多発性骨髄腫治療薬の市場規模、シェア、動向、予測：療法、薬剤タイプ、エンドユーザー、流通チャネル、地域別、2025～2033年

多発性骨髄腫治療薬の世界市場規模は2024年に234億6,000万米ドルとなりました。今後、IMARC Groupは、2033年には368億6,000万米ドルに達し、2025～2033年にかけて4.89%のCAGRを示すと予測しています。現在、北米が市場を独占しており、2024年には40.7%を超える大きな市場シェアを占めています。この優位性は、先進的ヘルスケアインフラ、革新的な治療法の高い採用率、腫瘍学研究への多額の投資によってもたらされています。主要製薬企業の存在と有利な償還施策が、同地域の多発性骨髄腫治療薬市場シェアをさらに押し上げています。

精密医療アプローチとバイオマーカー主導の治療戦略の急増が市場を後押ししています。二重特異性抗体や次世代プロテアソーム阻害剤を含む新規創薬への製薬企業による投資の増加は、治療の選択肢を広げています。世界各地域における臨床検査デザインの強化と適応的な規制経路により、革新的医薬品の市場投入までの時間が短縮されています。さらに、画像診断とゲノミクスの改善により疾患分類が精緻化され、より個別化された治療レジメンが可能となっています。患者の反応をモニタリングし、アドヒアランスを向上させるためのデジタルヘルス技術の導入が進んでいることも、重要な役割を果たしています。バイオテクノロジー企業と研究機関の戦略的提携は、現在進行中の治療法の進歩をさらに後押ししています。

米国では、腫瘍学研究のための連邦政府からの旺盛な資金援助と先進的ヘルスケアインフラの存在が市場の成長を牽引しています。CAR-T細胞療法や抗体薬剤複合体を含む画期的な治療法の採用率が高く、市場浸透が加速しています。強力な商業化能力を持つ大手製薬企業の存在が、迅速な薬剤展開を支えています。さらに、メディケアや民間保険会社を通じた有利な償還の枠組みが、高額な治療へのアクセスを向上させています。高齢化と平均寿命の伸びも、疾病の発生率上昇に寄与しています。例えば、2025年5月、ADVANCE検査において、ダラツムマブを含む4剤併用療法（DKRd）が、新たに多発性骨髄腫と診断された患者の予後を改善しました。標準的なKRdレジメンと比較して、DKRdは毒性を有意に増加させることなく、MRD陰性率がより高く（59%対36%）、無増悪生存期間が約33ヵ月（86%対79%）改善しました。これらの知見は、DKRdが新たな標準治療となる可能性を支持し、一部の患者は幹細胞移植を延期することが可能となり、治療方針の決定におけるMRD陰性の重要性が強調されました。

多発性骨髄腫治療薬市場動向

血液がんの負担増が薬剤需要を押し上げる

血液悪性腫瘍の世界の罹患率の増加は、多発性骨髄腫治療薬市場に大きな影響を与えています。2022年には、これらのがんは、診断されたがん患者全体の6.6％、関連死亡の7.2％を占め、標的治療に対する重大な必要性が浮き彫りになっています。多発性骨髄腫は主に遺伝子異常に起因するため、その治療には免疫調節薬、化学療法、放射線療法、幹細胞移植を含む集学的アプローチが必要となります。血小板輸血も副作用を管理する役割を果たします。早期発見が改善され、より多くの患者が先進的治療を受けられるようになりました。世界のヘルスケアシステムは効果的な治療法を提供する必要に迫られており、これが技術革新を加速し、骨髄腫に特化した薬剤への投資を後押ししているため、多発性骨髄腫治療薬市場の展望は明るいです。

治療革新を加速する技術の進歩

技術の進歩は、特にマイクロRNAベース治療やナノメディシンなどの革新を通じて、多発性骨髄腫治療薬に変革をもたらしつつあります。これらのプラットフォームは、健常組織へのダメージを最小限に抑えながら、悪性細胞を精密に標的化することを可能にします。その代表例が、オランダのオスにあるアルデナのナノメディシン施設で、2,000万ユーロの投資後、2024年11月にGMP認証を取得しました。この施設は、高分子薬剤を骨髄に運び、抗腫瘍反応を引き起こすのに重要な送達手段である脂質と高分子ナノ粒子の複雑な製造をサポートしています。このような技術革新は、治療成果を高めるだけでなく、合併症を減らすことで長期的なヘルスケアコストを削減します。製薬企業がナノテク能力を拡大するにつれて、これらの開発は多発性骨髄腫治療薬市場の成長を促進する上で重要な役割を果たすと予想されます。

生物学的療法の採用とヘルスケア支出の増加

生物製剤に関する認知度の高まりは、多発性骨髄腫の治療嗜好を変化させています。生物製剤は、免疫系を活用してがん細胞を認識・排除するもので、従来型治療法よりも侵襲性が低く、多くの場合、より効果的な代替療法を記載しています。患者は、全身的な副作用が少なく、標的を絞ったメカニズムを提供する治療法にますます惹かれています。この傾向とともに、2021年には世界のGDPの10.3%に相当する9兆8,000億米ドルと報告されている世界の医療支出の増加が、こうした先進治療への幅広いアクセスを可能にしています。製薬産業の研究予算拡大と相まって、生物製剤は先進国市場でも新興国市場でも人気を集めています。このシフトは、今後数年間の多発性骨髄腫治療薬市場の拡大に大きく寄与すると予想されます。

