チェックポイント阻害剤難治性がん市場 - 世界の産業規模、シェア、動向、機会、予測：タイプ別、用途別、地域別、競合別、2020年～2030年

世界のチェックポイント阻害剤難治性がんの市場規模は、2024年に324億9,000万米ドルとなり、予測期間中のCAGRは8.49%で、2030年までには524億米ドルに達すると予測されています。

世界のチェックポイント阻害剤難治性がん市場は、従来のチェックポイント阻害療法に反応しないがんをターゲットとする、がん業界における新たなセグメントです。PD-1、PD-L1、CTLA-4などの免疫チェックポイントタンパク質を阻害するチェックポイント阻害剤は、さまざまながんの治療で大きな成功を収めています。世界保健機関（WHO）によれば、がんは依然として世界の死因の上位を占めており、2020年には約1,000万人が死亡すると報告されています。このようながん罹患率の増加と診断法の進歩が相まって、より効果的な治療に対する需要が高まっています。

チェックポイント阻害剤に対する耐性が広まるにつれ、そのメカニズムの解明に注目が集まっています。治療抵抗性を克服し、難治性がん患者の予後を改善するために、チェックポイント阻害剤と他の治療法（標的療法、免疫療法の追加、化学療法、放射線療法など）との併用療法が研究されています。

しかし、チェックポイント阻害剤や併用療法は高額であるため、特に特定の地域では、治療へのアクセスが制限される可能性があります。さらに、免疫関連の有害事象（irAEs）が課題となっており、慎重な管理が必要とされ、治療方針の決定に影響を与えています。このようなハードルがあるにもかかわらず、現在進行中の調査、世界のがん罹患率の上昇、耐性がんに対するより効果的な治療法への需要により、チェックポイント阻害剤難治性がん市場は成長に向かっています。免疫抵抗性メカニズムの解明が進むにつれ、併用療法や次世代免疫療法ががん治療の変革に重要な役割を果たすと期待されています。開発パイプラインには多額の投資が行われており、市場は長期的な可能性を秘めていますが、コスト、アクセス性、有効性に関する課題は残されています。

主要な市場促進要因

免疫療法研究の急速な進展

腫瘍微小環境に対する理解の深まり

政府の取り組みと規制当局の支援

主要な市場課題

腫瘍の本質的な不均一性

限られたバイオマーカー検証

主要な市場動向

併用療法と相乗的アプローチ

腫瘍微小環境調節への注力

目次

第1章 製品概要

第2章 調査手法

第3章 エグゼクティブサマリー

第4章 顧客の声

第5章 世界のチェックポイント阻害剤難治性がん市場展望

• 市場規模・予測
  • 金額別
• 市場シェア・予測
  • タイプ別（PD-1阻害剤、PD-L1阻害剤、その他）
  • 用途別（肺がん、膀胱がん、黒色腫、ホジキンリンパ腫、その他）
  • 地域別（北米、欧州、アジア太平洋、南米、中東・アフリカ）
  • 企業別（2024年）
• 市場マップ
• タイプ別
• 用途別
• 地域別

第6章 北米のチェックポイント阻害剤難治性がん市場展望

• 市場規模・予測
  • 金額別
• 市場シェア・予測
  • タイプ別
  • 用途別
  • 国別
• 北米：国別分析
  • 米国
  • カナダ
  • メキシコ

第7章 欧州のチェックポイント阻害剤難治性がん市場展望

• 市場規模・予測
  • 金額別
• 市場シェア・予測
  • タイプ別
  • 用途別
  • 国別
• 欧州：国別分析
  • フランス
  • ドイツ
  • 英国
  • イタリア
  • スペイン

第8章 アジア太平洋のチェックポイント阻害剤難治性がん市場展望

• 市場規模・予測
  • 金額別
• 市場シェア・予測
  • タイプ別
  • 用途別
  • 国別
• アジア太平洋：国別分析
  • 中国
  • インド
  • 日本
  • 韓国
  • オーストラリア

第9章 南米のチェックポイント阻害剤難治性がん市場展望

• 市場規模・予測
  • 金額別
• 市場シェア・予測
  • タイプ別
  • 用途別
  • 国別
• 南米：国別分析
  • ブラジル
  • アルゼンチン
  • コロンビア

