軟骨修復の市場規模、シェア、成長分析、治療モダリティ別、用途別、用途サイト別、地域別 - 産業予測、2024年～2031年

軟骨修復の世界市場規模は2022年に約10億米ドルと評価され、2023年の12億5,000万米ドルから2031年には43億8,000万米ドルに達すると予測され、予測期間（2024-2031年）のCAGRは17%です。

世界の軟骨修復市場は、筋骨格系疾患の有病率の上昇、関節の健康に対する意識の高まり、再生医療の進歩により大幅な成長を遂げています。軟骨の損傷は、外傷、使い過ぎ、変形性関節症のような退行性疾患によって引き起こされることが多く、効果的な修復ソリューションに対する需要が高まっています。軟骨損傷になりやすい高齢者人口の拡大や、あらゆる年齢層におけるスポーツ関連の傷害の増加が、市場をさらに活性化しています。自家軟骨細胞移植（ACI）、マイクロフラクチャー、骨軟骨自家移植、合成足場の開発など、いくつかの革新的な技術が軟骨修復の実行可能な選択肢として浮上しています。この市場の主なプレーヤーは、より侵襲性が低く、耐久性のある治療を開発するため、研究開発に継続的に投資しています。さらに、ヘルスケアプロバイダーは回復時間を短縮し、患者の予後を向上させる低侵襲手術に注力しています。政府やヘルスケア機関は、償還政策や研究イニシアティブへの資金提供を通じて再生療法の採用を促進しています。大きな成長の可能性があるにもかかわらず、市場は高い治療費、厳しい規制当局の承認、手技の複雑さといった課題に直面しています。傷害の再発率が高く、熟練した専門家の数が限られていることも、市場をさらに制約しています。しかし、3Dバイオプリンティングや幹細胞治療などの技術的進歩や個別化医療の人気の高まりにより、軟骨修復市場は今後数年で力強い成長を遂げるものと思われます。

目次

イントロダクション

• 調査の目的
• 定義
• 市場範囲

調査手法

• 情報調達
• 二次データソースと一次データソース
• 市場規模予測
• 市場の想定と制限

エグゼクティブサマリー

• 市場概要見通し
• 供給需要動向分析
• セグメント別機会分析

市場力学と見通し

• 市場力学
  • 促進要因
  • 機会
  • 抑制要因
  • 課題
• ポーターの分析

主な市場の考察

• 主な成功要因
• 競合の程度
• 主な投資機会
• 市場のエコシステム
• サプライチェーン分析
• 規制情勢
• 特許分析
• 技術分析

軟骨修復市場：治療モダリティ別

• 市場概要
• 細胞ベースの軟骨修復/軟骨再生
  • 軟骨細胞移植
  • 成長因子
  • 幹細胞
• 非細胞性軟骨修復・軟骨再生
  • 組織スキャフォールド
  • 無細胞複合材料

軟骨修復市場：用途部位別

• 市場概要
• 膝
• 股関節
• 足首と足
• その他の用途部位

軟骨修復市場：用途別

• 市場概要
• 硝子軟骨
• 線維軟骨

軟骨修復市場規模：地域別

• 市場概要
• 北米
  • 米国
  • カナダ
• 欧州
  • ドイツ
  • スペイン
  • フランス
  • 英国
  • イタリア
  • その他欧州地域
• アジア太平洋地域
  • 中国
  • インド
  • 日本
  • 韓国
  • その他アジア太平洋地域
• ラテンアメリカ
  • ブラジル
  • その他ラテンアメリカ地域
• 中東・アフリカ（MEA）
  • GCC諸国
  • 南アフリカ
  • その他中東・アフリカ地域

競合情勢

• 上位5社の比較
• 主要企業の市場ポジショニング（2023年）
• 主な市場企業が採用した戦略
• 市場における最近の活動
• 主要企業の市場シェア（2023年）