目次

第1章 序文

第2章 調査範囲と調査手法

• 調査の目的
• ステークホルダー
• データソース
  • 一次情報
  • 二次情報
• 市場推定
  • ボトムアップアプローチ
  • トップダウンアプローチ
• 調査手法

第3章 エグゼクティブサマリー

第4章 イントロダクション

第5章 パイプライン評価/臨床検査製品/臨床開発

• ペグイントロン（ペグ化インターフェロンアルファ-2b）
• ポマリドミド
• タネスピマイシン（KOS-953）
• MLN 9708
• SRT-501-012
• BHQ880
• パノビノスタット
• ZIO-101
• VEGFトラップ（アフリベルセプト）
• デノスマブ
• ペリフォシン
• アクチミド（CC-5013）
• ロミデプシン
• プリチデプシン（アプリジン）
• テムシロリムス（トリセル）
• ソラフェニブ
• ベバシズマブ

第6章 世界の多発性骨髄腫治療薬市場

• 市場概要
• 市場実績
• COVID-19の影響
• 市場予測

第7章 市場内訳：療法別

• 標的療法
• 生物学的療法
• 化学療法
• その他

第8章 市場内訳：薬剤タイプ別

• 免疫調節薬
• プロテアソーム阻害剤
• ヒストン脱アセチル化酵素阻害剤
• モノクローナル抗体医薬品
• ステロイド
• その他

第9章 市場内訳：エンドユーザー別

• 男性
• 女性

第10章 市場内訳：流通チャネル別

• 病院薬局
• 小売薬局
• オンライン薬局
• その他

第11章 市場内訳：地域別

• 北米
  • 米国
  • カナダ
• アジア太平洋
  • 中国
  • 日本
  • インド
  • 韓国
  • オーストラリア
  • インドネシア
  • その他
• 欧州
  • ドイツ
  • フランス
  • 英国
  • イタリア
  • スペイン
  • ロシア
  • その他
• ラテンアメリカ
  • ブラジル
  • メキシコ
  • その他
• 中東・アフリカ

第12章 SWOT分析

第13章 バリューチェーン分析

第14章 ポーターのファイブフォース分析

第15章 価格指標

第16章 競合情勢

• 市場構造
• 主要企業
• 主要企業のプロファイル
  • Amgen Inc.
  • Bristol Myers Squibb
  • Daiichi Sankyo Co.
  • Sanofi-Aventis Groupe（Genzyme Corporation）
  • Johnson & Johnson Services, Inc.
  • Merck & Co., Inc.
  • Novartis International AG
  • Pfizer Inc.
  • PHARMA MAR, S.A.
  • Takeda Pharmaceutical Company Limited.
  • Teva Pharmaceutical Industries Ltd.

