アップストリームバイオプロセスの世界市場：2023-2030年

世界のアップストリームバイオプロセス市場は、予測期間（2023-2030年）にCAGR 11.1％で成長すると予測されています。プロセス制御の改善、製品品質の向上、ばらつきの低減、スループットと効率の向上、コスト削減など、自動化アップストリームバイオプロセスの利点の増加が市場成長の原動力となっています。改良されたソフトウェアによる自動化アップストリームバイオプロセスの採用拡大が、世界の市場成長を支える主要因です。バイオ生産ラボで直接データを取得することで、バイオプロセスエンジニアはプロセス理解を深めることができ、より堅牢な製造プロセスと開発期間の短縮につながります。様々な上流のバイオリアクターは、ルーチンの製品品質と細胞培養培地分析を自動化します。それゆえ、市場プレーヤーは自動化されたアップストリームバイオプロセスソリューションの市場投入にも注力しており、市場成長をさらに後押ししています。例えば、2023年9月、Waters Corp.は、生物学的サンプルの前処理と分析をさらに簡素化するように設計された新しいバイオプロセスウォークアップ・ソリューションを発表しました。バイオリアクターサンプルを分析用に中央ラボに送る必要性をなくすことで、この新しいソリューションは上流のバイオプロセスの加速をさらに容易にします。Waters OneLab（TM）ラボラトリーオートメーションソフトウェアと新しく開発された分析ワークフローにより、バイオプロセスエンジニアは高品質なバイオプロセスを実現することができます。

セグメント別の展望

細胞培養製品は世界のアップストリームバイオプロセス市場で大きなシェアを占めると予測される

製品の中でも、細胞培養製品は世界のアップストリームバイオプロセス市場でかなりのシェアを占めると予想されています。このセグメントの成長は、細胞培養が生存し増殖するために必要な栄養素を供給する培地を必要とする研究室での細胞株の開発の影響力が高まっていることに起因しています。成長培地はまた、適切な浸透圧とpHを提供します。CAR T細胞の製造は従来、動物やヒトの血清の使用に頼ってきたが、この血清は変動が大きく、不純物を含む可能性があります。血清は、厳格な安全性試験、スクリーニング、適切な品質のバッチの備蓄を必要とし、よりコストと時間のかかる製造プロセスとなります。例えば、2023年5月、ロンザ・グループ・リミテッドは、CAR T細胞製造を最適化するために開発された新規の化学的定義培地であるTheraPEAK（R）T-VIVO（R）細胞培養培地を発売しました。動物由来成分を含まないこの培地は、一貫性と工程管理を向上させ、規制当局の承認を簡素化し、市場投入までの時間を短縮します。

地域別展望

世界のアップストリームバイオプロセス市場は、北米（米国、カナダ）、欧州（英国、イタリア、スペイン、ドイツ、フランス、その他欧州地域）、アジア太平洋地域（インド、中国、日本、韓国、その他アジア地域）、世界のその他の地域（中東とアフリカ、中南米）を含む地域別にさらに細分化されます。なかでもアジア太平洋地域は、急速な技術進歩のため、研究開発に重点を置きながら製品の改良に絶えず取り組んでおり、世界全体で大きなシェアを占めると予想されています。主な市場プレイヤーとしては、BioSpectrum, Inc.、Fujifilm Holdings Corp.、Hash Biotech Labs、Samsung Biologicsなどが挙げられます。

北米地域は世界のアップストリームバイオプロセス市場で大きなCAGRで成長する見込み

すべての地域の中で、北米地域は予測期間中にかなりのCAGRで成長すると予測されています。この地域の成長は、大手バイオ製薬企業の存在、新規生体分子・mAbsの研究開発への投資の増加、慢性疾患負担の増加、発達したインフラの存在が、この地域の市場成長を促進する主な要因となっています。さらに、安全で費用対効果が高く、規制に準拠した臨床用途の細胞由来製品の製造を可能にする自動バイオリアクターの開発が、この地域の成長を後押ししています。

