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市場調査レポート
商品コード
1292935
多発性骨髄腫(MM)の世界市場2023-2030Global Multiple Myeloma Market 2023-2030 |
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カスタマイズ可能
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多発性骨髄腫(MM)の世界市場2023-2030 |
出版日: 2023年05月23日
発行: Orion Market Research
ページ情報: 英文 170 Pages
納期: 2~3営業日
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世界の多発性骨髄腫(MM)市場は、予測期間中に4.8%というかなりのCAGRで成長すると予測されています。市場の成長は、多発性骨髄腫(MM)の有病率の増加や診断・治療技術の進歩などの要因に起因しています。例えば、カリフォルニア大学によると、2020年には世界全体で176,404例、95%近くの多発性骨髄腫(MM)の新規症例が報告されました。また、カナダがん協会によると、2022年に新たに診断された骨髄腫患者数は4,000人で、そのうち男性が2,400人、女性が1,550人で、毎日11人近くが骨髄腫と診断されています。しかし、新たに開発された標的治療や移植技術の導入により、多発性骨髄腫(MM)の発症率は低下しています。例えば、2023年2月、Memorial Sloan Kettering Cancer Center(MSK)の研究者らは、再発性多発性骨髄腫(MM)の患者が、疾患の経過の早い段階でキメラ抗原受容体(CAR)T療法を受けることで恩恵を受けるという臨床試験の結果を発表しました。この治療では、完全寛解率が7倍近く増加し、治療後に体内でがんは検出されませんでした。
タイプ別セグメントのうち、Hyperdiploid(HMM)サブセグメントは予測期間中に大きな成長を記録すると予測されています。HMMサブセグメントの成長は、研究開発活動の増加や個別化医療に対する需要の高まりなどの要因によるものです。例えば、2021年にJanssen Biotech, Inc.は、新規診断または再発/難治性多発性骨髄腫(MM)患者の治療薬としてDARZALEX FASPRO(daratumumab・hyaluronidase-fihj)の米国FDA承認を発表しました。
同地域の市場成長を牽引しているのは、Novartis AG、Bristol Myers Squibb、Amgen Inc.、 AbbVieなどの主要プレイヤーの存在と、多発性骨髄腫(MM)治療薬の上市数、新製品承認数の増加です。例えば、2022年1月、Bristol-Myers Squibbは、B細胞成熟抗原(BCMA)指向性キメラ抗原受容体(CAR)T細胞免疫療法であるAbecma(idecabtagene vicleucel)を、再発または難治性(R/R)の多発性骨髄腫(MM)の成人患者の治療薬として厚生労働省が承認したと発表しました。さらに、2021年12月、Amgenは、米国食品医薬品局(FDA)が、1~3ライン治療を受けた再発または難治性の多発性骨髄腫(MM)の成人患者に対する治療として、KYPROLIS(carfilzomib)の米国処方情報に、DARZALEX FASPRO(R)(daratumumab・hyaluronidase-fihj)およびdexamethasoneとの併用療法を追加することを承認したと発表しました。
Global Multiple Myeloma Market Size, Share & Trends Analysis Report by Drug Class (Immunomodulators, Proteasome Inhibitors, Anti-CD38 Monoclonal Antibody, Alkylating Agents, and Others), by Type (Hyperdiploid, and Non-Hyperdiploid or Hypodiploid), and by Distribution Channel (Hospital Pharmacies, Retail Pharmacies & Drug Stores, and Online Pharmacies) Forecast Period (2023-2030)
The global multiple myeloma market is anticipated to grow at a considerable CAGR of 4.8% during the forecast period. The growth of the market is attributed to factors such as the increasing prevalence of multiple myeloma and advancements in diagnostic and treatment technologies. For instance, according to the University of California, in 2020, nearly 176,404 or 95% new cases of multiple myeloma were reported globally. Moreover, according to the Canadian Cancer Society, the number of new myeloma cases diagnosed in 2022 was 4,000, among them 2,400 males and 1,550 females, and nearly 11 people are diagnosed with myeloma each day. However, due to the introduction of newly developed targeted therapies and transplantation techniques, the rate of multiple myeloma get reduced. For instance, in February 2023, investigators at Memorial Sloan Kettering Cancer Center (MSK) published results from a clinical trial that found people with recurrent multiple myeloma get benefited from receiving chimeric antigen receptor (CAR) T therapy earlier in the course of their disease. With this therapy there was a nearly sevenfold increase in complete remission rates, and no cancer was detected in the body after the treatment.