List of Figures

• Figure 1: Global: Multiple Myeloma Drugs Market: Major Drivers and Challenges
• Figure 2: Global: Multiple Myeloma Drugs Market: Sales Value (in Billion USD), 2019-2024
• Figure 3: Global: Multiple Myeloma Drugs Market: Breakup by Therapy (in %), 2024
• Figure 4: Global: Multiple Myeloma Drugs Market: Breakup by Drug Type (in %), 2024
• Figure 5: Global: Multiple Myeloma Drugs Market: Breakup by End-User (in %), 2024
• Figure 6: Global: Multiple Myeloma Drugs Market: Breakup by Distribution Channel (in %), 2024
• Figure 7: Global: Multiple Myeloma Drugs Market: Breakup by Region (in %), 2024
• Figure 8: Global: Multiple Myeloma Drugs Market Forecast: Sales Value (in Billion USD), 2025-2033
• Figure 9: Global: Multiple Myeloma Drugs (Targeted Therapy) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 10: Global: Multiple Myeloma Drugs (Targeted Therapy) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 11: Global: Multiple Myeloma Drugs (Biologic Therapy) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 12: Global: Multiple Myeloma Drugs (Biologic Therapy) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 13: Global: Multiple Myeloma Drugs (Chemotherapy) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 14: Global: Multiple Myeloma Drugs (Chemotherapy) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 15: Global: Multiple Myeloma Drugs (Others) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 16: Global: Multiple Myeloma Drugs (Others) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 17: Global: Multiple Myeloma Drugs (Immunomodulatory Drugs) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 18: Global: Multiple Myeloma Drugs (Immunomodulatory Drugs) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 19: Global: Multiple Myeloma Drugs (Proteasome Inhibitors) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 20: Global: Multiple Myeloma Drugs (Proteasome Inhibitors) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 21: Global: Multiple Myeloma Drugs (Histone Deacetylase Inhibitors) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 22: Global: Multiple Myeloma Drugs (Histone Deacetylase Inhibitors) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 23: Global: Multiple Myeloma Drugs (Monoclonal Antibody Drugs) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 24: Global: Multiple Myeloma Drugs (Monoclonal Antibody Drugs) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 25: Global: Multiple Myeloma Drugs (Steroids) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 26: Global: Multiple Myeloma Drugs (Steroids) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 27: Global: Multiple Myeloma Drugs (Others) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 28: Global: Multiple Myeloma Drugs (Others) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 29: Global: Multiple Myeloma Drugs (Men) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 30: Global: Multiple Myeloma Drugs (Men) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 31: Global: Multiple Myeloma Drugs (Women) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 32: Global: Multiple Myeloma Drugs (Women) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 33: Global: Multiple Myeloma Drugs (Hospital Pharmacies) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 34: Global: Multiple Myeloma Drugs (Hospital Pharmacies) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 35: Global: Multiple Myeloma Drugs (Retail Pharmacies) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 36: Global: Multiple Myeloma Drugs (Retail Pharmacies) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 37: Global: Multiple Myeloma Drugs (Online Pharmacies) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 38: Global: Multiple Myeloma Drugs (Online Pharmacies) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 39: Global: Multiple Myeloma Drugs (Others) Market: Sales Value (in Million USD), 2019 & 2024
• Figure 40: Global: Multiple Myeloma Drugs (Others) Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 41: North America: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 42: North America: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 43: United States: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 44: United States: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 45: Canada: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 46: Canada: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 47: Asia Pacific: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 48: Asia Pacific: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 49: China: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 50: China: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 51: Japan: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 52: Japan: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 53: India: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 54: India: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 55: South Korea: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 56: South Korea: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 57: Australia: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 58: Australia: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 59: Indonesia: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 60: Indonesia: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 61: Others: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 62: Others: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 63: Europe: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 64: Europe: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 65: Germany: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 66: Germany: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 67: France: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 68: France: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 69: United Kingdom: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 70: United Kingdom: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 71: Italy: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 72: Italy: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 73: Spain: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 74: Spain: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 75: Russia: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 76: Russia: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 77: Others: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 78: Others: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 79: Latin America: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 80: Latin America: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 81: Brazil: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 82: Brazil: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 83: Mexico: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 84: Mexico: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 85: Others: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 86: Others: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 87: Middle East and Africa: Multiple Myeloma Drugs Market: Sales Value (in Million USD), 2019 & 2024
• Figure 88: Middle East and Africa: Multiple Myeloma Drugs Market: Breakup by Country (in %), 2024
• Figure 89: Middle East and Africa: Multiple Myeloma Drugs Market Forecast: Sales Value (in Million USD), 2025-2033
• Figure 90: Global: Multiple Myeloma Drugs Industry: SWOT Analysis
• Figure 91: Global: Multiple Myeloma Drugs Industry: Value Chain Analysis
• Figure 92: Global: Multiple Myeloma Drugs Industry: Porter's Five Forces Analysis

List of Tables

• Table 1: Global: Multiple Myeloma Drugs Market: Key Industry Highlights, 2024 and 2033
• Table 2: Global: Multiple Myeloma Drugs Market Forecast: Breakup by Therapy (in Million USD), 2025-2033
• Table 3: Global: Multiple Myeloma Drugs Market Forecast: Breakup by Drug Type (in Million USD), 2025-2033
• Table 4: Global: Multiple Myeloma Drugs Market Forecast: Breakup by End-User (in Million USD), 2025-2033
• Table 5: Global: Multiple Myeloma Drugs Market Forecast: Breakup by Distribution Channel (in Million USD), 2025-2033
• Table 6: Global: Multiple Myeloma Drugs Market Forecast: Breakup by Region (in Million USD), 2025-2033
• Table 7: Global: Multiple Myeloma Drugs Market Structure
• Table 8: Global: Multiple Myeloma Drugs Market: Key Players

The global multiple myeloma drugs market size was valued at USD 23.46 Billion in 2024. Looking forward, IMARC Group estimates the market to reach USD 36.86 Billion by 2033, exhibiting a CAGR of 4.89% during 2025-2033. North America currently dominates the market, holding a significant market share of over 40.7% in 2024. This dominance is driven by advanced healthcare infrastructure, high adoption of innovative therapies, and substantial investment in oncology research. The presence of key pharmaceutical companies and favorable reimbursement policies further fuel multiple myeloma drugs market share in the region.

The market is propelled by an upsurge in precision medicine approaches and biomarker-driven treatment strategies. Increasing investments by pharmaceutical companies in novel drug discovery, including bispecific antibodies and next-generation proteasome inhibitors, are expanding therapeutic options. Enhanced clinical trial designs and adaptive regulatory pathways in global regions are accelerating time-to-market for innovative drugs. Moreover, improvements in diagnostic imaging and genomics have refined disease classification, enabling more personalized treatment regimens. The growing incorporation of digital health technologies to monitor patient response and improve adherence also plays a significant role. Strategic collaborations among biotech firms and research institutions further support ongoing therapeutic advancements.

