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市場調査レポート
商品コード
1381107
EO2401新薬の考察と市場予測 - 2032年EO 2401 Emerging Drug Insight and Market Forecast - 2032 |
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カスタマイズ可能
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EO2401新薬の考察と市場予測 - 2032年 |
出版日: 2023年11月01日
発行: DelveInsight
ページ情報: 英文 30 Pages
納期: 1~3営業日
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当レポートでは、主要7市場(米国、ドイツ、フランス、イタリア、スペイン、英国、日本)におけるEO2401について調査分析し、作用機序、用法と用量、研究開発活動に関する考察や、市場予測などを提供しています。
“"EO 2401 Emerging Drug Insight and Market Forecast - 2032" report provides comprehensive insights about EO 2401 for glioblastoma multiforme (GBM) in the seven major markets. A detailed picture of the EO 2401 for GBM in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the EO 2401 for GBM. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the EO 2401 market forecast analysis for GBM in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in GBM.
A donor-derived, off-the-shelf, microbiome therapeutic cancer peptide vaccine composed of three bacterial Oncomimics, immunogenic microbiome-derived peptides that are highly homologous to tumor-associated antigens (TAAs), that are obtained and selected from the human gut microbiome and are specific for brain tumors, including GBM, with potential immunomodulating and antineoplastic activities. The three microbiome-derived bacterial antigens in EO2401 mimic three TAAs that are highly expressed by brain tumors. Upon administration of microbiome-derived peptide vaccine EO2401, the peptides are taken up and presented on dendritic cells (DCs) to T cells. As the presented antigens display molecular mimicry with selected TAAs on brain cancer cells, a memory T-cell- and cytotoxic T-lymphocyte (CTL)-mediated immune response may be mounted against the TAAs expressed on the brain cancer cells, thereby eradicating the brain cancer cells. EO2401 in combination with an immune checkpoint inhibitor (nivolumab, OPDIVO) ± bevacizumab for treating patients with first progression/recurrence of GBM. EO2401 is Enterome's first-in-class off-the-shelf OncoMimics cancer immunotherapy. It combines three OncoMimics peptides that closely mimic IL13Ra2, BIRC5, and FOXM1, all known driver antigens on aggressive solid tumors. In addition, EO2401 contains a CD4 helper peptide UCP2. Enterome selected these OncoMimics peptides using its Mimicry platform, which applies best-in-class biocomputational tools and bioassays to identify novel therapeutics from its proprietary database of 20+ million bioactive gut microbiome peptides and proteins. The study aims to assess the safety, tolerability, immunogenicity, and preliminary efficacy of the combination in approximately 100 patients enrolled at 10 clinical sites in Europe and the US.
The report provides insights into:
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
This report provides a detailed market assessment of EO 2401 for glioblastoma multiforme (GBM) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2028 to 2032.
The report provides the clinical trials information of EO 2401 for GBM covering trial interventions, trial conditions, trial status, start and completion dates.