市場調査レポート
商品コード
1485042
医薬品原薬CDMO市場- 世界の産業規模、シェア、動向、機会、予測、分子タイプ別、合成別、薬剤タイプ別、ワークフロー別、用途別、地域別、競合別、2019-2029年Active Pharmaceutical Ingredients CDMO Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Molecule Type, By Synthesis, By Drug Type, By Workflow, By Application, By Region and Competition, 2019-2029F |
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医薬品原薬CDMO市場- 世界の産業規模、シェア、動向、機会、予測、分子タイプ別、合成別、薬剤タイプ別、ワークフロー別、用途別、地域別、競合別、2019-2029年 |
出版日: 2024年05月24日
発行: TechSci Research
ページ情報: 英文 182 Pages
納期: 2~3営業日
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医薬品原薬CDMOの世界市場規模は2023年に919億8,000万米ドルとなり、予測期間では2029年までのCAGRが6.10%で着実な成長が予測されています。
医薬品業界は、原薬の製造や医薬品アプリケーションの開発において多くの課題に直面しています。これらの課題には、高品質な基準を維持しながらコストを削減する必要性、手頃な価格の設備への要求、革新的な製品を迅速に市場に投入するプレッシャーなどが含まれます。このような課題に対応するため、開発・製造受託機関(CDMO)が製薬企業の重要なパートナーとして台頭してきました。CDMOは製薬会社と協力し、インフラやリソースへの追加投資を必要とせずに医薬品の開発・製造を行います。原薬製造をCDMOにアウトソーシングすることで、製薬企業は研究やマーケティングといった自社のコアコンピタンスに集中できる一方、製造や開発においてはCDMOの専門知識や能力を活用することができます。このパートナーシップモデルにより、製薬会社は新製品をより早く、よりコスト効率よく市場に投入することができます。製薬CDMOの主な役割のひとつは、原薬のアウトソーシングです。これは、製薬会社から提供された仕様書に従って、医薬品原薬(API)や医薬品中間体を製造することです。CDMOは、専門的な設備や化学・製造の専門知識を活用し、規制基準を満たす高品質の原薬を製造します。
市場概要 | |
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予測期間 | 2025-2029 |
市場規模:2023年 | 919億8,000万米ドル |
市場規模:2029年 | 1,307億米ドル |
CAGR:2024年~2029年 | 6.10% |
急成長セグメント | オンコロジー |
最大市場 | 北米 |
医薬品CDMOは原薬の製造に加え、技術革新と開発プロセスにおいても重要な役割を果たしています。CDMOは製造前の段階で製薬企業と密接に協力し、製剤の開発、フィージビリティ・スタディの実施、プロセスの最適化を行います。この連携により、最終製品が有効性、安全性、品質の面で望ましい仕様を満たすことが保証されます。製薬企業とCDMOのパートナーシップは相互に有益です。製薬会社は、CDMOの最先端施設、専門知識、スケーラブルな製造能力を利用することで、新薬をより迅速かつ効率的に市場に投入できるというメリットがあります。一方、CDMOは製薬会社との長期的なパートナーシップにより、安定したビジネスと成長機会を得ることができます。製薬CDMOはヘルスケア産業の成長に大きく貢献しています。製薬会社が製造・開発プロセスを処理しながらイノベーションと新興国市場に集中できるようにすることで、CDMOは創薬・開発のペースを加速させる上で重要な役割を果たしています。その結果、アンメット・メディカル・ニーズに対応し、患者の転帰を改善する新しい治療法や改良された治療法のイントロダクションつながります。製薬CDMOは製薬企業にとって不可欠なパートナーとなっており、原薬製造、製剤開発、プロセス最適化など幅広いサービスを提供しています。CDMOの専門知識と能力を活用することで、製薬会社は業務を効率化し、コストを削減し、革新的な製品をより早く市場に投入することができます。製薬企業とCDMOの協力的なパートナーシップは、ヘルスケア業界の積極的な成長を促進し、世界中の患者のために新しい治療法の開発を進めるために不可欠です。
カスタマイズされた医薬品開発に対する需要の増加
バイオ医薬品分野の成長
複雑な薬物分子の増加
規制の複雑さ
品質管理とコンプライアンス
細胞治療と遺伝子治療
Global Active Pharmaceutical Ingredients CDMO Market was valued at USD 91.98 Billion in 2023 and is anticipated to project steady growth in the forecast period with a CAGR of 6.10% through 2029. The pharmaceutical industry faces numerous challenges in the manufacturing of drug substances and the development of pharmaceutical applications. These challenges include the need to reduce costs while maintaining high-quality standards, the requirement for affordable equipment, and the pressure to bring innovative products to market quickly. In response to these challenges, Contract Development and Manufacturing Organizations (CDMOs) have emerged as key partners for pharmaceutical companies. CDMOs collaborate with pharmaceutical companies to develop and manufacture drugs without the need for additional investment in infrastructure or resources. By outsourcing drug substance manufacturing to CDMOs, pharmaceutical companies can focus on their core competencies such as research and marketing, while leveraging the expertise and capabilities of CDMOs in manufacturing and development. This partnership model allows pharmaceutical companies to bring new products to market faster and more cost-effectively. One of the primary roles of Pharmaceutical CDMOs is to handle the outsourcing of drug substances. This involves the production of active pharmaceutical ingredients (APIs) or drug intermediates according to the specifications provided by the pharmaceutical companies. CDMOs utilize their specialized facilities and expertise in chemistry and manufacturing to produce high-quality drug substances that meet regulatory standards.
