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口腔乾燥症（ドライマウス病）治療の市場規模、シェア、動向、予測：タイプ別、薬剤タイプ別、流通チャネル別、地域別、2025～2033年

Xerostomia (Dry Mouth Disease) Therapeutics Market Size, Share, Trends and Forecast by Type, Drug Type, Distribution Channel, and Region, 2025-2033

出版日
発行
IMARC
ページ情報
英文 150 Pages
納期
2～3営業日
カスタマイズ可能
価格
価格表記: USDを日本円(税抜)に換算
本日の銀行送金レート: 1USD=146.06円
口腔乾燥症（ドライマウス病）治療の市場規模、シェア、動向、予測：タイプ別、薬剤タイプ別、流通チャネル別、地域別、2025～2033年
出版日: 2025年06月02日
発行: IMARC
ページ情報: 英文 150 Pages
納期: 2～3営業日
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概要

口腔乾燥症（ドライマウス病）治療の世界市場規模は、2024年に7億6,303万米ドルとなりました。今後、IMARC Groupは、市場は2033年までに10億731万米ドルに達し、2025～2033年にかけて2.98%のCAGRを示すと予測しています。北米は現在市場を独占しており、2024年には36.8％以上の市場シェアを占めています。これは、医療制度が確立されていること、疾患に対する理解が進んでいること、高齢者や薬剤療法によるドライマウスの発生率が増加していることなどが要因です。

口腔乾燥症（ドライマウス病）治療市場は、シェーグレン症候群、糖尿病、がん患者の放射線療法を含むドライマウス症状の発生率の上昇により拡大します。効果的な治療需要は、肺がんや高齢化とともに顕著な増加を目の当たりにしています。さらに、患者とともにヘルスケア専門家のドライマウス疾患に対する認識も高まっており、治療ソリューションの追求を後押ししています。さらに、分泌促進剤や代用唾液を含む薬剤製剤の改良は、これらの新しい製剤が患者により良い効果と快適さを提供することから、市場を前進させる要因となっています。個別化医療を重視したドラッグデリバリーシステムの技術的進歩も市場の成長に寄与しています。

米国では、口腔乾燥症治療市場は、加齢、糖尿病、がん治療（特に頭頸部放射線治療）などの危険因子の高い発生率とともに成長しています。標的治療の増加や市販製品の技術進歩により、患者にとって治療の選択肢が広がっています。例えば、産業の報告によると、ウィスコンシン大学医療部公衆衛生学部の研究者は、PACTと共同で、シェーグレン病の唾液腺機能を改善するために患者自身の強化された幹細胞を使用する可能性を探る臨床検査を行っています。この革新的なアプローチでは、患者の骨髄から幹細胞を抽出し、活性化させて唾液腺に注入します。さらに、口腔乾燥症が健康に与える影響についての理解が進むにつれて、米国では効果的で利用しやすい治療法に対する需要が着実に高まっていくと予想されます。

口腔乾燥症（ドライマウス病）治療市場動向

唾液分泌促進剤製剤の進歩

口腔乾燥症治療市場では、唾液分泌促進剤の製剤化が最も大きく進展しています。しかし、長期にわたる効果的な治療に対する需要が、こうした変化を促しています。古典的な唾液代用剤のほとんどは一時的な緩和しかもたらさないため、研究者は粘接着剤製剤、徐放性ゲル、ナノ粒子ベースの治療法など、より新しい、あるいは革新的なドラッグデリバリー方法を模索せざるを得なくなっています。企業はまた、この天然の唾液生産能力を代替するのではなく、刺激するための植物由来の化合物や再生医療アプローチに注目しています。成長因子や遺伝子治療のように、唾液腺機能を標的とした生物製剤が開発されており、長期的な利益をもたらす可能性があります。この開発により、保湿性の向上と再塗布の頻度の減少を通じて、患者のコンプライアンスと治療効果が改善されます。バイオアベイラビリティを向上させた処方箋ベースの製剤は、さらに市場の成長に拍車をかけています。65歳以上の高齢者の30％以上がドライマウスを経験しており、患者のコンプライアンスを改善し、持続的な緩和を提供する革新的なソリューションに対するニーズが高まっている、調査紙製は述べています。その結果、産業は対症療法的な緩和製品から、ドライマウスの原因を対象とした治療的介入へと移行しつつあります。これにより、患者の転帰がより良いものとなります。