この地域のアップストリームバイオプロセス市場は、バイオシミラー/バイオ分子、モノクローナル抗体、微小治療用ペプチドの生産に関する研究の増加によって加速しています。プロセスの改善とクリーンで安全かつ効果的な生体分子生産への需要が、市場の拡大を後押ししています。特許取得済みの細胞株を採用する企業は、細胞培養プロセスで高い成功率を達成し、規制リスクを最小限に抑え、効率的な商業生産を可能にします。主な市場プレイヤーには、Corning Inc.、Patheon N.V.、PBS Biotech, Inc.、Thermo Fisher Scientific, Inc.などがいます。

目次

第1章 レポート概要

• 業界の現状分析と成長ポテンシャルの展望
• 調査方法とツール
• 市場内訳
  • セグメント別
  • 地域別

第2章 市場概要と洞察

• 調査範囲
• アナリストの洞察と現在の市場動向
  • 主な調査結果
  • 推奨事項
  • 結論

第3章 競合情勢

• 主要企業分析
• Corning, Inc.
  • 概要
  • 財務分析
  • SWOT分析
• Sartorius AG
  • 概要
  • 財務分析
  • SWOT分析
  • 最近の動向
• Thermo Fisher Scientific Inc.
  • 概要
  • 財務分析
  • SWOT分析
  • 最近の動向
• 主要戦略分析

第4章 市場セグメンテーション

• アップストリームバイオプロセスの世界市場：製品別
  • バイオリアクター
  • 細胞培養製品
  • フィルター
  • バッグと容器
  • その他（バイオリアクターアクセサリー）
• アップストリームバイオプロセスの世界市場：ワークフロー別
  • 培地調製
  • 細胞培養
  • 細胞分離
• アップストリームバイオプロセスの世界市場：用途タイプ別
  • マルチユース
  • シングルユース

第5章 地域分析

• 北米
  • 米国
  • カナダ
• 欧州
  • 英国
  • ドイツ
  • イタリア
  • スペイン
  • フランス
  • その他欧州
• アジア太平洋
  • 中国
  • インド
  • 日本
  • 韓国
  • その他アジア太平洋地域
• 世界のその他の地域

第6章 企業プロファイル

• AGC Inc.
• Applikon Biotechnology
• Bio-Connect Inc.
• BioProcess International
• Boehringer Ingelheim GmbH
• CellGenix GmbH
• Cytiva LifeScience
• Danaher Corp.
• Eppendorf AG
• Esco Pharma
• Getinge AB
• Infors HT
• Lonza Group Ltd.
• Merck KGaA
• Pall Corp.
• PBS Biotech, Inc.
• VWR International, LLC

LIST OF TABLES

• 1. GLOBAL UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2022-2030 ($ MILLION)
• 2. GLOBAL UPSTREAM BIOPROCESSING BIOREACTORS MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 3. GLOBAL UPSTREAM BIOPROCESSING CELL CULTURE PRODUCTS MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 4. GLOBAL UPSTREAM BIOPROCESSING FILTERS MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 5. GLOBAL UPSTREAM BIOPROCESSING BAGS AND CONTAINERS MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 6. GLOBAL UPSTREAM BIOPROCESSING OTHERS PRODUCT MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 7. GLOBAL UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY WORKFLOW, 2022-2030 ($ MILLION)
• 8. GLOBAL UPSTREAM MEDIA PREPARATION BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 9. GLOBAL UPSTREAM CELL CULTURE BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 10. GLOBAL UPSTREAM CELL SEPARATION BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 11. GLOBAL UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY USE TYPE, 2022-2030 ($ MILLION)
• 12. GLOBAL UPSTREAM BIOPROCESSING FOR MULTI-USE MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 13. GLOBAL UPSTREAM BIOPROCESSING FOR SINGLE-USE MARKET RESEARCH AND ANALYSIS BY REGION,2022-2030 ($ MILLION)
• 14. GLOBAL UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY REGION, 2022-2030 ($ MILLION)
• 15. NORTH AMERICAN UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2022-2030 ($ MILLION)
• 16. NORTH AMERICAN UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2022-2030 ($ MILLION)
• 17. NORTH AMERICAN UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY WORKFLOW, 2022-2030 ($ MILLION)
• 18. NORTH AMERICAN UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY USE TYPE, 2022-2030 ($ MILLION)
• 19. EUROPEAN UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2022-2030 ($ MILLION)
• 20. EUROPEAN UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2022-2030 ($ MILLION)
• 21. EUROPEAN UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY WORKFLOW, 2022-2030 ($ MILLION)
• 22. EUROPEAN UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY USE TYPE, 2022-2030 ($ MILLION)
• 23. ASIA- PACIFIC UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2022-2030 ($ MILLION)
• 24. ASIA- PACIFIC UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2022-2030 ($ MILLION)
• 25. ASIA- PACIFIC UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY WORKFLOW, 2022-2030 ($ MILLION)
• 26. ASIA- PACIFIC UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY USE TYPE, 2022-2030 ($ MILLION)
• 27. REST OF THE WORLD UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2022-2030 ($ MILLION)
• 28. REST OF THE WORLD UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2022-2030 ($ MILLION)
• 29. REST OF THE WORLD UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY WORK FLOW, 2022-2030 ($ MILLION)
• 30. REST OF THE WORLD UPSTREAM BIOPROCESSING MARKET RESEARCH AND ANALYSIS BY USE TYPE, 2022-2030 ($ MILLION)

