HLAタイピングの世界市場の評価：製品・サービス別、技術別、用途別、エンドユーザー別、地域別、機会、予測（2017年～2031年）

世界のHLAタイピングの市場規模は、2023年の13億1,000万米ドルから2031年に21億3,000万米ドルに達すると予測され、予測期間の2024年～2031年にCAGRで6.27％の成長が見込まれます。市場の成長は、臓器移植の必要性の高まり、遺伝性疾患の症例の増加、研究活動への注目の高まり、市場の主要企業による新製品の発売などに支えられています。

Health Resource and Services Administration（HRSA）の推計によると、米国では約10万3,223人の男女と子供が全国移植待機リストに載っています。この増加により、臓器移植の症例が増加し、HLAタイピングの必要性が高まっています。世界のHLAタイピングの市場規模は、遺伝性疾患や自己免疫疾患の負担の増加に伴う研究活動の高まりにより増加しています。American Autoimmuneの推計によると、約5,000万人のアメリカ人が1つ以上の自己免疫疾患を抱えて生活しています。

市場の主要企業による新しい技術、製品、ソフトウェアの開発は、市場に有利な成長機会をもたらしています。2024年6月、Thermo Fisher Scientific Inc.は、臨床研究における正確な血液のジェノタイピングに向けたApplied Biosystems Axiom BloodGenomiX Arrayとソフトウェアを発表しました。この新しいアレイは、1回のアッセイで血小板型、希少血液型、組織を検出することができ、拡張表現型ドナー血液適合の進歩に寄与します。DNAベースの血液型検査の利用が増加することで、大規模なゲノム研究が支援され、輸血の有効性と安全性を向上させるための国際基準が導入されることが期待されます。スケーラブルなアレイベースの血液型検査ソリューションへのアクセスが増加することで、正確な適合に向けてさまざまな血液型を効果的にスクリーニングできるようになると予測されます。

HLAタイピングの技術の進歩が市場拡大を支える

市場の主要企業やさまざまな研究機関が先進技術の開発に向けた取り組みを強化していることから、今後数年間に市場に有利な成長機会がもたらされると予測されます。PacBioやIlluminaを含む次世代シーケンシング（NGS）技術は、非コード領域とコード領域を含むHLA遺伝子全体のシーケンシングを可能にするため、HLAタイピングに革命をもたらしました。

2023年11月、F. Hoffmann-La Roche Ltdは、公衆衛生の課題に取り組み、個別化医療を推進する次世代qPCRシステムを発売しました。LightCycler PRO Systemは、診断とトランスレーショナルリサーチに柔軟性と俊敏性を提供することで、発生への即応性をもたらすと予測されています。さらに2023年4月、Metropolis Healthcare Limitedは、HLA遺伝子を解析することにより、臓器移植、臍帯血、骨髄に適したドナーを特定するNextGen HLAタイピング検査を開始しました。NextGen HLAタイピング検査は、レシピエントとドナーのHLA適合率が高い移植を確実に行う上で、医師や患者を支援し、移植成功の可能性を高めると予測されています。

臓器移植の増加がHLAタイピング市場の成長を後押し

提供される臓器の増加による臓器移植の増加は、世界のHLAタイピング市場の需要を高める主な要因の1つです。Organ Procurement and Transplantation Network（OPTN）によると、2023年に米国で死亡時に1つ以上の臓器を提供した人は約1万6,335人で、2022年から9.6%増加しました。臓器提供の増加は、臓器提供の処置と提供者の健康に対する影響に関する意識の高まりによるものと考えられます。このことは、HLAマッチングが移植後の合併症に関連するリスクを軽減し、健康な新しい血液細胞の発達と成長を促進することから、その要求を促進します。ドナーとレシピエントは、少なくとも6つのHLAマーカーが一致する必要があります。不一致が多いと、患者の免疫システムから抗体が産生され、移植片を攻撃する可能性が高まるからです。

