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704952

消化器治療薬の世界市場 - 成長率、動向、予測:2021年~2026年

Gastrointestinal Therapeutics Market - Growth, Trends , COVID-19 Impact , and Forecasts (2021 - 2026)

出版日: | 発行: Mordor Intelligence Pvt Ltd | ページ情報: 英文 113 Pages | 納期: 2-3営業日

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消化器治療薬の世界市場 - 成長率、動向、予測:2021年~2026年
出版日: 2021年07月01日
発行: Mordor Intelligence Pvt Ltd
ページ情報: 英文 113 Pages
納期: 2-3営業日
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  • 概要
  • 目次
概要

消化器治療薬市場は、主に消化管疾患につながるライフスタイルの変化によって促進されています。2017年のNational Health Interview Surveyによると、米国において1530万人の成人が潰瘍と診断されました。

当レポートでは、世界における消化器治療薬市場の分析を薬剤タイプ・剤形・適応症および地域別に提供しており、競合情勢、主要企業のプロファイルなどとともにお届けします。

第1章 イントロダクション

第2章 調査手法

第3章 エグゼクティブサマリー

第4章 市場力学

  • 市場概要
  • 市場促進要因
  • 市場抑制要因
  • ファイブフォース分析

第5章 市場区分

  • 薬剤タイプ別
    • 制酸薬
    • 便秘薬
    • 止瀉薬
    • 制吐薬
    • 抗潰瘍薬
    • その他
  • 剤形別
    • 経口薬
    • 非経口薬
    • その他
  • 適応症別
    • 潰瘍性大腸炎
    • 過敏性腸症候群
    • クローン病
    • セリアック病
    • 胃腸炎
    • その他
  • 地域別
    • 北米
    • 欧州
    • アジア太平洋地域
    • 中東・アフリカ
    • 南米

第6章 競合情勢

  • 企業プロファイル
    • Abbott Laboratories
    • Allergan PLC
    • アステラス製薬
    • AstraZeneca
    • Bayer AG
    • GlaxoSmithKline PLC
    • Janssen Pharmaceuticals, Inc. (Johnson & Johnson)
    • Pfizer Inc.
    • AbbVie, Inc.
    • 武田薬品工業

第7章 市場機会と将来動向

目次
Product Code: 62814

The Gastrointestinal Therapeutics Market is expected to register a CAGR of 6.8% during the forecast period.

According to a research study by Hunt R.H.a et al., published in Digestive Diseases Journal March 2021, the study results found that digestive system may be affected by the SARS-CoV-2 virus, and those with pre-existing disease are at greatest risk of adverse outcomes. Some repurposed drugs used against COVID-19 can cause or aggravate some of the COVID-19-related gastrointestinal symptoms and can also induce liver injury.

In addition, according to a research study by Qing Ye et al., published in American Journal of Physiology August 2020, COVID-19 Cases with gastrointestinal symptoms are more likely to be complicated by liver injury and acute respiratory distress syndrome (ARDS). If not treated in time, coma and circulatory failure may occur.

The major factors that contribute to the growth of the gastrointestinal therapeutics market include the increasing prevalence of gastrointestinal diseases due to unhealthy dietary habits, additional numbers of clinical trials with accurate results, increasing healthcare expenditure, and growth in the geriatric population.

The increasing burden of gastrointestinal disorders in the country is also making market more lucrative. For instance, according to the research study by Thomas Joshua Pasvol et al., published in BMC Journal August 2020, in United Kingdom, the incidence of inflammatory bowel disease (IBD), Crohn's disease (CD) and ulcerative colitis (UC) was found to be 28.6, 10.2 and 15.7/100,000 population, respectively. Moreover, in adolescents aged 10-16 years, incidence of inflammatory bowel disease (IBD) was increased from 13.1 in 2000 to 25.4/100,000 population in 2018, respectively.

Therefore a wide range of new generation therapeutics is found targeting that include novel small molecules and cellular therapy are currently under investigation. Other driving factors include the rising surgical treatments and hospitalizations, due to GI diseases, and increasing R&D investments by biopharmaceutical companies in developing biologics and biosimilars. According to the National Clinical Trial (NCT) registry, as of May 2021, there are around 6,443 ongoing clinical trials related to gastrointestinal diseases across diferent phases of development. The positive outcomes from these studies can expect new effective therapeutics in near future.

