市場調査レポート
商品コード
1417591
頭頸部がんの世界市場の評価:治療タイプ別、投与経路別、薬剤クラス別、販売チャネル別、地域別、機会、予測(2017年~2031年)Head and Neck Cancer Market Assessment, By Therapy Type By Route of Administration, By Drug Class, By Distribution Channel By Region, Opportunities and Forecast, 2017-2031F |
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頭頸部がんの世界市場の評価:治療タイプ別、投与経路別、薬剤クラス別、販売チャネル別、地域別、機会、予測(2017年~2031年) |
出版日: 2024年01月29日
発行: Market Xcel - Markets and Data
ページ情報: 英文 244 Pages
納期: 3~5営業日
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世界の頭頸部がんの市場規模は2023年に22億5,000万米ドル、2031年に37億6,000万米ドルに達し、2024年~2031年の予測期間にCAGRで6.62%の成長が見込まれています。疾患と治療法の理解が進むにつれて、市場は大きな成長と進化を示しています。
頭頸部がんは、口腔、咽頭、喉頭などに発生する腫瘍を含み、世界的に大きな医療負担となっています。タバコやアルコールの摂取、ヒトパピローマウイルス(HPV)感染、環境要因などの危険因子が、これらのがんの発症に寄与しています。世界の頭頸部がん市場は、罹患率の増加、診断方法の改善、革新的な治療アプローチの開発などの要因によって牽引されています。近年の免疫療法や標的療法の進歩は患者に希望をもたらしています。これらの新たな治療法は、精密医療や個別化治療計画への注目の高まりとともに、市場に変革をもたらしつつあります。市場の主要企業は、新たな治療法を導入し、製品ポートフォリオを拡大するために研究開発に投資しています。さらに、早期発見と予防の重要性に対する意識の高まりも、市場の成長に寄与しています。世界の頭頸部がん市場はダイナミックで急速に発展しており、先進の治療オプションと早期介入戦略を通じて患者の転帰を改善することに注力しています。
Elsevierが発表した記事によると、免疫療法の導入が頭頸部がんの治療に顕著な変革をもたらしたと報告されています。これらの治療法は、腫瘍細胞とTリンパ球の相互作用を媒介する免疫抑制経路を調節することに主眼が置かれています。2022年8月にFrontiersに発表された記事では、特に頭頸部扁平上皮がんの治療において、免疫療法が持続的な抗腫瘍効果をもたらす大きな可能性が示されています。共刺激アゴニスト、免疫チェックポイント阻害薬、抗原ワクチン、養子T細胞移植(ACT)、オンコリティックウイルス療法、EGFR標的療法などのさまざまな免疫療法アプローチが頭頸部扁平上皮がん(HNSCC)の治療に用いられています。例えば、Merckは2023年11月、FDAがMerckの抗PD-1療法であるキイトルーダを、ゲムシタビンとシスプラチンとともに、局所進行切除不能または転移性の胆道がん(BTC)向けの治療薬として承認したと発表しました。
近年、世界の頭頸部がんに関連する研究開発活動が急増しています。このような注目の高まりは複数の要因に起因しています。例えば、世界の頭頸部がんの罹患率の上昇により、予防、早期発見、治療戦略に関するより包括的な研究の必要性が高まっています。また、ゲノミクスや標的療法を含む医療技術の進歩により、個別化されたより効果的な治療への新たな道が開かれました。
例えば、臨床開発後期のバイオテクノロジー企業であるNanobiotixは、2023年10月、NBTXR3の安全性と有効性を検証するフェーズ3臨床試験であるNANORAY-312の患者登録開始を発表しました。この薬剤候補は、高齢者の頭頸部がんの効果的な治療において大きな可能性を示しています。2022年9月、免疫療法の開発とマーケティングに特化した臨床段階にあるバイオテクノロジー企業Genexine Inc.は、フェーズ2臨床試験の患者投与開始を発表しました。GX-188E(治療用DNAワクチン)、GX-I7(長時間作用型インターロイキン7)、OpdivoR(ニボルマブ)、PD-1免疫チェックポイント阻害薬を含む3剤併用療法を採用し、転移性または再発性の頭頸部扁平上皮がんに対処します。
当レポートでは、世界の頭頸部がん市場について調査分析し、市場規模と予測、市場力学、主要企業情勢と見通しなどを提供しています。
Global head and neck cancer market size was valued at USD 2.25 billion in 2023, and is expected to reach USD 3.76 billion in 2031, with a CAGR of 6.62% for the forecast period between 2024 and 2031F. The global head and neck cancer market encompasses a diverse range of treatments and therapies aimed at addressing the complex and challenging landscape of cancers that affect the head and neck regions. The market is experiencing significant growth and evolution as the understanding of the disease and its treatment options continue to advance.
Head and neck cancers, which include tumors in the oral cavity, pharynx, larynx, and other areas, represent a substantial global healthcare burden. Risk factors such as tobacco and alcohol consumption, human papillomavirus (HPV) infection, and environmental factors contribute to the development of these cancers. The global market for head and neck cancer is driven by factors such as increasing incidence rates, improved diagnostic methods, and the development of innovative therapeutic approaches. Recent advancements in immunotherapy and targeted therapies have brought hope to patients. These emerging treatment modalities, along with a growing focus on precision medicine and personalized treatment plans, are transforming the market. Key market players invest in research and development to introduce novel therapies and expand their product portfolios. Moreover, the increasing awareness about the importance of early detection and prevention contributes to market growth. The global head and neck cancer market is dynamic and rapidly evolving, focusing on improving patient outcomes through advanced treatment options and early intervention strategies.