第10章 中東・アフリカのチェックポイント阻害剤難治性がん市場展望

• 市場規模・予測
  • 金額別
• 市場シェア・予測
  • タイプ別
  • 用途別
  • 国別
• 中東・アフリカ：国別分析
  • 南アフリカ
  • サウジアラビア
  • アラブ首長国連邦

第11章 市場力学

• 促進要因
• 課題

第12章 市場動向と発展

• 最近の動向
• 合併と買収
• 製品上市

第13章 世界のチェックポイント阻害剤難治性がん市場：SWOT分析

第14章 ポーターのファイブフォース分析

• 業界内の競合
• 新規参入の可能性
• サプライヤーの力
• 顧客の力
• 代替品の脅威

第15章 競合情勢

• Bristol-Myers Squibb Company.
• AstraZeneca plc.
• Merck KGaA
• F. Hoffmann-La Roche Ltd
• Regeneron Pharmaceuticals Inc
• Pfizer Inc
• Janssen Global Services, LLC
• 4SC AG
• Mirati Therapeutics, Inc.
• Ascentage Pharma.

第16章 戦略的提言

第17章 調査会社について・免責事項

Global Checkpoint Inhibitor Refractory Cancer Market was valued at USD 32.49 Billion in 2024 and is expected to reach USD 52.40 Billion by 2030 with a CAGR of 8.49% during the forecast period. The global checkpoint inhibitor refractory cancer market is an emerging segment in the oncology industry, targeting cancers that do not respond to traditional checkpoint inhibitor therapies. Checkpoint inhibitors, which block immune checkpoint proteins like PD-1, PD-L1, and CTLA-4, have shown considerable success in treating a range of cancers. Cancer continues to be a leading cause of death worldwide, with nearly 10 million deaths reported in 2020, according to the World Health Organization. This growing cancer incidence, coupled with advancements in diagnostics, has increased the demand for more effective treatments.

As resistance to checkpoint inhibitors becomes more prevalent, there is a heightened focus on understanding the mechanisms behind this resistance. Researchers are exploring combination therapies that pair checkpoint inhibitors with other treatment modalities, including targeted therapies, additional immunotherapies, chemotherapy, and radiation, in an effort to overcome resistance and improve outcomes for refractory cancer patients.

However, the high cost of checkpoint inhibitors and combination therapies can limit access, particularly in certain regions. Additionally, immune-related adverse events (irAEs) pose a challenge, requiring careful management and impacting treatment decisions. Despite these hurdles, the checkpoint inhibitor refractory cancer market is set for growth, driven by ongoing research, the rising global cancer burden, and the demand for more effective therapies for resistant cancers. As the understanding of immune resistance mechanisms continues to evolve, combination therapies and next-generation immunotherapies are expected to play a key role in transforming cancer treatment. With substantial investments in the development pipeline, the market offers strong long-term potential, though challenges related to cost, accessibility, and efficacy remain.