There is a rising trend towards the development of effective therapeutics products by the market players. The companies are majorly expanding their pipeline and product portfolio through collaborations with specialized companies in the gastrointestinal therapeutics. For instance, in July 2018, HiFiBiO Therapeutics collaborated with Takeda, in a multi-target agreement for the discovery of breakthrough antibody therapies to potentially treat a variety of gastrointestinal diseases and other disorders.

However, risk factors, such as those related to the physiological, behavioral, psychosocial, and socio-environmental aspects, restrict the populations from reporting the diseases early, which reflects the low awareness and the economic burden. These risk factors and the increasing number of patent expirations restrict the growth of the gastrointestinal therapeutics market.

Key Market Trends

Ulcerative Colitis Segment is Found to Witness Healthy Growth Rate Over the Forecast Period

The growth of Ulcerative colitis segment can be attributed to the easy availability of drugs in the market to treat this condition. The segment is also anticipated to grow at a considerable rate owing to high clinical urgency to curb the growing prevalence of ulcerative colitis. This high prevalence is due to poor prognosis and consumption of unhealthy food, which may result in a high probability of disease recurrence.

The COVID-19 pandemic has increased concern regarding SARS-CoV-2 infection in inflammatory bowel disease (IBD) patients, especially those on immunosuppressive therapies or with active disease. For instance, according to a research study by Anupam Kumar Singh et al., published in United European Gastroenterology Journal March 2021, the study results found that risk of adverse outcomes of COVID-19 will be higher in patients with ulcerative colitis than in patients with Crohn's disease.

According to a research study by Shinji Okabayashi et al., published in Journal of the Anus, Rectum and Colon January 2020, in Japan, there were around 180,000 patients with ulcerative colitis. In addition, in Latin America, the incidence and prevalence of ulcerative colitis (UC) has been reported to be rising in newly industrialised regions. According to a research study by Paulo Gustavo Kotze et al., published in Therapeutic Advances in Gastroenterology Journal July 2020, the incidence and prevalence of ulcerative colitis (UC) in Latin America was between 0.04 to 8.00/100,000 and 0.23 to 76.1/100,000, respectively.

Increasing research and development activities is also boosting the market growth. According to the National Clinical Trial (NCT) registry, as of May 2021, there are around 245 ongoing clinical trials related to ulcerative colitis across diferent phases of development. The positive outcomes from these studies can expect new effective therapeutics for ulcerative colitis in coming years.

In addition, Takeda Pharmaceuticals, Jassen Pharmaceuticals, and Pfizer are among the major global companies that have established themselves with their products for the treatment of inflammatory ulcerative colitis. Moreover, the increasing involvement of key players in product development related to the field is anticipated to drive the segment growth. For instance, in March 2019, Johnson & Johnson announced the new clinical data from its Phase III UNIFI study showing positive results of STELARA in adults suffering from moderate to severe ulcerative colitis.

In addition, in August 2018, Pfizer Inc. received marketing approval for XELJANZ from the European Union in the treatment of moderate to severe ulcerative colitis. The novel launch of products from this strong pipeline is anticipated to propel market growth over the forecast period.

North America Dominates the Market and Expected to do Same in the Forecast Period

Some of the factors that are driving the market growth in North America region include technological advancements, growing number of gastrointestinal diseases, rising geriatric population and obese population, increasing research and development activities along with presence of key market players.

The COVID-19 infection is noted to be more severe in patients with co-morbid conditions, those who are immunosuppressed, malnourished and immunocompromised. Inflammatory bowel disease (IBD) which includes Crohn's disease and ulcerative colitis is chronic remitting and relapsing disorders with intestinal and extraintestinal manifestation. Inflammatory bowel disease (IBD) patients are often malnourished and on immunosuppressive medications and there is a hypothetical concern that IBD patients are at substantial risk of COVID-19 infection.

According to a research study by Maliha Naseer published in World Journal of Meta-AnalysisOctober 2020,in the United States, the management of inflammatory bowel disease (IBD) patients was often complex and poses unique challenges for gastroenterologists during the COVID-19 pandemic. The study results found that, during the COVID-19 pandemic 2020, IBD patients continued their medications and followed universal precautions i.e. masks, hand and respiratory hygiene and avoidance of health care facilities and public toilets as general population. Among IBD patients older age, having active disease, and co-morbid conditions are risk factors for a severe COVID-19 infection.

According to a research study by Gilaad G Kaplan et al., published in Journal of the Canadian Association of Gastroenterology February 2019, Canada has among the highest prevalence and incidence of inflammatory bowel disease (IBD) in the world. Moreover, the prevalence of inflammatory bowel disease (IBD) in 2018 was 0.7% of the Canadian population. This number is projected to rise to 1.0% of the population by 2030. In 2018, the number of Canadians with IBD was approximately 270,000 and is predicted to rise to 403,000 Canadians in 2030. This factor is expected to drive market growth as this will increase demand for GI therapeutics in the management of the disease.

