table 3: Competitive Landscape (Marketed Therapies)
• Table 4: Competitive Landscape (Late-stage Emerging Therapies)
• Table 5: CVN-424 Market Size in the 7MM, in USD million (2019-2032)
• Table 6: CVN-424 Market Size in the US, in USD million (2019-2032)
• Table 7: CVN-424 Market Size in Germany, in USD million (2019-2032)
• Table 8: CVN-424 Market Size in France, in USD million (2019-2032)
• Table 9: CVN-424 Market Size in Italy, in USD million (2019-2032)
• Table 10: CVN-424 Market Size in Spain, in USD million (2019-2032)
• Table 11: CVN-424 Market Size in the UK, in USD million (2019-2032)
• Table 12: CVN-424 Market Size in Japan, in USD million (2019-2032)

List of Figures

• Figure 1: CVN-424 Market Size in the 7MM, USD million (2019-2032)
• Figure 2: CVN-424 Market Size in the United States, USD million (2019-2032)
• Figure 3: CVN-424 Market Size in Germany, USD million (2019-2032)
• Figure 4: CVN-424 Market Size in France, USD million (2019-2032)
• Figure 5: CVN-424 Market Size in Italy, USD million (2019-2032)
• Figure 6: CVN-424 Market Size in Spain, USD million (2019-2032)
• Figure 7: CVN-424 Market Size in the United Kingdom, USD million (2019-2032)
• Figure 8: CVN-424 Market Size in Japan, USD million (2019-2032)

"CVN-424 Market Size, Forecast, and Emerging Insight - 2032" report provides comprehensive insights about CVN-424 for Parkinson's disease in the seven major markets. A detailed picture of the CVN-424 for Parkinson's Disease in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the CVN-424 for Parkinson's Disease. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the CVN-424 market forecast analysis for Parkinson's disease in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in Parkinson's disease.

Drug Summary:

CVN-424, Cerevance's lead therapeutic, is a first-in-class, oral, non-dopaminergic compound acting on a novel target (GPR6) in development for the treatment of Parkinson's disease. It selectively targets the D2 receptor-dependent, indirect pathway associated with Parkinson's disease and is intended to generate the positive effects of levodopa and deep brain stimulation, the current standard of care for Parkinson's disease, without the adverse effects. CVN424 demonstrated significant and clinically meaningful efficacy in a Phase II study in patients with Parkinson's disease. Additionally, the company planned to initiate a Phase II proof of concept study assessing CVN424 as a monotherapy treatment in patients with newly diagnosed Parkinson's disease not yet treated with levodopa in Q2 2023 and Phase II/III clinical study to further assess the drug with intentions of seeking regulatory approval as an adjunctive therapy.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the CVN-424 description, mechanism of action, dosage and administration, research and development activities in Parkinson's disease.
• Elaborated details on CVN-424 regulatory milestones and other development activities have been provided in this report.
• The report also highlights the CVN-424 research and development activities in Parkinson's disease across the United States, Europe and Japan.
• The report also covers the patents information with expiry timeline around CVN-424.
• The report contains forecasted sales of CVN-424 for Parkinson's disease till 2032.
• Comprehensive coverage of the late-stage emerging therapies for Parkinson's disease.
• The report also features the SWOT analysis with analyst views for CVN-424 in Parkinson's disease.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

CVN-424 Analytical Perspective by DelveInsight

• In-depth CVN-424 Market Assessment

This report provides a detailed market assessment of CVN-424 for Parkinson's disease in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2026 to 2032.

• CVN-424 Clinical Assessment

The report provides the clinical trials information of CVN-424 for Parkinson's disease covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for Parkinson's disease is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence CVN-424 dominance.
• Other emerging products for Parkinson's disease are expected to give tough market competition to CVN-424 and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of CVN-424 in Parkinson's disease.
• Our in-depth analysis of the forecasted sales data of CVN-424 from 2026 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the CVN-424 in Parkinson's disease.

Key Questions:

• What is the product type, route of administration and mechanism of action of CVN-424?
• What is the clinical trial status of the study related to CVN-424 in Parkinson's disease and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the CVN-424 development?
• What are the key designations that have been granted to CVN-424 for Parkinson's disease?
• What is the forecasted market scenario of CVN-424 for Parkinson's disease?
• What are the forecasted sales of CVN-424 in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how are these giving competition to CVN-424 for Parkinson's disease?
• Which are the late-stage emerging therapies under development for the treatment of Parkinson's disease?

Table of Contents

1. Report Introduction

2. CVN-424 Overview in Parkinson's disease

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and Efficacy
• 2.3. Other Developmental Activities
• 2.4. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. CVN-424 Market Assessment

• 5.1. Market Outlook of CVN-424 in Parkinson's disease
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of CVN-424 in the 7MM for Parkinson's disease
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of CVN-424 in the United States for Parkinson's disease
  • 5.3.2. Market Size of CVN-424 in Germany for Parkinson's disease
  • 5.3.3. Market Size of CVN-424 in France for Parkinson's disease
  • 5.3.4. Market Size of CVN-424 in Italy for Parkinson's disease
  • 5.3.5. Market Size of CVN-424 in Spain for Parkinson's disease
  • 5.3.6. Market Size of CVN-424 in the United Kingdom for Parkinson's disease
  • 5.3.7. Market Size of CVN-424 in Japan for Parkinson's disease

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options