The global multiple myeloma market is segmented based on its drug class, type, and distribution channel. Based on the drug class, the market is sub-segmented into immunomodulators, proteasome inhibitor, anti-CD38 monoclonal antibody, alkylating agents, and others. Based on its type, the market is bifurcated into hyperdiploid (HMM) and non-hyperdiploid or hypodiploid. Further, based on the distribution channel, the market is segmented into hospital pharmacies, retail pharmacies & drug stores, and online pharmacies. Among the distribution channel, the hospital sub-segment is projected to exhibit the highest growth, owing to the availability of trained medical staff in hospitals that provide better services to patients along with an increase in patient admission in hospitals.
Among the type segment, the hyperdiploid (HMM) sub-segment is anticipated to register significant growth for the forecast period. The growth of the HMM sub-segment is attributed to factors such as increasing R&D activities and rising demand for personalized medicine. For instance, in 2021, Janssen Biotech, Inc. announced the US FDA approval for DARZALEX FASPRO (daratumumab and hyaluronidase-fihj) for the treatment of patients with newly diagnosed or relapsed/refractory multiple myeloma.
The global multiple myeloma market is further segmented based on geography, including North America (the US and Canada), Europe (Italy, Spain, Germany, France, and Others), Asia-Pacific (India, China, Japan, South Korea, and Others), and the Rest of the World (the Middle East & Africa and Latin America). The market can be analyzed for a particular region or country level as per the requirement. Among these, North America is anticipated to grow at a significant CAGR over the forecast period. The growth is attributed to a rise in number of government funding organizations for R&D of cancer and increase in prevalence of multiple myeloma.
Global Multiple Myeloma Market Growth, by Region 2023-2030
Source: OMR Analysis
The growth of the market in the region is driven by the presence of key players such as Novartis AG, Bristol Myers Squibb, Amgen Inc., AbbVie, and others, coupled with an increase in the number of product launches, and new product approvals for multiple myeloma drugs. For instance, in January 2022, Bristol-Myers Squibb announced that Japan's Ministry of Health, Labor and Welfare approved Abecma (idecabtagene vicleucel), a B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T cell immunotherapy, for the treatment of adult patients with relapsed or refractory (R/R) multiple myeloma. Moreover, in December 2021, Amgen announced that the US Food and Drug Administration (FDA) approved the expansion of the KYPROLIS (carfilzomib) US prescribing information to include its use in combination with DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) and dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma who have received one to three lines of therapy.
The major companies serving the global multiple myeloma market include: Abbott Laboratories, Amgen Inc., GlaxoSmithKline plc, Merck & Co., Novartis AG, and others. The market players are considerably contributing to the market growth by the adoption of various strategies, including mergers and acquisitions, partnerships, collaborations, funding, and new product launches, to stay competitive in the market. For instance, in June 2021, AbbVie acquired the TeneoOne and its key immunotherapeutic asset for treating multiple myeloma named TNB-383B. TNB-383B is a bispecific antibody that targets both BCMA and CD3 and is designed to direct the body's own immune system to target and kill BCMA-expressing tumor cells. Through this partnership, both companies aim to develop and commercialize TNB-383B, a bispecific antibody that targets both BCMA and CD3 and is designed to direct the body's immune system to target and kill BCMA-expressing tumor cells.
The Report Covers: