3D細胞培養の市場規模、シェア、成長分析、製品別、用途別、エンドユーザー別、地域別- 産業予測、2024年～2031年

3D細胞培養の市場規模は2022年に13億米ドルと評価され、2023年の15億4,000万米ドルから2031年には58億5,000万米ドルに成長し、予測期間中（2024～2031年）のCAGRは18.2％で成長する見通しです。

3Dシステムエレクトロニクスは、その進歩により従来の技術を凌駕し、医薬品研究、前臨床試験、組織工学、基礎科学の基礎となっています。細胞を3次元的に増殖させ相互作用させることで、3D細胞培養は細胞外マトリックスとの関わりを可能にし、平坦な2D培養に比べて生理学的関連性を高める。この多様性には、スフェロイド、オルガノイド、バイオプリント細胞モデル、臓器オンチップなど様々なモデルがあり、それぞれにユニークな利点があります。スフェロイドは遺伝子組成を維持したまま球形を呈し、幹細胞から作られたオルガノイドは成熟した機能を示し、オルガン・オンチップはダイナミックな流体の流れを伴う臓器構造を模倣します。慢性疾患の増加やドナー不足を背景に、臓器移植に代わる代替医療への切迫したニーズが再生医療や組織工学への関心を高めており、3D細胞培養システムは移植や薬物反応解析のためのオルガノイド培養や組織構築物の開発に優れています。このようなシステムの市場は、3D BioFibR社が2023年6月にコラーゲン繊維製品であるCollaFibR 3DスキャフォールドとμCollaFibRを発売し、3D細胞培養の機能を強化したことに代表されるように、革新的な製品のイントロダクションよって成長を目の当たりにしています。さらに、2023年12月のチャールズ・リバー・ラボラトリーズとCELLphenomics社との提携のように、がん治療における薬物スクリーニングのための3D in vitroサービスの拡大を目的とした提携は、市場の拡大を推進する需要の高まりと協力的な取り組みを反映しています。

目次

イントロダクション

• 調査の目的
• 定義
• 市場範囲

調査手法

• 情報調達
• 二次データソースと一次データソース
• 市場規模予測
• 市場の想定と制限

エグゼクティブサマリー

• 市場概要見通し
• 供給需要動向分析
• セグメント別機会分析

市場力学と見通し

• 市場力学
  • 促進要因
  • 機会
  • 抑制要因
  • 課題
• ポーターの分析

主な市場の考察

• 技術分析
• 価格分析
• 特許分析
• 技術分析
• 顧客と購買基準の分析
• 市場のエコシステム
• 規制情勢
• イノベーションマトリクス
• 主な投資の分析
• 主な成功要因
• 競合の程度

3D細胞培養市場：技術別

• 市場概要
• スキャフォールドベースの3D細胞培養
  • ハイドロゲル
  • 天然および合成ハイドロゲル
  • 固体足場
  • マイクロパターン表面
  • その他
• スキャフォールドフリーの3D細胞培養
  • ローアタッチメントプレート
  • ハンギングドロッププレート
  • 3Dバイオリアクター
  • 3Dペトリ皿
  • その他
• 磁気およびバイオプリントによる3D細胞培養
• マイクロ流体チップ上の臓器モデル

3D細胞培養市場：用途別

• 市場概要
• がん研究
• 幹細胞研究
• 創薬と毒性試験
• 組織工学と再生医療

3D細胞培養市場：最終用途別

• 市場概要
• バイオテクノロジー・製薬企業
• 受託研究ラボ
• 化粧品産業
• 学術・研究機関
• その他

3D細胞培養市場：地域別規模

• 市場概要
• 北米
  • 米国
  • カナダ
• 欧州
  • ドイツ
  • スペイン
  • フランス
  • 英国
  • イタリア
  • その他欧州地域
• アジア太平洋地域
  • 中国
  • インド
  • 日本
  • 韓国
  • その他アジア太平洋地域
• ラテンアメリカ
  • ブラジル
  • その他ラテンアメリカ地域
• 中東・アフリカ（MEA）
  • GCC諸国
  • 南アフリカ
  • その他中東・アフリカ地域

