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市場調査レポート
商品コード
1722423
ハイスループットスクリーニング市場レポート:技術、製品・サービス、用途、エンドユーザー、地域別、2025年~2033年High-throughput Screening Market Report by Technology, Products and Services, Applications, End User, and Region 2025-2033 |
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ハイスループットスクリーニング市場レポート:技術、製品・サービス、用途、エンドユーザー、地域別、2025年~2033年 |
出版日: 2025年05月01日
発行: IMARC
ページ情報: 英文 146 Pages
納期: 2~3営業日
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世界のハイスループットスクリーニング市場規模は2024年に271億米ドルに達しました。今後、IMARC Groupは、市場は2033年までに507億米ドルに達し、2025年から2033年にかけて7.2%の成長率(CAGR)を示すと予測しています。3D細胞培養モデルの採用の増加、個別化医療スクリーニングアッセイの需要の増加、CRISPRベースのスクリーニング技術のアプリケーションの増加は、市場成長を促進する主な要因の一部です。
主な市場促進要因医薬品の製造に必要な時間を最小化するためにHTSの利用が増加していることが、主に市場の成長を促進しています。さらに、生命を脅かす様々な疾患の治療用新薬の開発も、HTS技術の需要を喚起しています。
主な市場動向:人工知能(AI)や機械学習(ML)などの先進技術とハイスループットスクリーニングとの統合による自動化と高速データ処理の促進は、市場の成長を増大させる重要な動向の一つです。
地域情勢別:ハイスループットスクリーニング市場予測レポートでは、地域別に市場を詳細に区分・分析しています。これには北米、アジア太平洋、欧州、ラテンアメリカ、中東・アフリカが含まれます。北米は、ハイスループットスクリーニング採用の増加、研究開発費の増加、コンビナトリアルケミストリーやゲノミクス分野の進歩などの要因により、ハイスループットスクリーニング市場で大きな市場シェアを占めると予測されています。
競合情勢:ハイスループットスクリーニング市場の主要企業には、Agilent Technologies Inc.、Aurora Biomed Inc.、Axxam S.p.A、Beckman Coulter Inc. (Danaher Corporation)、Bio-RAD Laboratories Inc.、Charles River Laboratories International Inc.、Corning Incorporated、Luminex Corporation (DiaSorin)、Perkinelmer Inc.、Sygnature Discovery、Tecan Group Ltd.、Thermo Fisher Scientificなどがあります。
課題と機会:ハイスループットスクリーニング市場における課題には、データ管理の複雑さや生理学的により適切なアッセイモデルの必要性が含まれる一方、機会としては、より効率的で予測的なスクリーニングプロセスのための自動化、人工知能、臓器チップシステムなどの技術の進歩にあります。
HTS施設の増加
生命を脅かすさまざまな疾患の治療に向けた新薬の開発が、主に市場成長の原動力となっています。さらに、医薬品製造に必要な時間を最短化するためのHTS利用の増加も市場成長に寄与しています。これに加えて、ハイスループットスクリーニング(HTS)施設の数が増加していることも、ハイスループットスクリーニング市場の最近の価格を刺激しています。これらのセンターの重要な利点の一つは、研究者、科学者、研究者等の間での知識の共有です。例えば、Columbia Genome Centerは、コロンビア大学の研究者コミュニティに質の高い分子スクリーニングサービスを提供しています。また、EU-open-screenとして知られる、米国国立衛生研究所(NIH)のプログラムに対応する欧州では、ケミカルバイオロジーに携わるすべての欧州企業にオープンアクセスを提供しています。ハイスループットスクリーニング(HTS)センターとの連携は、薬剤や標的、あるいはプロセス全体に関する有用な情報を提供することを目的としています。このように、オープンアクセスは知識共有のためのより良いプラットフォームを提供し、医薬品開発プロセスの加速に役立つため、今後数年間のハイスループットスクリーニング市場シェアを押し上げる可能性があります。
新規分子の開発増加
様々な感染症の流行は、新規分子やワクチンの開発を促しており、ハイスループットスクリーニング市場にも明るい見通しをもたらしています。さらに、医薬品製造中に様々な医薬品や分子を正確かつ迅速にスクリーニングする必要性が高まっているため、自動化されたハイスループットスクリーニング技術の採用が増加しています。さらに、高感度、自動化、サンプルの最小化、低バックグラウンドシグナルの検出能力など、ハイスループットスクリーニング法にはさまざまな利点があるため、さまざまな製薬会社や生物学的製剤会社がハイスループットスクリーニング法を採用するケースが増えており、これがハイスループットスクリーニング市場の需要を高めています。米国議会予算局が発表したデータによると、2021年、製薬業界が研究開発に費やした金額は、2019年が8,300万米ドルであったのに対し、2020年は世界全体で2,000億米ドル近くに上ることが確認されています。同様に、Danaher Corporationは、2020年の13億4,800万米ドルに対し、2021年には17億4,200万米ドルを研究開発に投資しました。また、Bio-Rad Laboratories Inc.は、2020年の8億30万米ドルに対し、2021年には8億7,960万米ドルを投資しました。このように、企業による研究開発への投資の増加は、ハイスループットスクリーニングアッセイに革新的な技術を採用する能力をさらに高め、それによって市場の成長を増大させています。
