mRNA合成原料の市場規模、シェア、動向分析レポート：タイプ別、用途別、最終用途別、地域別、セグメント予測、2025年～2030年

mRNA合成原料市場の成長と動向：

Grand View Research, Inc.の最新レポートによると、mRNA合成原料の世界市場規模は、2025年から2030年にかけて5.78%のCAGRを記録し、2030年には23億米ドルに達すると推定されています。

市場成長を促進する主な要因としては、mRNA技術に対する学術的・産業的関心の高まり、mRNAワクチンの優位性、研究資金の増加などが挙げられます。さらに、RNA技術の治療用途の増加は、予測期間中にmRNA合成原料市場に有利な機会を提供すると予測されています。

COVID-19の大流行により、感染症と戦うための効率的なワクチン開発のためのmRNA合成原料の需要が高まっています。mRNAワクチンは、COVID-19を予防するための安全で効率的な方法です。さらに、mRNA COVID-19ワクチンに関連する利点は、世界中にワクチンを迅速に供給する製薬企業の関心を呼び起こしました。例えば、国立アレルギー感染症研究所とModerna, Inc.は2020年3月にmRNA-1273（NIAID）を相互開発しました。その結果、mRNAワクチンの使用量はCOVID-19パンデミックの際に大幅に増加しました。

さらに、Novartis、Alexion、AstraZeneca、Pfizer、Sanofi Pasteur、Shireなど、多くの大手製薬会社がmRNAベースの治療薬に取り組み始めました。例えば、2022年1月、ファイザー社とアキュイタス・セラピューティクス社との間の開発・オプション契約によると、ファイザー社はmRNA治療薬＆ワクチン開発のため、最大10のターゲットについてアキュイタス社のLNP技術をライセンスするオプションを持つことになります。そのため、mRNA合成原料の採用率は製薬・バイオ企業の間で高まっており、これが市場の成長をさらに後押ししています。

さらに、mRNA翻訳の一時的な性質と、細胞ゲノムへの外来物質の統合の欠如により、得られる細胞治療製品は、より従来のアプローチで得られるものよりも多くの利点があります。その利点のいくつかには、許容される製造手順のもとでの製造が容易であること、オンターゲットオフターマター効果による細胞毒性が低減されること、臨床的妥当性確認や規制当局による取り扱いが改善されることなどが含まれます。したがって、このような利点はmRNA治療薬の需要を高め、市場の成長をさらに押し上げると予想されます。

さらに、いくつかの疾患の治療と予防に関しても、mRNAベースの技術は非常に有望であることが証明されています。過去10年間の技術と科学的研究の飛躍的な進歩により、mRNAは実現可能な治療オプションとなり、半減期の短さや生得的な免疫原性など、その使用に関するいくつかの問題が解消されました。例えば、mRNA技術が進歩すれば、新しい養子免疫療法との融合により、最先端のキメラ抗原受容体T細胞の作製など、より安全で効率的な方法が生まれるかもしれないです。したがって、mRNA技術の進歩は市場成長の新たな道を開くと予測されます。

しかし、原料の高コストが調査期間中の市場の足かせとなる可能性があります。例えば、クリーンキャップAGのような原料の購入価格は、両ワクチンの製造時に発生する総原料費の約45%を占めています。さらに、承認プロセスに関する規制の枠組みは、バイオテクノロジー、製薬、医療技術業界において常に最も重大な阻害要因となっています。mRNA合成原料市場が大きな成長の可能性を秘める中国やインドなどの新興国では、治療分野に対する効果的な規制の枠組みやガイドラインが存在しないため、大規模な患者基盤の存在により、今後数年間の市場成長が阻害されると予想されます。

mRNA合成原料市場のレポートハイライト

• タイプ別では、キャッピング剤分野が予測期間中にCAGR 6.42%の最速成長が見込まれます。これは、キャッピング技術の進歩とバイオ医薬品産業および研究での用途によるものです。
• 用途別では、ワクチン製造分野が2024年に最大の収益シェアで世界業界を支配しました。これは、しばしば失敗しやすい細胞培養ベースの生産経路を利用する従来のワクチンと比較して、mRNAワクチンの迅速な生産に起因しています。
• 北米は、2024年に世界の業界を支配し、2023年には全体の収益の36.13%以上の最大シェアを占め、予測期間中最も高いCAGRで成長すると予測されています。
• 最終用途別では、バイオ医薬品の高い商業的成功と治療薬需要の急速な伸びにより、バイオ医薬品・製薬企業セグメントが2023年に最も高い収益シェアで市場を独占しました。