As per an article published by Elsevier, it was reported that the introduction of immunotherapies has brought about a notable transformation in the treatment of head and neck cancer. These therapies are primarily focused on modulating the immunosuppressive pathways that mediate the interaction between tumor cells and T-lymphocytes. An article published in August 2022 by Frontiers highlighted the significant potential of immunotherapies to generate enduring antitumor effects, particularly in the context of treating head and neck squamous cell carcinomas. Various immunotherapy approaches, including the use of costimulatory agonists, immune checkpoint inhibitors, antigenic vaccines, adoptive T cell transfer (ACT), oncolytic virus therapy, and EGFR-targeted therapy, are now being employed for the management of head and neck squamous cell carcinomas (HNSCC). For Instance, Merck declared in November 2023 that the U.S. Food and Drug Administration (FDA) has given the green light to KEYTRUDA, Merck's anti-PD-1 therapy, along with gemcitabine and cisplatin, for addressing individuals dealing with locally advanced unresectable or metastatic biliary tract cancer (BTC).
In recent years, there has been a noticeable surge in research and development activities related to global head and neck cancer. The increased focus can be attributed to several factors, such as the rising incidence of head and neck cancer cases worldwide has spurred the need for more comprehensive research into prevention, early detection, and treatment strategies. Also, advancements in medical technologies, including genomics and targeted therapies, have opened new avenues for personalized and more effective treatments.
For instance, In October 2023, Nanobiotix, a biotechnology company in the later stages of clinical development, announced the initiation of patient enrollment for NANORAY-312, a phase III clinical trial to examine the safety and effectiveness of NBTXR3. The drug candidate has demonstrated significant promise in effectively treating head and neck cancer among elderly patients. In September 2022, Genexine Inc, a biotechnology company in the clinical stage focused on developing and marketing immunotherapies, announcing the initiation of patient dosing in a phase II clinical trial. The company employed a triple combination therapy involving GX-188E (a therapeutic DNA vaccine), GX-I7 (a long-acting interleukin 7), OpdivoR (nivolumab), and PD-1 immune checkpoint inhibitor, for addressing metastatic or recurrent head and neck squamous cell carcinoma.
In the dynamic landscape of global head and neck cancer market, strategic partnerships among key industry players have emerged as pivotal instruments for innovation and progress. These collaborations, characterized by shared expertise and resources, aim to advance research, develop cutting-edge therapies, and improve patient outcomes. Through such alliances, companies combine their strengths in drug development, medical technology, and clinical research to accelerate the discovery and delivery of novel treatments. These partnerships often foster synergies, allowing the pooling of knowledge, technologies, and financial resources. They facilitate the streamlining of regulatory processes and establishing wider access to global markets. Ultimately, these strategic alliances drive the evolution of more effective therapies, early detection methods, and personalized treatment solutions in the fight against head and neck cancers. The collective efforts of these collaborations hold promising potential for shaping the future of cancer care. For Instance, In November 2022, Fulgent Genetics, Inc., a technology-driven genetic testing company situated in the United States, revealed its acquisition of Fulgent Pharma Holdings, Inc. The acquisition aimed to offer a unified solution in the region's fight against head and neck cancer.
Key players in the global head and neck cancer therapeutics market have been strategically focused on several initiatives to enhance treatment outcomes and address unmet medical needs. These initiatives primarily revolve around innovative research and development efforts, collaborative partnerships, and technological advancements. Companies are heavily investing in novel therapies, including immunotherapies and targeted therapies, to improve patient survival rates and reduce adverse effects. Additionally, these players are expanding their product portfolios through mergers, acquisitions, and licensing agreements to broaden their market presence and offer comprehensive solutions. They emphasize personalized medicine approaches, aiming to tailor treatments based on individual patient characteristics. For instance, in April 2023, Eisai initiated the "Made of More" initiative to foster a community for individuals affected by head and neck cancer. Additionally, Eisai is presently conducting trials combining its approved cancer medication, Lenvima, with other oncology drugs for treating head and neck cancers.
The head and neck cancer therapeutics market experienced significant disruption due to the COVID-19 pandemic. The health crisis particularly affected highly immunocompromised cancer patients, leading to strict lockdowns that hindered their access to essential treatments. Additionally, cancer screenings, preventive healthcare services, and elective surgeries were often delayed, except in cases where the benefits outweighed the risks and to prioritize hospital resources for COVID-19 care.
An article published by NCBI (National Center for Biotechnology Information) highlighted that elective surgeries, including head and neck cancer surgeries, were postponed in many countries. Approximately 60% of scheduled outpatient visits at the European Institute of Oncology (IEO) were delayed. The diversion of medical resources to attend COVID-19 patients resulted in a setback for head and neck cancer treatment, leading to increased tumor growth, recurrence, and high mortality rates. As a result, the COVID-19 pandemic significantly impacted the head and neck cancer diagnostics market.
With ongoing research and development, innovative treatments targeting PD-1/PD-L1 pathways have redefined the market. Additionally, companies are emerging with novel therapies, fostering a competitive market. The outlook is promising, emphasizing precision medicine, combination therapies, and biomarker research. Key players are intensifying efforts in clinical trials and strategic collaborations, underscoring a robust drive towards personalized and more effective treatments, potentially transforming the head and neck cancer market.
In August 2022, Genexine Inc, a clinical-stage biotech firm specializing in immunotherapeutics, announced the initiation of patient dosage in a phase II clinical trial. Employing a triple combination therapy comprising GX-188E (a therapeutic DNA vaccine), GX-I7 (a prolonged-acting interleukin 7), and OpdivoR (nivolumab), a PD-1 immune checkpoint inhibitor, the company aimed to treat metastatic head and neck squamous cell carcinoma.
All segments will be provided for all regions and countries covered:
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.