OTC製品よりも処方薬の採用拡大

口腔乾燥症治療市場は、医療従事者の意識の高まりと、長期にわたる完全な管理に対する患者の関心に基づき、OTCドライマウス緩和製品から、より処方箋による医薬品へと移行しつつあります。人工唾液スプレー、トローチ、口内洗浄剤などのOTC製品は、単なる症状の緩和を提供するだけで、ドライマウスの根本的な原因を考慮していないです。一方、ピロカルピンやセビメリンなどの処方薬は、ムスカリン受容体作動薬として唾液腺機能を刺激し、長期にわたる効果をもたらします。さらに、臨床開発のための有望な薬剤候補は、唾液流量の増強と唾液腺の再生を伴うものであり、処方薬による治療がより現実的な選択肢として位置づけられています。ヘルスケア提供者は、シェーグレン症候群、放射線療法、またはポリファーマシー誘発性乾燥症に続発する慢性口腔乾燥症に苦しむ患者に配合治療を勧めるようになってきています。製薬企業が有効性と安全性のプロファイルを改善した標的治療の開発に投資を続けているため、このシフトは市場の成長を促進すると予想されます。化学療法を受けている患者の73.4%が口腔乾燥を経験しており、頭頸部がんの放射線療法を受けている患者の有病率は90%に上るという研究報告があります。この動向は、根本的な病態を対象とした処方箋ベースの治療法の採用を促進しています。

慢性疾患と薬剤による口腔乾燥症の有病率の上昇

口腔乾燥症患者の割合が増加している主要理由は、慢性疾患の増加と薬剤による副作用です。糖尿病、シェーグレン症候群、その他の自己免疫疾患などの病気は、唾液腺に直接影響を及ぼし、口腔乾燥症の症状が長期間続く原因となります。同様に、放射線療法や化学療法によるがん治療も唾液腺にダメージを与えることが多く、その結果、がん患者の一般的な副作用として口腔乾燥症が生じます。研究によると、口腔乾燥症は一般人口の13～17％が罹患しており、ポリファーマシーにより高齢者の有病率は30～40％に上昇します。さらに、抗高血圧薬、抗うつ薬、オピオイドなどの薬剤が広く使用されていることも、症例数増加の一因となっており、一般的に配合される400種類以上の薬剤が副作用として口渇を引き起こすことが知られています。口腔乾燥症に対する効果的な治療に対する需要は、地球全体の高齢化と慢性疾患の絶え間ない増加の中で高まると考えられます。そのため、製薬会社は症状の緩和をもたらし、ドライマウスの根本的な原因に対処できる薬剤の開発に乗り出しています。したがって、患者数の増加は口腔乾燥症治療市場の革新と成長のための重要な領域を示しています。

目次

第1章 序文

第2章 調査範囲と調査手法

  • 調査の目的
  • ステークホルダー
  • データソース
    • 一次情報
    • 二次情報
  • 市場推定
    • ボトムアップアプローチ
    • トップダウンアプローチ
  • 調査手法

第3章 エグゼクティブサマリー

第4章 イントロダクション

  • 概要
  • 主要産業動向

第5章 世界の口腔乾燥症（ドライマウス病）治療市場

  • 市場概要
  • 市場実績
  • COVID-19の影響
  • 市場予測

第6章 市場内訳：タイプ別

  • 人工唾液/唾液代替物
  • 唾液分泌促進剤

第7章 市場内訳：薬剤タイプ別

  • 市販薬
  • 処方薬

第8章 市場内訳：流通チャネル別

  • 病院薬局
  • 小売薬局
  • オンライン薬局

第9章 市場内訳：地域別

  • 北米
    • 米国
    • カナダ
  • アジア太平洋
    • 中国
    • 日本
    • インド
    • 韓国
    • オーストラリア
    • インドネシア
    • その他
  • 欧州
    • ドイツ
    • フランス
    • 英国
    • イタリア
    • スペイン
    • ロシア
    • その他
  • ラテンアメリカ
    • ブラジル
    • メキシコ
    • その他
  • 中東・アフリカ
    • 市場内訳：国別

