リガーゼ酵素の世界市場：市場規模とシェア分析 - 動向、促進要因、競合情勢、予測（2025年～2032年）

世界のリガーゼ酵素の市場規模は、6.6％のCAGRで拡大し、2024年の4億4,210万米ドルから2032年には7億2,740万米ドルに成長すると予測されています。この成長の原動力は、遺伝子異常や感染症の診断の重要性の高まりと、世界のがん罹患率の上昇です。リガーゼ酵素は、精密医療や個別化治療のアプローチが急速に進展している分子診断、遺伝子編集、バイオ医薬品生産など、さまざまな用途で不可欠です。

クイックリガーゼは、DNA断片の迅速なライゲーションを可能にすることで、分子クローニングや遺伝子工学アプリケーションの効率を高めます。T4 DNAリガーゼは、クローニングや塩基配列決定におけるDNA断片の結合に広く使用されており、大腸菌DNAリガーゼはDNA修復や複製研究に不可欠です。Tth DNAリガーゼは、特定のDNA配列を検出するためのリガーゼ連鎖反応技術に用いられます。T4 RNAリガーゼはRNA研究で一本鎖RNAの結紮に用いられ、Pfu DNAリガーゼは遺伝子解析のための高忠実度DNA増幅やクローニングに応用されています。

古細菌由来の酵素は過酷な条件下でも安定であることが知られており、工業的応用に有益です。大腸菌は、生産が容易で研究や診断に広く応用できることから、リガーゼの一般的な供給源となっています。Thermus thermophilusは高温用途に耐熱性リガーゼを提供し、Pyrococcus furiosusは極端な温度プロセス用に高耐熱性リガーゼを提供します。

リガーゼは、分子クローニングにおける組換えDNA分子の構築に不可欠であり、遺伝子研究やバイオテクノロジー開発を促進します。リガーゼは、ハイスループットなゲノム研究のための次世代シーケンシングや、診断における感度向上のためのリガーゼ連鎖反応技術において役割を果たしています。リガーゼはまた、遺伝子変異の同定、ローリングサークル増幅における環状DNAの増幅、近接ライゲーションアッセイにおけるタンパク質相互作用の検出にも役立っています。ゲノムマッピングのためのライゲーション媒介PCRでは、DNA配列の増幅を促進します。

製薬会社やバイオ製薬会社は、医薬品開発、遺伝子研究、バイオテクノロジー応用のためのリガーゼの主要な消費者です。調査研究機関は様々な分子生物学的実験にリガーゼを利用し、診断研究所は遺伝子疾患や感染症を検出するためのアッセイにリガーゼを利用しています。

北米が最大の市場シェアを占めているのは、高度なヘルスケア・インフラ、多額の研究開発投資、遺伝性疾患やがんの有病率の高さによるものです。アジア太平洋は、ヘルスケア支出の増加、遺伝病に対する意識の高まり、バイオテクノロジー研究活動の拡大により、急成長が見込まれています。

がんや遺伝性疾患の有病率の上昇が、診断・治療用途におけるリガーゼの需要を牽引しています。これらの酵素はDNA修復や複製プロセスにおいて極めて重要だからです。分子診断学の開発とバイオ医薬品産業の成長は、生物製剤と遺伝子治療開発におけるリガーゼの必要性を高めています。

当レポートでは、世界のリガーゼ酵素市場について調査し、市場の概要とともに、製品別、由来別、用途別、エンドユーザー別、地域別の動向、および市場に参入する企業のプロファイルなどを提供しています。

目次

第1章 調査範囲

第2章 調査手法

第3章 エグゼクティブサマリー

第4章 市場指標

第5章 業界の展望

• 業界背景
• 市場力学
• COVID-19の影響
• 社会政治的影響
• ポーターのファイブフォース分析
• イノベーションとテクノロジーの動向
• 経済と規制への影響
• 市場参入戦略

第6章 競合情勢

• 市場参入企業とその提供品のリスト
• 主要参入企業の競合ベンチマーキング
• 主要参入企業の製品ベンチマーク
• 主要参入企業による最近の戦略的展開
• 企業リーダーシップマトリックス