技術の進歩
ハイスループットスクリーニング(HTS)技術は、ロボット工学、自動化、データ解析、小型化における絶え間ない技術革新により、近年著しい進歩を遂げています。さらに、自動化とロボット工学の進歩は、HTSワークフローのスピードと効率を広範囲にわたって向上させています。自動化されたリキッドハンドリングシステム、プレートリーダー、ロボットプラットフォームは、反復作業を高精度とスループットで実行できるようになり、手作業による介入の必要性を減らしています。さらに、様々な主要バイオ企業も研究開発活動に投資し、改良されたHTSメソッドを導入しており、これがHTS市場の収益を押し上げると予想されます。例えば、2024年2月、ライフサイエンス分析技術の世界的リーダーであるSCIEXは、SLAS 2024でEcho MS+システムを発表しました。このシステムは、独自の音響放出質量分析技術とオープンポートインターフェース(OPI)サンプリングをSCIEX ZenoTOF 7600またはTriple Quad 6500+システムの機能と組み合わせることで、堅牢なハイスループットスクリーニングワークフローの拡張パネルを通じて正確な定性・定量結果を提供します。
The global high-throughput screening market size reached USD 27.1 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 50.7 Billion by 2033, exhibiting a growth rate (CAGR) of 7.2% during 2025-2033. The increased adoption of 3D cell culture models, growing demand for personalized medicine screening assays, and rising application of CRISPR-based screening techniques are some of the key factors driving the market growth.
Major Market Drivers: The increasing utilization of HTS for minimizing the time required for manufacturing a drug is primarily driving the growth of the market. Furthermore, the development of new medicines for treating various life-threatening diseases is also catalyzing the demand for HTS techniques.
Key Market Trends: Integration of advanced technologies, such as artificial intelligence (AI) and machine learning (ML) with high-throughput screening to facilitate automation and fast data processing is one of the significant trends, augmenting the growth of the market.
Geographical Landscape: The high-throughput screening market forecast report has provided a detailed breakup and analysis of the market based on the region. This includes North America, Asia Pacific, Europe, Latin America, and Middle East and Africa. North America is expected to hold a significant market share in the high-throughput screening market owing to factors such as the increasing adoption of high-throughput screening, rising research and development expenditure, and the growing advances in combinatorial chemistry and the field of genomics.
Competitive Landscape: Some of the leading high-throughput screening market companies include Agilent Technologies Inc., Aurora Biomed Inc., Axxam S.p.A, Beckman Coulter Inc. (Danaher Corporation), Bio-RAD Laboratories Inc., Charles River Laboratories International Inc. Corning Incorporated, Luminex Corporation (DiaSorin), Perkinelmer Inc., Sygnature Discovery, Tecan Group Ltd., and Thermo Fisher Scientific, among many others.