LIST OF FIGURES

• 1. GLOBAL UPSTREAM BIOPROCESSING MARKET SHAREBY PRODUCT, 2022 VS 2030 (%)
• 2. GLOBAL UPSTREAM BIOPROCESSING BIOREACTORS MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 3. GLOBAL UPSTREAM BIOPROCESSING CELL CULTURE PRODUCTS MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 4. GLOBAL UPSTREAM BIOPROCESSING FILTERS MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 5. GLOBAL UPSTREAM BIOPROCESSING BAGS AND CONTAINERS MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 6. GLOBAL UPSTREAM BIOPROCESSING OTHERS PRODUCT MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 7. GLOBAL UPSTREAM BIOPROCESSING MARKET SHAREBY WORKFLOW, 2022 VS 2030 (%)
• 8. GLOBAL UPSTREAM MEDIA PREPARATION BIOPROCESSING MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 9. GLOBAL UPSTREAM CELL CULTURE BIOPROCESSING MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 10. GLOBAL UPSTREAM CELL SEPARATION BIOPROCESSING MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 11. GLOBAL UPSTREAM BIOPROCESSING MARKET SHAREBY USE TYPE, 2022 VS 2030 (%)
• 12. GLOBAL UPSTREAM BIOPROCESSING FOR MULTI-USE MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 13. GLOBAL UPSTREAM BIOPROCESSING FOR SINGLE-USE MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 14. GLOBAL UPSTREAM BIOPROCESSING MARKET SHAREBY REGION, 2022 VS 2030 (%)
• 15. US UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 16. CANADA UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 17. UK UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 18. FRANCE UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 19. GERMANY UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 20. ITALY UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 21. SPAIN UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 22. REST OF EUROPE UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 23. INDIA UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 24. CHINA UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 25. JAPAN UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 26. SOUTH KOREA UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 27. REST OF ASIA-PACIFIC UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)
• 28. REST OF THE WORLD UPSTREAM BIOPROCESSING MARKET SIZE, 2022-2030 ($ MILLION)

Title: Global Upstream Bioprocessing Market Size, Share & Trends Analysis Report by Product (Bioreactors, Cell Culture Products, Filters, Bags and Containers and Others), by Workflow (Media Preparation, Cell Culture and Cell Separation), and by Use Type (Multi-Use and Single-Use),Forecast Period (2023-2030).