目次

第1章 調査手法と範囲

第2章 エグゼクティブサマリー

第3章 世界のmRNA合成原料市場の変数と動向

• 市場系統の見通し
  • 親市場の見通し
  • 関連/補助的な市場見通し。
• 市場力学
  • 市場促進要因分析
  • 市場抑制要因分析
• mRNA合成原料市場分析ツール
  • 業界分析- ポーターのファイブフォース分析
  • PESTEL分析
  • COVID-19の影響分析

第4章 世界のmRNA合成原料市場：タイプの推定・動向分析

• タイプセグメントダッシュボード
• 世界のmRNA合成原料市場変動分析
• 世界のmRNA合成原料市場規模と動向分析（タイプ別、2018～2030年）
• キャッピング剤
  • CleanCap試薬（TriLink BioTechnology）
  • ARCA（アンチリバースキャップアナログ）
  • その他
• ヌクレオチド
  • 修飾核酸
  • 天然核酸
• プラスミドDNA
• 酵素
  • ポリメラーゼ
  • RNase阻害剤
  • DNase
• その他

第5章 世界のmRNA合成原料市場：用途の推定・動向分析

• 用途セグメントダッシュボード
• 世界のmRNA合成原料市場の用途変動分析
• 世界のmRNA合成原料市場規模と動向分析（用途別、2018～2030年）
• ワクチン製造
• 治療薬製造
• その他

第6章 世界のmRNA合成原料市場：最終用途の推定・動向分析

• 最終用途セグメントダッシュボード
• 世界のmRNA合成原料市場の最終用途変動分析
• 世界のmRNA合成原料市場規模と動向分析（最終用途別、2018～2030年）
• バイオ医薬品および製薬会社
• CROとCMO
• 学術調査機関

第7章 mRNA合成原料市場：地域の推定・動向分析

• 地域ダッシュボード
• 市場規模と予測および動向分析、2018年から2030年
• 北米
  • 米国
  • カナダ
  • メキシコ
• 欧州
  • 英国
  • ドイツ
  • フランス
  • イタリア
  • スペイン
  • デンマーク
  • スウェーデン
  • ノルウェー
• アジア太平洋
  • 日本
  • 中国
  • インド
  • オーストラリア
  • タイ
  • 韓国
• ラテンアメリカ
  • ブラジル
  • アルゼンチン
• 中東・アフリカ
  • 南アフリカ
  • サウジアラビア
  • アラブ首長国連邦
  • クウェート

第8章 競合情勢

• 企業/競合の分類
• 戦略マッピング
• 企業市況分析、2024年
• 企業プロファイル/上場企業
  • F. Hoffmann-La Roche Ltd.
  • Jena Bioscience Gmbh
  • Merck KGaA
  • Yeasen Biotechnology（Shanghai）Co.,Ltd.
  • BOC Sciences
  • Thermo Fisher Scientific, Inc.
  • Maravai Lifesciences
  • New England Biolabs
  • Creative Biogene
  • Hongene