Challenges and Opportunities: Challenges in the high-throughput screening market include data management complexities and the need for more physiologically relevant assay models, while opportunities lie in advancing technologies like automation, artificial intelligence, and organ-on-a-chip systems for more efficient and predictive screening processes.
Increasing Number of HTS Facilities
The development of new medicines for treating various life-threatening diseases is primarily driving the growth of the market. Furthermore, the rise in the utilization of HTS for minimizing the time required for manufacturing a drug is also contributing to the market growth. In addition to this, the escalating number of high-throughput screening (HTS) facilities is also catalyzing the high-throughput screening market's recent prices. One of the significant advantages of these centers is knowledge sharing among investigators, scientists, researchers, etc. For instance, the Columbia Genome Center offers high-quality molecular screening services for investigators throughout the Columbia University research community. Also, the European counterpart of the National Institutes of Health (NIH) program, known as EU-open-screen, provides open access to all European companies engaged in chemical biology. The association of high-throughput screening (HTS) centers is intended to provide useful information about the drug or target or the entire process. Thus, open access provides a better platform for knowledge sharing and can help accelerate the drug development process, which may drive the high-throughput screening market share in the coming years.
Rising Development of Novel Molecules
The rising prevalence of various infectious diseases is prompting the development of novel molecules and vaccines, which in turn is creating a positive outlook for the high-throughput screening market. Moreover, the escalating need for precise and quick screening of various drugs and molecules during the manufacturing of a drug is resulting in an increased adoption of automated high-throughput screening techniques. Furthermore, various pharmaceutical and biologic firms are increasingly adopting high-throughput screening methods on account of their various advantages, such as high sensitivity, automation, minimization of the sample, and the ability to detect low background signals, which is bolstering the high-throughput screening market demand. According to the data published by the Congressional Budget Office, in 2021, it was observed that pharmaceutical industries spent nearly US$ 200 Billion on research and development in 2020 globally, compared to US$ 83 Million in 2019. Similarly, Danaher Corporation invested US$ 1,742 Million in its research and development in 2021, as compared to US$ 1,348 Million in 2020. In addition, Bio-Rad Laboratories Inc. invested US$ 879.6 Million in 2021 as compared to US$ 800.3 Million in 2020. Thus, the increasing investment in research and development by the companies further increases their capabilities to adopt innovative technologies in high throughput screening assays, thereby increasing the market growth.
Technological Advancements
High-throughput screening (HTS) techniques have seen significant advancements in recent years, driven by the continuous innovations in robotics, automation, data analysis, and miniaturization. Moreover, advances in automation and robotics are extensively increasing the speed and efficiency of HTS workflows. Automated liquid handling systems, plate readers, and robotic platforms can now perform repetitive tasks with high precision and throughput, reducing the need for manual intervention. Additionally, various leading biotech companies are also investing in research and development activities to introduce improved HTS methods which are anticipated to propel the high-throughput screening market revenue. For instance, in February 2024, SCIEX, a global leader in life science analytical technologies, launched the Echo MS+ system at SLAS 2024. The system couples proprietary Acoustic Ejection Mass Spectrometry technology and Open Port Interface (OPI) sampling with the capabilities of either the SCIEX ZenoTOF 7600 or Triple Quad 6500+ system to deliver precise qualitative and quantitative results through an expanded panel of robust high-throughput screening workflows.