In the United States, the multiple myeloma drugs market growth is driven by robust federal funding for oncology research and the presence of an advanced healthcare infrastructure. The high adoption rate of breakthrough therapies, including CAR-T cell therapies and antibody-drug conjugates, is accelerating market penetration. The presence of major pharmaceutical players with strong commercialization capabilities supports rapid drug deployment. Additionally, favorable reimbursement frameworks through Medicare and private insurers improve access to costly treatments. An aging population and increasing life expectancy also contribute to rising disease incidence. For instance, in May 2025, a four-drug combination (DKRd) including daratumumab showed improved outcomes for newly diagnosed multiple myeloma patients in the ADVANCE trial. Compared to the standard KRd regimen, DKRd achieved higher MRD-negativity (59% vs. 36%) and better progression-free survival at nearly 33 months (86% vs. 79%), without significantly increased toxicity. These findings support DKRd as a potential new standard of care, enabling some patients to defer stem cell transplants and highlighting the importance of MRD-negativity in guiding treatment decisions.

Multiple Myeloma Drugs Market Trends:

Rising Burden of Hematological Cancers Boosting Drug Demand

The increasing incidence of hematologic malignancies globally is significantly influencing the multiple myeloma drug market. In 2022, these cancers accounted for 6.6% of all diagnosed cancer cases and 7.2% of related deaths, underscoring the critical need for targeted therapies. As multiple myeloma stems largely from genetic abnormalities, its treatment requires a multidisciplinary approach involving immunomodulatory drugs, chemotherapy, radiation, and stem cell transplants. Platelet transfusions also play a role in managing side effects. With early detection improving, more patients are eligible for advanced treatments. Healthcare systems worldwide are under pressure to offer effective therapeutics, which is accelerating innovation and boosting investments in myeloma-specific drugs, thus contributing to the positive multiple myeloma drugs market outlook.

Technological Advancements Accelerating Treatment Innovations

Technological progress is transforming multiple myeloma treatment, particularly through innovations like microRNA-based therapies and nanomedicines. These platforms enable precision targeting of malignant cells while minimizing damage to healthy tissues. A prime example is Ardena's nanomedicine facility in Oss, Netherlands, which secured GMP certification in November 2024 after a €20 million investment. This facility supports complex manufacturing of lipid and polymeric nanoparticles, delivery vehicles critical for transporting macromolecular agents to the bone marrow and triggering antitumor responses. Such innovations not only enhance treatment outcomes but also lower long-term healthcare costs by reducing complications. As pharmaceutical companies expand their nanotech capabilities, these developments are expected to play a vital role in driving the multiple myeloma drug market growth.

Increasing Biologic Therapy Adoption and Healthcare Spending

Growing awareness about biologic therapies is reshaping treatment preferences in the multiple myeloma landscape. These drugs leverage the immune system to recognize and eliminate cancer cells, offering a less invasive and often more effective alternative to conventional treatments. Patients are increasingly drawn to therapies that provide targeted mechanisms with fewer systemic side effects. Alongside this trend, rising global healthcare expenditures, reported at USD 9.8 Trillion in 2021, equating to 10.3% of global GDP, are enabling wider access to these advanced treatments. Combined with the pharmaceutical industry's expanding research budgets, biologic therapies are gaining traction across developed and emerging markets. This shift is expected to significantly contribute to the expansion of the multiple myeloma drug market in the coming years.

Multiple Myeloma Drugs Industry Segmentation:

Analysis by Therapy:

• Targeted Therapy
• Biologic Therapy
• Chemotherapy
• Others

Targeted therapy plays a pivotal role in the multiple myeloma drug market by offering a precision-based approach that directly interferes with specific molecules responsible for cancer cell growth and survival. These therapies, such as proteasome inhibitors and histone deacetylase inhibitors, provide enhanced efficacy with fewer side effects compared to traditional treatments. The increasing understanding of the genetic and molecular mechanisms of multiple myeloma has led to the development of more selective drugs. Ongoing clinical trials and regulatory approvals are further accelerating adoption. Moreover, the ability of targeted therapy to be used in combination regimens is expanding its clinical utility, driving consistent growth in this segment globally.

Biologic therapy has gained significant prominence in the multiple myeloma drug market, largely due to its ability to harness the body's immune system to combat cancer. Monoclonal antibodies, such as daratumumab and elotuzumab, have shown strong clinical success by targeting specific proteins on myeloma cells. The increasing acceptance of immunotherapy approaches and the growing demand for personalized medicine are key growth drivers for this segment. With rising awareness among healthcare providers and patients regarding the benefits of biologics, coupled with supportive reimbursement frameworks and expanding biologics pipelines, the segment is expected to experience sustained growth in both developed and emerging markets.

Chemotherapy continues to serve as a foundational component in the treatment of multiple myeloma, particularly in combination with other therapeutic classes. Although its prominence has somewhat declined with the emergence of targeted and biologic therapies, chemotherapy remains essential, especially in newly diagnosed or relapsed patients requiring rapid cytoreduction. The wide availability, proven efficacy, and cost-effectiveness of chemotherapeutic agents ensure their continued use. Advancements in formulation, including oral chemotherapies and supportive care options to manage side effects, have also contributed to maintaining its relevance. As part of combination regimens, chemotherapy enhances overall treatment outcomes, securing its ongoing role in the evolving multiple myeloma drug market.