第7章 世界市場

• 概要
• 市場収益、製品別（2019年～2032年）
• 市場収益、由来別（2019年～2032年）
• 市場収益、用途別（2019年～2032年）
• 市場収益、エンドユーザー別（2019年～2032年）
• 市場収益、地域別（2019年～2032年）

第8章 北米市場

第9章 欧州市場

第10章 アジア太平洋市場

第11章 ラテンアメリカ市場

第12章 中東・アフリカ市場

第13章 米国市場

第14章 カナダ市場

第15章 ドイツ市場

第16章 英国市場

第17章 フランス市場

第18章 イタリア市場

第19章 スペイン市場

第20章 日本市場

第21章 中国市場

第22章 インド市場

第23章 韓国市場

第24章 オーストラリア市場

第25章 ブラジル市場

第26章 メキシコ市場

第27章 サウジアラビア市場

第28章 南アフリカ市場

第29章 UAE市場

第30章 企業プロファイル

第31章 付録

The global ligases enzyme market is projected to grow from $442.1 million in 2024 to $727.4 million by 2032, reflecting a compound annual growth rate (CAGR) of 6.6%. This growth is driven by the increasing importance of diagnosing genetic abnormalities and infectious diseases, as well as the rising prevalence of cancer worldwide. Ligases enzymes are essential in various applications, including molecular diagnostics, gene editing, and biopharmaceutical production, where precision medicine and personalized treatment approaches are rapidly advancing.

Key Insights

Quick ligase enhances efficiency in molecular cloning and genetic engineering applications by enabling rapid ligation of DNA fragments. T4 DNA ligase is widely used for joining DNA fragments in cloning and sequencing, while E. coli DNA ligase is crucial for DNA repair and replication studies. Tth DNA ligase is employed in ligase chain reaction techniques for detecting specific DNA sequences. T4 RNA ligase is used in RNA research for ligating single-stranded RNA, and Pfu DNA ligase is applied in high-fidelity DNA amplification and cloning for genetic analyses.

Enzymes derived from archaebacterium are known for their stability under extreme conditions, making them beneficial in industrial applications. Escherichia coli is a common source for ligases due to ease of production and wide applicability in research and diagnostics. Thermus thermophilus provides thermostable ligases for high-temperature applications, while Pyrococcus furiosus offers highly thermostable ligases for extreme temperature processes.

Ligases are essential for constructing recombinant DNA molecules in molecular cloning, facilitating genetic research and biotechnology developments. They play a role in next-generation sequencing for high-throughput genomics studies and in ligase chain reaction techniques for enhanced sensitivity in diagnostics. Ligases also assist in identifying genetic mutations, amplifying circular DNA in rolling circle amplification, and detecting protein interactions in proximity ligation assays. They facilitate amplification of DNA sequences in ligation-mediated PCR for genomic mapping.

Pharmaceutical and biopharmaceutical companies are major consumers of ligases for drug development, genetic research, and biotechnological applications. Research laboratories utilize ligases in various molecular biology experiments, while diagnostic laboratories employ them in assays for detecting genetic disorders and infectious diseases.

North America holds the largest market share due to advanced healthcare infrastructure, significant R&D investments, and a high prevalence of genetic disorders and cancer. Asia-Pacific is expected to experience the fastest growth, driven by increasing healthcare expenditures, rising awareness of genetic diseases, and expanding biotechnological research activities.

Rising prevalence of cancer and genetic disorders drives the demand for ligases in diagnostic and therapeutic applications, as these enzymes are crucial in DNA repair and replication processes. Advancements in molecular diagnostics and the growth of the biopharmaceutical industry amplify the need for ligases in biologics and gene therapy development.

Ligases are vital components in gene editing technologies like CRISPR, enabling precise genetic modifications for therapeutic purposes. Innovations in high-fidelity ligases with improved accuracy and efficiency further enhance their applicability in research and clinical settings.

The market is fragmented, with key players focusing on product innovation, strategic partnerships, and mergers and acquisitions to strengthen their position.

Table of Contents

Chapter 1. Research Scope

• 1.1. Research Objectives
• 1.2. Market Definition
• 1.3. Analysis Period
• 1.4. Market Size Breakdown by Segments
  • 1.4.1. Market Size Breakdown, by Product
  • 1.4.2. Market Size Breakdown, by Source
  • 1.4.3. Market Size Breakdown, by Application
  • 1.4.4. Market Size Breakdown, by End User
  • 1.4.5. Market Size Breakdown, by Region
  • 1.4.6. Market Size Breakdown, by Country
• 1.5. Market Data Reporting Unit
  • 1.5.1. Revenue
• 1.6. Key Stakeholders

Chapter 2. Research Methodology

• 2.1. Secondary Research
  • 2.1.1. Paid
  • 2.1.2. Unpaid
  • 2.1.3. P&S Intelligence Database
• 2.2. Primary Research
• 2.3. Market Size Estimation
• 2.4. Data Triangulation
• 2.5. Currency Conversion Rates
• 2.6. Assumptions for the Study
• 2.7. Notes and Caveats

Chapter 3. Executive Summary

Chapter 4. Market Indicators

Chapter 5. Industry Outlook

• 5.1. Industry Background
• 5.2. Market Dynamics
  • 5.2.1. Trends
  • 5.2.2. Drivers
  • 5.2.3. Restraints/Challenges
  • 5.2.4. Emerging Economies and Key Opportunities
  • 5.2.5. Impact Analysis of Drivers/Restraints
• 5.3. Impact of COVID-19
• 5.4. Sociopolitical Impact
• 5.5. Porter's Five Forces Analysis
  • 5.5.1. Bargaining Power of Buyers
  • 5.5.2. Bargaining Power of Suppliers
  • 5.5.3. Threat of New Entrants
  • 5.5.4. Intensity of Rivalry
  • 5.5.5. Threat of Substitutes
• 5.6. Innovation and Technology Trends
• 5.7. Economic and Regulatory Impact
• 5.8. Market Entry Strategies

Chapter 6. Competitive Landscape

• 6.1. List of Market Players and their Offerings
• 6.2. Competitive Benchmarking of Key Players
• 6.3. Product Benchmarking of Key Players
• 6.4. Recent Strategic Developments by Key Players
• 6.5. Company Leadership Matrix

Chapter 7. Global Market

• 7.1. Overview
• 7.2. Market Revenue, by Product (2019-2032)
• 7.3. Market Revenue, by Source (2019-2032)
• 7.4. Market Revenue, by Application (2019-2032)
• 7.5. Market Revenue, by End User (2019-2032)
• 7.6. Market Revenue, by Region (2019-2032)

Chapter 8. North America Market

• 8.1. Overview
• 8.2. Market Revenue, by Product (2019-2032)
• 8.3. Market Revenue, by Source (2019-2032)
• 8.4. Market Revenue, by Application (2019-2032)
• 8.5. Market Revenue, by End User (2019-2032)
• 8.6. Market Revenue, by Country (2019-2032)

Chapter 9. Europe Market

• 9.1. Overview
• 9.2. Market Revenue, by Product (2019-2032)
• 9.3. Market Revenue, by Source (2019-2032)
• 9.4. Market Revenue, by Application (2019-2032)
• 9.5. Market Revenue, by End User (2019-2032)
• 9.6. Market Revenue, by Country (2019-2032)

Chapter 10. Asia-Pacific Market

• 10.1. Overview
• 10.2. Market Revenue, by Product (2019-2032)
• 10.3. Market Revenue, by Source (2019-2032)
• 10.4. Market Revenue, by Application (2019-2032)
• 10.5. Market Revenue, by End User (2019-2032)
• 10.6. Market Revenue, by Country (2019-2032)

Chapter 11. Latin America Market

• 11.1. Overview
• 11.2. Market Revenue, by Product (2019-2032)
• 11.3. Market Revenue, by Source (2019-2032)
• 11.4. Market Revenue, by Application (2019-2032)
• 11.5. Market Revenue, by End User (2019-2032)
• 11.6. Market Revenue, by Country (2019-2032)

Chapter 12. Middle East and Africa Market

• 12.1. Overview
• 12.2. Market Revenue, by Product (2019-2032)
• 12.3. Market Revenue, by Source (2019-2032)
• 12.4. Market Revenue, by Application (2019-2032)
• 12.5. Market Revenue, by End User (2019-2032)
• 12.6. Market Revenue, by Country (2019-2032)

Chapter 13. U.S. Market

• 13.1. Overview
• 13.2. Economic Indicators
• 13.3. Demographics and Population Insights
• 13.4. Regional Hotspots
• 13.5. Growth Drivers
• 13.6. Challenges and Barriers
• 13.7. Competitive Strategies
• 13.8. Emerging Players
• 13.9. Compliance Requirements
• 13.10. Emerging Investment Areas
• 13.11. Market Size and Forecast
  • 13.11.1. Market Revenue, by Product (2019-2032)
  • 13.11.2. Market Revenue, by Source (2019-2032)
  • 13.11.3. Market Revenue, by Application (2019-2032)
  • 13.11.4. Market Revenue, by End User (2019-2032)

Chapter 14. Canada Market

• 14.1. Overview
• 14.2. Economic Indicators
• 14.3. Demographics and Population Insights
• 14.4. Regional Hotspots
• 14.5. Growth Drivers
• 14.6. Challenges and Barriers
• 14.7. Competitive Strategies
• 14.8. Emerging Players
• 14.9. Compliance Requirements
• 14.10. Emerging Investment Areas
• 14.11. Market Size and Forecast
  • 14.11.1. Market Revenue, by Product (2019-2032)
  • 14.11.2. Market Revenue, by Source (2019-2032)
  • 14.11.3. Market Revenue, by Application (2019-2032)
  • 14.11.4. Market Revenue, by End User (2019-2032)

Chapter 15. Germany Market

• 15.1. Overview
• 15.2. Economic Indicators
• 15.3. Demographics and Population Insights
• 15.4. Regional Hotspots
• 15.5. Growth Drivers
• 15.6. Challenges and Barriers
• 15.7. Competitive Strategies
• 15.8. Emerging Players
• 15.9. Compliance Requirements
• 15.10. Emerging Investment Areas
• 15.11. Market Size and Forecast
  • 15.11.1. Market Revenue, by Product (2019-2032)
  • 15.11.2. Market Revenue, by Source (2019-2032)
  • 15.11.3. Market Revenue, by Application (2019-2032)
  • 15.11.4. Market Revenue, by End User (2019-2032)

Chapter 16. U.K. Market

• 16.1. Overview
• 16.2. Economic Indicators
• 16.3. Demographics and Population Insights
• 16.4. Regional Hotspots
• 16.5. Growth Drivers
• 16.6. Challenges and Barriers
• 16.7. Competitive Strategies
• 16.8. Emerging Players
• 16.9. Compliance Requirements
• 16.10. Emerging Investment Areas
• 16.11. Market Size and Forecast
  • 16.11.1. Market Revenue, by Product (2019-2032)
  • 16.11.2. Market Revenue, by Source (2019-2032)
  • 16.11.3. Market Revenue, by Application (2019-2032)
  • 16.11.4. Market Revenue, by End User (2019-2032)

Chapter 17. France Market

• 17.1. Overview
• 17.2. Economic Indicators
• 17.3. Demographics and Population Insights
• 17.4. Regional Hotspots
• 17.5. Growth Drivers
• 17.6. Challenges and Barriers
• 17.7. Competitive Strategies
• 17.8. Emerging Players
• 17.9. Compliance Requirements
• 17.10. Emerging Investment Areas
• 17.11. Market Size and Forecast
  • 17.11.1. Market Revenue, by Product (2019-2032)
  • 17.11.2. Market Revenue, by Source (2019-2032)
  • 17.11.3. Market Revenue, by Application (2019-2032)
  • 17.11.4. Market Revenue, by End User (2019-2032)

Chapter 18. Italy Market

• 18.1. Overview
• 18.2. Economic Indicators
• 18.3. Demographics and Population Insights
• 18.4. Regional Hotspots
• 18.5. Growth Drivers
• 18.6. Challenges and Barriers
• 18.7. Competitive Strategies
• 18.8. Emerging Players
• 18.9. Compliance Requirements
• 18.10. Emerging Investment Areas
• 18.11. Market Size and Forecast
  • 18.11.1. Market Revenue, by Product (2019-2032)
  • 18.11.2. Market Revenue, by Source (2019-2032)
  • 18.11.3. Market Revenue, by Application (2019-2032)
  • 18.11.4. Market Revenue, by End User (2019-2032)