当レポートでは、世界のHLAタイピング市場について調査分析し、市場規模と予測、各地域の市場見通し、市場力学、競合情勢などを提供しています。

目次

第1章 プロジェクトの範囲と定義

第2章 調査手法

第3章 エグゼクティブサマリー

第4章 世界のHLAタイピング市場の見通し（2017年～2031年）

• 市場規模の分析と予測
  • 金額
  • 数量
• 市場シェア分析と予測
  • 製品・サービス別
  • 技術別
  • 用途別
  • エンドユーザー別
  • 地域別
  • 市場シェア分析：企業別（金額）（上位5社とその他 - 2023年）
• 市場マップ分析（2023年）
  • 製品・サービス別
  • 技術別
  • 用途別
  • エンドユーザー別
  • 地域別

第5章 北米のHLAタイピング市場の見通し（2017年～2031年）

• 市場規模の分析と予測
  • 金額
  • 数量
• 市場シェア分析と予測
  • 製品・サービス別
  • 技術別
  • 用途別
  • エンドユーザー別
  • シェア：国別
• 市場の評価：国別
  • 米国のHLAタイピング市場の見通し、2017年～2031年予測
  • カナダ
  • メキシコ

第6章 欧州のHLAタイピング市場の見通し（2017年～2031年）

• ドイツ
• フランス
• イタリア
• 英国
• ロシア
• オランダ
• スペイン
• ポーランド

第7章 アジア太平洋のHLAタイピング市場の見通し（2017年～2031年）

• インド
• 中国
• 日本
• オーストラリア
• ベトナム
• 韓国
• インドネシア
• フィリピン

第8章 南米のHLAタイピング市場の見通し（2017年～2031年）

• ブラジル
• アルゼンチン

第9章 中東・アフリカのHLAタイピング市場の見通し（2017年～2031年）

• サウジアラビア
• アラブ首長国連邦
• 南アフリカ
• イスラエル

第10章 需給分析

第11章 輸入と輸出の分析

第12章 バリューチェーン分析

第13章 ポーターのファイブフォース分析

第14章 PESTLE分析

第15章 価格分析

第16章 市場力学

• 市場促進要因
• 市場の課題

第17章 市場の動向と発展

第18章 規制枠組みとイノベーション

• 臨床試験
• 規制当局の承認

第19章 特許情勢

第20章 ケーススタディ

第21章 競合情勢

• マーケットリーダー上位5社の競合マトリクス
• 上位5社のSWOT分析
• 主要企業上位10社の情勢
  • Thermo Fisher Scientific Inc.
  • Bio-Rad Laboratories, Inc.
  • QIAGEN N.V.
  • F. Hoffmann-La Roche Ltd
  • bioMerieux SA
  • Illumina, Inc.
  • Becton, Dickinson and Company
  • Omixon Inc.
  • Takara Bio Inc.
  • TBG Diagnostics Limited

第22章 戦略的推奨

第23章 当社について、免責事項

List of Tables

• Table 1. Pricing Analysis of Products from Key Players
• Table 2. Competition Matrix of Top 5 Market Leaders
• Table 3. Mergers & Acquisitions/ Joint Ventures (If Applicable)
• Table 4. About Us - Regions and Countries Where We Have Executed Client Projects