Analysis by Drug Type:

• Immunomodulatory Drugs
• Proteasome Inhibitors
• Histone Deacetylase Inhibitors
• Monoclonal Antibody Drugs
• Steroids
• Others

Immunomodulatory drugs stand as the largest drug type in 2024, holding around 38.7% of the market. The immunomodulatory drugs segment dominates the multiple myeloma drug market due to its proven effectiveness in enhancing immune responses and directly targeting cancer cells. These drugs, such as lenalidomide and pomalidomide, have become foundational therapies for both newly diagnosed and relapsed patients, often used in combination with other treatments like corticosteroids and proteasome inhibitors. Their ability to modulate the tumor microenvironment, suppress abnormal plasma cells, and improve patient outcomes has led to widespread adoption. Additionally, ongoing clinical trials and regulatory approvals continue to expand their indications, reinforcing their central role in treatment protocols and sustaining their dominance in the multiple myeloma drug market.

Analysis by End User:

• Men
• Women

Men represent a significant segment in the multiple myeloma drug market, accounting for a higher prevalence rate compared to women. Epidemiological data indicate that men are more frequently diagnosed with multiple myeloma, which naturally drives greater demand for therapeutic interventions among this demographic. The higher incidence may be attributed to genetic, hormonal, and lifestyle factors, including greater exposure to environmental risk elements such as industrial chemicals and tobacco use. As a result, pharmaceutical companies and healthcare providers often prioritize this patient group in clinical trials and treatment planning. Increased health awareness, along with access to advanced diagnostics and treatment options, further supports the growth of this segment within the market.

Women constitute an essential and growing segment in the multiple myeloma drug market, supported by rising awareness and improving access to healthcare. Though the prevalence of multiple myeloma is relatively lower among women compared to men, the market demand from this group is expanding due to early diagnosis and increasing participation in screening programs. Advances in gender-specific research and the growing focus on tailoring therapies to address women's physiological responses contribute to better treatment outcomes. Additionally, supportive care services and educational initiatives have improved adherence to treatment regimens among female patients, fueling continued market growth in this segment.

Analysis by Distribution Channel:

• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies
• Others

Hospital pharmacies lead the market with around 57.0% of market share in 2024. The hospital pharmacies segment dominates the multiple myeloma drug market due to the complex nature of treatment regimens and the need for specialized administration and monitoring. Multiple myeloma therapies often involve intravenous drugs, combination treatments, and biologics that require hospital-grade infrastructure and professional supervision. Hospitals serve as primary points for cancer diagnosis, staging, and early treatment, making them central to drug dispensing and patient management. Furthermore, hospital pharmacies maintain a broader inventory of high-cost and high-risk oncology drugs, ensuring immediate access for patients undergoing intensive therapies. This central role in comprehensive cancer care reinforces their dominance in the multiple myeloma drug market.

Regional Analysis:

• North America
  • United States
  • Canada
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Indonesia
  • Others
• Europe
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Russia
  • Others
• Latin America
  • Brazil
  • Mexico
  • Others
• Middle East and Africa

In 2024, North America accounted for the largest market share of over 40.7%. North America dominates the multiple myeloma drug market due to its advanced healthcare infrastructure, high healthcare spending, and robust presence of leading pharmaceutical companies engaged in oncology research. The region benefits from early adoption of innovative therapies, strong regulatory support from agencies like the FDA, and widespread access to cutting-edge treatments. A high prevalence of multiple myeloma, combined with increased awareness and early diagnosis, contributes to the growing demand for targeted and biologic therapies. Additionally, favorable reimbursement policies and significant investment in clinical trials further strengthen North America's leadership in this space, ensuring its continued prominence in the multiple myeloma drug market. For instance, in June 2024, AbbVie begun its Phase III CERVINO trial for ABBV-383, a bispecific T-cell engager targeting BCMA and CD3, in patients with relapsed/refractory multiple myeloma. The global, randomized trial will enroll 380 patients who have had at least two prior therapies but not BCMA-targeted ones. Participants will receive ABBV-383 or standard available therapies. The primary endpoints are progression-free survival and overall response rate, with secondary measures including survival and disease symptom changes. ABBV-383 is dosed monthly to simplify treatment.

Key Regional Takeaways:

United States Multiple Myeloma Drugs Market Analysis

In 2024, the United States held a market share of over 86.8% in North America. The United States multiple myeloma drug market is primarily driven by the rising incidence of the disease, supported by improved diagnostic techniques that enable earlier detection and intervention. In 2025, the American Cancer Society projected approximately 36,110 new cases of multiple myeloma in the U.S. (20,030 in men, 16,080 in women) and about 12,030 related deaths (6,540 in men, 5,490 in women). In accordance with this, robust advancements in immunotherapy and precision medicine are fostering the development of novel drug classes and combination regimens, thereby impelling the market. The growing presence of a robust clinical trial pipeline, pushed by industry-academic collaborations, is further propelling market growth. Similarly, the growing awareness among healthcare providers and patients regarding early treatment options is enhancing adoption rates. Additionally, the market is benefiting from strategic mergers, acquisitions, and partnerships that strengthen research capabilities and expand portfolios. Apart from this, continued investments in biomarker-driven research and personalized medicine are driving targeted drug development and market expansion.