競合情勢

• 上位5社の比較
• 主要企業の市場ポジショニング（2023年）
• 主な市場企業が採用した戦略
• 市場における最近の活動
• 主要企業の市場シェア（2023年）

主要企業プロファイル

• Thermo Fisher Scientific US
• Merck KGaA
• Corning Incorporated
• Becton, Dickinson And Company
• Lonza
• 3d Biotek LLC
• Advanced Biomatrix, Inc
• Avantor, Inc
• Merck & Co., Inc.
• Tecan Trading AG
• Reprocell Inc
• Emulate
• Synthecon Incorporated
• Insphero AG
• Kirkstall Ltd.
• Promocell GmBh
• UPM Biomedicals
• CN Bio Innovations Ltd
• Synvivo Inc.
• Amsbio

3D Cell Culture Market size was valued at USD 1.3 billion in 2022 and is poised to grow from USD 1.54 billion in 2023 to USD 5.85 billion by 2031, growing at a CAGR of 18.2% during the forecast period (2024-2031).

3D system electronics have become fundamental in drug research, preclinical testing, tissue engineering, and basic sciences, surpassing traditional technologies due to their advancements. By allowing cells to grow and interact in three dimensions, 3D cell cultures enable engagement with the extracellular matrix, enhancing physiological relevance compared to flat 2D cultures. This diversity encompasses various models like spheroids, organoids, bioprinted cell models, and organs-on-chips, each offering unique benefits. Spheroids exhibit spherical shape while maintaining genetic composition, organoids from stem cells exhibit mature function, and organs-on-chips mimic organ structures with dynamic fluid flow. The pressing need for alternatives to organ transplantation, driven by escalating chronic diseases and donor shortages, has spurred interest in regenerative medicine and tissue engineering, where 3D cell culture systems excel in organoid culture and tissue construct development for transplantation and drug response analysis. The market for such systems is witnessing growth with the introduction of innovative products, exemplified by 3D BioFibR's launch of collagen fiber products, CollaFibR 3D scaffold and μCollaFibR, in June 2023, enhancing 3D cell culture capabilities. Additionally, partnerships like that between Charles River Laboratories and CELLphenomics in December 2023, aimed at expanding 3D in vitro services for drug screening in cancer therapy, reflect the increasing demand and collaborative efforts driving market expansion.

Top-down and bottom-up approaches were used to estimate and validate the size of the 3D Cell Culture market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

3D Cell Culture Market Segmental Analysis

3D Cell Culture Market is segmented by Product, Application, End User and region. Based on Product, the market can be segmented into Scaffold-based, Scaffold-free, Bioreactors, and others. Based on Application, the market is segmented into Cancer Research, Stem Cell Research & Tissue Engineering, and Others. Based on End User, the market is segmented into Biotechnology and Pharmaceutical Companies, Academic & Research Institutes, and Others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Drivers of the 3D Cell Culture Market

The burgeoning influence of 3D cell culture on advancing regenerative medicine is poised to revolutionize the field, offering a groundbreaking approach that fosters the development of intricate tissue structures mirroring natural environments. This pioneering method enables in-depth exploration of tissue regeneration and engineering, propelling it to the forefront of medical research. As regenerative medicine gains traction as a new paradigm in healthcare, demand for these sophisticated cell culture technologies, such as bio-3D, continues to surge. Consequently, this emerging technology drives growth in the 3D cell culture industry by providing highly specialized tools for researchers and clinicians to comprehend and implement regenerative therapies effectively.