List of Figures

• Figure 1. Global HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 2. Global HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 3. Global HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 4. Global HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 5. Global HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 6. Global HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 7. Global HLA Typing Market Share (%), By Region, 2017-2031F
• Figure 8. North America HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 9. North America HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 10. North America HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 11. North America HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 12. North America HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 13. North America HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 14. North America HLA Typing Market Share (%), By Country, 2017-2031F
• Figure 15. United States HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 16. United States HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 17. United States HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 18. United States HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 19. United States HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 20. United States HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 21. Canada HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 22. Canada HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 23. Canada HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 24. Canada HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 25. Canada HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 26. Canada HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 27. Mexico HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 28. Mexico HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 29. Mexico HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 30. Mexico HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 31. Mexico HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 32. Mexico HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 33. Europe HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 34. Europe HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 35. Europe HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 36. Europe HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 37. Europe HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 38. Europe HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 39. Europe HLA Typing Market Share (%), By Country, 2017-2031F
• Figure 40. Germany HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 41. Germany HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 42. Germany HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 43. Germany HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 44. Germany HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 45. Germany HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 46. France HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 47. France HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 48. France HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 49. France HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 50. France HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 51. France HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 52. Italy HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 53. Italy HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 54. Italy HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 55. Italy HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 56. Italy HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 57. Italy HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 58. United Kingdom HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 59. United Kingdom HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 60. United Kingdom HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 61. United Kingdom HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 62. United Kingdom HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 63. United Kingdom HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 64. Russia HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 65. Russia HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 66. Russia HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 67. Russia HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 68. Russia HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 69. Russia HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 70. Netherlands HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 71. Netherlands HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 72. Netherlands HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 73. Netherlands HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 74. Netherlands HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 75. Netherlands HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 76. Spain HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 77. Spain HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 78. Spain HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 79. Spain HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 80. Spain HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 81. Spain HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 82. Turkey HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 83. Turkey HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 84. Turkey HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 85. Turkey HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 86. Turkey HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 87. Turkey HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 88. Poland HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 89. Poland HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 90. Poland HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 91. Poland HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 92. Poland HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 93. Poland HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 94. South America HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 95. South America HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 96. South America HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 97. South America HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 98. South America HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 99. South America HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 100. South America HLA Typing Market Share (%), By Country, 2017-2031F
• Figure 101. Brazil HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 102. Brazil HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 103. Brazil HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 104. Brazil HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 105. Brazil HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 106. Brazil HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 107. Argentina HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 108. Argentina HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 109. Argentina HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 110. Argentina HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 111. Argentina HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 112. Argentina HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 113. Asia-Pacific HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 114. Asia-Pacific HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 115. Asia-Pacific HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 116. Asia-Pacific HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 117. Asia-Pacific HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 118. Asia-Pacific HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 119. Asia-Pacific HLA Typing Market Share (%), By Country, 2017-2031F
• Figure 120. India HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 121. India HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 122. India HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 123. India HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 124. India HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 125. India HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 126. China HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 127. China HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 128. China HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 129. China HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 130. China HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 131. China HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 132. Japan HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 133. Japan HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 134. Japan HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 135. Japan HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 136. Japan HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 137. Japan HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 138. Australia HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 139. Australia HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 140. Australia HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 141. Australia HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 142. Australia HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 143. Australia HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 144. Vietnam HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 145. Vietnam HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 146. Vietnam HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 147. Vietnam HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 148. Vietnam HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 149. Vietnam HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 150. South Korea HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 151. South Korea HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 152. South Korea HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 153. South Korea HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 154. South Korea HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 155. South Korea HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 156. Indonesia HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 157. Indonesia HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 158. Indonesia HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 159. Indonesia HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 160. Indonesia HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 161. Indonesia HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 162. Philippines HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 163. Philippines HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 164. Philippines HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 165. Philippines HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 166. Philippines HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 167. Philippines HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 168. Middle East & Africa HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 169. Middle East & Africa HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 170. Middle East & Africa HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 171. Middle East & Africa HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 172. Middle East & Africa HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 173. Middle East & Africa HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 174. Middle East & Africa HLA Typing Market Share (%), By Country, 2017-2031F
• Figure 175. Saudi Arabia HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 176. Saudi Arabia HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 177. Saudi Arabia HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 178. Saudi Arabia HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 179. Saudi Arabia HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 180. Saudi Arabia HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 181. UAE HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 182. UAE HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 183. UAE HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 184. UAE HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 185. UAE HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 186. UAE HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 187. South Africa HLA Typing Market, By Value, In USD Billion, 2017-2031F
• Figure 188. South Africa HLA Typing Market, By Volume, In Million Units, 2017-2031F
• Figure 189. South Africa HLA Typing Market Share (%), By Products and Services, 2017-2031F
• Figure 190. South Africa HLA Typing Market Share (%), By Technology, 2017-2031F
• Figure 191. South Africa HLA Typing Market Share (%), By Application, 2017-2031F
• Figure 192. South Africa HLA Typing Market Share (%), By End-user, 2017-2031F
• Figure 193. By Products and Services Map-Market Size (USD Billion) & Growth Rate (%), 2023
• Figure 194. By Technology Map-Market Size (USD Billion) & Growth Rate (%), 2023
• Figure 195. By Application Map-Market Size (USD Billion) & Growth Rate (%), 2023
• Figure 196. By End-user Map-Market Size (USD Billion) & Growth Rate (%), 2023
• Figure 197. By Region Map-Market Size (USD Billion) & Growth Rate (%), 2023