第10章 SWOT分析

  • 概要
  • 強み
  • 弱み
  • 機会
  • 脅威

第11章 バリューチェーン分析

第12章 ポーターのファイブフォース分析

  • 概要
  • 買い手の交渉力
  • 供給企業の交渉力
  • 競合の程度
  • 新規参入業者の脅威
  • 代替品の脅威

第13章 価格分析

第14章 競合情勢

  • 市場構造
  • 主要企業
  • 主要企業のプロファイル
    • 3M Company
    • BIoTene（GSK plc）
    • Parnell Pharmaceuticals Inc.
    • Quest Products LLC
    • Saliwell Ltd
    • Sun Pharmaceutical Industries Limited
    • West-Ward Pharmaceutical（Hikma Pharmaceuticals plc）
図表

List of Figures

  • Figure 1: Global: Xerostomia Therapeutics Market: Major Drivers and Challenges
  • Figure 2: Global: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019-2024
  • Figure 3: Global: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 4: Global: Xerostomia Therapeutics Market: Breakup by Type (in %), 2024
  • Figure 5: Global: Xerostomia Therapeutics Market: Breakup by Drug Type (in %), 2024
  • Figure 6: Global: Xerostomia Therapeutics Market: Breakup by Distribution Channel (in %), 2024
  • Figure 7: Global: Xerostomia Therapeutics Market: Breakup by Region (in %), 2024
  • Figure 8: Global: Xerostomia Therapeutics (Artificial Saliva/Saliva Substitutes) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 9: Global: Xerostomia Therapeutics (Artificial Saliva/Saliva Substitutes) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 10: Global: Xerostomia Therapeutics (Salivary Stimulants) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 11: Global: Xerostomia Therapeutics (Salivary Stimulants) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 12: Global: Xerostomia Therapeutics (OTC) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 13: Global: Xerostomia Therapeutics (OTC) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 14: Global: Xerostomia Therapeutics (Prescription) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 15: Global: Xerostomia Therapeutics (Prescription) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 16: Global: Xerostomia Therapeutics (Hospital Pharmacy) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 17: Global: Xerostomia Therapeutics (Hospital Pharmacy) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 18: Global: Xerostomia Therapeutics (Retail Pharmacy) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 19: Global: Xerostomia Therapeutics (Retail Pharmacy) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 20: Global: Xerostomia Therapeutics (Online Pharmacy) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 21: Global: Xerostomia Therapeutics (Online Pharmacy) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 22: North America: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 23: North America: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 24: United States: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 25: United States: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 26: Canada: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 27: Canada: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 28: Asia-Pacific: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 29: Asia-Pacific: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 30: China: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 31: China: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 32: Japan: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 33: Japan: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 34: India: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 35: India: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 36: South Korea: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 37: South Korea: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 38: Australia: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 39: Australia: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 40: Indonesia: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 41: Indonesia: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 42: Others: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 43: Others: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 44: Europe: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 45: Europe: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 46: Germany: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 47: Germany: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 48: France: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 49: France: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 50: United Kingdom: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 51: United Kingdom: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 52: Italy: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 53: Italy: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 54: Spain: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 55: Spain: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 56: Russia: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 57: Russia: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 58: Others: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 59: Others: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 60: Latin America: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 61: Latin America: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 62: Brazil: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 63: Brazil: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 64: Mexico: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 65: Mexico: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 66: Others: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 67: Others: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 68: Middle East and Africa: Xerostomia Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 69: Middle East and Africa: Xerostomia Therapeutics Market: Breakup by Country (in %), 2024
  • Figure 70: Middle East and Africa: Xerostomia Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 71: Global: Xerostomia Therapeutics Industry: SWOT Analysis
  • Figure 72: Global: Xerostomia Therapeutics Industry: Value Chain Analysis
  • Figure 73: Global: Xerostomia Therapeutics Industry: Porter's Five Forces Analysis

List of Tables

  • Table 1: Global: Xerostomia Therapeutics Market: Key Industry Highlights 2024 and 2033
  • Table 2: Global: Xerostomia Therapeutics Market Forecast: Breakup by Type (in Million USD), 2025-2033
  • Table 3: Global: Xerostomia Therapeutics Market Forecast: Breakup by Drug Type (in Million USD), 2025-2033
  • Table 4: Global: Xerostomia Therapeutics Market Forecast: Breakup by Distribution Channel (in Million USD), 2025-2033
  • Table 5: Global: Xerostomia Therapeutics Market Forecast: Breakup by Region (in Million USD), 2025-2033
  • Table 6: Global: Xerostomia Therapeutics Market: Competitive Structure
  • Table 7: Global: Xerostomia Therapeutics Market: Key Players
目次
Product Code: SR112025A6439

