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市場調査レポート
商品コード
1447728
慢性蕁麻疹市場の評価:治療法・診断・投与経路・エンドユーザー・地域別の機会および予測 (2017~2031年)Chronic Spontaneous Urticaria Market Assessment, By Treatment, By Diagnosis, By Route of Administration, By End-user, By Region, Opportunities and Forecast, 2017-2031F |
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カスタマイズ可能
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慢性蕁麻疹市場の評価:治療法・診断・投与経路・エンドユーザー・地域別の機会および予測 (2017~2031年) |
出版日: 2024年03月11日
発行: Market Xcel - Markets and Data
ページ情報: 英文 225 Pages
納期: 3~5営業日
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世界の慢性蕁麻疹の市場規模は、2023年の20億1,000万米ドルから、2024年から2031年の予測期間中は11.93%のCAGRで推移し、2031年には49億5,000万米ドルの規模に成長すると予測されています。
慢性蕁麻疹の有病率の増加、R&Dへの多額の投資、治療に適した薬剤の入手可能性、皮下注射薬の臨床的優位性、臨床試験の増加など、さまざまな要因が世界の慢性蕁麻疹市場を形成しています。慢性蕁麻疹の世界市場は、画期的な発見や病気に対する理解の深まりにより大きく拡大しています。
蕁麻疹の基本的なメカニズムの徹底的な解明により、より強力な治療薬が生み出されつつあります。製薬会社や医療提供者からのR&D資金の増加により、新たな治療法が発見され、市場に導入されています。慢性蕁麻疹の病態生理に関する知識の向上は、従来のアプローチよりも優れた症状緩和をもたらす、より効果的なテーラーメード医薬品の開発につながっています。世界の慢性蕁麻疹市場は、薬剤の皮下投与が可能になったことも影響しています。この方法は、患者の末梢系に影響を与えることなく薬剤を完全に吸収でき、血管や神経を傷つける可能性もないため、非常に効果的です。
Novartisは2023年8月、慢性蕁麻疹患者を対象としたBTK阻害剤レミブルチニブ25mg b.i.d.を評価する第III相REMIX-1およびREMIX-2試験の良好なトップラインデータを報告しました。レミブルチニブが承認されれば、慢性蕁麻疹を治療する10年ぶりの薬剤となる可能性があり、H1-抗ヒスタミン薬が無効な患者の60%に、簡便で効率的な代替薬を提供することになります。
R&D促進のための多額の投資
世界の慢性蕁麻疹市場の成長は、製薬企業によるR&D活動への絶え間ない注力によっても牽引されています。市場の主要企業は、慢性蕁麻疹の患者を治療するための革新的な解決策を見出すための研究活動に巨額を投じています。研究を通じて、企業は本疾患の治療を取り巻く要因についてさまざまな洞察を得ることができます。
医療インフラ改善のための多額の投資
効率的な慢性蕁麻疹治療に対するニーズが高まっていることを受け、世界の慢性蕁麻疹市場の主要企業は、投資を通じて医療インフラの改善に向けた取り組みを強化しています。このような計算された行動は、慢性蕁麻疹の発症率の上昇を動機としています。慢性蕁麻疹は、突然発症し、明確な理由がない腫れや蕁麻疹を特徴とする疾患です。これらの企業は、医療インフラにより多くの資金を投入することで、より強力で新しい治療法を生み出し、提供することを望んでいます。慢性蕁麻疹患者のアンメットニーズを満たすための献身を示すだけでなく、この投資は、より良い治療が患者の良好な転帰をもたらし、最先端の治療に対する需要が高まることにより、市場が大きく発展する可能性があることを示しています。
当レポートでは、世界の慢性蕁麻疹の市場を調査し、市場の定義と概要、市場規模の推移・予測、各種区分・地域別の詳細分析、産業構造、市場成長への影響因子の分析、ケーススタディ、競合情勢、主要企業のプロファイルなどをまとめています。
The chronic spontaneous urticaria market is projected to witness a CAGR of 11.93% during the forecast period 2024-2031, growing from USD 2.01 billion in 2023 to USD 4.95 billion in 2031. Various factors are shaping the global chronic spontaneous urticaria market such as the increasing prevalence of chronic spontaneous urticaria, significant investments in research and development, availability of suitable medications for treatment, clinical advantages of subcutaneous drugs, and increasing number of clinical trials. The global chronic spontaneous urticaria market, which is defined by recurring hives and angioedema without known triggers, is expanding significantly due to breakthrough discoveries and a better comprehension of the illness.
The creation of more potent treatments is being fueled by a more thorough investigation of the fundamental mechanisms of CSU. New therapeutic options are being discovered and introduced in the market through increased research and development funding from pharmaceutical companies and healthcare providers. Improved knowledge of the pathophysiology of CSU is leading to more effective tailored medicines that provide better symptom alleviation than conventional approaches. The global chronic spontaneous urticaria market is affected by the ability to administer medications subcutaneously. The method is highly effective as it allows complete absorption of the drug without affecting patient's peripheral system and no chances of injury to the vessels and nerves.
Novartis reported positive top-line data in August 2023 from the Phase III REMIX-1 and REMIX-2 studies assessing the BTK inhibitor remibrutinib 25 mg b.i.d. in patients with chronic spontaneous urticaria (CSU). Remibrutinib, if authorized, could be the first medication in a decade to treat chronic spontaneous urticaria (CSU), providing a straightforward and efficient alternative for 60% of patients for whom H1-antihistamines are ineffective.