Restraints in the 3D Cell Culture Market

The adoption of 3D cell cultures marks a significant advancement over traditional monolayer cultures, demanding the use of advanced cell culture resources, consequently driving up direct expenses associated with experiments. While offering numerous advantages, the implementation of 3D cell cultures results in higher costs due to the elevated prices of 3D scaffolds and materials compared to those utilized in 2D cell cultures. Especially in drug discovery efforts, where numerous experiments are crucial, employing 3D cell culture methods can inflate drug development expenses substantially, potentially making certain avenues financially unfeasible.

Market Trends of the 3D Cell Culture Market

Cutting-edge advancements in cell culture technologies have led to the rapid evolution of organ-on-a-chip and microfluidic systems, providing increasingly intricate 3D cell culture environments. These innovative platforms empower researchers to mimic inter-organ and tissue interactions with heightened accuracy. For instance, in December 2022, Emulate, Inc., launched the Emulate Chip-A1(TM) Accessible Chip through an early access program. This latest iteration expands upon the capabilities of the original Chip-S1, faithfully reproducing tissue-vascular interfaces with relevant biomechanical stimuli such as stretch and flow. The Chip-A1(TM) allows users to cultivate thicker tissues within the epithelial culture chamber and employ a broader range of drug treatment techniques, including topical or aerosolized applications, thereby augmenting versatility and experimentation capabilities.

Table of Contents

Introduction

• Objectives of the Study
• Definitions
• Market Scope

Research Methodology

• Information Procurement
• Secondary & Primary Data Sources
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Market Overview Outlook
• Supply Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Dynamics
  • Drivers
  • Opportunities
  • Restraints
  • Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of Substitute Products
  • Bargaining Power of Buyers
  • Threat of New Entrants
  • Bargaining Power of Suppliers

Key Market Insights

• Technology Analysis
• Pricing Analysis
• Patent Analysis
• Technology Analysis
• Customer & Buying Criteria Analysis
• Ecosystem of the Market
• Regulatory Landscape
• Innovation Matrix
• Top Investment Analysis
• Key Success Factor
• Degree of Competition

3D Cell Culture Market by Technology

• Market Overview
• Scaffold-based 3D Cell Cultures
  • Hydrogels
  • Natural & Synthetic Hydrogels
  • Solid Scaffolds
  • Micropatterned Surfaces
  • Others
• Scaffold-free 3D Cell Cultures
  • Low Attachment Plates
  • Hanging Drop Plates
  • 3d Bioreactors
  • 3d Petri Dishes
  • Others
• Magnetic & Bioprinted 3d Cell Cultures
• Microfluidic Organ-on-a-Chip Models

3D Cell Culture Market by Application

• Market Overview
• Cancer Research
• Stem Cell Research
• Drug Discovery & Toxicology Testing
• Tissue Engineering & Regenerative Medicine

3D Cell Culture Market by End Use

• Market Overview
• Biotechnology and Pharmaceutical Companies
• Contract Research Laboratories
• Cosmetic Industry
• Academic & Research Institutes
• Others

3D Cell Culture Market Size by Region

• Market Overview
• North America
  • USA
  • Canada
• Europe
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America
  • Brazil
  • Rest of Latin America
• Middle East & Africa (MEA)
  • GCC Countries
  • South Africa
  • Rest of MEA

Competitive Landscape

• Top 5 Player Comparison
• Market Positioning of Key Players, 2023
• Strategies Adopted by Key Market Players
• Recent Activities in the Market
• Key Companies Market Share (%), 2023

Key Company Profiles

• Thermo Fisher Scientific US
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Corning Incorporated
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Becton, Dickinson And Company
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Lonza
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• 3d Biotek LLC
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Advanced Biomatrix, Inc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Avantor, Inc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck & Co., Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Tecan Trading AG
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Reprocell Inc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Emulate
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Synthecon Incorporated
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Insphero AG
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Kirkstall Ltd.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Promocell GmBh
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• UPM Biomedicals
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• CN Bio Innovations Ltd
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Synvivo Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Amsbio
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments