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市場調査レポート
商品コード
1380413
ペプチド薬物複合体の世界市場:2023年~2030年Global Peptide Drug Conjugates Market 2023-2030 |
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カスタマイズ可能
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ペプチド薬物複合体の世界市場:2023年~2030年 |
出版日: 2023年09月27日
発行: Orion Market Research
ページ情報: 英文 200 Pages
納期: 2~3営業日
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ペプチド薬物複合体の世界市場は予測期間(2023年~2030年)にCAGR 9.4%で成長すると予測されます。この市場の背景には、がんや代謝性疾患の有病率の増加、新薬の研究開発投資の増加、医薬品開発の技術進歩などがあります。Globocan 2020によると、がん患者数は5,055万287人です。そのうち1,929万2,789人が新たにがんと診断されました。
製品の中でも、メルフルフェンのサブセグメントが世界のペプチド薬物複合体市場でかなりのシェアを占めると予想されています。このセグメントの成長は、現在の治療オプションに関する認知度の向上、有利な償還政策、メルフルフェンの発売、がん治療におけるPDC薬剤の急速な普及に起因しています。2021年2月、FDAは、デキサメタゾンとの併用で使用する最初の抗がんペプチド薬物複合体、メルファランフルフェナミド(メルフルフェン)を承認しました。第2相HORIZON調査に基づき、スウェーデンのバイオテクノロジー企業Oncopeptides ABが開発したこの製品は、早期承認を受けた。本剤は、4種類以上の前治療歴があり、少なくとも1種類のプロテアソーム阻害剤、1種類の免疫調節剤、および1種類のCD38指向性モノクローナル抗体に抵抗性を示す難治性多発性骨髄腫の成人患者を対象としています。
ペプチド薬物複合体の世界市場は、北米(米国、カナダ)、欧州(英国、イタリア、スペイン、ドイツ、フランス、その他欧州地域)、アジア太平洋地域(インド、中国、日本、韓国、その他アジア地域)、世界のその他の地域(中東とアフリカ、中南米)を含む地域別にさらに細分化されます。なかでもアジア太平洋地域は、新しい送達システムを開発・商業化するための投資が増加していることから、世界全体で突出したシェアを占めると予想されます。
すべての地域の中で、北米地域は予測期間中にかなりのCAGRで成長すると予想されています。北米市場を牽引する主な要因は、同地域全体でがん患者が増加していることであり、今後数年間はペプチド薬物複合体市場の成長に確実に影響を与えると推定されます。米国がん協会(ACS)によると、2022年には米国で約191万8,030人の新規がん患者と60万9,360人のがん死亡者が報告されました。Royal Society Publishing Organizationの報告によると、ハイブリッドペプチドであるHPRP-A1-TATは、細胞膜を破壊して細胞質の内容物を急速に漏出させることができ、強い抗がん作用を持つ。
Title: Global Peptide Drug Conjugates Market Size, Share & Trends Analysis Report by Type (Diagnostic and Therapeutic), and by Product (Melflufen, Lutetium, ANG1005, BT1718 and CBX-12),Forecast Period (2023-2030).
The global peptide drug conjugates market is anticipated to grow at a CAGR of 9.4% during the Forecast Period (2023-2030). The market is attributed to factors including the increasing prevalence of cancer and metabolic disorders, rising investments in the R&D of novel drugs, and technological advancements in drug development. According to the Globocan 2020, number of cancer cases were 50,550,287. Of which, the total number of new cases 19,292,789 around the globe.
The global peptide drug conjugates market is segmented on the type, and product. Based on the type, the market is sub-segmented into diagnostic and therapeutic. Based on the product, the market is sub-segmented into melflufen, lutetium, ANG1005, BT1718 and CBX-12. Among the type, the therapeutic sub-segment is anticipated to hold a considerable share of the market, owing to the emerging targeted therapeutic that present increased tumor penetration and selectivity.
Among the product, the melflufen sub-segment is expected to hold a considerable share of the global Peptide Drug Conjugates market. The segmental growth is attributed to the owing to increasing awareness about current treatment options, favorable reimbursement policies, the launch of Melflufen and rapid uptake of PDC drugs in cancer therapy., In February 2021, the FDA approved the first anticancer peptide-drug conjugate, melphalan flufenamide, or melflufen, for use in combination with dexamethasone. Based on the phase 2 HORIZON research, the product, developed by the Swedish biotech company Oncopeptides AB, received accelerated approval. In adult patients with refractory multiple myeloma, who have received at least 4 prior lines of therapy and whose disease is refractory to at least 1 proteasome inhibitor, 1 immunomodulatory agent, and 1 CD38-directed monoclonal antibody.
The global peptide drug conjugates market is further segmented based on geography including North America (the US, and Canada), Europe (UK, Italy, Spain, Germany, France, and the Rest of Europe), Asia-Pacific (India, China, Japan, South Korea, and Rest of Asia), and the Rest of the World (the Middle East & Africa, and Latin America). Among these, Asia-Pacific is anticipated to hold a prominent share of the market across the globe, owing to the rising investments to develop and commercialize new delivery systems.
Among all regions, the North America regions is anticipated to grow at a considerable CAGR over the forecast period. The major factors driving the North America market is the increasing number of cancer cases across the region is estimated to certainly impact the peptide drug conjugates market growth in upcoming years. According to the American Cancer Society (ACS), in 2022, around 1,918,030 new cancer cases and 609,360 cancer mortalities were reported in the US. As per the reports of Royal Society Publishing Organization, HPRP-A1-TAT, a hybrid peptide, can destroy the cell membrane to cause rapid leakage of cytoplasmic contents, and has a strong anti-cancer activity.
The major companies serving the global peptide drug conjugates market include: Angiochem Inc., Bicycle Therapeutics, Inc., Cybrexa Therapeutics Inc., Novartis AG, Oncopeptides AB, and others. The market players are considerably contributing to the market growth by the adoption of various strategies including mergers and acquisitions, partnerships, collaborations, funding, and new product launches, to stay competitive in the market. For instance, in September 2023, PeptiDream Inc., a public Kanagawa, Japan-based biopharmaceutical company entered into a new multi-target collaboration and license agreement with US based Genentech, a member of the Roche Group, targeted on the discovery and development of novel macrocyclic peptide-radioisotope drug conjugates.