List of Tables

• Table 1 List of Secondary Sources
• Table 2 List of Abbreviations
• Table 3 Regulatory Framework
• Table 4 Global mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 5 Global mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 6 Global mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 7 Global mRNA synthesis raw materials Market, By Region, 2018 - 2030 (USD Million)
• Table 8 North America mRNA synthesis raw materials Market, By Country, 2018 - 2030 (USD Million)
• Table 9 North America mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 10 North America mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 11 North America mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 12 U.S. mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 13 U.S. mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 14 U.S. mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 15 Canada mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 16 Canada mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 17 Canada mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 18 Mexico mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 19 Mexico mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 20 Mexico mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 21 Europe mRNA synthesis raw materials Market, By Country, 2018 - 2030 (USD Million)
• Table 22 Europe mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 23 Europe mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 24 Europe mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 25 UK mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 26 UK mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 27 UK mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million),
• Table 28 Germany mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 29 Germany mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 30 Germany mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 31 France mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 32 France mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 33 France mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 34 Spain mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 35 Spain mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 36 Spain mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 37 Italy mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 38 Italy mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 39 Italy mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 40 Denmark mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 41 Denmark mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 42 Denmark mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 43 Norway mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 44 Norway mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 45 Norway mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 46 Sweden mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 47 Sweden mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 48 Sweden mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 49 Asia Pacific mRNA synthesis raw materials Market, By Country, 2018 - 2030 (USD Million)
• Table 50 Asia Pacific mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 51 Asia Pacific mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 52 Asia Pacific mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 53 China mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 54 China mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 55 China mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 56 Japan mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 57 Japan mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 58 Japan mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 59 India mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 60 India mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 61 India mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 62 South Korea mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 63 South Korea mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 64 South Korea mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 65 Australia mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 66 Australia mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 67 Australia mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 68 Thailand mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 69 Thailand mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 70 Thailand mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 71 Latin America mRNA synthesis raw materials Market, By Country, 2018 - 2030 (USD Million)
• Table 72 Latin America mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 73 Latin America mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 74 Latin America mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million),
• Table 75 Brazil mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 76 Brazil mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 77 Brazil mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 78 Argentina mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million),
• Table 79 Argentina mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 80 Argentina mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 81 MEA mRNA synthesis raw materials Market, By Country, 2018 - 2030 (USD Million)
• Table 82 MEA mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 83 MEA mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 84 MEA mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million),
• Table 85 South Africa mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 86 South Africa mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 87 South Africa mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 88 UAE mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 89 UAE mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 90 UAE mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 91 Saudi Arabia mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million),
• Table 92 Saudi Arabia mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 93 Saudi Arabia mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)
• Table 94 Kuwait mRNA synthesis raw materials Market, By Type, 2018 - 2030 (USD Million)
• Table 95 Kuwait mRNA synthesis raw materials Market, By Application, 2018 - 2030 (USD Million)
• Table 96 Kuwait mRNA synthesis raw materials Market, By End-user, 2018 - 2030 (USD Million)