The global xerostomia (dry mouth disease) therapeutics market size was valued at USD 763.03 Million in 2024. Looking forward, IMARC Group estimates the market to reach USD 1,007.31 Million by 2033, exhibiting a CAGR of 2.98% from 2025-2033. North America currently dominates the market, holding a market share of over 36.8% in 2024, attributed to a well-established healthcare system, increased disease understanding, and growing incidence of dry mouth due to the elderly population and medications.

The xerostomia (dry mouth disease) therapeutics market expands due to rising incidence of dry mouth conditions, involving Sjogren's syndrome, diabetes, and radiation therapy for cancer patients. The effective treatment demand is witnessing a notable increase with lung cancer and an aging population. Additionally, healthcare professionals alongside patients are increasingly aware of dry mouth disease which drives their pursuit of therapeutic solutions. Moreover, improved drug formulations, including secretagogues and saliva substitutes, profilerating the market forward as these new formulations provide better effectiveness and comfort to patients. Technological advances in drug delivery systems with emphasis on personalized medicine also contribute to the market's growth.

In the United States, the xerostomia therapeutics market is growing with a high incidence of risk factors like aging, diabetes, and cancer therapy, especially head and neck radiation. The increasing use of targeted therapies and technological advancements in over-the-counter products are offering increased treatment choices for patients. For instance, as per industry reports, researchers from University of Wisconsin School of Medicine Public Health, in partnership with PACT, is performing a clinical trial to explore the potential of using a patient's own enhanced stem cells to improve salivary gland function in Sjogren's disease. This innovative approach involves extracting stem cells from the patient's bone marrow, activating them, and injecting them into the salivary glands. Furthermore, as the understanding of xerostomia's impact on health continues to evolve, demand for effective and accessible treatments in the U.S. is expected to rise steadily.

Xerostomia (Dry Mouth Disease) Therapeutics Market Trends:

Advancements in Salivary Stimulant Formulations

The xerostomia therapeutics market has some of the most significant advancements in the formulation of salivary stimulants. The demand for prolonged and effective treatment is, however, driving these changes. Most of the classical saliva substitutes provide only temporary relief, forcing researchers to seek newer or innovative drug delivery methods like mucoadhesive formulations, sustained-release gels, and nanoparticle-based therapies. Companies have also turned their attention to plant-derived compounds or regenerative medicine approaches to stimulate rather than replace this natural saliva production capability. Biologics are being developed targeting salivary gland function, like growth factors and gene therapy, that might offer some long-term benefits. This development improves patient compliance and the efficacy of the treatment through improved moisture retention and decreased frequency of reapplication. Prescription-based formulations with enhanced bioavailability further add to the market's growth. With over 30% of individuals aged 65 and older experiencing dry mouth, there is a growing need for innovative solutions that improve patient compliance and offer sustained relief, a research article stated. As a consequence, the industry is moving away from symptomatic relief products towards therapeutic interventions targeting the cause of dry mouth. This will ensure better patient outcomes.

Growing Adoption of Prescription Therapies Over OTC Products

The market of xerostomia therapeutics is moving away from OTC dry mouth relief products to more prescription-based drugs based on the increasing awareness within the healthcare professional community and the patients' concern for complete long-term management. While OTC products such as artificial saliva sprays, lozenges, or mouth rinses provide mere symptom relief, it does not take into account the root causes of the dryness. On the other hand, prescription medications such as pilocarpine and cevimeline, muscarinic receptor agonists stimulate salivary gland function to produce long-lasting effects. In addition, promising drug candidates for clinical development involve enhancement of saliva flow and glandular regeneration that positions prescription treatments as a more viable option. The healthcare provider has increasingly become recommending prescription treatments to patients who suffer from chronic xerostomia secondary to Sjogren's syndrome, radiation therapy, or polypharmacy-induced dryness. This shift is expected to fuel market growth as pharmaceutical companies continue investing in the development of targeted treatments with improved efficacy and safety profiles. Studies suggest that up to 73.4% of patients undergoing chemotherapy report experiencing xerostomia, with the prevalence rising to 90% among those receiving radiation therapy for head and neck cancers. This trend is driving the adoption of prescription-based treatments targeting the underlying pathology.