主要企業プロファイル

• DePuy Synthes（Johnson & Johnson）
• Zimmer Biomet Holdings Inc.
• Smith & Nephew plc
• Vericel Corporation
• Osiris Therapeutics Inc.
• Histogenics Corporation
• Anika Therapeutics Inc.
• Arthrex Inc.
• B. Braun Melsungen AG
• Stryker Corporation
• CONMED Corporation
• Orthocell Limited
• RTI Surgical Holdings Inc.
• MEDIPOST Co. Ltd.
• CellGenix GmbH
• Tissue Regenix Group plc
• CollPlant Biotechnologies Ltd.
• ISTO Technologies Inc.
• MTF Biologics
• CartiHeal Ltd.

Global Cartilage Repair Market size was valued at around 1 billion in 2022 and is expected to rise from USD 1.25 billion in 2023 to reach a value of USD 4.38 billion by 2031, at a CAGR of 17% over the forecast period (2024-2031).

The global cartilage repair market has experienced substantial growth due to the rising prevalence of musculoskeletal diseases, increasing awareness about joint health, and advancements in regenerative medicine. Cartilage damage, often caused by trauma, overuse, or degenerative conditions like osteoarthritis, has led to a growing demand for effective repair solutions. The market is further fueled by the expanding elderly population, which is more prone to cartilage injuries, and the rise in sports-related injuries across all age groups. Several innovative techniques, such as autologous chondrocyte implantation (ACI), microfracture, osteochondral autografts, and the development of synthetic scaffolds, have emerged as viable options for cartilage restoration. Key players in this market are continuously investing in research and development to create less invasive and more durable treatments. Additionally, healthcare providers are focusing on minimally invasive surgeries that reduce recovery time and enhance patient outcomes. Governments and healthcare organizations are promoting the adoption of regenerative therapies through reimbursement policies and funding for research initiatives. Despite the significant growth potential, the market faces challenges such as high treatment costs, stringent regulatory approvals, and the complexity of cartilage repair procedures. The high recurrence rate of injuries and the limited availability of skilled professionals further constrain the market. However, with technological advancements, such as 3D bioprinting and stem cell therapy, and the increasing popularity of personalized medicine, the cartilage repair market is poised for robust growth in the coming years.

Top-down and bottom-up approaches were used to estimate and validate the size of the Global Cartilage Repair Market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Global Cartilage Repair Market Segmental Analysis

Global Cartilage Repair Market is segmented by Treatment Modality, Application, Application Site, and region. Based on Treatment Modality, the market is segmented into Cell-based (Chondrocyte Transplantation, Stem Cells, Growth Factors), Non-cell-based (Tissue Scaffolds, Cell-free Composites). Based on Application, the market is segmented into Knee, Hip, Ankle and Foot, and Other Application Sites. Based on Application Site, the market is segmented into Hyaline Cartilage, Fibrocartilage. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & and Africa.

Drivers of the Global Cartilage Repair Market

One of the key drivers propelling the global cartilage repair market is the rapid advancement in regenerative medicine, particularly in cell-based therapies and tissue engineering. Innovations such as autologous chondrocyte implantation (ACI), stem cell therapies, and gene editing have significantly improved the efficacy of cartilage repair treatments. These technologies focus on regenerating cartilage tissue by using the body's own cells or bioengineered tissues, reducing the chances of rejection and improving long-term outcomes. Furthermore, the development of biomaterials and scaffolds that mimic the natural cartilage environment has enhanced the ability to restore joint function and prevent further damage. With the integration of 3D bioprinting and tissue scaffolding, researchers are now able to precisely reconstruct cartilage structures, paving the way for more personalized and effective treatments. The increasing collaboration between biotechnology firms, research institutes, and healthcare providers has also accelerated clinical trials, resulting in faster commercialization of advanced cartilage repair therapies.