Global HLA typing market is projected to witness a CAGR of 6.27% during the forecast period 2024-2031, growing from USD 1.31 billion in 2023 to USD 2.13 billion in 2031. The market's growth is supported by the rising requirement for organ transplantation, increasing cases of genetic diseases, growing emphasis on research activities, and novel product launches by the leading players of the market.

According to the estimates of the Health Resource and Services Administration (HRSA) approximately 103,223 men, women, and children are on the national transplant waiting list in the United States. Due to this increase, the cases of organ transplant procedures are rising, bolstering the requirement for HLA typing. The global HLA typing market size is increasing due to the rising research activities on genetic and autoimmune diseases due to their growing burden. According to the estimates of the American Autoimmune, approximately 50 million Americans are living with one or more autoimmune diseases.

The development of novel technologies, products, and software by the leading players in the market is providing lucrative growth opportunities to the market. In June 2024, Thermo Fisher Scientific Inc. introduced their Applied Biosystems Axiom BloodGenomiX Array and software for precise blood genotyping in clinical research. The new array is capable of detecting platelet types, rare blood groups, and tissues in a single assay, aiding advancements in extended phenotype donor blood matching. Increasing utilization of DNA-based blood typing is expected to support large-scale genomics research and the introduction of international standards for improving the efficacy and safety of blood transfusion. The increasing accessibility of scalable array-based blood typing solutions is expected to effectively screen various blood types for precise matching.

Technological Advancements in HLA Typing Support the Market Expansion

The increasing efforts of the key players of the market and various research institutions toward the development of advanced technologies are expected to provide lucrative growth opportunities to the market in the forecast years. Next-generation sequencing (NGS) technologies, including PacBio and Illumina, have revolutionized HLA typing as they enable the sequencing of entire HLA genes, including noncoding and coding regions.

In November 2023, F. Hoffmann-La Roche Ltd launched a next-generation qPCR system to address public health challenges and advance personalized healthcare. The LightCycler PRO System is expected to provide outbreak readiness by providing flexibility and agility for diagnostics and translational research. Additionally, in April 2023, Metropolis Healthcare Limited launched their NextGen HLA typing test for identifying suitable donors for organ transplantation, cord blood, and bone marrow by analyzing the HLA gene. The NextGen HLA typing test is expected to aid physicians, doctors, and patients in ensuring transplants at a higher HLA match percentage between the recipient and the donor, bolstering the chances of successful transplants.

Increasing Organ Transplantation Boosts HLA Typing Market Growth

The rise in organ transplant procedures due to the increasing availability of donated organs is one of the major factors bolstering the global HLA typing market demand. According to the Organ Procurement and Transplantation Network (OPTN), in 2023, approximately 16,335 individuals donated one or more organs upon their death in the United States, showcasing a 9.6% increase from 2022. The increasing donations can be attributed to the growing awareness about the procedure and the impact of the donation on donor health. This propels the requirement for HLA matching as it reduces the risks associated with post-transplant complications and promotes the development and growth of healthy new blood cells. Donors and recipients should have a match of at least 6 HLA markers, as a high degree of mismatch augments the chances of antibody production from the immune system of the patient, which can attack the graft.