Key Market Drivers

Rapid Advances in Immunotherapy Research

Rapid advances in immunotherapy research are poised to propel the growth of the Global Checkpoint Inhibitor Refractory Cancer Market. As innovative therapies emerge, addressing the challenges posed by checkpoint inhibitor refractory cancers, a surge in market demand is anticipated. Immunotherapy, with its ability to harness the body's immune system to combat cancer, is a focal point of research, offering new avenues for treatment-resistant cases. These breakthroughs instill confidence among healthcare providers and stakeholders, creating a conducive environment for market expansion. With ongoing clinical trials and evolving treatment protocols, the market is witnessing a transformative shift in the management of checkpoint inhibitor refractory cancers. In September 2024, OmRx Oncology, a newly established biopharmaceutical company backed by Scripps Research, launched with a Phase 2 clinical asset in-licensed from Gilead Sciences. The company's mission is to increase access to immunotherapy in regions where biologic checkpoint inhibitors are often too expensive or unavailable to patients. OmRx's clinical-stage asset, OX-4224, is an investigational oral immune checkpoint inhibitor targeting the PD-1/PD-L1 pathway. Originally discovered and developed by Gilead, OX-4224 will be assessed by OmRx for the treatment of non-small cell lung cancer (NSCLC). By in-licensing this Phase 2-ready asset, OmRx aims to offer an alternative treatment option that is potentially as effective as traditional antibody checkpoint inhibitors like Keytruda and Opdivo, but with the advantage of being a more affordable and accessible oral small molecule, particularly beneficial in countries where access to biologics is limited. This move reflects the broader trend of rapid advances in immunotherapy research, as companies seek innovative solutions to barriers related to the cost and accessibility of life-saving therapies. The promise of enhanced patient outcomes and improved survival rates is driving investments and collaborations within the pharmaceutical and biotechnology sectors. As regulatory approvals and commercialization strategies align with research milestones, the Global Checkpoint Inhibitor Refractory Cancer Market is set to experience substantial growth. Stakeholders should strategically position themselves to capitalize on these advancements, recognizing the potential for both medical breakthroughs and profitable business opportunities in this dynamic and evolving landscape.

Burgeoning Understanding of Tumor Microenvironment

The burgeoning understanding of the tumor microenvironment (TME) is poised to be a catalyst for driving growth in the Global Checkpoint Inhibitor Refractory Cancer Market. As researchers delve deeper into the intricacies of the TME, a nuanced comprehension of the complex interplay between cancer cells and their surrounding environment is emerging. This deeper insight enables the development of targeted therapies that address the unique challenges posed by checkpoint inhibitor refractory cancers within the TME. Innovations stemming from this enhanced understanding are paving the way for novel treatment strategies, offering a more tailored and effective approach to combat resistant cancers. Pharmaceutical companies are increasingly focusing on TME-centric drug development, with a growing pipeline of therapeutics designed to modulate the immune response in the specific context of the tumor's microenvironment. Investors and industry stakeholders are recognizing the pivotal role of TME research in reshaping the landscape of checkpoint inhibitor refractory cancer treatment. Strategic collaborations and investments in technologies that decipher the TME intricacies are becoming key drivers for market growth. This evolving paradigm underscores the imperative for businesses to align their strategies with the expanding knowledge of TME, positioning themselves to capitalize on the opportunities arising in the dynamic Global Checkpoint Inhibitor Refractory Cancer Market.

Government Initiatives and Regulatory Support

Government initiatives and regulatory support are anticipated to be pivotal drivers in propelling the growth of the Global Checkpoint Inhibitor Refractory Cancer Market. Increased recognition of the pressing need for innovative solutions in cancer treatment has prompted governments worldwide to foster an environment conducive to research and development. Robust funding programs and grants are incentivizing pharmaceutical and biotechnology companies to invest in the development of novel therapies targeting checkpoint inhibitor refractory cancers. Furthermore, regulatory bodies are actively streamlining approval processes and providing accelerated pathways for breakthrough treatments, facilitating a more efficient route to market for these specialized drugs. In November 2024, the University Hospital of Cologne and the French cancer center Gustave Roussy initiated a joint study called REDUCE-LUNG, focused on improving treatment outcomes for patients over 70 with advanced lung cancer. The three-year study will evaluate two treatment approaches: two cycles of chemo-immunotherapy followed by immunotherapy maintenance, compared to the standard treatment of four cycles of chemo-immunotherapy. The research will take place at 15 selected centers in Germany and France, with full funding provided by the German Dr. Rolf M. Schwiete Stiftung and the French Oddo family. This study highlights the role of government and regulatory support, as well as private funding, in fostering collaborative efforts that address critical healthcare challenges, particularly for aging populations with complex medical needs. The alignment of regulatory frameworks with the urgency of addressing unmet medical needs in oncology creates a supportive ecosystem for industry players. As governments and regulatory agencies prioritize the advancement of cancer therapeutics, businesses operating in the checkpoint inhibitor refractory cancer space stand to benefit from reduced development timelines and enhanced market access. The collaborative efforts between public institutions and private enterprises foster an environment where innovation flourishes, laying the foundation for sustained growth in the Global Checkpoint Inhibitor Refractory Cancer Market. Companies should strategically position themselves to leverage these supportive measures and contribute to the evolving landscape of cancer care.