Restraints in the Global Cartilage Repair Market

Despite the advancements in cartilage repair, the high cost of procedures remains a significant restraint for the market. Treatments such as autologous chondrocyte implantation (ACI) and stem cell therapies involve complex processes, including the extraction, cultivation, and implantation of cells, which drive up the overall costs. Additionally, the need for specialized equipment, skilled surgeons, and postoperative care contributes to the high expenses associated with these treatments. For instance, ACI, one of the most effective cartilage repair methods, can cost tens of thousands of dollars, making it inaccessible to many patients, especially in low- and middle-income regions. Moreover, in several countries, these procedures are not fully covered by insurance, placing a significant financial burden on patients. This cost factor not only limits the market penetration of advanced cartilage repair treatments but also encourages patients to opt for less effective, conservative treatment options like pain management and physical therapy.

Market Trends of the Global Cartilage Repair Market

A notable trend in the global cartilage repair market is the growing demand for minimally invasive techniques. Patients and healthcare providers are increasingly favoring procedures that involve smaller incisions, less tissue damage, and shorter recovery periods. Minimally invasive surgeries, such as arthroscopic microfracture and osteochondral autograft transfer, are gaining traction due to their ability to repair cartilage while minimizing the risks associated with traditional open surgeries. These procedures not only lead to quicker rehabilitation but also reduce the likelihood of complications such as infection or blood loss. Furthermore, technological advancements, including the use of robotics and image-guided systems, have improved the precision and success rates of these surgeries. As patient preferences shift toward less invasive options, medical device manufacturers are developing new tools and instruments to facilitate these procedures. This trend is expected to drive further innovations in cartilage repair, leading to improved patient outcomes and expanding the market in the coming years.

Table of Contents

Introduction

• Objectives of the Study
• Definitions
• Market Scope

Research Methodology

• Information Procurement
• Secondary & Primary Data Sources
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Market Overview Outlook
• Supply Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Dynamics
  • Drivers
  • Opportunities
  • Restraints
  • Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of Substitute Products
  • Bargaining Power of Buyers
  • Threat of New Entrants
  • Bargaining Power of Suppliers

Key Market Insights

• Key Success Factor
• Degree of Competition
• Top Investment Pockets
• Ecosystem of the Market
• Supply Chain Analysis
• Regulatory Landscape
• Patent Analysis
• Technology Analysis

Cartilage Repair Market, By Treatment Modality

• Market Overview
• Cell-Based Cartilage Repair/Cartilage Regeneration
  • Chondrocyte Transplantation
  • Growth Factors
  • Stem Cells
• Non-Cell-Based Cartilage Repair/Cartilage Regeneration
  • Tissue Scaffolds
  • Cell-Free Composites

Cartilage Repair Market, By Application Site

• Market Overview
• Knee
• Hip
• Ankle & Foot
• Other Application Sites

Cartilage Repair Market, By Application

• Market Overview
• Hyaline Cartilage
• Fibrocartilage

Cartilage Repair Market Size by Region

• Market Overview
• North America
  • USA
  • Canada
• Europe
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America
  • Brazil
  • Rest of Latin America
• Middle East & Africa (MEA)
  • GCC Countries
  • South Africa
  • Rest of MEA

Competitive Landscape

• Top 5 Player Comparison
• Market Positioning of Key Players, 2023
• Strategies Adopted by Key Market Players
• Recent Activities in the Market
• Key Companies Market Share (%), 2023

Key Company Profiles

• DePuy Synthes (Johnson & Johnson)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Zimmer Biomet Holdings Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Smith & Nephew plc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Vericel Corporation
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Osiris Therapeutics Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Histogenics Corporation
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Anika Therapeutics Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Arthrex Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• B. Braun Melsungen AG
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Stryker Corporation
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• CONMED Corporation
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Orthocell Limited
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• RTI Surgical Holdings Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• MEDIPOST Co. Ltd.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• CellGenix GmbH
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Tissue Regenix Group plc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• CollPlant Biotechnologies Ltd.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• ISTO Technologies Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• MTF Biologics
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• CartiHeal Ltd.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments