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市場調査レポート
商品コード
1519698
がん免疫療法市場レポート:治療タイプ、用途、エンドユーザー、地域別、2024年~2032年Cancer Immunotherapy Market Report by Therapy Type, Application, End User, and Region 2024-2032 |
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がん免疫療法市場レポート:治療タイプ、用途、エンドユーザー、地域別、2024年~2032年 |
出版日: 2024年07月01日
発行: IMARC
ページ情報: 英文 143 Pages
納期: 2~3営業日
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世界のがん免疫療法の市場規模は2023年に1,189億米ドルに達しました。今後、IMARC Groupは、市場は2032年までに2,610億米ドルに達し、2024年から2032年の間に8.92%の成長率(CAGR)を示すと予測しています。がん患者数の増加、政府の積極的な取り組み、医療保険の幅広い利用可能性などが市場を牽引する主な要因となっています。
主な市場促進要因:バランスの悪い食事や有害物質の摂取を原因とするがん患者の増加は、市場の成長を促す主な要因の1つです。これに加えて、世界中の大衆の間で様々ながん治療の選択肢に対する認識が高まっていることも市場成長に寄与しています。
主な市場動向:医療保険が広く普及し、簡単に利用できるようになったことと、ヘルスケア支出の増加が、業界の投資家に有利な成長機会を提供しています。これに加えて、免疫療法のような副作用の少ない先進的な治療法への嗜好が高まっていることも、市場に明るい展望をもたらしています。
地域情勢別:地域レベルでは、市場は北米、アジア太平洋、欧州、ラテンアメリカ、中東・アフリカに分類され、現在は北米が世界市場を独占しています。
競合情勢:世界のがん免疫療法市場における主要企業には、Amgen Inc.、AstraZeneca plc、Bayer AG、Bristol-Myers Squibb Company、Eli Lilly and Company、F. Hoffmann-La Roche AG、GSK plc、Johnson &Johnson、Merck KGaA、Novartis AG、Pfizer Inc.、Sanofi S.A.、Seagen Inc.などがあります。
課題と機会:腫瘍の種類によって反応は異なります。しかし、特に低温の腫瘍では免疫療法が奏効しない場合があり、これは抵抗性の存在を示唆しています。従って、内在性または後天性の抵抗性の開拓は、免疫療法分野の市場参入者にとって大きな課題であると同時に重要な機会でもあります。
世界のがん免疫療法市場動向
がんの有病率の増加
世界中でがん患者数が増加していることが、がん免疫療法市場を牽引しています。国際がん研究機関(IARC)の推計によると、2020年のがん患者数は約1,929万人です。これらの症例は、2030年までに2,458万症例まで増加すると予測されています。このようながん患者の大幅な増加が、免疫療法のような効果的な治療ソリューションの需要を増大させています。GLOBOCANによると、2020年には米国だけで新たにがんと診断された症例は約228万1,658例、がんによる死亡は61万2,390例に上ります。これに加え、肺がんと乳がんは、個人の間で最もよく見られるがんの2つです。カナダがん協会(CCS)は、2020年には約2万9,800人のカナダ人が肺がんと診断され、新たながん患者の13%を占めると述べた。約21,200人のカナダ人が肺がんで死亡すると予想され、これは2020年のがん死亡者全体の25%を占める。このことは、効果的でより高度ながん免疫療法の必要性が高まっていることを示しています。このように、効果的かつ持続的ながん治療に対する需要の高まりは、市場全体に有利な成長機会をもたらすと予想されます。
新規免疫療法の承認の高まり
さまざまな新興国市場の主なプレーヤーは、より効果的で先進的な免疫療法を開発・導入するため、研究開発活動に積極的に投資しています。National Clinical Trials(NCT)Registryによると、2020年9月8日現在、免疫療法を用いたがん治療の開発のために世界中で1,000件以上の臨床試験が進行中です。さらに、各国の政府当局や関係規制当局は、新規免疫療法の承認プロセスを迅速化するためのイニシアチブをとっており、これが市場の成長をさらに促進すると予想されています。例えば、American Association for Cancer Researchが発表した記事によると、2023年7月、FDAはキザルチニブ(Vanflyta)を新たに診断された急性骨髄性白血病(AML)の異なる病期の治療薬として承認しました。キザルチニブは、AML症例の約3分の1でねじれるキナーゼであるFLT3に焦点を当てています。同様に2021年5月、米国FDAはアムジェンのルマクラス(ソトラシブ)を、変異を伴う局所進行性または転移性非小細胞肺がん(NSCLC)KRAS G12C患者の治療薬として承認しました。ルマクラスはNSCLCに対する最初で唯一の標的治療薬です。このような開発により、今後数年間はがん免疫療法市場の成長が促進されると予想されます。
製薬企業と研究機関のパートナーシップとコラボレーション
新製品を上市するために、大手企業によるさまざまな戦略的取り組みが行われており、市場全体に明るい見通しをもたらしています。例えば、2023年9月、Immatics社とModerna社は、オンコロジー治療薬を開発するために戦略的に提携しました。この提携には、イマティクスの治験薬PRAME203 TCRTとModernaが開発中のMARTE mRNAがんワクチンとの併用評価が含まれます。さらに、2023年8月、FBD Biologics LimitedとShanghai Henlius Biotech, Inc.は、新規免疫療法の開発を促進するための戦略的提携を締結しました。同様に、2023年12月、ドイツの研究機関であるBioMed Xは、日本の製薬会社である小野薬品工業株式会社との新たな共同研究プロジェクトを発表しました。同様に2023年12月、ドイツの研究機関BioMed Xは、日本の製薬会社である小野薬品工業株式会社と、好中球の抗腫瘍効果を活用した次世代免疫療法をデザインするための新たな共同研究プロジェクトを発表しました。アムジェン社、アストラゼネカ社、バイエル社、イーライリリー社など、いくつかの市場プレーヤーがM&A活動に関与しています。M&A活動を通じて、これらの企業は地理的範囲を拡大し、新しい領域に参入しています。その結果、予測期間中にがん免疫療法市場の収益が増加すると予測されます。
The global cancer immunotherapy market size reached US$ 118.9 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 261.0 Billion by 2032, exhibiting a growth rate (CAGR) of 8.92% during 2024-2032. The growing number of cancer cases, favorable government initiatives, and wide availability of medical insurance represent some of the key factors driving the market.
Major Market Drivers: The increasing cases of cancer on account of a poor balanced diet and consumption of toxic substances is one of the primary factors driving the growth of the market. In addition to this, the growing awareness about various cancer treatment options among the masses across the world is also contributing to the market growth.
Key Market Trends: The wide availability and easy access to medical insurance, along with the increasing healthcare expenditures, is offering lucrative growth opportunities to industry investors. In addition to this, the emerging preference for advanced treatment solutions with fewer side effects, like immunotherapy, is creating a positive outlook for the market.
Geographical Landscape: On a regional level, the market has been classified into North America, Asia-Pacific, Europe, Latin America, and Middle East and Africa, where North America currently dominates the global market.
Competitive Landscape: Some of the leading players in the global cancer immunotherapy market include Amgen Inc., AstraZeneca plc, Bayer AG, Bristol-Myers Squibb Company, Eli Lilly and Company, F. Hoffmann-La Roche AG, GSK plc, Johnson & Johnson, Merck KGaA, Novartis AG, Pfizer Inc., Sanofi S.A, and Seagen Inc., among others.
Challenges and Opportunities: Different tumor types respond differently. However, in some cases, especially cold tumors immunotherapy is unresponsive, suggesting the presence of resistance. Hence, the development of intrinsic or acquired resistance is a big challenge as well as a significant opportunity for the market players in the immunotherapy field.
Global Cancer Immunotherapy Market Trends
Increasing Prevalence of Cancer
The rising number of cancer cases across the world is primarily driving the market for cancer immunotherapies. The International Agency for Research on Cancer (IARC) estimated that, in the year 2020, there were about 19.29 million cancer cases. These cases are projected to increase to 24.58 million cases by 2030. Such a substantial growth in cancer cases is augmenting the demand for effective treatment solutions like immunotherapies. According to GLOBOCAN, in 2020, there were approximately 2,281,658 new cancer cases diagnosed and 612,390 deaths due to cancer alone in the United States. In addition to this, lung cancer and breast cancer are two of the most common cancers found among individuals. The Canadian Cancer Society (CCS) stated that in 2020, nearly 29,800 Canadians were diagnosed with lung cancer, which accounted for 13% of all new cancer cases. About 21,200 Canadians were expected to die from lung cancer, which represented 25% of all cancer deaths in 2020. This indicates an inflating need for effective and more advanced cancer immunotherapy. Thus, the increasing demand for effective and lasting cancer treatment is anticipated to offer lucrative growth opportunities to the overall market.
Rising Approval of Novel Immunotherapies
Various key market players are extensively investing in research and development activities to develop and introduce advanced and more effective immunotherapies. According to the National Clinical Trials (NCT) Registry, as of September 8, 2020, there were more than 1,000 ongoing clinical trials across the world for the development of cancer treatment with immune-based therapies. Moreover, government authorities and concerned regulators of numerous nations are taking initiatives to expedite the approval process of novel immunotherapies, which is anticipated to further catalyze the market growth. For instance, according to an article published by the American Association for Cancer Research, in July 2023, the FDA approved quizartinib (Vanflyta) for treating different phases of newly diagnosed acute myeloid leukemia (AML). Quizartinib focuses on FLT3, a kinase that goes twisted in about one-third of AML cases. Similarly, in May 2021, the US FDA approved Amgen's LUMAKRAS (Sotorasib) for the treatment of patients with KRAS G12C, which involves mutated locally advanced or metastatic non-small cell lung cancer (NSCLC). LUMAKRAS is the first and only targeted treatment for NSCLC. Such developments are expected to propel the cancer immunotherapy market growth in the coming years.