Europe Multiple Myeloma Drugs Market Analysis

The multiple myeloma drug market in Europe is experiencing growth due to the region's aging population, which elevates the prevalence of hematologic cancers requiring advanced treatments. It has been reported that Europe's median age is projected to rise by 5.5 years, from 44.7 in 2024 to 50.2 in 2100, with the share of people aged 80 and above expected to grow from 6.1% to 15.3%. In line with this, continued improvements in healthcare infrastructure across Europe are enhancing market accessibility. Similarly, the expansion of national cancer control programs, which promote earlier detection and the establishment of structured care pathways, is fostering market expansion. The increase in government funding dedicated to research on rare and complex diseases is driving pharmaceutical innovation. Additionally, the increasing acceptance of biosimilars is reducing treatment costs and expanding patient access to these therapies. Furthermore, the growing integration of digital health tools and electronic medical records, which improves personalized treatment planning and monitoring, is stimulating market appeal. Besides this, cross-border healthcare collaboration within the EU is strengthening knowledge exchange and accelerating the adoption of advanced multiple myeloma therapies across member states.

Asia Pacific Multiple Myeloma Drugss Market Analysis

The Asia Pacific market is largely driven by rising healthcare spending in emerging economies, which strengthens access to advanced oncology therapies. An industry report projected that India's healthcare spending will increase from 3.3% to 5% of GDP by 2030. Furthermore, rapid urbanization and changing lifestyles are increasing cancer prevalence, thereby strengthening market demand. The strong government initiatives to raise awareness of rare diseases and improve patient registries, which support early diagnosis and timely care, are bolstering market development. Additionally, strategic collaborations between regional biotech companies and global pharmaceutical firms are accelerating the transfer of technology and innovative drug development. The expansion of specialized cancer treatment centers and the growth of medical tourism infrastructure are attracting patients seeking advanced therapies. As such, India's medical tourism sector is expected to grow at a double-digit rate of 14-15% following the recent relaxation of visa rules outlined in the Union Budget 2025-26. Moreover, broader reimbursement coverage and regulatory reforms across key Asia-Pacific countries are facilitating the faster approval and availability of cutting-edge multiple myeloma treatments, thereby providing an impetus to the market.

Latin America Multiple Myeloma Drugss Market Analysis

In Latin America, the multiple myeloma drug market is growing due to the steady improvement of healthcare systems and greater public funding for oncology services across the region. Accordingly, by March 2025, Brazil's radiotherapy expansion plan, with Varian, added 92 linacs and nine HDR afterloaders, reducing wait times and enabling advanced treatments. The initiative now treats an estimated 55,000 cancer patients annually, expanding access nationwide. In addition to this, rising awareness initiatives and patient advocacy programs are encouraging earlier diagnosis and improved treatment uptake. The increasing presence of multinational pharmaceutical companies, through the formation of strategic partnerships and expansion of distribution channels, is bolstering market development. Furthermore, wider participation in international clinical trials is fostering scientific exchange and supporting faster access to advanced multiple myeloma therapies, thereby creating lucrative market opportunities.

Middle East and Africa Multiple Myeloma Drugs Market Analysis

The market in the Middle East and Africa is significantly influenced by rising healthcare expenditure and strong government initiatives to modernize oncology care. Industry analysis indicates that the UAE's healthcare spending ranks among the highest per capita globally, at approximately USD 1,200. The sector generates over USD 4.63 Billion in annual revenue and comprises 75 insurers, which provide more than 12,000 policies. Similarly, the continual development of regional cancer centers is expanding access to specialized diagnostics and advanced treatment options for multiple myeloma. Furthermore, increasing collaborations between local healthcare systems and global pharmaceutical companies are enhancing the market reach. Similarly, the growth of public-private partnerships and focused investments in training medical professionals is strengthening the oncology workforce, ensuring that patients receive high-quality, up-to-date care and improving overall treatment outcomes.

Competitive Landscape:

The competitive landscape of the multiple myeloma drug market is characterized by intense R&D activity, strategic collaborations, and continuous drug innovation. Leading players are focusing on expanding their product pipelines through the development of advanced biologics, immunotherapies, and targeted treatments. For instance, in June 2025, Glenmark's subsidiary, Ichnos Glenmark Innovation (IGI), reported promising early trial results for its cancer drug ISB 2001, targeting relapsed/refractory multiple myeloma. The novel trispecific antibody therapy showed a 79% overall response rate (ORR) among heavily pretreated patients, with 30% achieving complete or near-complete response. Six of eight patients tested negative for minimal residual disease. The trial, presented at ASCO 2025, showed manageable side effects and is moving into dose expansion to determine optimal dosing for broader testing. Regulatory approvals and fast-track designations are accelerating the launch of novel therapeutics, while mergers and licensing agreements are enhancing global reach and capabilities. Companies are increasingly investing in technologies such as CAR-T cell therapies and nanomedicine-based delivery systems to gain a competitive edge. With rising competition and robust clinical pipelines, the multiple myeloma drugs market forecast projects sustained innovation and market expansion through 2033, driven by unmet medical needs and a growing patient population worldwide.