Chapter 19. Spain Market

• 19.1. Overview
• 19.2. Economic Indicators
• 19.3. Demographics and Population Insights
• 19.4. Regional Hotspots
• 19.5. Growth Drivers
• 19.6. Challenges and Barriers
• 19.7. Competitive Strategies
• 19.8. Emerging Players
• 19.9. Compliance Requirements
• 19.10. Emerging Investment Areas
• 19.11. Market Size and Forecast
  • 19.11.1. Market Revenue, by Product (2019-2032)
  • 19.11.2. Market Revenue, by Source (2019-2032)
  • 19.11.3. Market Revenue, by Application (2019-2032)
  • 19.11.4. Market Revenue, by End User (2019-2032)

Chapter 20. Japan Market

• 20.1. Overview
• 20.2. Economic Indicators
• 20.3. Demographics and Population Insights
• 20.4. Regional Hotspots
• 20.5. Growth Drivers
• 20.6. Challenges and Barriers
• 20.7. Competitive Strategies
• 20.8. Emerging Players
• 20.9. Compliance Requirements
• 20.10. Emerging Investment Areas
• 20.11. Market Size and Forecast
  • 20.11.1. Market Revenue, by Product (2019-2032)
  • 20.11.2. Market Revenue, by Source (2019-2032)
  • 20.11.3. Market Revenue, by Application (2019-2032)
  • 20.11.4. Market Revenue, by End User (2019-2032)

Chapter 21. China Market

• 21.1. Overview
• 21.2. Economic Indicators
• 21.3. Demographics and Population Insights
• 21.4. Regional Hotspots
• 21.5. Growth Drivers
• 21.6. Challenges and Barriers
• 21.7. Competitive Strategies
• 21.8. Emerging Players
• 21.9. Compliance Requirements
• 21.10. Emerging Investment Areas
• 21.11. Market Size and Forecast
  • 21.11.1. Market Revenue, by Product (2019-2032)
  • 21.11.2. Market Revenue, by Source (2019-2032)
  • 21.11.3. Market Revenue, by Application (2019-2032)
  • 21.11.4. Market Revenue, by End User (2019-2032)

Chapter 22. India Market

• 22.1. Overview
• 22.2. Economic Indicators
• 22.3. Demographics and Population Insights
• 22.4. Regional Hotspots
• 22.5. Growth Drivers
• 22.6. Challenges and Barriers
• 22.7. Competitive Strategies
• 22.8. Emerging Players
• 22.9. Compliance Requirements
• 22.10. Emerging Investment Areas
• 22.11. Market Size and Forecast
  • 22.11.1. Market Revenue, by Product (2019-2032)
  • 22.11.2. Market Revenue, by Source (2019-2032)
  • 22.11.3. Market Revenue, by Application (2019-2032)
  • 22.11.4. Market Revenue, by End User (2019-2032)

Chapter 23. South Korea Market

• 23.1. Overview
• 23.2. Economic Indicators
• 23.3. Demographics and Population Insights
• 23.4. Regional Hotspots
• 23.5. Growth Drivers
• 23.6. Challenges and Barriers
• 23.7. Competitive Strategies
• 23.8. Emerging Players
• 23.9. Compliance Requirements
• 23.10. Emerging Investment Areas
• 23.11. Market Size and Forecast
  • 23.11.1. Market Revenue, by Product (2019-2032)
  • 23.11.2. Market Revenue, by Source (2019-2032)
  • 23.11.3. Market Revenue, by Application (2019-2032)
  • 23.11.4. Market Revenue, by End User (2019-2032)