The global upstream bioprocessing market is anticipated to grow at a CAGR of 11.1% during the Forecast Period (2023-2030). An increase in advantage of automated upstream bioprocessing such as improved process control, enhanced product quality, reduced variability, increased throughput and efficiency, and cost savings drive the growth of market. The growing adoption of automated upstream bioprocessing with improved software is the key factor supporting the growth of the market globally. Capturing data directly at the bio production laboratory can help bioprocess engineers improve process understanding, leading to more robust manufacturing processes and accelerated development timelines. Various upstream bioreactors to automate routine product quality and cell culture media analyses. Hence, the market players are also focusing on launching automated Upstream Bioprocessing solutions that further bolster the market growth. For instance, in September 2023, Waters Corp. launched new bioprocess walk-up solutions designed to further simplify biologic sample prep and analysis. By eliminating the need to send bioreactor samples to a central laboratory for analysis, the new solutions make it even easier to accelerate upstream bioprocess. Waters OneLab™ laboratory automation software and new pre-developed analytical workflow allow bioprocess engineers to capture high-quality bioprocess

Segmental Outlook

The global upstream bioprocessing market is segmented on the product, workflow, and use type. Based on the product, the market is sub-segmented into bioreactors, cell culture products, filters, bags and containers and others (bioreactors accessories). Based on the workflow, the market is sub-segmented into media preparation, cell culture and cell separation. Further, on the basis of use type, the market is sub-segmented into multi-use and single-use. Among the workflow, the media preparation sub-segment is anticipated to hold a considerable share of the market owing to the rise in the development of specific media-formulated cell cultures that significantly impact mammalian cell growth and experimental outcomes. Culture media provide a source of energy for cell growth and compounds that regulate cellular processes.

The Cell Culture Products Sub-Segment is Anticipated to Hold a Considerable Share of the Global Upstream Bioprocessing Market

Among the products, the cell culture products sub-segment is expected to hold a considerable share of the global upstream bioprocessing market. The segmental growth is attributed to the growing influence of the development of cell lines in the lab that require a medium that supplies the nutrients necessary for cell cultures to survive and proliferate. The growth media also provides the correct osmolality and pH. The manufacture of CAR T-cells has traditionally relied on the use of animal or human serum, that is highly variable and may contain adventitious agents. Serum requires stringent safety testing, screening, and stockpiling of suitable-quality batches, making for a more costly and time-consuming manufacturing process. For instance, in May 2023, Lonza Group Ltd. launched the TheraPEAK® T-VIVO® Cell Culture Medium, a novel chemically defined medium developed to optimize CAR T-cell manufacture. Free from animal-origin components, the medium improves consistency and process control and simplifies regulatory approval for faster time-to-market.

Regional Outlook

The global Upstream Bioprocessing market is further segmented based on geography including North America (the US, and Canada), Europe (UK, Italy, Spain, Germany, France, and the Rest of Europe), Asia-Pacific (India, China, Japan, South Korea, and Rest of Asia), and the Rest of the World (the Middle East & Africa, and Latin America. Among these, Asia-Pacific is anticipated to hold a prominent share of the market across the globe, owing to the rapid technological advancements and companies are constantly working towards the improvement of their products with a major focus on research and development. The key market players include BioSpectrum, Inc., Fujifilm Holdings Corp., Hash Biotech Labs, Samsung Biologics and others.

The North America Region is Expected to Grow at a Significant CAGR in the Global Upstream Bioprocessing Market

Among all regions, the North America regions is anticipated to grow at a considerable CAGR over the forecast period. Regional growth is attributed to the presence of major biopharmaceutical companies, increasing investment for research and development of new biomolecules & mAbs, increasing chronic disease burden, and the presence of developed infrastructure are major factors that drive the market growth in this region. Moreover, the development of automated bioreactors for safe, cost-effective, and regulatory-compliant manufacturing of cell-based products for clinical applications has driven the region's growth.

The market for upstream bioprocessing in the region is accelerated by an increase in research into the production of biosimilars/biomolecules, monoclonal antibodies, and tiny therapeutic peptides. The demand for process improvement and clean, secure, and effective biomolecule production fuels results in the market's expansion. Companies adopting patented cell lines result in a high success rate in the cell cultivation process and enable minimal regulatory risk and efficient commercial production. The key market player includes Corning Inc., Patheon N.V., PBS Biotech, Inc., Thermo Fisher Scientific, Inc. and others.