List of Figures

• Fig. 1 mRNA synthesis raw materials market segmentation
• Fig. 2 Information procurement
• Fig. 3 Data analysis models
• Fig. 4 Market formulation and validation
• Fig. 5 Data validating & publishing
• Fig. 6 Market research process
• Fig. 7 Information procurement
• Fig. 8 Primary research
• Fig. 9 Market snapshot
• Fig. 10 Segment snapshot
• Fig. 11 Competitive landscape snapshot
• Fig. 12 mRNA synthesis raw materials market: Type outlook key takeaways
• Fig. 13 mRNA synthesis raw materials market: Type movement analysis
• Fig. 14 Global capping agents market, 2018 - 2030 (USD Million)
• Fig. 15 Global cleancap reagents market, 2018 - 2030 (USD Million)
• Fig. 16 Global ARCA (anti-reverse cap analog) market, 2018 - 2030 (USD Million)
• Fig. 17 Global others market, 2018 - 2030 (USD Million)
• Fig. 18 Global nucleotides market, 2018 - 2030 (USD Million)
• Fig. 19 Global modified nucleic acid market, 2018 - 2030 (USD Million)
• Fig. 20 Global N1-methylpseudouridine-triphosphate market, 2018 - 2030 (USD Million)
• Fig. 21 Global 5-Methylcytidine triphosphate (5mCTP) market, 2018 - 2030 (USD Million)
• Fig. 22 Global others market, 2018 - 2030 (USD Million)
• Fig. 23 Global natural nucleic acids market, 2018 - 2030 (USD Million)
• Fig. 24 Global adenine market, 2018 - 2030 (USD Million)
• Fig. 25 Global guanine market, 2018 - 2030 (USD Million)
• Fig. 26 Global cytosine market, 2018 - 2030 (USD Million)
• Fig. 27 Global uracil market, 2018 - 2030 (USD Million)
• Fig. 28 Global plasmid DNA market, 2018 - 2030 (USD Million)
• Fig. 29 Global enzymes mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
• Fig. 30 Global polymerase market, 2018 - 2030 (USD Million)
• Fig. 31 Global RNase inhibitor market, 2018 - 2030 (USD Million)
• Fig. 32 Global DNase market, 2018 - 2030 (USD Million)
• Fig. 33 Global others market, 2018 - 2030 (USD Million)
• Fig. 34 Global others mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
• Fig. 35 mRNA synthesis raw materials market: Application outlook and key takeaways
• Fig. 36 mRNA synthesis raw materials market: Application movement analysis
• Fig. 37 Global therapeutics production market, 2018 - 2030 (USD Million)
• Fig. 38 Global vaccine production market, 2018 - 2030 (USD Million)
• Fig. 39 Global other applications market, 2018 - 2030 (USD Million)
• Fig. 40 mRNA synthesis raw materials market: End-user outlook and key takeaways
• Fig. 41 mRNA synthesis raw materials market: End-user movement analysis
• Fig. 42 Global biopharmaceutical & pharmaceutical companies market, 2018 - 2030 (USD Million)
• Fig. 43 Global CROs & CMOs market, 2018 - 2030 (USD Million)
• Fig. 44 Global academic & research institutes market, 2018 - 2030 (USD Million)
• Fig. 45 Regional marketplace: Key takeaways
• Fig. 46 North America mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 47 Key country dynamics
• Fig. 48 U.S. mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 49 Key country dynamics
• Fig. 50 Canada mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 51 Key country dynamics
• Fig. 52 Mexico mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 53 Key country dynamics
• Fig. 54 Europe mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 55 Key country dynamics
• Fig. 56 Germany mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 57 Key country dynamics
• Fig. 58 UK mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 59 Key country dynamics
• Fig. 60 France mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 61 Key country dynamics
• Fig. 62 Italy mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 63 Key country dynamics
• Fig. 64 Spain mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 65 Market scenario
• Fig. 66 Key country dynamics
• Fig. 67 Denmark mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 68 Regulatory framework
• Fig. 69 Key country dynamics
• Fig. 70 Norway mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 71 Regulatory framework
• Fig. 72 Key country dynamics
• Fig. 73 Sweden mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 74 Regulatory framework
• Fig. 75 Asia Pacific mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 76 Key country dynamics
• Fig. 77 Japan mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 78 Key country dynamics
• Fig. 79 China mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 80 Key country dynamics
• Fig. 81 India mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 82 Key country dynamics
• Fig. 83 Australia mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 84 Key country dynamics
• Fig. 85 Thailand mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 86 Key country dynamics
• Fig. 87 South Korea mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 88 Latin America mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 89 Key country dynamics
• Fig. 90 Brazil mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 91 Key country dynamics
• Fig. 92 Argentina mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 93 MEA mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 94 Key country dynamics
• Fig. 95 South Africa mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 96 Key country dynamics
• Fig. 97 Saudi Arabia mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 98 Key country dynamics
• Fig. 99 UAE mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)
• Fig. 100 Key country dynamics
• Fig. 101 Kuwait mRNA synthesis raw materials market estimates and forecasts, 2018 - 2030 (USD Million)

mRNA Synthesis Raw Materials Market Growth & Trends:

The global mRNA synthesis raw materials market size is estimated to reach USD 2.30 billion by 2030, registering a CAGR of 5.78% from 2025 to 2030, according to a new report by Grand View Research, Inc. The major factors driving the market growth include growing academic and industrial interest in mRNA technology, the advantages of mRNA vaccines, and increasing funding for research. In addition, the increasing therapeutic applications of RNA technology are projected to offer lucrative opportunities for the mRNA synthesis raw materials market during the forecast period.