Diagnostics Segment Expected to Witness Significant Growth

The growth of the segment is supported by the rising requirement for organ transplantation and increasing cases of autoimmune and genetic diseases. For instance, the HLA-B27 test is conducted to confirm or dismiss suspected cases of ankylosing spondylitis (AS), juvenile rheumatoid arthritis, and reactive arthritis. The test aids healthcare professionals in determining the presence or absence of the HLA-B27 protein on the surface of the white blood cells in individuals. Additionally, the expansion of the segment is supported by the rising collaborations between different diagnostic and biotech companies to support the development of HLA typing kits. In November 2023, OSE Immunotherapeutics and GenDx announced the partnership for developing NGSengine software and NGSgo HLA-A typing kit as a companion diagnostic (CDx) for cancer vaccines. With the partnership, the companies aim to validate and develop a CDx test for epitope-based cancer vaccines to improve the survival and the quality of patients' lives.

North America Holds Significant Market Share

The presence of leading market players, rising requirements for organ transplantation in the region, novel product launches, and presence of well-established healthcare infrastructure are some of the major factors boosting the market's growth. According to estimates from the United Network for Organ Sharing (UNOS), in 2023 over 46,000 organ transplants were performed in the United States. This increase propels the market demand as HLA typing is one of the essential components for matching hematopoietic cells between the recipients and the donors for improving patient outcomes by aiding patients in avoiding graft-versus-host disease (GVHD) and acute graft rejection.

The strong presence of various research institutions and increasing investments in research activities are another significant factors supporting the market's expansion. For instance, the Memorial Sloan Kettering Cancer Center is conducting an interventional study to evaluate if the addition of specific genetic factors to the process of selecting a stem cell donor reduces the chances of leukemia coming back in patients after the bone marrow has been transplanted. The study is expected to conclude in May 2025 and aims to demonstrate that patients with adult acute myeloid leukemia (AML) who have donors with specific HLA and killer immunoglobulin-like receptors (KIR) genes have better outcomes.

Future Market Scenario (2024 - 2031F)

Market demand is expected to increase significantly over the forecast period due to the rise in the number of organ transplantations. Advancements in bioinformatics and nanopore technology are expected to enhance the efficiency, speed, and reliability of HLA genotyping, revolutionizing their clinical applications and immunogenetics.

The increasing autoimmune diseases incidences are bolstering the requirement for HLA typing, as it can provide insights about various risks of autoimmune diseases and guide the development of prophylactic interventions for reducing the risks in individuals that are susceptible to the disease.

The growing efforts of the key market players towards the development of novel technologies and products is another major factor expected to boost the growth of the market in the coming years.

Key Players Landscape and Outlook

The rising efforts of the key players of the market towards the development of novel products and technologies and increasing receival of approvals from various regulatory bodies are supporting the global HLA typing market growth. These efforts and approvals aid healthcare professionals in accurately diagnosing various diseases and disorders and support the introduction of new products to meet the evolving requirements of the healthcare industry.

In December 2022, Thermo Fisher Scientific Inc. announced that they received De Novo Classification from the US Food and Drug Administration (FDA) for their SeCore CDx HLA Sequencing System, the system allows clinicians to identify patients that will benefit from this immunotherapy breakthrough. The company plans on partnering with leading companies for commercializing and developing immunotherapies for meeting the unmet requirements of patients for a wide range of diseases.