Key Market Challenges

Intrinsic Tumor Heterogeneity

Intrinsic tumor heterogeneity presents a formidable obstacle that can impede the growth of the Global Checkpoint Inhibitor Refractory Cancer Market. The inherent diversity in genetic and molecular profiles within tumors of individual patients poses challenges in developing universally effective therapies. This complexity complicates the identification of specific targets for checkpoint inhibitors, hindering the creation of treatments that can comprehensively address the varied facets of tumor heterogeneity. The intricate landscape of intrinsic tumor heterogeneity not only extends the timelines and costs associated with drug development but also raises uncertainties regarding treatment outcomes. Tailoring therapies to the unique genetic makeup of each patient becomes a daunting task, demanding sophisticated diagnostic tools and personalized treatment strategies. The market's growth potential is hampered as the demand for precision medicine intensifies. Addressing intrinsic tumor heterogeneity necessitates innovative solutions such as advanced genomic profiling and artificial intelligence-driven analytics to unravel the complexities of individual tumors. Industry players must navigate these challenges strategically, investing in technologies that enable a nuanced understanding of tumor heterogeneity to ensure the development of more targeted and efficacious checkpoint inhibitor refractory cancer treatments.

Limited Biomarker Validation

Limited biomarker validation stands as a formidable hindrance to the growth of the Global Checkpoint Inhibitor Refractory Cancer Market. Biomarkers are pivotal in identifying patients who would benefit most from checkpoint inhibitor therapies, aiding in treatment selection and predicting responses. However, the insufficient validation of these biomarkers introduces uncertainties, impacting the reliability and effectiveness of treatment strategies. The absence of widely validated biomarkers impedes the development of targeted therapies and complicates the regulatory approval process. Healthcare providers face challenges in accurately identifying eligible patients, potentially leading to suboptimal treatment outcomes and increased healthcare costs. The industry's ability to deliver personalized and precision medicine is stymied, as the lack of validated biomarkers undermines the confidence of clinicians and investors alike. Addressing this bottleneck requires substantial investment in rigorous clinical validation studies and collaborative efforts between pharmaceutical companies, research institutions, and regulatory bodies. Successful biomarker validation not only enhances treatment efficacy but also fosters greater confidence in the market, ultimately driving widespread adoption of checkpoint inhibitor refractory cancer therapies and fueling the market's sustained growth.

Key Market Trends

Combination Therapies and Synergistic Approaches

The growth of the Global Checkpoint Inhibitor Refractory Cancer Market is poised to be significantly propelled by the adoption of combination therapies and synergistic approaches. Recognizing the complex nature of cancer, pharmaceutical companies are increasingly exploring the synergies between checkpoint inhibitors and complementary treatments, such as targeted therapies, immunomodulators, or traditional chemotherapy. Combination therapies offer a multi-faceted approach, addressing diverse mechanisms involved in tumor resistance and enhancing overall treatment effectiveness. Synergistic combinations not only improve response rates but also have the potential to overcome intrinsic and acquired resistance to checkpoint inhibitors. This strategic approach is reshaping the treatment landscape, providing more comprehensive solutions for patients with refractory cancers. The market's growth is driven by the accelerated development and clinical validation of these combination therapies, supported by collaborative efforts among industry stakeholders, research institutions, and regulatory bodies. Investors are increasingly attracted to the potential of these innovative treatment approaches, fostering a dynamic ecosystem that encourages further advancements. As combination therapies demonstrate improved clinical outcomes and gain regulatory approvals, they are expected to become a cornerstone in the management of checkpoint inhibitor refractory cancers, driving sustained market growth and offering new avenues for therapeutic innovation. Industry players should position themselves strategically to capitalize on these emerging opportunities in the evolving landscape of cancer treatment.

Focus on Tumor Microenvironment Modulation

The growth trajectory of the Global Checkpoint Inhibitor Refractory Cancer Market is being markedly influenced by a strategic focus on tumor microenvironment (TME) modulation. Recognizing the pivotal role of TME in influencing treatment responses, pharmaceutical and biotech companies are intensifying efforts to develop therapies that specifically target and modulate the microenvironment surrounding cancer cells. Innovations in TME modulation involve tailoring treatments to disrupt the immunosuppressive elements within the tumor, making it more susceptible to checkpoint inhibitor therapies. This approach not only enhances the efficacy of checkpoint inhibitors but also addresses the challenges posed by tumor heterogeneity and resistance. This strategic emphasis on TME modulation is attracting significant investments and fostering collaborations across the industry. As promising preclinical and clinical results emerge, regulatory bodies are increasingly recognizing the importance of these advancements, expediting the development and approval processes. The evolving landscape, driven by a keen focus on TME, is reshaping the market dynamics, offering a paradigm shift in the treatment of checkpoint inhibitor refractory cancers. Companies that position themselves at the forefront of TME modulation research are likely to drive the market's growth, providing innovative solutions that meet the urgent medical needs in this specialized therapeutic domain.

Segmental Insights

Type Insights

Based on Type, the PD-1 Inhibitor emerged as the fastest growing segment in the global market for Checkpoint Inhibitor Refractory Cancer during the forecast period. These immunotherapies play a crucial role in stimulating the body's immune response against cancer by blocking the PD-1 pathway. As a key component of checkpoint inhibitor therapy, PD-1 inhibitors have shown significant efficacy across various cancer types, making them instrumental in overcoming resistance mechanisms and addressing refractory cases. Their versatility in treating diverse tumor types broadens their market potential, prompting substantial investment from pharmaceutical companies in both monotherapy and combination therapy development. The market's growth is driven by the expanding availability of PD-1 inhibitors, supported by strong clinical results and regulatory approvals. For example, in November 2024, Dr. Reddy's Laboratories launched Toripalimab in India for treating nasopharyngeal carcinoma, making India the third country after China and the U.S. to access this next-generation PD-1 inhibitor. Clinical data shows that combining Toripalimab with standard chemotherapy reduced the risk of progression or death by 48%. As the demand for effective treatments for refractory cancers increases, PD-1 inhibitors are set to become major revenue drivers, shaping the market and driving innovation in immunotherapy. Industry players should strategically position themselves to leverage the growing potential of PD-1 inhibitors in addressing the evolving needs of cancer patients worldwide.

Application Insights

Based on Application, the Hodgkin Lymphoma emerged as the dominating segment in the global market for Checkpoint Inhibitor Refractory Cancer in 2024. The growth of the Global Checkpoint Inhibitor Refractory Cancer Market is set to be significantly driven by the unique position of Hodgkin Lymphoma (HL) within this therapeutic landscape. Hodgkin Lymphoma, characterized by the presence of Reed-Sternberg cells, has demonstrated a notable responsiveness to checkpoint inhibitors, particularly PD-1 inhibitors like pembrolizumab and nivolumab. As a flagship indication for checkpoint inhibitor success, the positive clinical outcomes in refractory or relapsed Hodgkin Lymphoma cases have underscored the potential of these immunotherapies. The remarkable efficacy in HL has led to expanded regulatory approvals and an increasing acceptance of checkpoint inhibitors as a standard treatment option. The success in HL not only establishes checkpoint inhibitors as a viable therapeutic approach but also serves as a catalyst for broader applications across various cancers. This has attracted substantial investments from pharmaceutical companies and heightened interest from clinicians, driving research and development efforts. The unique dynamics of Hodgkin Lymphoma, acting as a trailblazer in checkpoint inhibitor refractory cancers, positions it as a key driver for the overall market growth. Industry players should leverage these insights, focusing on advancements in checkpoint inhibitors for HL, to capitalize on the expanding opportunities within the evolving landscape of cancer therapeutics.