The COVID-19 pandemic has increased the demand for mRNA synthesis raw materials for developing an efficient vaccine to battle infectious diseases. mRNA vaccines are a safe and efficient method for preventing COVID-19. In addition, the advantages associated with the mRNA COVID-19 vaccines have sparked the attention of pharmaceutical businesses in delivering vaccines swiftly across the globe. For instance, the National Institute of Allergy and Infectious Diseases and Moderna, Inc. mutually developed the mRNA-1273 (NIAID) in March 2020. As a result, the usage of mRNA vaccines increased significantly during the COVID-19 pandemic.

Furthermore, many major pharmaceutical firms have started working on mRNA-based therapeutics, including Novartis, Alexion, AstraZeneca, Pfizer, Sanofi Pasteur, and Shire. For instance, in January 2022, according to a development and option agreement between Pfizer Inc. and Acuitas Therapeutics, Pfizer will have the option to license Acuitas' LNP technology for up to 10 targets for the development of mRNA therapeutics & vaccines. Therefore, the adoption rate of mRNA synthesis raw materials has increased among pharma & biotech companies, which further fuels the market growth.

Moreover, due to the temporary nature of mRNA translation and lack of integration of the foreign material into the cell's genome, the resulting cellular therapeutic product has a number of benefits over the one obtained by a more conventional approach. Some of the advantages include easier production under acceptable manufacturing procedures, reduced cytotoxicity from on-target off-tumor effects, and better clinical validation and regulatory treatment. Thus, such advantages are expected to increase the demand for mRNA therapeutics and further boost market growth.

Additionally, regarding the treatment and prevention of several diseases, mRNA-based technologies have been proven to be incredibly promising. Tremendous advances in technology and scientific study over the past ten years have made mRNA a feasible therapeutic option, eliminating some of the problems with its use, such as its brief half-life and innate immunogenicity. For instance, as mRNA technology advances, its fusion with new adoptive immunotherapies may result in safer and more efficient methods, such as the creation of cutting-edge chimeric antigen receptor T-cells. Therefore, advancements in mRNA technology are projected to open new avenues for market growth.

However, the high cost of raw materials may impede the market during the study period. For instance, the purchase price of raw materials, such as CleanCap AG, accounts for around 45% of the total raw material costs incurred while producing both vaccines. In addition, the regulatory framework pertaining to approval processes has always been the most critical restraining factor in the biotechnology, pharmaceutical, and medical technology industry. The absence of effective regulatory framework/guidelines for the therapeutic sector in developing countries such as China and India, where the mRNA synthesis raw materials market holds great growth potential due to the presence of a large patient base, is anticipated to impede the market growth in the coming years.

mRNA Synthesis Raw Materials Market Report Highlights:

• By type, the capping agents segment is expected to grow with the fastest CAGR of 6.42% over the forecast period, owing to the advancements in the capping technology and their applications in the biopharma industry and research.
• By application, the vaccine production segment dominated the global industry with the largest revenue share in 2024. This can be attributed to the rapid production of mRNA vaccines compared to the conventional vaccines that utilize cell-culture-based production paths, which are often prone to failure.
• North America dominated the global industry in 2024 and accounted for the largest share of more than 36.13% of the overall revenue in 2023, and is expected to grow at the highest CAGR over the forecast period.
• By end-use, the biopharmaceutical and pharmaceutical companies segment dominated the market with the highest revenue share in 2023, due to the high commercial success of biopharmaceuticals and rapid growth in demand for therapeutics.

