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市場調査レポート
商品コード
1355788
うっ血性心不全(CHF)市場- 成長、将来展望、競合分析、2023~2031年Congestive Heart Failure (CHF) Market - Growth, Future Prospects and Competitive Analysis, 2023 - 2031 |
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うっ血性心不全(CHF)市場- 成長、将来展望、競合分析、2023~2031年 |
出版日: 2023年09月07日
発行: Acute Market Reports
ページ情報: 英文 119 Pages
納期: 即日から翌営業日
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うっ血性心不全(CHF)は心不全としても知られ、血液を効率的に送り出す心臓の能力が低下する慢性的な病状です。この病態は、心臓の筋肉が弱くなったり損傷したりすることで、体の必要量を満たすための酸素を含んだ血液の供給が不十分になることで起こります。その結果、体内のさまざまな部位に水分がたまり、息切れ、疲労、足や足首のむくみ(浮腫)、身体活動の困難などの症状が現れます。うっ血性心不全治療薬市場は、2023年から2031年の予測期間中にCAGR 14.5%で成長すると予想されます。心臓疾患の蔓延と医療技術の進歩が相まって、効果的なCHF治療薬への需要が維持されるであろう。規制上の課題は今後も続き、企業は複雑な承認プロセスを乗り切る必要があります。多様な患者のニーズに対応するためには、クラス別および販売チャネル別の市場セグメンテーションが引き続き重要です。
CHF治療薬市場の主な促進要因のひとつは、世界の心臓病有病率の上昇です。世界保健機関(WHO)は、心血管疾患を世界の死亡原因の第一位としています。うっ血性心不全の罹患率の増加は、座りがちなライフスタイルや食生活の乱れといった要因によって悪化しており、効果的な治療オプションに対する需要が大幅に高まっています。人口の高齢化に伴い、心臓関連の病気の負担は増加し、市場の成長をさらに促進すると予測されています。
CHF治療の状況は、医療技術の進歩によって一変しました。ドラッグデリバリーシステム、個別化医療アプローチ、新規化合物の開発における革新は、患者の転帰を著しく改善しました。特に、サクビトリル/バルサルタン(エントレスト)のイントロダクションは、駆出率が低下した心不全の管理に画期的な進歩をもたらしました。このような進歩は、治療の有効性を高めるだけでなく、医療従事者や患者が利用できる治療の選択肢を拡大しました。
心臓疾患の早期診断とタイムリーな治療を促進する取り組みは、CHF治療薬市場にプラスの影響を与えています。ヘルスケア機関や政府による心臓の健康や早期介入の利点に関する意識向上への取り組みが、患者の意識向上につながっています。心不全を早期に発見することで、医療従事者は病気の進行を防ぎ、生活の質全体を向上させる治療戦略を実施することができます。このような努力の積み重ねが、CHF治療薬の需要を押し上げています。
CHF治療薬市場は成長を遂げる一方で、厳しい規制要件がもたらす課題にも遭遇しています。新薬の開発と承認取得のプロセスは複雑で時間がかかります。FDAやEMAなどの規制機関は、新薬候補に厳格な安全性と有効性の基準を課しており、開発期間の長期化とコストの上昇を招いています。規制状況を乗り切ることは、中小の製薬会社にとっては特に困難であり、市場成長の抑制要因となっています。
2022年には、アンジオテンシン2受容体拮抗薬(ARB)が最も高い売上を記録しました。アンジオテンシン2受容体拮抗薬は、血管の収縮や体液貯留を引き起こすホルモンであるアンジオテンシンIIの作用を阻害することで効果を発揮する薬物です。これらの作用を阻害することで、ARBは血管を弛緩させ、血圧を下げ、心臓の負担を軽減します。ARBはCHFや高血圧などの関連疾患の管理によく処方されます。ACE阻害薬、β遮断薬、利尿薬などの他の薬剤と併用されることも多く、心不全患者に対する包括的な治療が行われます。これらの薬剤は症状を改善し、心臓のポンプ機能を高め、全体としてより良い病態管理に貢献します。アンジオテンシン2受容体拮抗薬は、その確立された有効性と広範な使用により、これまでCHF治療薬市場で大きな収益をあげてきました。アンジオテンシン2受容体拮抗薬は、心不全治療の様々な局面に対応できることから、多くの患者にとって治療レジメンの重要な構成要素となっています。しかし、各薬剤クラスが生み出す収益は、市場力学、価格設定、患者の嗜好、新しい治療選択肢の出現などの要因によって変動する可能性があることに留意することが重要です。
2022年には、病院薬局が最も高い売上を記録しました。病院内薬局は、入院患者と外来患者の両方に薬を調剤する病院内のヘルスケア施設です。これらの薬局は、CHFを含む急性疾患の患者に必要不可欠な医薬品への即時アクセスを提供するという重要な役割を担っています。病院内の薬局では、心不全治療薬を含む幅広い種類の薬剤を扱っていることが多く、医療専門家の監督のもと、患者が適切な薬剤と用量を受け取れるようにしています。重症の心不全やその合併症で入院している患者さんには、直接静脈内注射や筋肉内注射が行われることもあり、病院内薬局はそのような患者さんにも対応しています。
CHF治療薬市場の地理的動向は、地域によって異なるパターンを示しています。CAGRが最も高い地域はアジア太平洋で、医療インフラ整備の進展、高齢者人口の増加、高血圧や糖尿病などの危険因子の蔓延といった要因が複合的に作用しています。北米は、確立されたヘルスケアシステム、多額の医療費、研究開発活動への重点的な取り組みにより、常に最高の売上シェアを維持しています。
競合情勢が激しいCHF治療薬市場において、大手企業は市場での存在感を維持し、イノベーションを推進するために様々な戦略を採用しています。Bayer AG、Novartis AG、Merck &co., Inc.、Astrazeneca、Bristol-Myers Squibb Company、Amgen Inc.、BoehringerIngelheiminternationalGmbh、Pfizer, Inc.、Johnson &Johnson Services, Inc.、大塚製薬株式会社、Eli Lilly and Company、Novo Nordiska/Sのような注目すべき企業は、ポートフォリオを拡大し、市場でのリーチを強化するために、合併、買収、提携、製品発売を進めてきました。これらの企業はまた、精密治療、個別化医療アプローチ、患者転帰の改善に焦点を当てた研究開発にも多額の投資を行っています。