Market Overview | |
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Forecast Period | 2025-2029 |
Market Size 2023 | USD 91.98 Billion |
Market Size 2029 | USD 130.70 Billion |
CAGR 2024-2029 | 6.10% |
Fastest Growing Segment | Oncology |
Largest Market | North America |
In addition to manufacturing drug substances, Pharmaceutical CDMOs also play a crucial role in the innovation and development process. CDMOs work closely with pharmaceutical companies during the pre-manufacturing phase to develop formulations, conduct feasibility studies, and optimize processes. This collaboration ensures that the final product meets the desired specifications in terms of efficacy, safety, and quality. The partnership between pharmaceutical companies and CDMOs is mutually beneficial. Pharmaceutical companies benefit from access to CDMO's state-of-the-art facilities, specialized expertise, and scalable manufacturing capabilities, allowing them to bring new drugs to market faster and more efficiently. On the other hand, CDMOs benefit from long-term partnerships with pharmaceutical companies, which provide a steady stream of business and opportunities for growth. Pharmaceutical CDMOs contribute significantly to the positive growth of the healthcare industry. By enabling pharmaceutical companies to focus on innovation and marketing while handling the manufacturing and development process, CDMOs play a vital role in accelerating the pace of drug discovery and development. This, in turn, leads to the introduction of new and improved therapies that address unmet medical needs and improve patient outcomes. Pharmaceutical CDMOs have become integral partners for pharmaceutical companies, offering a range of services including drug substance manufacturing, formulation development, and process optimization. By leveraging the expertise and capabilities of CDMOs, pharmaceutical companies can streamline their operations, reduce costs, and bring innovative products to market faster. The collaborative partnership between pharmaceutical companies and CDMOs is essential for driving positive growth in the healthcare industry and advancing the development of new therapies for patients worldwide.
Key Market Drivers
Increasing Demand for Customized Drug Development
Pharmaceutical companies often require specialized expertise and technologies to develop and manufacture customized drugs, which may include complex small molecules, biologics, high-potency compounds, or novel formulations. CDMOs with a focus on customization have the necessary knowledge and infrastructure to meet these specific needs, making them invaluable partners for pharmaceutical companies. Customized drug development often involves innovative and unique approaches to drug design and manufacturing. CDMOs can provide pharmaceutical companies with the resources and capabilities to expedite drug development processes, reducing time-to-market for new drugs.