Table of Contents

Chapter 1. Methodology and Scope

• 1.1. Market Segmentation and Scope
• 1.2. Market Definitions
  • 1.2.1. Type Segment
  • 1.2.2. Application Segment
  • 1.2.3. End Use Segment
• 1.3. Information analysis
• 1.4. Market formulation & data visualization
• 1.5. Data validation & publishing
• 1.6. Information Procurement
  • 1.6.1. Primary Research
• 1.7. Information or Data Analysis
• 1.8. Market Formulation & Validation
• 1.9. Market Model
• 1.10. Objectives

Chapter 2. Executive Summary

• 2.1. Market Outlook
• 2.2. Segment Snapshot
• 2.3. Competitive Insights Landscape

Chapter 3. Global mRNA Synthesis Raw Materials Market Variables & Trends

• 3.1. Market Lineage Outlook
  • 3.1.1. Parent market outlook
  • 3.1.2. Related/ancillary market outlook.
• 3.2. Market Dynamics
  • 3.2.1. Market driver analysis
  • 3.2.2. Market restraint analysis
• 3.3. mRNA Synthesis Raw Materials Market Analysis Tools
  • 3.3.1. Industry Analysis - Porter's
  • 3.3.2. PESTEL Analysis
  • 3.3.3. COVID-19 Impact Analysis

Chapter 4. Global mRNA Synthesis Raw Materials Market: Type Estimates & Trend Analysis

• 4.1. Type Segment Dashboard
• 4.2. Global mRNA Synthesis Raw Materials Market Type Movement Analysis
• 4.3. Global mRNA Synthesis Raw Materials Market Size & Trend Analysis, by Type, 2018 to 2030 (USD Million)
• 4.4. Capping Agents
  • 4.4.1. Capping agents market estimates and forecasts 2018 to 2030 (USD Million)
  • 4.4.2. CleanCap Reagents (TriLink BioTechnology)
    • 4.4.2.1. CleanCap reagents (TriLink BioTechnology) market estimates and forecasts 2018 to 2030 (USD Million)
  • 4.4.3. ARCA (Anti-Reverse Cap Analog)
    • 4.4.3.1. ARCA (Anti-Reverse Cap Analog) market estimates and forecasts 2018 to 2030 (USD Million)
  • 4.4.4. Others
    • 4.4.4.1. Others market estimates and forecasts 2018 to 2030 (USD Million)
• 4.5. Nucleotides
  • 4.5.1. Nucleotides market estimates and forecasts 2018 to 2030 (USD Million)
  • 4.5.2. Modified nucleic acids
    • 4.5.2.1. Modified nucleic acids market estimates and forecasts 2018 to 2030 (USD Million)
    • 4.5.2.2. N1-methylpseudouridine-triphosphate
      • 4.5.2.2.1. N1-methylpseudouridine-triphosphate market estimates and forecasts 2018 to 2030 (USD Million)
    • 4.5.2.3. 5-Methylcytidine triphosphate (5mCTP)
      • 4.5.2.3.1. 5-Methylcytidine triphosphate (5mCTP) market estimates and forecasts 2018 to 2030 (USD Million)
    • 4.5.2.4. Others
      • 4.5.2.4.1. Others market estimates and forecasts 2018 to 2030 (USD Million)
  • 4.5.3. Natural nucleic acids
    • 4.5.3.1. Natural nucleic acids market estimates and forecasts 2018 to 2030 (USD Million)
    • 4.5.3.2. Adenine
      • 4.5.3.2.1. Adenine-triphosphate market estimates and forecasts 2018 to 2030 (USD Million)
    • 4.5.3.3. Guanine
      • 4.5.3.3.1. Guanine market estimates and forecasts 2018 to 2030 (USD Million)
    • 4.5.3.4. Cytosine
      • 4.5.3.4.1. Cytosine market estimates and forecasts 2018 to 2030 (USD Million)
    • 4.5.3.5. Uracil
      • 4.5.3.5.1. Uracil market estimates and forecasts 2018 to 2030 (USD Million)
• 4.6. Plasmid DNA
  • 4.6.1. Plasmid DNA market estimates and forecasts 2018 to 2030 (USD Million)
• 4.7. Enzymes
  • 4.7.1. Enzymes market estimates and forecasts 2018 to 2030 (USD Million)
  • 4.7.2. Polymerase
    • 4.7.2.1. Polymerase market estimates and forecasts 2018 to 2030 (USD Million)
  • 4.7.3. RNase Inhibitor
    • 4.7.3.1. RNase inhibitor market estimates and forecasts 2018 to 2030 (USD Million)
  • 4.7.4. DNase
    • 4.7.4.1. DNase market estimates and forecasts 2018 to 2030 (USD Million)
• 4.8. Others
  • 4.8.1. Others market estimates and forecasts 2018 to 2030 (USD Million)