Rising Prevalence of Xerostomia Due to Chronic Diseases and Medications

The principal reason for the rising rate of xerostomia cases is the increased number of chronic diseases and side effects from medication. Diseases like diabetes, Sjogren's syndrome, and other autoimmune diseases have a direct impact on salivary glands, causing symptoms of xerostomia to be felt for long durations. Similarly, cancer treatments through radiation therapy and chemotherapy often damage salivary glands, thereby resulting in xerostomia as a common side effect in cancer patients. Studies indicate that xerostomia affects 13-17% of the general population, with prevalence rates rising to 30-40% among the elderly due to polypharmacy. The widespread use of medications such as antihypertensives, antidepressants, and opioids further contributes to the rising number of cases, with over 400 commonly prescribed drugs known to cause dry mouth as a side effect. Demand for effective remedies against xerostomia will increase among the aging globe and the constantly growing burden of chronic diseases. As such, pharmaceutical companies are coming forward with the drugs that can offer symptomatic relief and address the underlying cause of dry mouth. The rising number of patients, thus, represents an important area for innovation and growth in the xerostomia therapeutics market.

Xerostomia (Dry Mouth Disease) Therapeutics Industry Segmentation:

Analysis by Type:

  • Artificial Saliva/Saliva Substitutes
  • Salivary Stimulants

Artificial saliva/saliva substitutes lead the market with around 65.7% of market share in 2024. due These products provide moisture, lubrication, and relief from dry mouth symptoms, improving patients' comfort and quality of life. Available in various forms, such as sprays, gels, and lozenges, artificial saliva products help alleviate discomfort caused by conditions like Sjogren's syndrome or medication-induced xerostomia. Their widespread use in both clinical settings and over-the-counter offerings, along with ongoing advancements in formulation, continues to drive demand, positioning them as a key treatment option for dry mouth management.

Analysis by Drug Type:

  • OTC
  • Prescription

OTC leads the market in 2024, driven by consumer preference for easily accessible, non-prescription solutions. OTC treatments, including mouthwashes, lozenges, gels, and sprays, offer immediate relief from dry mouth symptoms and are widely available in pharmacies and online. The growing trend of self-management and the increasing awareness of xerostomia contribute to the popularity of OTC products. Additionally, their affordability and convenience make them a preferred choice for patients seeking to manage mild to moderate cases of dry mouth without the need for a healthcare provider's prescription.

Analysis by Distribution Channel:

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy

Retail pharmacy leads the market with around 38.5% of market share in 2024, due to their wide accessibility and convenience for consumers. Patients can easily obtain over-the-counter (OTC) products such as mouthwashes, lozenges, and gels, which are commonly used to manage dry mouth symptoms. The growing preference for self-management of xerostomia, along with the increasing number of retail pharmacy chains globally, has bolstered this segment. Retail pharmacies also benefit from strong relationships with pharmaceutical companies, enabling them to stock a diverse range of therapeutics. Additionally, their ability to provide personalized advice and quick access further drives their dominance in the market.

Regional Analysis:

  • North America
    • United States
    • Canada
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Australia
    • Indonesia
    • Others
  • Europe
    • Germany
    • France
    • United Kingdom
    • Italy
    • Spain
    • Russia
    • Others
  • Latin America
    • Brazil
    • Mexico
    • Others
  • Middle East and Africa

In 2024, North America accounted for the largest market share of over 36.8%, driven by a high prevalence of dry mouth conditions, advanced healthcare infrastructure, and significant investments in research and development. The region's large aging population, particularly in the U.S., contributes to the rising incidence of xerostomia, often linked with medication use, autoimmune diseases, and radiation therapy for cancer treatment. For instance, industry reports state that the U.S. population aged 65 plus is projected to grow from 58 million in 2022 to 82 million by 2050, increasing from 17% to 23% of the total population. Additionally, the presence of key pharmaceutical companies, a robust pipeline of therapeutic products, and favorable reimbursement policies further support market growth. North America's demand for innovative treatments and patient-centered care strategies ensures its leadership in this market.