Customized drug development can be resource-intensive, requiring substantial investments in research and development (R&D). Outsourcing to CDMOs allows pharmaceutical companies to access specialized capabilities without the need for substantial in-house investments, thereby reducing overall R&D costs. CDMOs offer scalable manufacturing solutions, allowing pharmaceutical companies to adjust production volumes as needed. This scalability is crucial for customized drugs, as demand can vary widely, from small-batch clinical trials to large-scale commercial production. Customized drug development often involves high levels of technical risk due to the unique nature of the compounds or formulations. By partnering with experienced CDMOs, pharmaceutical companies can mitigate these risks by leveraging the CDMO's expertise and track record in handling similar challenges. CDMOs specializing in customized drug development are well-versed in navigating complex regulatory requirements. They can help ensure that the customized drugs meet all regulatory standards, which is crucial for gaining approval and commercialization.
Growing Biopharmaceuticals Sector
Biopharmaceuticals, which include biologics like monoclonal antibodies, vaccines, and gene therapies, require specialized manufacturing processes. CDMOs with expertise in bioprocessing and biomanufacturing are in high demand to assist pharmaceutical companies in producing these complex and large-molecule drugs. Many pharmaceutical companies, especially smaller or newer entrants in the industry, may not have the in-house expertise or infrastructure for biologics development and manufacturing. They turn to CDMOs to access the necessary resources and skills. Building and maintaining biopharmaceutical manufacturing facilities can be incredibly expensive and time-consuming. Outsourcing to CDMOs allows pharmaceutical companies to reduce capital expenditures, minimize operational costs, and achieve cost-efficiency in biologics production.
The biopharmaceutical industry often faces fluctuations in demand, particularly for biologics with variable production requirements. CDMOs offer the flexibility to scale up or down production volumes as needed, optimizing resource utilization for pharmaceutical companies. Regulatory agencies have stringent requirements for the manufacturing and quality control of biologics. Established CDMOs have a track record of compliance with these regulations, giving pharmaceutical companies confidence in the quality and safety of their biopharmaceutical products. CDMOs specializing in biologics can expedite the drug development and manufacturing process. Their expertise, infrastructure, and streamlined operations can significantly reduce the time it takes to bring biopharmaceutical products to market, enabling pharmaceutical companies to capture opportunities more quickly.
Rise in Complex Drug Molecules
Complex drug molecules, which include high-potency APIs, biologics, and advanced formulations, require specialized knowledge and capabilities for their development and manufacturing. CDMOs with expertise in handling complex drug molecules become essential partners for pharmaceutical companies seeking to navigate the challenges of these compounds. Complex drug molecules often necessitate the use of advanced technologies and sophisticated manufacturing processes. CDMOs invest in state-of-the-art equipment and infrastructure to accommodate these requirements, making them well-suited to support the development and production of complex drugs. Developing and manufacturing complex drug molecules can be associated with higher technical and regulatory risks. Pharmaceutical companies can mitigate these risks by partnering with experienced CDMOs that have a proven track record of successfully handling complex compounds.
Complex drug molecules frequently face rigorous regulatory scrutiny due to their unique characteristics. CDMOs specializing in complex compounds have established quality assurance systems and compliance protocols to ensure that the products meet regulatory requirements. Developing and maintaining the infrastructure for complex drug manufacturing can be prohibitively expensive. By outsourcing to CDMOs, pharmaceutical companies can reduce capital investments, minimize operational costs, and achieve cost-efficiency in the production of complex drug molecules. CDMOs can tailor their services to the specific needs of pharmaceutical companies developing complex drugs. This customization ensures that the manufacturing processes are optimized for the unique properties and requirements of each compound.
Key Market Challenges
Regulatory Complexities
The pharmaceutical industry is highly regulated, and CDMOs must adhere to a myriad of stringent quality and safety standards. Compliance with these regulations often requires significant investments in infrastructure, personnel, and documentation. The associated compliance costs can reduce profit margins and make it challenging for CDMOs to offer competitive pricing. Regulatory approvals and compliance checks can introduce delays into the drug development and manufacturing process. CDMOs may face prolonged approval processes, inspections, and audits, which can impact project timelines. Pharmaceutical companies may seek faster alternatives, such as in-house manufacturing, to mitigate these delays. Meeting regulatory requirements demands substantial resources, including specialized personnel and extensive documentation. Smaller or newer CDMOs may struggle to allocate the necessary resources, hindering their ability to compete effectively in the market.
The pharmaceutical regulatory landscape varies from one region to another, with differences in standards, documentation, and inspection requirements. CDMOs operating in multiple countries must navigate this complex global regulatory environment, which can be both time-consuming and costly. Regulatory non-compliance can have severe consequences, including product recalls, legal penalties, and damage to a CDMO's reputation. The fear of non-compliance may deter pharmaceutical companies from partnering with CDMOs, especially those without a strong track record of regulatory adherence. Regulatory agencies demand extensive documentation of manufacturing processes, quality control, and product testing. Maintaining accurate and comprehensive records is resource-intensive and can divert CDMO staff from core activities.
Quality Control and Compliance
Ensuring quality and compliance requires significant investments in infrastructure, personnel, and quality control processes. CDMOs must allocate substantial resources to maintain compliance, which can increase operational costs and reduce profit margins. Quality assurance and compliance procedures often involve meticulous documentation, quality control checks, and validation processes. These activities can be time-consuming and may introduce delays into project timelines, potentially frustrating pharmaceutical clients. Regulatory authorities impose strict standards on the pharmaceutical industry to ensure product safety and efficacy. CDMOs must continuously monitor and adapt to these evolving regulations, which can be complex and demanding.
Non-compliance with quality and regulatory standards can have severe consequences, including product recalls, regulatory fines, and reputational damage. The fear of non-compliance can make pharmaceutical companies cautious about partnering with CDMOs that do not have a strong track record in this regard. Maintaining comprehensive documentation for every aspect of drug development and manufacturing is a fundamental requirement for compliance. The extensive paperwork and record-keeping can be resource-intensive and divert CDMO staff from core tasks. The global pharmaceutical market encompasses a range of regulatory bodies, each with its own set of requirements. CDMOs operating on a global scale must navigate the varying compliance standards of different regions, adding complexity to their operations.
Key Market Trends
Cell and Gene Therapies
Cell and gene therapies require highly specialized expertise and infrastructure for development and manufacturing. CDMOs with capabilities in cell culture, viral vector production, and gene editing technologies are in high demand to support these innovative therapies. CDMOs are investing heavily in cutting-edge technologies and facilities tailored for cell and gene therapy production. This includes state-of-the-art cleanroom environments, bioreactors, and cryopreservation systems designed to meet the unique requirements of these therapies. The growth in demand for cell and gene therapies has prompted CDMOs to expand their manufacturing capacity in this sector. This includes constructing dedicated facilities to handle the specialized processes involved in the production of these therapies.
The regulatory landscape for cell and gene therapies is complex and evolving. CDMOs specializing in these therapies possess in-depth knowledge of regulatory requirements, helping pharmaceutical companies navigate the approval process and ensure compliance. Cell and gene therapies come with inherent technical and regulatory risks. Pharmaceutical companies mitigate these risks by partnering with CDMOs experienced in managing the complexities and challenges associated with these therapies. The demand for cell and gene therapies extends worldwide, necessitating a global presence for CDMOs to provide access to diverse markets and ensure compliance with local regulatory authorities.
Segmental Insights
Synthesis Insights
Based on Synthesis, the biotech emerged as the fastest growing segment in the Global Active Pharmaceutical Ingredients CDMO Market in 2023. The biotech sector is increasingly focused on rare diseases, leading to a growing demand for CDMOs specializing in the development and manufacturing of orphan drugs. These drugs often require unique formulations and production processes. As research in neurodegenerative disorders like Alzheimer's and Parkinson's disease advances, CDMOs are providing support for the development of innovative therapies targeting these conditions. This segment is poised for growth as more therapies progress through clinical trials. The development of vaccines, antiviral drugs, and treatments for infectious diseases remains a critical area of biotech research. CDMOs are contributing to the manufacturing of vaccines and therapies for infectious diseases, particularly in response to global health crises like pandemics.