Regional Insights

Based on Region, North America emerged as the dominant region in the Global Checkpoint Inhibitor Refractory Cancer Market in 2024. The region benefits from a well-established healthcare system, broad access to advanced cancer therapies, and a robust network of leading pharmaceutical companies. Additionally, the U.S. boasts a favorable regulatory landscape, with the FDA fast-tracking approvals for breakthrough therapies, ensuring quicker access to innovative treatments. North America is also a hub for significant investments in oncology research, clinical trials, and advanced medical technologies, driving ongoing innovation in immunotherapies. According to Canadian Cancer Statistics, 43% of Canadian women and 45% of Canadian men will develop cancer in their lifetime. This high demand for effective cancer treatments, combined with strong healthcare infrastructure, insurance coverage, and widespread awareness, ensures broad access to new therapies. The region's large population and high cancer incidence rates further fuel market growth, positioning North America as the key center for the development and commercialization of checkpoint inhibitors. These factors collectively solidify North America's dominant position in the checkpoint inhibitor refractory cancer market.

Key Market Players

• Bristol-Myers Squibb Company.
• AstraZeneca plc.
• Merck KGaA
• F. Hoffmann-La Roche Ltd
• Regeneron Pharmaceuticals Inc
• Pfizer Inc
• Janssen Global Services, LLC
• 4SC AG
• Mirati Therapeutics, Inc.
• Ascentage Pharma.

Report Scope:

In this report, the Global Checkpoint Inhibitor Refractory Cancer Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Checkpoint Inhibitor Refractory Cancer Market, By Type:

• PD-1 Inhibitor
• PD-L1 Inhibitor
• Others

Checkpoint Inhibitor Refractory Cancer Market, By Application:

• Lung Cancer
• Bladder Cancer
• Melanoma
• Hodgkin Lymphoma
• Others

Checkpoint Inhibitor Refractory Cancer Market, By Region:

• North America
  • United States
  • Canada
  • Mexico
• Europe
  • France
  • United Kingdom
  • Italy
  • Germany
  • Spain
• Asia Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
• South America
  • Brazil
  • Argentina
  • Colombia
• Middle East & Africa
  • South Africa
  • Saudi Arabia
  • UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Checkpoint Inhibitor Refractory Cancer Market.

Available Customizations:

Global Checkpoint Inhibitor Refractory Cancer market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

Detailed analysis and profiling of additional market players (up to five).

Table of Contents

1. Product Overview

• 1.1. Market Definition
• 1.2. Scope of the Market
  • 1.2.1. Markets Covered
  • 1.2.2. Years Considered for Study
  • 1.2.3. Key Market Segmentations

2. Research Methodology

• 2.1. Objective of the Study
• 2.2. Baseline Methodology
• 2.3. Key Industry Partners
• 2.4. Major Association and Secondary Sources
• 2.5. Forecasting Methodology
• 2.6. Data Triangulation & Validation
• 2.7. Assumptions and Limitations

3. Executive Summary

• 3.1. Overview of the Market
• 3.2. Overview of Key Market Segmentations
• 3.3. Overview of Key Market Players
• 3.4. Overview of Key Regions/Countries
• 3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Checkpoint Inhibitor Refractory Cancer Market Outlook

• 5.1. Market Size & Forecast
  • 5.1.1. By Value
• 5.2. Market Share & Forecast
  • 5.2.1. By Type (PD-1 Inhibitor, PD-L1 Inhibitor, Others)
  • 5.2.2. By Application (Lung Cancer, Bladder Cancer, Melanoma, Hodgkin Lymphoma, Others)
  • 5.2.3. By Region (North America, Europe, Asia Pacific, South America, Middle East & Africa)
  • 5.2.4. By Company (2024)
• 5.3. Market Map
• 5.3.1 By Type
• 5.3.2 By Application
• 5.3.3 By Region

6. North America Checkpoint Inhibitor Refractory Cancer Market Outlook

• 6.1. Market Size & Forecast
  • 6.1.1. By Value
• 6.2. Market Share & Forecast
  • 6.2.1. By Type (PD-1 Inhibitor, PD-L1 Inhibitor, Others)
  • 6.2.2. By Application (Lung Cancer, Bladder Cancer, Melanoma, Hodgkin Lymphoma, Others)
  • 6.2.3. By Country
• 6.3. North America: Country Analysis
  • 6.3.1. United States Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 6.3.1.1. Market Size & Forecast
      • 6.3.1.1.1. By Value
    • 6.3.1.2. Market Share & Forecast
      • 6.3.1.2.1. By Type
      • 6.3.1.2.2. By Application
  • 6.3.2. Canada Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 6.3.2.1. Market Size & Forecast
      • 6.3.2.1.1. By Value
    • 6.3.2.2. Market Share & Forecast
      • 6.3.2.2.1. By Type
      • 6.3.2.2.2. By Application
  • 6.3.3. Mexico Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 6.3.3.1. Market Size & Forecast
      • 6.3.3.1.1. By Value
    • 6.3.3.2. Market Share & Forecast
      • 6.3.3.2.1. By Type
      • 6.3.3.2.2. By Application