Key Regional Takeaways:

United States Xerostomia (Dry Mouth Disease) Therapeutics Market Analysis

In 2024, United States accounted for 88.6% of the market share in North America. The U.S. Xerostomia (Dry Mouth Disease) therapeutics market is growing due to the increasing number of chronic patients, such as diabetes and Sjogren's syndrome, among others. According to CDC, in 2023, about 37.3 million Americans had diagnosed diabetes, accounting for a big portion of individuals with dry mouth. Moreover, the growing need for prescription dry mouth treatments by cancer patients after radiation therapy enhances the demand. New saliva substitutes, oral sprays, and regenerative therapies are creating advanced treatment avenues. Developed healthcare system in the United States ensures increased accessibility to xerostomia treatments for patients. Major pharmaceutical giants, GlaxoSmithKline and Colgate-Palmolive, are looking for expansion in their portfolios of oral health care. Government-aided health care, Medicare, and Medicaid continue to make treatments affordable for patients, and increasing awareness programs also facilitate timely diagnosis and adherence to treatments. The integration of AI in dental healthcare is also improving patient outcomes, positioning the U.S. as a key market for xerostomia therapeutics.

Europe Xerostomia (Dry Mouth Disease) Therapeutics Market Analysis

The European Xerostomia therapeutics market is experiencing growth due to the aging population and increasing diabetes and autoimmune cases. It is estimated by the World Health Organization (WHO) that about 74 million adults and 300,000 children and adolescents in Europe are suffering from diabetes, the greatest risk factor for xerostomia. In addition, an increase in the number of cancer patients treated using radiation therapy causes a boosted demand for saliva substitutes and prescription treatments. Germany and France lead the market in terms of adoption since their healthcare systems are well established. Unilever and Reckitt companies are taking a challenge to apply innovative oral hydration solutions and prescription medicines. European Union rules promoting access to advanced patient therapies support market expansion, as increased research and development result in novel treatment solutions, positioning Europe as a central market for xerostomia therapeutics.

Asia Pacific Xerostomia (Dry Mouth Disease) Therapeutics Market Analysis

Asia Pacific is experiencing a huge growth in the Xerostomia therapeutics market due to the increasing diabetic population and the increasing awareness of oral health. The International Diabetes Federation (IDF) states that by 2023, China had around 140 million people living with diabetes, significantly contributing to the prevalence of dry mouth. The elderly population in Japan, at about 29% of the total population, further fuels the demand for xerostomia treatments. The potential for the market increases in addition to government healthcare services in the form of various schemes, such as Ayushman Bharat by India, which encourages oral health awareness. Herbal and natural saliva substitutes are emerging nowadays, especially in countries like China and India. Pharmaceutical companies like Sun Pharma and Takeda are increasing their market presence both domestically and internationally. The increasing use of digital healthcare platforms is enhancing access to treatment, making Asia Pacific a key region for market growth.

Latin America Xerostomia (Dry Mouth Disease) Therapeutics Market Analysis

The Latin American Xerostomia therapeutics market is growing because of increased investments in healthcare and the rising prevalence of chronic diseases. According to an industry report, Brazil's healthcare spending has reached USD 161 billion in 2023, with a significant share spent on oral health care, as per reports. Increasing cases of xerostomia caused by diabetes and cancer treatments are pushing the demand for therapeutic solutions. Brazil and Mexico have the largest market share in that region, therefore, are shifting their focus toward increasing prescription-only dry mouth therapies. According to an industry report, more than 1.7 million aesthetic and dental operations were conducted within Mexico in the year 2023, contributing to the augmented demand for oral hydration solutions. Multinational companies are coming together with regional firms to create advanced saliva substitutes and prescription-only medications. The market growth in the region is likely to be sustained by government-backed healthcare programs and rising private investments in oral health care.

Middle East and Africa Xerostomia (Dry Mouth Disease) Therapeutics Market Analysis

Middle East and Africa Xerostomia therapeutics market is also witnessing growth in this region as there is growing healthcare investment coupled with a higher incidence of chronic diseases such as diabetes. As per the UAE government data, the federal healthcare budget for 2022 was USD 1.16 billion. It allocated most of the healthcare budget to oral healthcare services. Diabetes is quite prevalent in this region, particularly in the gulf countries. The demand for prescription medication, such as pilocarpine, in Saudi Arabia is on the rise due to an incidence rate of over 18% for diabetes. In South Africa, increasing production by pharmaceutical companies contributes to increased oral hydration solution availability. Dental and oral healthcare awareness is further bolstering the market within the region. Investments in health infrastructure, along with collaborations between local and international pharmaceutical companies, are likely to boost the growth of advanced treatments for xerostomia.