The report provides a comprehensive analysis of the competitive landscape in the multiple myeloma drug market with detailed profiles of all major companies, including:

• Amgen Inc.
• Bristol Myers Squibb
• Daiichi Sankyo Co., Ltd.
• Sanofi-Aventis Groupe (Genzyme Corporation)
• Johnson & Johnson Services, Inc.
• Merck & Co., Inc.
• Novartis International AG
• Pfizer Inc.
• PHARMA MAR, S.A.
• Takeda Pharmaceutical Company Limited
• Teva Pharmaceutical Industries Ltd.

Key Questions Answered in This Report

• 1.How big is the multiple myeloma drug market?
• 2.What is the future outlook of multiple myeloma drug market?
• 3.What are the key factors driving the multiple myeloma drug market?
• 4.Which region accounts for the largest multiple myeloma drug market share?
• 5.Which are the leading companies in the global multiple myeloma drug market?

Table of Contents

1 Preface

2 Scope and Methodology

• 2.1 Objectives of the Study
• 2.2 Stakeholders
• 2.3 Data Sources
  • 2.3.1 Primary Sources
  • 2.3.2 Secondary Sources
• 2.4 Market Estimation
  • 2.4.1 Bottom-Up Approach
  • 2.4.2 Top-Down Approach
• 2.5 Forecasting Methodology

3 Executive Summary

4 Introduction

• 4.1 Overview
• 4.2 Key Industry Trends

5 Pipeline Assesment/Clinical Trial Products/Clinical Developments

• 5.1 PegIntron (Pegylated interferon alfa-2b)
• 5.2 Pomalidomide
• 5.3 Tanespimycin (KOS-953)
• 5.4 MLN 9708
• 5.5 SRT-501- 012
• 5.6 BHQ880
• 5.7 Panobinostat
• 5.8 ZIO-101
• 5.9 VEGF-Trap(Aflibercept)
• 5.10 Denosumab
• 5.11 Perifosine
• 5.12 Actimid (CC-5013)
• 5.13 Romidepsin
• 5.14 Plitidepsin (Aplidin)
• 5.15 Temsirolimus (Torisel)
• 5.16 Sorafenib
• 5.17 Bevacizumab

6 Global Multiple Myeloma Drugs Market

• 6.1 Market Overview
• 6.2 Market Performance
• 6.3 Impact of COVID-19
• 6.4 Market Forecast

7 Market Breakup by Therapy

• 7.1 Targeted Therapy
  • 7.1.1 Market Trends
  • 7.1.2 Market Forecast
• 7.2 Biologic Therapy
  • 7.2.1 Market Trends
  • 7.2.2 Market Forecast
• 7.3 Chemotherapy
  • 7.3.1 Market Trends
  • 7.3.2 Market Forecast
• 7.4 Others
  • 7.4.1 Market Trends
  • 7.4.2 Market Forecast

8 Market Breakup by Drug Type

• 8.1 Immunomodulatory Drugs
  • 8.1.1 Market Trends
  • 8.1.2 Market Forecast
• 8.2 Proteasome Inhibitors
  • 8.2.1 Market Trends
  • 8.2.2 Market Forecast
• 8.3 Histone Deacetylase Inhibitors
  • 8.3.1 Market Trends
  • 8.3.2 Market Forecast
• 8.4 Monoclonal Antibody Drugs
  • 8.4.1 Market Trends
  • 8.4.2 Market Forecast
• 8.5 Steroids
  • 8.5.1 Market Trends
  • 8.5.2 Market Forecast
• 8.6 Others
  • 8.6.1 Market Trends
  • 8.6.2 Market Forecast

9 Market Breakup by End-User

• 9.1 Men
  • 9.1.1 Market Trends
  • 9.1.2 Market Forecast
• 9.2 Women
  • 9.2.1 Market Trends
  • 9.2.2 Market Forecast

10 Market Breakup by Distribution Channel

• 10.1 Hospital Pharmacies
  • 10.1.1 Market Trends
  • 10.1.2 Market Forecast
• 10.2 Retail Pharmacies
  • 10.2.1 Market Trends
  • 10.2.2 Market Forecast
• 10.3 Online Pharmacies
  • 10.3.1 Market Trends
  • 10.3.2 Market Forecast
• 10.4 Others
  • 10.4.1 Market Trends
  • 10.4.2 Market Forecast