The high-throughput screening market overview indicates that cell-based assays are increasingly being used by various pharmaceutical and biotech companies. Cell-based assays in high-throughput screening utilize live cells as the biological readout for compound testing, enabling the evaluation of drug candidates' effects on cellular function, viability, and phenotype in a high-throughput manner, often employed in drug discovery and toxicity screening. Fluorometric imaging plate reader assays have become the most used cell-based assays owing to visible results and their ability to test with the smallest of volumes. Besides this, ultra-high-throughput screening is the latest technology and is used for increased output in less time. A majority of companies are in a transition phase from 2D-cell cultures to 3D-cell cultures as 3D cells show more lifelike properties while testing in the natural environment and other cell-related manipulations, aided for drug design and discovery.
The high-throughput screening market report has provided a detailed breakup and analysis of the market based on the products and services. This includes instruments, reagents and kits, and services.
High-throughput screening relies on specialized instruments, such as automated liquid handlers, plate readers, and robotic platforms. These instruments enable the rapid handling, dispensing, and analysis of samples in microplate formats, thereby increasing the efficiency and throughput of screening experiments. Whereas reagents and kits that are used in high-throughput screening include compound libraries, biochemical assays, and detection reagents such as fluorescent probes or enzyme substrates. These are optimized for compatibility with automated systems and miniaturized assay formats, allowing for the screening of large compound libraries against specific biological targets or pathways.
Target identification and validation involves identifying and validating molecular targets (such as proteins, genes, or cellular pathways) that are implicated in a disease or biological process. Through various methods, including genomics, proteomics, and bioinformatics, potential targets are identified and then validated to ensure their relevance and draggability for further investigation. Whereas in primary and secondary screening large libraries of compounds are tested against a specific target or biological assay to identify initial hits that show activity or modulation. This method involves a more detailed characterization of hit compounds to confirm their activity, selectivity, and potency. Primary and secondary screening typically includes dose-response studies, counter-screens, and secondary assays to validate hits and prioritize them for lead optimization and preclinical development.
According to high-throughput screening market statistics by IMARC, the spending on research and development (R&D) by both pharmaceutical companies and government organizations has been increasing recently, which is anticipated to drive market growth over the forecast period. For instance, Danaher Corporation, a leading global life sciences and diagnostics innovator, invested US$ 1,742 Million in its research and development in 2021, as compared to US$ 1,348 Million in 2020. In addition, Bio-Rad Laboratories Inc. invested US$ 879.6 Million in 2021 as compared to US$ 800.3 Million in 2020. Thus, the huge investment by pharmaceuticals, biotech firms, and government institutions will continue to drive the market growth.
The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa.
North America is expected to hold a significant market share in the high-throughput screening market owing to various factors such as the increasing adoption of high-throughput screening, rising research and development expenditure, and the growing advances in combinatorial chemistry and the field of genomics. In addition to this, the presence of prominent market players in the region is also positively impacting the high-throughput screening market outlook. For instance, in August 2021, Becton, Dickinson, and Company launched a new, fully automated high-throughput diagnostic system using robotics and sample management software algorithms to set a new standard in automation for infectious disease molecular testing in core laboratories and other centralized laboratories in the United States. This launch made BD Onclarity HPV Assay with extended genotyping for the BD COR System available to the high-throughput labs for processing most cervical cancer screening specimens in the United States with persistent infection with human papillomavirus (HPV).
The market research report has provided a comprehensive analysis of the competitive landscape. Detailed profiles of all major companies have also been provided. Some of the key players in the market include:
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)
April 2024: Gordian Biotechnology introduced a high-throughput in vivo screening platform to discover therapies and better predict human outcomes for age-related diseases.
April 2024: Metrion Biosciences Limited and Enamine Ltd., announced that Metrion has enhanced its High Throughput Screening (HTS) services with the addition of access to Enamine's compound libraries.
February 2024: SCIEX, a global leader in life science analytical technologies, launched the Echo MS+ system at SLAS 2024. The system couples proprietary Acoustic Ejection Mass Spectrometry technology and Open Port Interface (OPI) sampling with the capabilities of either the SCIEX ZenoTOF 7600 or Triple Quad 6500+ system to deliver precise qualitative and quantitative results, through an expanded panel of robust high-throughput screening workflows.