7. Europe Checkpoint Inhibitor Refractory Cancer Market Outlook

• 7.1. Market Size & Forecast
  • 7.1.1. By Value
• 7.2. Market Share & Forecast
  • 7.2.1. By Type (PD-1 Inhibitor, PD-L1 Inhibitor, Others)
  • 7.2.2. By Application (Lung Cancer, Bladder Cancer, Melanoma, Hodgkin Lymphoma, Others)
  • 7.2.3. By Country
• 7.3. Europe: Country Analysis
  • 7.3.1. France Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 7.3.1.1. Market Size & Forecast
      • 7.3.1.1.1. By Value
    • 7.3.1.2. Market Share & Forecast
      • 7.3.1.2.1. By Type
      • 7.3.1.2.2. By Application
  • 7.3.2. Germany Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 7.3.2.1. Market Size & Forecast
      • 7.3.2.1.1. By Value
    • 7.3.2.2. Market Share & Forecast
      • 7.3.2.2.1. By Type
      • 7.3.2.2.2. By Application
  • 7.3.3. United Kingdom Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 7.3.3.1. Market Size & Forecast
      • 7.3.3.1.1. By Value
    • 7.3.3.2. Market Share & Forecast
      • 7.3.3.2.1. By Type
      • 7.3.3.2.2. By Application
  • 7.3.4. Italy Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 7.3.4.1. Market Size & Forecast
      • 7.3.4.1.1. By Value
    • 7.3.4.2. Market Share & Forecast
      • 7.3.4.2.1. By Type
      • 7.3.4.2.2. By Application
  • 7.3.5. Spain Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 7.3.5.1. Market Size & Forecast
      • 7.3.5.1.1. By Value
    • 7.3.5.2. Market Share & Forecast
      • 7.3.5.2.1. By Type
      • 7.3.5.2.2. By Application

8. Asia Pacific Checkpoint Inhibitor Refractory Cancer Market Outlook

• 8.1. Market Size & Forecast
  • 8.1.1. By Value
• 8.2. Market Share & Forecast
  • 8.2.1. By Type (PD-1 Inhibitor, PD-L1 Inhibitor, Others)
  • 8.2.2. By Application (Lung Cancer, Bladder Cancer, Melanoma, Hodgkin Lymphoma, Others)
  • 8.2.3. By Country
• 8.3. Asia Pacific: Country Analysis
  • 8.3.1. China Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 8.3.1.1. Market Size & Forecast
      • 8.3.1.1.1. By Value
    • 8.3.1.2. Market Share & Forecast
      • 8.3.1.2.1. By Type
      • 8.3.1.2.2. By Application
  • 8.3.2. India Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 8.3.2.1. Market Size & Forecast
      • 8.3.2.1.1. By Value
    • 8.3.2.2. Market Share & Forecast
      • 8.3.2.2.1. By Type
      • 8.3.2.2.2. By Application
  • 8.3.3. Japan Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 8.3.3.1. Market Size & Forecast
      • 8.3.3.1.1. By Value
    • 8.3.3.2. Market Share & Forecast
      • 8.3.3.2.1. By Type
      • 8.3.3.2.2. By Application
  • 8.3.4. South Korea Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 8.3.4.1. Market Size & Forecast
      • 8.3.4.1.1. By Value
    • 8.3.4.2. Market Share & Forecast
      • 8.3.4.2.1. By Type
      • 8.3.4.2.2. By Application
  • 8.3.5. Australia Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 8.3.5.1. Market Size & Forecast
      • 8.3.5.1.1. By Value
    • 8.3.5.2. Market Share & Forecast
      • 8.3.5.2.1. By Type
      • 8.3.5.2.2. By Application