FIG. 9Market Positioning of Key Congestive Heart Failure (CHF) Market Players, 2022
FIG. 10Global Congestive Heart Failure (CHF) Market - Tier Analysis - Percentage of Revenues by Tier Level, 2022 Versus 2031
Congestive heart failure (CHF), also known as heart failure, is a chronic medical condition in which the heart's ability to pump blood efficiently is compromised. This condition occurs when the heart muscles become weakened or damaged, leading to an inadequate supply of oxygenated blood to meet the body's needs. As a result, fluid may accumulate in various parts of the body, causing symptoms such as shortness of breath, fatigue, swelling in the legs and ankles (edema), and difficulty performing physical activities. The congestive heart failure drug market is expected to grow at a CAGR of 14.5% during the forecast period of 2023 to 2031. The prevalence of heart diseases, coupled with ongoing advancements in medical technology, will sustain the demand for effective CHF treatments. Regulatory challenges will persist, requiring companies to navigate complex approval processes. Market segmentation by class and distribution channels will remain instrumental in catering to diverse patient needs.
One of the primary drivers of the CHF drugs market is the escalating prevalence of heart diseases worldwide. The World Health Organization (WHO) has identified cardiovascular diseases as the leading cause of mortality globally. The growing incidence of congestive heart failure, exacerbated by factors like sedentary lifestyles and poor dietary habits, has substantially increased the demand for effective treatment options. As the population ages, the burden of heart-related ailments is projected to rise, further fueling the market's growth.
The landscape of CHF treatment has been revolutionized by advancements in medical technology. Innovations in drug delivery systems, personalized medicine approaches, and the development of novel drug compounds have significantly improved patient outcomes. Notably, the introduction of sacubitril/valsartan (Entresto) has marked a breakthrough in managing heart failure with reduced ejection fraction. Such advancements have not only enhanced the efficacy of treatments but have also expanded the treatment options available to healthcare providers and patients.
Efforts to promote early diagnosis and timely treatment of heart conditions have had a positive impact on the CHF drugs market. Initiatives by healthcare organizations and governments to raise awareness about heart health and the benefits of early intervention have led to increased patient awareness. By identifying heart failure in its early stages, medical professionals can implement treatment strategies that prevent disease progression and improve overall quality of life. These efforts have collectively driven the demand for CHF drugs.