Chapter 24. Australia Market

• 24.1. Overview
• 24.2. Economic Indicators
• 24.3. Demographics and Population Insights
• 24.4. Regional Hotspots
• 24.5. Growth Drivers
• 24.6. Challenges and Barriers
• 24.7. Competitive Strategies
• 24.8. Emerging Players
• 24.9. Compliance Requirements
• 24.10. Emerging Investment Areas
• 24.11. Market Size and Forecast
  • 24.11.1. Market Revenue, by Product (2019-2032)
  • 24.11.2. Market Revenue, by Source (2019-2032)
  • 24.11.3. Market Revenue, by Application (2019-2032)
  • 24.11.4. Market Revenue, by End User (2019-2032)

Chapter 25. Brazil Market

• 25.1. Overview
• 25.2. Economic Indicators
• 25.3. Demographics and Population Insights
• 25.4. Regional Hotspots
• 25.5. Growth Drivers
• 25.6. Challenges and Barriers
• 25.7. Competitive Strategies
• 25.8. Emerging Players
• 25.9. Compliance Requirements
• 25.10. Emerging Investment Areas
• 25.11. Market Size and Forecast
  • 25.11.1. Market Revenue, by Product (2019-2032)
  • 25.11.2. Market Revenue, by Source (2019-2032)
  • 25.11.3. Market Revenue, by Application (2019-2032)
  • 25.11.4. Market Revenue, by End User (2019-2032)

Chapter 26. Mexico Market

• 26.1. Overview
• 26.2. Economic Indicators
• 26.3. Demographics and Population Insights
• 26.4. Regional Hotspots
• 26.5. Growth Drivers
• 26.6. Challenges and Barriers
• 26.7. Competitive Strategies
• 26.8. Emerging Players
• 26.9. Compliance Requirements
• 26.10. Emerging Investment Areas
• 26.11. Market Size and Forecast
  • 26.11.1. Market Revenue, by Product (2019-2032)
  • 26.11.2. Market Revenue, by Source (2019-2032)
  • 26.11.3. Market Revenue, by Application (2019-2032)
  • 26.11.4. Market Revenue, by End User (2019-2032)

Chapter 27. Saudi Arabia Market

• 27.1. Overview
• 27.2. Economic Indicators
• 27.3. Demographics and Population Insights
• 27.4. Regional Hotspots
• 27.5. Growth Drivers
• 27.6. Challenges and Barriers
• 27.7. Competitive Strategies
• 27.8. Emerging Players
• 27.9. Compliance Requirements
• 27.10. Emerging Investment Areas
• 27.11. Market Size and Forecast
  • 27.11.1. Market Revenue, by Product (2019-2032)
  • 27.11.2. Market Revenue, by Source (2019-2032)
  • 27.11.3. Market Revenue, by Application (2019-2032)
  • 27.11.4. Market Revenue, by End User (2019-2032)

Chapter 28. South Africa Market

• 28.1. Overview
• 28.2. Economic Indicators
• 28.3. Demographics and Population Insights
• 28.4. Regional Hotspots
• 28.5. Growth Drivers
• 28.6. Challenges and Barriers
• 28.7. Competitive Strategies
• 28.8. Emerging Players
• 28.9. Compliance Requirements
• 28.10. Emerging Investment Areas
• 28.11. Market Size and Forecast
  • 28.11.1. Market Revenue, by Product (2019-2032)
  • 28.11.2. Market Revenue, by Source (2019-2032)
  • 28.11.3. Market Revenue, by Application (2019-2032)
  • 28.11.4. Market Revenue, by End User (2019-2032)

Chapter 29. U.A.E. Market

• 29.1. Overview
• 29.2. Economic Indicators
• 29.3. Demographics and Population Insights
• 29.4. Regional Hotspots
• 29.5. Growth Drivers
• 29.6. Challenges and Barriers
• 29.7. Competitive Strategies
• 29.8. Emerging Players
• 29.9. Compliance Requirements
• 29.10. Emerging Investment Areas
• 29.11. Market Size and Forecast
  • 29.11.1. Market Revenue, by Product (2019-2032)
  • 29.11.2. Market Revenue, by Source (2019-2032)
  • 29.11.3. Market Revenue, by Application (2019-2032)
  • 29.11.4. Market Revenue, by End User (2019-2032)

Chapter 30. Company Profiles

Chapter 31. Appendix

• 31.1. Sources and References
• 31.2. Related Reports