9. South America Checkpoint Inhibitor Refractory Cancer Market Outlook

• 9.1. Market Size & Forecast
  • 9.1.1. By Value
• 9.2. Market Share & Forecast
  • 9.2.1. By Type (PD-1 Inhibitor, PD-L1 Inhibitor, Others)
  • 9.2.2. By Application (Lung Cancer, Bladder Cancer, Melanoma, Hodgkin Lymphoma, Others)
  • 9.2.3. By Country
• 9.3. South America: Country Analysis
  • 9.3.1. Brazil Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 9.3.1.1. Market Size & Forecast
      • 9.3.1.1.1. By Value
    • 9.3.1.2. Market Share & Forecast
      • 9.3.1.2.1. By Type
      • 9.3.1.2.2. By Application
  • 9.3.2. Argentina Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 9.3.2.1. Market Size & Forecast
      • 9.3.2.1.1. By Value
    • 9.3.2.2. Market Share & Forecast
      • 9.3.2.2.1. By Type
      • 9.3.2.2.2. By Application
  • 9.3.3. Colombia Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 9.3.3.1. Market Size & Forecast
      • 9.3.3.1.1. By Value
    • 9.3.3.2. Market Share & Forecast
      • 9.3.3.2.1. By Type
      • 9.3.3.2.2. By Application

10. Middle East and Africa Checkpoint Inhibitor Refractory Cancer Market Outlook

• 10.1. Market Size & Forecast
  • 10.1.1. By Value
• 10.2. Market Share & Forecast
  • 10.2.1. By Type (PD-1 Inhibitor, PD-L1 Inhibitor, Others)
  • 10.2.2. By Application (Lung Cancer, Bladder Cancer, Melanoma, Hodgkin Lymphoma, Others)
  • 10.2.3. By Country
• 10.3. MEA: Country Analysis
  • 10.3.1. South Africa Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 10.3.1.1. Market Size & Forecast
      • 10.3.1.1.1. By Value
    • 10.3.1.2. Market Share & Forecast
      • 10.3.1.2.1. By Type
      • 10.3.1.2.2. By Application
  • 10.3.2. Saudi Arabia Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 10.3.2.1. Market Size & Forecast
      • 10.3.2.1.1. By Value
    • 10.3.2.2. Market Share & Forecast
      • 10.3.2.2.1. By Type
      • 10.3.2.2.2. By Application
  • 10.3.3. UAE Checkpoint Inhibitor Refractory Cancer Market Outlook
    • 10.3.3.1. Market Size & Forecast
      • 10.3.3.1.1. By Value
    • 10.3.3.2. Market Share & Forecast
      • 10.3.3.2.1. By Type
      • 10.3.3.2.2. By Application

11. Market Dynamics

• 11.1. Drivers
• 11.2. Challenges

12. Market Trends & Developments

• 12.1. Recent Development
• 12.2. Mergers & Acquisitions
• 12.3. Product Launches

13. Global Checkpoint Inhibitor Refractory Cancer Market: SWOT Analysis

14. Porter's Five Forces Analysis

• 14.1. Competition in the Industry
• 14.2. Potential of New Entrants
• 14.3. Power of Suppliers
• 14.4. Power of Customers
• 14.5. Threat of Substitute Products

15. Competitive Landscape

• 15.1. Bristol-Myers Squibb Company.
  • 15.1.1. Business Overview
  • 15.1.2. Product Offerings
  • 15.1.3. Recent Developments
  • 15.1.4. Financials (As Reported)
  • 15.1.5. Key Personnel
  • 15.1.6. SWOT Analysis
• 15.2. AstraZeneca plc.
• 15.3. Merck KGaA
• 15.4. F. Hoffmann-La Roche Ltd
• 15.5. Regeneron Pharmaceuticals Inc
• 15.6. Pfizer Inc
• 15.7. Janssen Global Services, LLC
• 15.8. 4SC AG
• 15.9. Mirati Therapeutics, Inc.
• 15.10. Ascentage Pharma.

16. Strategic Recommendations

17. About Us & Disclaimer