Competitive Landscape:

The competition among the established pharmaceutical firms and emerging biotechnology companies drives the market for xerostomia (dry mouth disease) therapeutics. The key players are focused on the development and commercialization of some products, including saliva substitutes, secretagogues, and therapies focusing on the underlying causes of xerostomia. Companies are putting in substantial investments to create new drug formulations and sophisticated delivery systems to fill unmet needs in patient care. Besides, firms often take on strategic partnerships and acquisitions to base their portfolios of products and enhance market reach. Competition is further influenced by important aspects, such as regulatory approvals, pricing strategies, and clinical effectiveness. For instance, in December 2024, MeiraGTx Holdings announced that they received Regenerative Medicine Advanced Therapy (RMAT) designation from the FDA for their product AAV2-hAQP1 for the treatment of Grade 2/3 radiation-induced xerostomia. This designation highlights the therapy's potential to address unmet needs, expedite development, and enhance patient outcomes for those affected by radiation-induced dry mouth.

The report provides a comprehensive analysis of the competitive landscape in the xerostomia (dry mouth disease) therapeutics market with detailed profiles of all major companies, including:

  • 3M Company
  • Biotene (GSK plc)
  • Parnell Pharmaceuticals Inc.
  • Quest Products LLC
  • Saliwell Ltd
  • Sun Pharmaceutical Industries Limited
  • West-Ward Pharmaceutical (Hikma Pharmaceuticals plc)

Key Questions Answered in This Report

  • 1.How big is the xerostomia (dry mouth disease) therapeutics market?
  • 2.What is the future outlook of xerostomia (dry mouth disease) therapeutics market?
  • 3.What are the key factors driving the xerostomia (dry mouth disease) therapeutics market?
  • 4.Which region accounts for the largest xerostomia (dry mouth disease) therapeutics market share?
  • 5.Which are the leading companies in the global xerostomia (dry mouth disease) therapeutics market?q

Table of Contents

1 Preface

2 Scope and Methodology

  • 2.1 Objectives of the Study
  • 2.2 Stakeholders
  • 2.3 Data Sources
    • 2.3.1 Primary Sources
    • 2.3.2 Secondary Sources
  • 2.4 Market Estimation
    • 2.4.1 Bottom-Up Approach
    • 2.4.2 Top-Down Approach
  • 2.5 Forecasting Methodology

3 Executive Summary

4 Introduction

  • 4.1 Overview
  • 4.2 Key Industry Trends

5 Global Xerostomia (Dry Mouth Disease) Therapeutics Market

  • 5.1 Market Overview
  • 5.2 Market Performance
  • 5.3 Impact of COVID-19
  • 5.4 Market Forecast

6 Market Breakup by Type

  • 6.1 Artificial Saliva/Saliva Substitutes
    • 6.1.1 Market Trends
    • 6.1.2 Market Forecast
  • 6.2 Salivary Stimulants
    • 6.2.1 Market Trends
    • 6.2.2 Market Forecast

7 Market Breakup by Drug Type

  • 7.1 OTC
    • 7.1.1 Market Trends
    • 7.1.2 Market Forecast
  • 7.2 Prescription
    • 7.2.1 Market Trends
    • 7.2.2 Market Forecast

8 Market Breakup by Distribution Channel

  • 8.1 Hospital Pharmacy
    • 8.1.1 Market Trends
    • 8.1.2 Market Forecast
  • 8.2 Retail Pharmacy
    • 8.2.1 Market Trends
    • 8.2.2 Market Forecast
  • 8.3 Online Pharmacy
    • 8.3.1 Market Trends
    • 8.3.2 Market Forecast