Chapter 5. Global mRNA Synthesis Raw Materials Market: Application Estimates & Trend Analysis

• 5.1. Application Segment Dashboard
• 5.2. Global mRNA Synthesis Raw Materials Market Application Movement Analysis
• 5.3. Global mRNA Synthesis Raw Materials Market Size & Trend Analysis, by Application, 2018 to 2030 (USD Million)
• 5.4. Vaccine Production
  • 5.4.1. Vaccine production market estimates and forecasts 2018 to 2030 (USD Million)
• 5.5. Therapeutics Production
  • 5.5.1. Therapeutics production market estimates and forecasts 2018 to 2030 (USD Million)
• 5.6. Others
  • 5.6.1. Others market estimates and forecasts 2018 to 2030 (USD Million)

Chapter 6. Global mRNA Synthesis Raw Materials Market: End Use Estimates & Trend Analysis

• 6.1. End Use Segment Dashboard
• 6.2. Global mRNA Synthesis Raw Materials Market End Use Movement Analysis
• 6.3. Global mRNA Synthesis Raw Materials Market Size & Trend Analysis, by End Use, 2018 to 2030 (USD Million)
• 6.4. Biopharmaceutical & Pharmaceutical Companies
  • 6.4.1. Biopharmaceutical & pharmaceutical companies market estimates and forecasts 2018 to 2030 (USD Million)
• 6.5. CROs & CMOs
  • 6.5.1. CROs & CMOs market estimates and forecasts 2018 to 2030 (USD Million)
• 6.6. Academic & Research Institutes
  • 6.6.1. Academic & research institutes market estimates and forecasts 2018 to 2030 (USD Million)

Chapter 7. MRNA Synthesis Raw Materials Market: Regional Estimates & Trend Analysis