Partnerships and Collaborations between Pharmaceuticals and Research Institutions
Various Strategic initiatives are being undertaken by major players to launch new products, which is creating a positive outlook for the overall market. For instance, in September 2023, Immatics and Moderna strategically collaborated to develop Oncology Therapeutics. The collaboration includes an assessment of Immatics investigational PRAME203 TCRT in combination with the MARTE mRNA cancer vaccine being developed by Moderna. Moreover, in August 2023, FBD Biologics Limited and Shanghai Henlius Biotech, Inc. entered into a strategic collaboration to boost the development of new immunotherapies. Similarly, in December 2023, BioMed X, a German research institution, announced a new joint research project with Ono Pharmaceutical Co. Ltd, a Japanese pharmaceutical company, to design next-generation immunotherapies by leveraging the antitumor effects of neutrophils. Several market players, such as Amgen Inc., AstraZeneca plc, Bayer AG, and Eli Lilly and Company, are involved in merger and acquisition activities. Through M&A activity, these companies are expanding their geographic reach and entering new territories. This, in turn, is projected to bolster the cancer immunotherapy market revenue over the forecasted period.
IMARC Group provides an analysis of the key trends in each sub-segment of the market report, along with forecasts at the global, regional and country levels from 2024-2032. Our report has categorized the market based on therapy type, application and end user.
Monoclonal Antibodies
Cancer Vaccines
Checkpoint Inhibitors
Immunomodulators
Others
Currently, monoclonal antibodies hold the majority of the total market share
The report has provided a detailed breakup and analysis of the market based on the therapy type. This includes monoclonal antibodies, cancer vaccines, checkpoint inhibitors, immunomodulators, and others. According to the report, monoclonal antibodies represented the largest segment.
Increasing investment for research and development activities of monoclonal antibodies is opening new avenues for the growth of companies in the oncology therapeutics space. Monoclonal antibodies are extensively being studied for their therapeutic effects against various types of cancers. For instance, in August 2023, FDA approved Talvey to treat adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of treatment, including proteasome inhibitors, immunomodulatory agents and an antiCD38 monoclonal antibody.
Lung Cancer
Breast Cancer
Colorectal Cancer
Melanoma
Prostate Cancer
Head and Neck Cancer
Others
Among these, lung cancer currently exhibits a clear dominance in the market
A detailed breakup and analysis of the market based on the application has also been provided in the report. This includes lung cancer, breast cancer, colorectal cancer, melanoma, prostate cancer, head and neck cancer, and others. According to the report, lung cancer accounted for the largest market share.
According to cancer immunotherapy market overview, the lung cancer segment accounted for the largest revenue share in the market. This can be attributed to the increasing prevalence of lung malignancies, the escalating adoption of immunotherapy, and the presence of a robust pipeline of investigational candidates. Furthermore, rising product approval and new product launches also providing a positive outlook to the market. For instance, in November 2023, the US Food and Drug Administration (FDA) granted marketing authorizations to Augtyro (Bristol, Inc.) for the treatment of locally refractory or metastatic Non-Small Cell Lung Cancer (NSCLC) with Repotrectinib.
Hospitals
Cancer Research Centers
Clinics
Others
Hospitals account for the largest market share
A detailed breakup and analysis of the market based on the end user has also been provided in the report. This includes hospitals, cancer research centers, clinics, and others. According to the report, hospitals accounted for the largest market share.
Growing cases of cancer, increasing treatment rates, along with a large number of hospitals offering immunotherapies are contributing to a rise in the number of patients admitted to a hospital. To treat cancer, hospitals are increasingly utilizing immunotherapies. According to an article published by the National Cancer Institute, in April 2023, in the U.S. 25% of patients died in a hospital, with 62% hospitalized at least once in the last month of life for the cancer treatments.
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
North America currently dominates the global market.
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America (the United States and Canada) was the largest market for cancer immunotherapy.
The growth in the region can be attributed to the growing number of patients suffering from cancer, the rising development of bioinformatic tools, and favorable government initiatives. According to GLOBOCAN, in the US, there were an estimated 2,281,658 new cancer cases diagnosed and 612,390 deaths due to cancer in the year 2020. Moreover, the presence of key players in this region is also contributing to the growth of the market. According to an article published by Elsevier Ltd., in April 2023, the US National Cancer Institute published its expected national cancer plan, a roadmap, and calls to action on improving all stages of care for those suffering from cancer.
Amgen Inc.
AstraZeneca plc
Bayer AG
Bristol-Myers Squibb Company
Eli Lilly and Company
F. Hoffmann-La Roche AG
GSK plc
Johnson & Johnson
Merck KGaA
Novartis AG
Pfizer Inc.
Sanofi S.A
Seagen Inc.
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)
Global Cancer Immunotherapy Market Recent Developments
December 2023: Oxford University Hospitals launched a new mRNA cancer vaccine trial for patients with head and neck cancers.
December 2023: BioMed X, a German research institution announced a new joint research project with Ono Pharmaceutical Co. Ltd, a Japanese pharmaceutical company, to design next-generation immunotherapies by leveraging the antitumor effects of neutrophils.
July 2023: Spanish researchers at Cima University of Navarra developed a new immunotherapy combination for liver cancer. This therapy improves efficacy in animal models of hepatocellular carcinoma. This is a proof of concept that lays the foundations for the application of this treatment in patients with the most common liver cancer.