Table of Contents

1. Project Scope and Definitions

2. Research Methodology

3. Executive Summary

4. Global HLA Typing Market Outlook, 2017-2031F

• 4.1. Market Size Analysis & Forecast
  • 4.1.1. By Value
  • 4.1.2. By Volume
• 4.2. Market Share Analysis & Forecast
  • 4.2.1. By Products and Services
    • 4.2.1.1. Instruments
    • 4.2.1.2. Reagents and Consumables
    • 4.2.1.3. Software and Services
  • 4.2.2. By Technology
    • 4.2.2.1. Molecular Assays
      • 4.2.2.1.1. Sequencing-based Molecular Assays
        • 4.2.2.1.1.1. Sanger Sequencing
        • 4.2.2.1.1.2. Next-generation Sequencing
        • 4.2.2.1.1.3. Pyrosequencing
      • 4.2.2.1.2. PCR-based Molecular Assays
        • 4.2.2.1.2.1. Sequence-specific Primer-PCR
        • 4.2.2.1.2.2. Sequence-specific Oligonucleotide-PCR
        • 4.2.2.1.2.3. Others
    • 4.2.2.2. Non-molecular Assays
  • 4.2.3. By Application
    • 4.2.3.1. Diagnostics
      • 4.2.3.1.1. Infectious Diseases Diagnostics
      • 4.2.3.1.2. Cancer Diagnosis and Prevention
      • 4.2.3.1.3. Transmission Therapy
      • 4.2.3.1.4. Donor Recipient Cross-Matching
    • 4.2.3.2. Research
  • 4.2.4. By End-user
    • 4.2.4.1. Hospitals and Transplant Centers
    • 4.2.4.2. Commercial Service Providers
    • 4.2.4.3. Research Labs and Academic Institutes
  • 4.2.5. By Region
    • 4.2.5.1. North America
    • 4.2.5.2. Europe
    • 4.2.5.3. Asia-Pacific
    • 4.2.5.4. South America
    • 4.2.5.5. Middle East and Africa
  • 4.2.6. By Company Market Share Analysis (Top 5 Companies and Others - By Value, 2023)
• 4.3. Market Map Analysis, 2023
  • 4.3.1. By Products and Services
  • 4.3.2. By Technology
  • 4.3.3. By Application
  • 4.3.4. By End-user
  • 4.3.5. By Region

5. North America HLA Typing Market Outlook, 2017-2031F*

• 5.1. Market Size Analysis & Forecast
  • 5.1.1. By Value
  • 5.1.2. By Volume
• 5.2. Market Share Analysis & Forecast
  • 5.2.1. By Products and Services
    • 5.2.1.1. Instruments
    • 5.2.1.2. Reagents and Consumables
    • 5.2.1.3. Software and Services
  • 5.2.2. By Technology
    • 5.2.2.1. Molecular Assays
      • 5.2.2.1.1. Sequencing-based Molecular Assays
        • 5.2.2.1.1.1. Sanger Sequencing
        • 5.2.2.1.1.2. Next-generation Sequencing
        • 5.2.2.1.1.3. Pyrosequencing
      • 5.2.2.1.2. PCR-based Molecular Assays
        • 5.2.2.1.2.1. Sequence-specific Primer-PCR
        • 5.2.2.1.2.2. Sequence-specific Oligonucleotide-PCR
        • 5.2.2.1.2.3. Others
    • 5.2.2.2. Non-molecular Assays
  • 5.2.3. By Application
    • 5.2.3.1. Diagnostics
      • 5.2.3.1.1. Infectious Diseases Diagnostics
      • 5.2.3.1.2. Cancer Diagnosis and Prevention
      • 5.2.3.1.3. Transmission Therapy
      • 5.2.3.1.4. Donor Recipient Cross-Matching
    • 5.2.3.2. Research
  • 5.2.4. By End-user
    • 5.2.4.1. Hospitals and Transplant Centers
    • 5.2.4.2. Commercial Service Providers
    • 5.2.4.3. Research Labs and Academic Institutes
  • 5.2.5. By Country Share
    • 5.2.5.1. United States
    • 5.2.5.2. Canada
    • 5.2.5.3. Mexico
• 5.3. Country Market Assessment
  • 5.3.1. United States HLA Typing Market Outlook, 2017-2031F*
    • 5.3.1.1. Market Size Analysis & Forecast
      • 5.3.1.1.1. By Value
      • 5.3.1.1.2. By Volume
    • 5.3.1.2. Market Share Analysis & Forecast
      • 5.3.1.2.1. By Products and Services
        • 5.3.1.2.1.1. Instruments
        • 5.3.1.2.1.2. Reagents and Consumables
        • 5.3.1.2.1.3. Software and Services
      • 5.3.1.2.2. By Technology
        • 5.3.1.2.2.1. Molecular Assays
        • 5.3.1.2.2.1.1. Sequencing-based Molecular Assays
        • 5.3.1.2.2.1.1.1. Sanger Sequencing
        • 5.3.1.2.2.1.1.2. Next-generation Sequencing
        • 5.3.1.2.2.1.1.3. Pyrosequencing
        • 5.3.1.2.2.1.2. PCR-based Molecular Assays
        • 5.3.1.2.2.1.2.1. Sequence-specific Primer-PCR
        • 5.3.1.2.2.1.2.2. Sequence-specific Oligonucleotide-PCR
        • 5.3.1.2.2.1.2.3. Others
        • 5.3.1.2.2.2. Non-molecular Assays
      • 5.3.1.2.3. By Application
        • 5.3.1.2.3.1. Diagnostics
        • 5.3.1.2.3.1.1. Infectious Diseases Diagnostics
        • 5.3.1.2.3.1.2. Cancer Diagnosis and Prevention
        • 5.3.1.2.3.1.3. Transmission Therapy
        • 5.3.1.2.3.1.4. Donor Recipient Cross-Matching
        • 5.3.1.2.3.2. Research
      • 5.3.1.2.4. By End-user
        • 5.3.1.2.4.1. Hospitals and Transplant Centers
        • 5.3.1.2.4.2. Commercial Service Providers
        • 5.3.1.2.4.3. Research Labs and Academic Institutes
  • 5.3.2. Canada
  • 5.3.3. Mexico

