Product Code: DIDM1174
"Zilovertamab vedotin Emerging Drug Insight and Market Forecast - 2032" report provides comprehensive insights about zilovertamab vedotin for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets. A detailed picture of the zilovertamab vedotin for DLBCL in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the zilovertamab vedotin for DLBCL. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the zilovertamab vedotin market forecast analysis for DLBCL in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in DLBCL.
Drug Summary:
Zilovertamab vedotin (ZV; MK-2140, previously known as VLS-101) is a novel antibody-drug conjugate comprising the humanized monoclonal antibody zilovertamab, which is highly specific for tumor tissue; a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker; and the antimicrotubule cytotoxin monomethyl auristatin E (linker-monomethyl auristatin E designated as vedotin). Zilovertamab vedotin binding to tumor cell ROR1 results in rapid internalization, trafficking to lysosomes, antibody-drug conjugate cleavage, and monomethyl auristatin E release.
The company is currently conducting a two-part (Part 1, dose confirmation; Part 2, dose expansion), open-label, randomized, active-control, Phase II/III study (NCT05139017), which will assess safety and efficacy of ZV + standard of care in patients with R/R DLBCL.
Scope of the Report:
The report provides insights into:
- A comprehensive product overview including the zilovertamab vedotin description, mechanism of action, dosage and administration, research and development activities in Diffuse Large B-cell lymphoma (DLBCL).
- Elaborated details on zilovertamab vedotin regulatory milestones and other development activities have been provided in this report.
- The report also highlights the zilovertamab vedotin research and development activities in DLBCL across the United States, Europe and Japan.
- The report also covers the patents information with expiry timeline around zilovertamab vedotin.
- The report contains forecasted sales of zilovertamab vedotin for DLBCL till 2032.
- Comprehensive coverage of the late-stage emerging therapies for DLBCL.
- The report also features the SWOT analysis with analyst views for zilovertamab vedotin in DLBCL.
Methodology:
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
Zilovertamab vedotin Analytical Perspective by DelveInsight
In-depth Zilovertamab vedotin Market Assessment
This report provides a detailed market assessment of zilovertamab vedotin for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2025 to 2032.
Zilovertamab vedotin Clinical Assessment
The report provides the clinical trials information of zilovertamab vedotin for DLBCL covering trial interventions, trial conditions, trial status, start and completion dates.
Report Highlights:
- In the coming years, the market scenario for Diffuse Large B-cell lymphoma (DLBCL) is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
- The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence zilovertamab vedotin dominance.
- Other emerging products for DLBCL are expected to give tough market competition to zilovertamab vedotin and launch of late-stage emerging therapies in the near future will significantly impact the market.
- A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of zilovertamab vedotin in DLBCL.
- Our in-depth analysis of the forecasted sales data of zilovertamab vedotin from 2025 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the zilovertamab vedotin in DLBCL.
Key Questions:
- What is the product type, route of administration and mechanism of action of zilovertamab vedotin?
- What is the clinical trial status of the study related to zilovertamab vedotin in Diffuse Large B-cell lymphoma (DLBCL) and study completion date?
- What are the key collaborations, mergers and acquisitions, licensing and other activities related to the zilovertamab vedotin development?
- What are the key designations that have been granted to zilovertamab vedotin for DLBCL?
- What is the forecasted market scenario of zilovertamab vedotin for DLBCL?
- What are the forecasted sales of zilovertamab vedotin in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
- What are the other emerging products available and how are these giving competition to zilovertamab vedotin for DLBCL?
- Which are the late-stage emerging therapies under development for the treatment of DLBCL?
Table of Contents
1. Report Introduction
2. Zilovertamab vedotin Overview in DLBCL
- 2.1. Product Detail
- 2.2. Clinical Development
- 2.2.1. Clinical studies
- 2.2.2. Clinical trials information
- 2.2.3. Safety and efficacy
- 2.3. Other Developmental Activities
- 2.4. Product Profile
3. Competitive Landscape (Marketed Therapies)
4. Competitive Landscape (Late-stage Emerging Therapies)
5. Zilovertamab vedotin Market Assessment
- 5.1. Market Outlook of Zilovertamab vedotin in DLBCL
- 5.2. 7MM Analysis
- 5.2.1. Market Size of Zilovertamab vedotin in the 7MM for DLBCL
- 5.3. Country-wise Market Analysis
- 5.3.1. Market Size of Zilovertamab vedotin in the United States for DLBCL
- 5.3.2. Market Size of Zilovertamab vedotin in Germany for DLBCL
- 5.3.3. Market Size of Zilovertamab vedotin in France for DLBCL
- 5.3.4. Market Size of Zilovertamab vedotin in Italy for DLBCL
- 5.3.5. Market Size of Zilovertamab vedotin in Spain for DLBCL
- 5.3.6. Market Size of Zilovertamab vedotin in the United Kingdom for DLBCL
- 5.3.7. Market Size of Zilovertamab vedotin in Japan for DLBCL
6. SWOT Analysis
7. Analysts' Views
8. Appendix
- 8.1. Bibliography
- 8.2. Report Methodology
9. DelveInsight Capabilities
10. Disclaimer
11. About DelveInsight
12. Report Purchase Options