The market players have adopted various strategies such as investment in research and development, product portfolio expansion, development of novel ulcerative colitis and Crohn's disease therapeutics, mergers and acquisitions to establish a strong distribution network. For instance, in February 2018, Janssen Biotech, Inc. and Theravance Biopharma, Inc. entered into a worldwide collaboration to develop TD-1473 for the treatment of inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease.

In addition, in April 2019, Salix Pharmaceuticals (Bausch Health Companies Inc.) entered into an exclusive license agreement with Mitsubishi Tanabe Pharma to commercialize and develop late stage investigational S1P modulators for the treatment of inflammatory bowel disease. Thus, owing to above mentioned factors it is expected to drive market growth in North America region during the forecast period.

Competitive Landscape

The Gastrointestinal Therapeutics Market is moderately competitive. These market players have extensively employed competition sustainability strategies such as new product development and regional and distribution channel expansion to gain a higher share in the market. Moreover, increased focus on refining operation and supply chain management has facilitated key players to maintain a competitive edge. Some of the market players include Abbott Laboratories, Takeda Pharmaceutical Company Limited, Abbvie Inc., Bayer AG and Cipla Inc. , among others.

Reasons to Purchase this report:

  • The market estimate (ME) sheet in Excel format
  • 3 months of analyst support

TABLE OF CONTENTS

1 INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Prevalence of GI Diseases
    • 4.2.2 Rising Investments in R&D by Pharmaceutical Companies
  • 4.3 Market Restraints
    • 4.3.1 Rising Socio-economic Burden Associated with Gastrointestinal Disorders
    • 4.3.2 Increasing Number of Patent Expiries
  • 4.4 Porter's Five Force Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5 MARKET SEGMENTATION

  • 5.1 By Drug Type
    • 5.1.1 Antacids
    • 5.1.2 Laxatives
    • 5.1.3 Antidiarrheal agents
    • 5.1.4 Antiemetics
    • 5.1.5 Antiulcer agents
    • 5.1.6 Other Drug Types
  • 5.2 By Dosage Form
    • 5.2.1 Oral
    • 5.2.2 Parenteral
    • 5.2.3 Other Dosage Forms
  • 5.3 By Application
    • 5.3.1 Ulcerative Colitis
    • 5.3.2 Irritable Bowel Syndrome
    • 5.3.3 Crohn's Disease
    • 5.3.4 Celiac Disease
    • 5.3.5 Gastroenteritis
    • 5.3.6 Other Applications
  • 5.4 Geography
    • 5.4.1 North America
      • 5.4.1.1 United States
      • 5.4.1.2 Canada
      • 5.4.1.3 Mexico
    • 5.4.2 Europe
      • 5.4.2.1 Germany
      • 5.4.2.2 United Kingdom
      • 5.4.2.3 France
      • 5.4.2.4 Italy
      • 5.4.2.5 Spain
      • 5.4.2.6 Rest of Europe
    • 5.4.3 Asia-Pacific
      • 5.4.3.1 China
      • 5.4.3.2 Japan
      • 5.4.3.3 India
      • 5.4.3.4 Australia
      • 5.4.3.5 South Korea
      • 5.4.3.6 Rest of Asia-Pacific
    • 5.4.4 Middle East and Africa
      • 5.4.4.1 GCC
      • 5.4.4.2 South Africa
      • 5.4.4.3 Rest of Middle East and Africa
    • 5.4.5 South America
      • 5.4.5.1 Brazil
      • 5.4.5.2 Argentina
      • 5.4.5.3 Rest of South America

6 COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Abbott Laboratories
    • 6.1.2 Abbvie Inc.
    • 6.1.3 AstraZeneca Plc
    • 6.1.4 Bayer AG
    • 6.1.5 GlaxoSmithKline PLC
    • 6.1.6 Janssen Pharmaceuticals Inc. (Johnson & Johnson)
    • 6.1.7 Pfizer Inc.
    • 6.1.8 AbbVie Inc.
    • 6.1.9 Takeda Pharmaceutical Company Limited
    • 6.1.10 Bausch Health Companies Inc. (Salix Pharmaceuticals, Inc.)
    • 6.1.11 Boehringer Ingelheim GmbH
    • 6.1.12 Cipla Inc

7 MARKET OPPORTUNITIES AND FUTURE TRENDS