Drug Type Insights
Based on Drug Type, the generics emerged as the dominating segment in the Global Active Pharmaceutical Ingredients CDMO Market during forecast period. Generic drugs are typically produced at a lower cost compared to their branded counterparts. CDMOs specializing in generics can leverage efficient and cost-effective manufacturing processes to meet the high demand for these products. The rising demand for generic drugs, driven by the need for affordable healthcare solutions, presents growth opportunities for CDMOs. As pharmaceutical companies seek to expand their generic drug portfolios, they often turn to CDMOs to access cost-efficient manufacturing capabilities. Generic drugs encompass a wide range of therapeutic categories, including cardiovascular, central nervous system, and respiratory medications. This diversity offers CDMOs opportunities to work on a variety of drug formulations and compounds.
Some generic drugs, particularly complex generics such as biosimilars and specialty generics, require advanced manufacturing technologies and expertise. CDMOs with capabilities in bioprocessing, sterile manufacturing, and complex dosage forms are in demand to support the development and production of these products. Ensuring regulatory compliance is crucial in the generic drug industry. CDMOs with a strong track record of meeting regulatory standards and navigating the complexities of abbreviated new drug applications (ANDAs) are sought after by pharmaceutical companies. The global reach of generic drugs creates opportunities for CDMOs with a presence in multiple regions. These CDMOs can help pharmaceutical companies access diverse markets and meet local regulatory requirements.
Regional Insights
Based on region, North America dominated the Global Active Pharmaceutical Ingredients CDMO Market in 2023. This is primarily due to North America, particularly the United States, represents one of the largest pharmaceutical markets in the world. The region's prominence in pharmaceutical research, development, and manufacturing makes it a primary driver of global API CDMO market growth. Pharmaceutical companies in North America increasingly rely on CDMOs to outsource various stages of drug development and manufacturing. The growing demand for CDMO services is driven by factors such as cost-efficiency, regulatory expertise, and access to specialized technologies. North America is a global hub for biotechnology and pharmaceutical research and innovation. This concentration of biotech and pharma companies creates a thriving ecosystem for CDMOs to collaborate and provide essential support in developing novel drug compounds.
North America is a leader in the development of biologics and complex molecules, including monoclonal antibodies, gene therapies, and biosimilars. CDMOs with expertise in these areas are well-positioned to serve the region's biopharmaceutical companies. North America has stringent regulatory requirements for drug development and manufacturing. CDMOs operating in the region must maintain a deep understanding of regulatory standards and demonstrate compliance, making them valuable partners for pharmaceutical companies navigating this complex landscape. North American pharmaceutical companies often form strategic alliances with CDMOs to expedite drug development and access specialized expertise. These collaborations drive growth in the Active Pharmaceutical Ingredients CDMO market as they tap into the region's extensive pharmaceutical infrastructure.
Cambrex Corporation
Thermo Fisher Scientific, Inc.
Recipharm AB
Corden Pharma International GmbH
Samsung Biologics Co., Ltd.
Lonza Group Ltd.
Siegfried Holding AG
Piramal Pharma Limited
AbbVie Inc.
Catalent, Inc.
In this report, the Global Active Pharmaceutical Ingredients CDMO Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:
United States
Canada
Mexico
France
United Kingdom
Italy
Germany
Spain
China
India
Japan
Australia
South Korea
Brazil
Argentina
Colombia
South Africa
Saudi Arabia
UAE
Company Profiles: Detailed analysis of the major companies present in the Global Active Pharmaceutical Ingredients CDMO Market.
Global Active Pharmaceutical Ingredients CDMO Market report with the given market data, Tech Sci Research offers customizations according to a company's specific needs. The following customization options are available for the report:
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