11 Market Breakup by Region

• 11.1 North America
  • 11.1.1 United States
    • 11.1.1.1 Market Trends
    • 11.1.1.2 Market Forecast
  • 11.1.2 Canada
    • 11.1.2.1 Market Trends
    • 11.1.2.2 Market Forecast
• 11.2 Asia Pacific
  • 11.2.1 China
    • 11.2.1.1 Market Trends
    • 11.2.1.2 Market Forecast
  • 11.2.2 Japan
    • 11.2.2.1 Market Trends
    • 11.2.2.2 Market Forecast
  • 11.2.3 India
    • 11.2.3.1 Market Trends
    • 11.2.3.2 Market Forecast
  • 11.2.4 South Korea
    • 11.2.4.1 Market Trends
    • 11.2.4.2 Market Forecast
  • 11.2.5 Australia
    • 11.2.5.1 Market Trends
    • 11.2.5.2 Market Forecast
  • 11.2.6 Indonesia
    • 11.2.6.1 Market Trends
    • 11.2.6.2 Market Forecast
  • 11.2.7 Others
    • 11.2.7.1 Market Trends
    • 11.2.7.2 Market Forecast
• 11.3 Europe
  • 11.3.1 Germany
    • 11.3.1.1 Market Trends
    • 11.3.1.2 Market Forecast
  • 11.3.2 France
    • 11.3.2.1 Market Trends
    • 11.3.2.2 Market Forecast
  • 11.3.3 United Kingdom
    • 11.3.3.1 Market Trends
    • 11.3.3.2 Market Forecast
  • 11.3.4 Italy
    • 11.3.4.1 Market Trends
    • 11.3.4.2 Market Forecast
  • 11.3.5 Spain
    • 11.3.5.1 Market Trends
    • 11.3.5.2 Market Forecast
  • 11.3.6 Russia
    • 11.3.6.1 Market Trends
    • 11.3.6.2 Market Forecast
  • 11.3.7 Others
    • 11.3.7.1 Market Trends
    • 11.3.7.2 Market Forecast
• 11.4 Latin America
  • 11.4.1 Brazil
    • 11.4.1.1 Market Trends
    • 11.4.1.2 Market Forecast
  • 11.4.2 Mexico
    • 11.4.2.1 Market Trends
    • 11.4.2.2 Market Forecast
  • 11.4.3 Others
    • 11.4.3.1 Market Trends
    • 11.4.3.2 Market Forecast
• 11.5 Middle East and Africa
  • 11.5.1 Market Trends
  • 11.5.2 Market Breakup by Country
  • 11.5.3 Market Forecast

12 SWOT Analysis

• 12.1 Overview
• 12.2 Strengths
• 12.3 Weaknesses
• 12.4 Opportunities
• 12.5 Threats

13 Value Chain Analysis

14 Porters Five Forces Analysis

• 14.1 Overview
• 14.2 Bargaining Power of Buyers
• 14.3 Bargaining Power of Suppliers
• 14.4 Degree of Competition
• 14.5 Threat of New Entrants
• 14.6 Threat of Substitutes

15 Price Indicators

16 Competitive Landscape

• 16.1 Market Structure
• 16.2 Key Players
• 16.3 Profiles of Key Players
  • 16.3.1 Amgen Inc.
    • 16.3.1.1 Company Overview
    • 16.3.1.2 Product Portfolio
    • 16.3.1.3 Financials
    • 16.3.1.4 SWOT Analysis
  • 16.3.2 Bristol Myers Squibb
    • 16.3.2.1 Company Overview
    • 16.3.2.2 Product Portfolio
    • 16.3.2.3 Financials
    • 16.3.2.4 SWOT Analysis
  • 16.3.3 Daiichi Sankyo Co.
    • 16.3.3.1 Company Overview
    • 16.3.3.2 Product Portfolio
    • 16.3.3.3 Financials
    • 16.3.3.4 SWOT Analysis
  • 16.3.4 Sanofi-Aventis Groupe (Genzyme Corporation)
    • 16.3.4.1 Company Overview
    • 16.3.4.2 Product Portfolio
    • 16.3.4.3 SWOT Analysis
  • 16.3.5 Johnson & Johnson Services, Inc.
    • 16.3.5.1 Company Overview
    • 16.3.5.2 Product Portfolio
    • 16.3.5.3 Financials
    • 16.3.5.4 SWOT Analysis
  • 16.3.6 Merck & Co., Inc.
    • 16.3.6.1 Company Overview
    • 16.3.6.2 Product Portfolio
    • 16.3.6.3 Financials
    • 16.3.6.4 SWOT Analysis
  • 16.3.7 Novartis International AG
    • 16.3.7.1 Company Overview
    • 16.3.7.2 Product Portfolio
    • 16.3.7.3 Financials
    • 16.3.7.4 SWOT Analysis
  • 16.3.8 Pfizer Inc.
    • 16.3.8.1 Company Overview
    • 16.3.8.2 Product Portfolio
    • 16.3.8.3 Financials
    • 16.3.8.4 SWOT Analysis
  • 16.3.9 PHARMA MAR, S.A.
    • 16.3.9.1 Company Overview
    • 16.3.9.2 Product Portfolio
    • 16.3.9.3 Financials
  • 16.3.10 Takeda Pharmaceutical Company Limited.
    • 16.3.10.1 Company Overview
    • 16.3.10.2 Product Portfolio
    • 16.3.10.3 Financials
    • 16.3.10.4 SWOT Analysis
  • 16.3.11 Teva Pharmaceutical Industries Ltd.
    • 16.3.11.1 Company Overview
    • 16.3.11.2 Product Portfolio
    • 16.3.11.3 Financials
    • 16.3.11.4 SWOT Analysis