While the CHF drugs market has experienced growth, it has also encountered challenges posed by stringent regulatory requirements. The process of developing and gaining approval for new drugs is complex and time-consuming. Regulatory agencies such as the FDA and EMA impose rigorous safety and efficacy standards on new drug candidates, leading to prolonged development timelines and elevated costs. Navigating the regulatory landscape can be particularly challenging for smaller pharmaceutical companies, acting as a restraint on market growth.
In 2022, Angiotensin 2 Receptor Blockers (ARBs) held highest revenue. Angiotensin 2 Receptor Blockers are a class of medications that work by blocking the effects of the hormone angiotensin II, which can lead to blood vessel constriction and fluid retention. By blocking these effects, ARBs help relax blood vessels, reduce blood pressure, and decrease the workload on the heart. ARBs are commonly prescribed to manage CHF and related conditions, such as hypertension. They are often used in combination with other medications, such as ACE inhibitors, beta blockers, and diuretics, to provide comprehensive treatment for heart failure patients. These medications can help improve symptoms, enhance the heart's pumping efficiency, and overall contribute to better management of the condition. Due to their established efficacy and widespread use, Angiotensin 2 Receptor Blockers have historically generated substantial revenue in the CHF drugs market. Their ability to address multiple aspects of heart failure management makes them a critical component of treatment regimens for many patients. However, it's important to note that the revenue generated by each drug class can vary based on factors such as market dynamics, pricing, patient preferences, and the emergence of newer treatment options.
In 2022, Hospital Pharmacies held highest revenue. Hospital Pharmacies are healthcare facilities within hospitals that dispense medications to both inpatients and outpatients. These pharmacies play a crucial role in providing immediate access to essential medications for patients with acute conditions, including CHF. Hospital Pharmacies often have a wide range of medications available, including those for treating heart failure, and they ensure that patients receive the right medications and dosages under the supervision of healthcare professionals. Patients hospitalized due to severe CHF or related complications may have their medications administered directly through intravenous (IV) or intramuscular (IM) injections, which are facilitated by Hospital Pharmacies.
The geographic trends in the CHF drugs market reveal varying patterns across regions. The region with the highest CAGR is Asia-Pacific, driven by a combination of factors such as increasing healthcare infrastructure development, a rising geriatric population, and the prevalence of risk factors like hypertension and diabetes. North America has consistently held the highest revenue share, attributed to its well-established healthcare systems, significant healthcare expenditure, and a robust focus on research and development activities.
In the fiercely Competitive Landscape of the CHF drugs market, leading players have adopted diverse strategies to maintain their market presence and drive innovation. Notable players like Bayer AG,Novartis AG, Merck & co., Inc., Astrazeneca, Bristol-Myers Squibb Company, Amgen Inc., BoehringerIngelheiminternationalGmbh, Pfizer, Inc., Johnson & Johnson Services, Inc., Otsuka Pharmaceutical Co., Ltd., Eli Lilly and Company, and Novo Nordiska/S have pursued mergers, acquisitions, collaborations, and product launches to expand their portfolios and enhance their market reach. These companies are also investing heavily in research and development endeavors, focusing on precision therapies, personalized medicine approaches, and improved patient outcomes.
This study report represents analysis of each segment from 2021 to 2031 considering 2022 as the base year. Compounded Annual Growth Rate (CAGR) for each of the respective segments estimated for the forecast period of 2023 to 2031.
The current report comprises of quantitative market estimations for each micro market for every geographical region and qualitative market analysis such as micro and macro environment analysis, market trends, competitive intelligence, segment analysis, porters five force model, top winning strategies, top investment markets, emerging trends and technological analysis, case studies, strategic conclusions and recommendations and other key market insights.
The complete research study was conducted in three phases, namely: secondary research, primary research, and expert panel review. key data point that enables the estimation ofCongestive Heart Failure (CHF) market are as follows:
Micro and macro environment factors that are currently influencing the Congestive Heart Failure (CHF) market and their expected impact during the forecast period.
Market forecast was performed through proprietary software that analyzes various qualitative and quantitative factors. Growth rate and CAGR were estimated through intensive secondary and primary research. Data triangulation across various data points provides accuracy across various analyzed market segments in the report. Application of both top down and bottom-up approach for validation of market estimation assures logical, methodical and mathematical consistency of the quantitative data.