Significant Investments for Expediting Research and Development
The growth of global chronic spontaneous urticaria market is being driven by a constant focus on research and development activities by pharmaceutical companies. Major companies in the market are spending huge amounts in conducting research activities to find innovative solutions for treating patients with CSU. Through research, companies can discover various insights into the factors revolving around the treatment of the disease. All these factors indicate that there is a strong association between the research efforts and the increasing growth trajectory of the global chronic spontaneous urticaria market. In January 2024, Enanta Pharmaceuticals, a clinical-stage biotechnology company, provided updates on its research and development programs and the outlook for the year 2024, at the 42nd Annual J.P. Morgan healthcare conference. The company announced its expansion into immunology and discovery programs to treat CSU.
Significant Investments for Improving Healthcare Infrastructure
Noticing the increasing need for efficient CSU therapies, major players in the global chronic spontaneous urticaria market are stepping up their efforts to improve healthcare infrastructure through investments. The calculated action is motivated by the rising incidence of CSU, a disorder marked by swelling and hives that develop suddenly and have no apparent reason. These businesses hope to create and offer novel, more potent treatment alternatives by investing more money in the healthcare infrastructure. In addition to demonstrating their dedication to meet the unmet needs of CSU patients, the investment shows the market has the potential to develop significantly due to better treatments resulting in favorable patient outcomes and a rise in demand for cutting-edge therapies.
Many companies in the global chronic spontaneous urticaria market are increasing their investments in the market. For instance, in April 2023, Evommune, Inc. announced the completion of USD 50 million Series B financing to develop new innovative technologies to treat inflammatory diseases such as CSU. Along with current investors EQT Life Sciences and SymBiosis, new investor Arix Bioscience led the funding.
Availability of Novel Medications for Treatment
The development and accessibility of therapeutic alternatives, such as immunosuppressants, biologic therapies, and antihistamines, are the main factors driving the global chronic spontaneous urticaria market. These medications are highly effective due to which their demand in the market is increasing drastically. Medical research advancements have led to the development of many such medications, with more under clinical trials. Second-line drugs like leukotriene receptor antagonists (like montelukast), oral corticosteroids (like prednisone), H2 blockers (like cimetidine), and biologics (like omalizumab; Xolair) may be prescribed to treat patients with refractory symptoms. In January 2024, Evommune, Inc., a clinical-stage biotechnology company, announced the beginning of its human study for Phase 1, to find out EVO756 in adults with CSU. If the trial turns out to be successful, then EVO756 can be the first oral treatment for several diseases such as CSU and inflammatory itch.
Clinical Advantages of Subcutaneous Drugs
Subcutaneous drugs absorb easily without any side effects. Subcutaneous drugs offer numerous clinical benefits such as patient convenience, reduced cost, fewer side effects, enhanced patient satisfaction, and improved drug absorption. With less frequent doses and consistent medication absorption, it can potentially minimize the need for hospital visits and increase patient compliance by enabling self-administration at home. Subcutaneous drugs are highly effective offering a reliable treatment for CSU. Home administration eliminates the need for expensive hospital visits and decreases the demand for medical personnel, resulting in lower healthcare expenses. Compared to intravenous administration, subcutaneous administration often leads to fewer adverse events, particularly those related to infusions, such as infections and hypersensitivity reactions.
On February 16, 2024, Genentech, a member of Roche Group, announced Xolair for the treatment of anaphylaxis and allergic reactions caused due to food allergies in children and adults. It received approval from the U.S. Food and Drug Administration (FDA) and has been cleared for use of treating CSU.
Asia-Pacific to Grow at the Fastest Rate During the Forecast Period
Several countries in Asia-Pacific are going to observe rapid growth in the global chronic spontaneous urticaria market. Economic growth in countries like China and India is going to play a major role in market expansion along with the countries such as China, Japan, India, Australia, and South Korea. The trend can be attributed to the region's increasing population growth, government initiatives, and improving healthcare infrastructure. People are becoming more aware of the illness and its implications, which increases the demand for effective therapies. Additionally, by giving patients more treatment options, the emergence of new pharmaceutical businesses in the market with a focus on cutting-edge CSU therapy promotes market expansion.
On 16 February 2024, Dupixent, a drug used for the treatment of CSU, jointly developed by Sanofi and Regeneron, was granted permission for manufacturing and marketing by the Ministry of Health, Labour and Welfare (MHLW) in Japan.
Future Market Scenario (2024 - 2031F)
To handle the complexity of CSU, businesses are actively seeking novel solutions. For example, Amalizumab, a monoclonal antibody that targets immunoglobulin E (IgE), was developed and is now authorized for use in CSU.
It is anticipated that the creation of novel diagnostic instruments and methodologies will enhance the precision and promptness of CSU diagnosis, resulting in improved patient outcomes. For instance, blood and skin prick tests can be used to determine the underlying cause of CSU, which enables doctors to adjust treatment regimens accordingly.
Advancement in treatment options like targeted therapies and biologics will lead to the expansion of the global spontaneous urticaria market.
Patients are more likely to receive access to cutting-edge CSU medicines and treatments as global healthcare spending rises.
Key Players Landscape and Outlook
The chronic spontaneous urticaria market is expected to experience significant growth in the coming years, driven by factors such as increasing prevalence of urticaria, rising healthcare spending, and technological advancements in medicine and digital health. The market is highly competitive, with key players including Roche, Novartis, Sanofi, AstraZeneca, and GlaxoSmithKline, and others. The global chronic spontaneous urticaria market is witnessing a significant shift towards strategic partnerships among leading companies in the industry. By working together, these organizations can overcome technical and clinical barriers that would otherwise prevent them from moving forward independently.
A Complete Response Letter (CRL) for the supplementary Biologics Licence Application for Dupixent was made available by the U.S. FDA in October 2023. A medication called Dupixent used to treat CSU, is being developed in collaboration with the American biotechnology company Regeneron and Sanofi.
All segments will be provided for all regions and countries covered
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.