Market Players Outlook

The major companies serving the upstream bioprocessing market include: Corning, Inc., Eppendorf AG, Merck KGaA, Sartorius AG, Thermo Fisher Scientific Inc., and others. The market players are considerably contributing to the market growth by the adoption of various strategies including mergers and acquisitions, partnerships, collaborations, funding, and new product launches, to stay competitive in the market. For instance, in June 2023, Culture Biosciences and Cytiva are collaborating to advance innovation in upstream bioprocessing by providing customers greater access to predictive and robust scale-up capabilities. Together, Cytiva and Culture Biosciences aims to bring to customers new bioprocess solutions that use digitization, in-silico approaches, and virtual monitoring and control of experiments.

The Report Covers:

• Market value data analysis of 2022 and forecast to 2030.
• Annualized market revenues ($ million) for each market segment.
• Country-wise analysis of major geographical regions.
• Key companies operating in the global upstream bioprocessing market. Based on the availability of data, information related to new product launches, and relevant news is also available in the report.
• Analysis of business strategies by identifying the key market segments positioned for strong growth in the future.
• Analysis of market-entry and market expansion strategies.
• Competitive strategies by identifying 'who-stands-where' in the market.

Table of Contents

1. Report Summary

• Current Industry Analysis and Growth Potential Outlook
• 1.1. Research Methods and Tools
• 1.2. Market Breakdown
  • 1.2.1. By Segments
  • 1.2.2. By Region

2. Market Overview and Insights

• 2.1. Scope of the Report
• 2.2. Analyst Insight & Current Market Trends
  • 2.2.1. Key Findings
  • 2.2.2. Recommendations
  • 2.2.3. Conclusion

3. Competitive Landscape

• 3.1. Key Company Analysis
• 3.2. Corning, Inc.
  • 3.2.1. Overview
  • 3.2.2. Financial Analysis
  • 3.2.3. SWOT Analysis
• 3.3. Sartorius AG
  • 3.3.1. Overview
  • 3.3.2. Financial Analysis
  • 3.3.3. SWOT Analysis
  • 3.3.4. Recent Developments
• 3.4. Thermo Fisher Scientific Inc.
  • 3.4.1. Overview
  • 3.4.2. Financial Analysis
  • 3.4.3. SWOT Analysis
  • 3.4.4. Recent Developments
• 3.5. Key Strategy Analysis

4. Market Segmentation

• 4.1. Global Upstream Bioprocessing Market by Product
  • 4.1.1. Bioreactors
  • 4.1.2. Cell Culture Products
  • 4.1.3. Filters
  • 4.1.4. Bags and Containers
  • 4.1.5. Others (Bioreactors Accessories)
• 4.2. Global Upstream Bioprocessing Market by Workflow
  • 4.2.1. Media Preparation
  • 4.2.2. Cell Culture
  • 4.2.3. Cell Separation
• 4.3. Global Upstream Bioprocessing Market by Use Type
  • 4.3.1. Multi-Use
  • 4.3.2. Single-Use

5. Regional Analysis

• 5.1. North America
  • 5.1.1. United States
  • 5.1.2. Canada
• 5.2. Europe
  • 5.2.1. UK
  • 5.2.2. Germany
  • 5.2.3. Italy
  • 5.2.4. Spain
  • 5.2.5. France
  • 5.2.6. Rest of Europe
• 5.3. Asia-Pacific
  • 5.3.1. China
  • 5.3.2. India
  • 5.3.3. Japan
  • 5.3.4. South Korea
  • 5.3.5. Rest of Asia-Pacific
• 5.4. Rest of the World

6. Company Profiles

• 6.1. AGC Inc.
• 6.2. Applikon Biotechnology
• 6.3. Bio-Connect Inc.
• 6.4. BioProcess International
• 6.5. Boehringer Ingelheim GmbH
• 6.6. CellGenix GmbH
• 6.7. Cytiva LifeScience
• 6.8. Danaher Corp.
• 6.9. Eppendorf AG
• 6.10. Esco Pharma
• 6.11. Getinge AB
• 6.12. Infors HT
• 6.13. Lonza Group Ltd.
• 6.14. Merck KGaA
• 6.15. Pall Corp.
• 6.16. PBS Biotech, Inc.
• 6.17. VWR International, LLC