9 Market Breakup by Region

  • 9.1 North America
    • 9.1.1 United States
      • 9.1.1.1 Market Trends
      • 9.1.1.2 Market Forecast
    • 9.1.2 Canada
      • 9.1.2.1 Market Trends
      • 9.1.2.2 Market Forecast
  • 9.2 Asia-Pacific
    • 9.2.1 China
      • 9.2.1.1 Market Trends
      • 9.2.1.2 Market Forecast
    • 9.2.2 Japan
      • 9.2.2.1 Market Trends
      • 9.2.2.2 Market Forecast
    • 9.2.3 India
      • 9.2.3.1 Market Trends
      • 9.2.3.2 Market Forecast
    • 9.2.4 South Korea
      • 9.2.4.1 Market Trends
      • 9.2.4.2 Market Forecast
    • 9.2.5 Australia
      • 9.2.5.1 Market Trends
      • 9.2.5.2 Market Forecast
    • 9.2.6 Indonesia
      • 9.2.6.1 Market Trends
      • 9.2.6.2 Market Forecast
    • 9.2.7 Others
      • 9.2.7.1 Market Trends
      • 9.2.7.2 Market Forecast
  • 9.3 Europe
    • 9.3.1 Germany
      • 9.3.1.1 Market Trends
      • 9.3.1.2 Market Forecast
    • 9.3.2 France
      • 9.3.2.1 Market Trends
      • 9.3.2.2 Market Forecast
    • 9.3.3 United Kingdom
      • 9.3.3.1 Market Trends
      • 9.3.3.2 Market Forecast
    • 9.3.4 Italy
      • 9.3.4.1 Market Trends
      • 9.3.4.2 Market Forecast
    • 9.3.5 Spain
      • 9.3.5.1 Market Trends
      • 9.3.5.2 Market Forecast
    • 9.3.6 Russia
      • 9.3.6.1 Market Trends
      • 9.3.6.2 Market Forecast
    • 9.3.7 Others
      • 9.3.7.1 Market Trends
      • 9.3.7.2 Market Forecast
  • 9.4 Latin America
    • 9.4.1 Brazil
      • 9.4.1.1 Market Trends
      • 9.4.1.2 Market Forecast
    • 9.4.2 Mexico
      • 9.4.2.1 Market Trends
      • 9.4.2.2 Market Forecast
    • 9.4.3 Others
      • 9.4.3.1 Market Trends
      • 9.4.3.2 Market Forecast
  • 9.5 Middle East and Africa
    • 9.5.1 Market Trends
    • 9.5.2 Market Breakup by Country
    • 9.5.3 Market Forecast

10 SWOT Analysis

  • 10.1 Overview
  • 10.2 Strengths
  • 10.3 Weaknesses
  • 10.4 Opportunities
  • 10.5 Threats

11 Value Chain Analysis

12 Porters Five Forces Analysis

  • 12.1 Overview
  • 12.2 Bargaining Power of Buyers
  • 12.3 Bargaining Power of Suppliers
  • 12.4 Degree of Competition
  • 12.5 Threat of New Entrants
  • 12.6 Threat of Substitutes

13 Price Analysis

14 Competitive Landscape

  • 14.1 Market Structure
  • 14.2 Key Players
  • 14.3 Profiles of Key Players
    • 14.3.1 3M Company
      • 14.3.1.1 Company Overview
      • 14.3.1.2 Product Portfolio
      • 14.3.1.3 Financials
      • 14.3.1.4 SWOT Analysis
    • 14.3.2 Biotene (GSK plc)
      • 14.3.2.1 Company Overview
      • 14.3.2.2 Product Portfolio
    • 14.3.3 Parnell Pharmaceuticals Inc.
      • 14.3.3.1 Company Overview
      • 14.3.3.2 Product Portfolio
    • 14.3.4 Quest Products LLC
      • 14.3.4.1 Company Overview
      • 14.3.4.2 Product Portfolio
    • 14.3.5 Saliwell Ltd
      • 14.3.5.1 Company Overview
      • 14.3.5.2 Product Portfolio
    • 14.3.6 Sun Pharmaceutical Industries Limited
      • 14.3.6.1 Company Overview
      • 14.3.6.2 Product Portfolio
      • 14.3.6.3 Financials
      • 14.3.6.4 SWOT Analysis
    • 14.3.7 West-Ward Pharmaceutical (Hikma Pharmaceuticals plc)
      • 14.3.7.1 Company Overview
      • 14.3.7.2 Product Portfolio