All segments will be provided for all regions and countries covered

6. Europe HLA Typing Market Outlook, 2017-2031F

• 6.1. Germany
• 6.2. France
• 6.3. Italy
• 6.4. United Kingdom
• 6.5. Russia
• 6.6. Netherlands
• 6.7. Spain
• 6.8. Poland

7. Asia-Pacific HLA Typing Market Outlook, 2017-2031F

• 7.1. India
• 7.2. China
• 7.3. Japan
• 7.4. Australia
• 7.5. Vietnam
• 7.6. South Korea
• 7.7. Indonesia
• 7.8. Philippines

8. South America HLA Typing Market Outlook, 2017-2031F

• 8.1. Brazil
• 8.2. Argentina

9. Middle East and Africa HLA Typing Market Outlook, 2017-2031F

• 9.1. Saudi Arabia
• 9.2. UAE
• 9.3. South Africa
• 9.4. Israel

10. Demand Supply Analysis

11. Import and Export Analysis

12. Value Chain Analysis

13. Porter's Five Forces Analysis

14. PESTLE Analysis

15. Pricing Analysis

16. Market Dynamics

• 16.1. Market Drivers
• 16.2. Market Challenges

17. Market Trends and Developments

18. Regulatory Framework and Innovation

• 18.1. Clinical Trials
• 18.2. Regulatory Approvals

19. Patent Landscape

20. Case Studies

21. Competitive Landscape

• 21.1. Competition Matrix of Top 5 Market Leaders
• 21.2. SWOT Analysis for Top 5 Players
• 21.3. Key Players Landscape for Top 10 Market Players
  • 21.3.1. Thermo Fisher Scientific Inc.
    • 21.3.1.1. Company Details
    • 21.3.1.2. Key Management Personnel
    • 21.3.1.3. Products and Services
    • 21.3.1.4. Financials (As Reported)
    • 21.3.1.5. Key Market Focus and Geographical Presence
    • 21.3.1.6. Recent Developments/Collaborations/Partnerships/Mergers and Acquisition
  • 21.3.2. Bio-Rad Laboratories, Inc.
  • 21.3.3. QIAGEN N.V.
  • 21.3.4. F. Hoffmann-La Roche Ltd
  • 21.3.5. bioMerieux SA
  • 21.3.6. Illumina, Inc.
  • 21.3.7. Becton, Dickinson and Company
  • 21.3.8. Omixon Inc.
  • 21.3.9. Takara Bio Inc.
  • 21.3.10. TBG Diagnostics Limited

Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.

22. Strategic Recommendations

23. About Us and Disclaimer