• 7.1. Regional Dashboard
• 7.2. Market Size & Forecasts and Trend Analysis, 2018 to 2030
• 7.3. North America
  • 7.3.1. North America MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.3.2. U.S.
    • 7.3.2.1. Key Country Dynamics
    • 7.3.2.2. Competitive Scenario
    • 7.3.2.3. Regulatory Framework
    • 7.3.2.4. U.S. MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.3.3. Canada
    • 7.3.3.1. Key Country Dynamics
    • 7.3.3.2. Competitive Scenario
    • 7.3.3.3. Regulatory Framework
    • 7.3.3.4. Canada MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.3.4. Mexico
    • 7.3.4.1. Key Country Dynamics
    • 7.3.4.2. Competitive Scenario
    • 7.3.4.3. Regulatory Framework
    • 7.3.4.4. Mexico MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
• 7.4. Europe
  • 7.4.1. Europe MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4.2. UK
    • 7.4.2.1. Key Country Dynamics
    • 7.4.2.2. Competitive Scenario
    • 7.4.2.3. Regulatory Framework
    • 7.4.2.4. UK MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4.3. Germany
    • 7.4.3.1. Key Country Dynamics
    • 7.4.3.2. Competitive Scenario
    • 7.4.3.3. Regulatory Framework
    • 7.4.3.4. Germany MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4.4. France
    • 7.4.4.1. Key Country Dynamics
    • 7.4.4.2. Competitive Scenario
    • 7.4.4.3. Regulatory Framework
    • 7.4.4.4. France MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4.5. Italy
    • 7.4.5.1. Key Country Dynamics
    • 7.4.5.2. Competitive Scenario
    • 7.4.5.3. Regulatory Framework
    • 7.4.5.4. Italy MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4.6. Spain
    • 7.4.6.1. Key Country Dynamics
    • 7.4.6.2. Competitive Scenario
    • 7.4.6.3. Regulatory Framework
    • 7.4.6.4. Spain MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4.7. Denmark
    • 7.4.7.1. Key Country Dynamics
    • 7.4.7.2. Competitive Scenario
    • 7.4.7.3. Regulatory Framework
    • 7.4.7.4. Denmark MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4.8. Sweden
    • 7.4.8.1. Key Country Dynamics
    • 7.4.8.2. Competitive Scenario
    • 7.4.8.3. Regulatory Framework
    • 7.4.8.4. Sweden MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.4.9. Norway
    • 7.4.9.1. Key Country Dynamics
    • 7.4.9.2. Competitive Scenario
    • 7.4.9.3. Regulatory Framework
    • 7.4.9.4. Norway MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
• 7.5. Asia Pacific
  • 7.5.1. Asia Pacific MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.5.2. Japan
    • 7.5.2.1. Key Country Dynamics
    • 7.5.2.2. Competitive Scenario
    • 7.5.2.3. Regulatory Framework
    • 7.5.2.4. Japan MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.5.3. China
    • 7.5.3.1. Key Country Dynamics
    • 7.5.3.2. Competitive Scenario
    • 7.5.3.3. Regulatory Framework
    • 7.5.3.4. China MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.5.4. India
    • 7.5.4.1. Key Country Dynamics
    • 7.5.4.2. Competitive Scenario
    • 7.5.4.3. Regulatory Framework
    • 7.5.4.4. India MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.5.5. Australia
    • 7.5.5.1. Key Country Dynamics
    • 7.5.5.2. Competitive Scenario
    • 7.5.5.3. Regulatory Framework
    • 7.5.5.4. Australia MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.5.6. Thailand
    • 7.5.6.1. Key Country Dynamics
    • 7.5.6.2. Competitive Scenario
    • 7.5.6.3. Regulatory Framework
    • 7.5.6.4. Thailand MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.5.7. South Korea
    • 7.5.7.1. Key Country Dynamics
    • 7.5.7.2. Competitive Scenario
    • 7.5.7.3. Regulatory Framework
    • 7.5.7.4. South Korea MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
• 7.6. Latin America
  • 7.6.1. Latin America MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.6.2. Brazil
    • 7.6.2.1. Key Country Dynamics
    • 7.6.2.2. Competitive Scenario
    • 7.6.2.3. Regulatory Framework
    • 7.6.2.4. Brazil MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.6.3. Argentina
    • 7.6.3.1. Key Country Dynamics
    • 7.6.3.2. Competitive Scenario
    • 7.6.3.3. Regulatory Framework
    • 7.6.3.4. Argentina MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
• 7.7. MEA
  • 7.7.1. MEA MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.7.2. South Africa
    • 7.7.2.1. Key Country Dynamics
    • 7.7.2.2. Competitive Scenario
    • 7.7.2.3. Regulatory Framework
    • 7.7.2.4. South Africa MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.7.3. Saudi Arabia
    • 7.7.3.1. Key Country Dynamics
    • 7.7.3.2. Competitive Scenario
    • 7.7.3.3. Regulatory Framework
    • 7.7.3.4. Saudi Arabia MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.7.4. UAE
    • 7.7.4.1. Key Country Dynamics
    • 7.7.4.2. Competitive Scenario
    • 7.7.4.3. Regulatory Framework
    • 7.7.4.4. UAE MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)
  • 7.7.5. Kuwait
    • 7.7.5.1. Key Country Dynamics
    • 7.7.5.2. Competitive Scenario
    • 7.7.5.3. Regulatory Framework
    • 7.7.5.4. Kuwait MRNA Synthesis Raw Materials Market Estimates and Forecasts, 2018 - 2030 (USD Million)

Chapter 8. Competitive Landscape

• 8.1. Company/Competition Categorization
• 8.2. Strategy Mapping
• 8.3. Company Market Position Analysis, 2024
• 8.4. Company Profiles/Listing
  • 8.4.1. F. Hoffmann - La Roche Ltd.
    • 8.4.1.1. Company overview
    • 8.4.1.2. Financial performance
    • 8.4.1.3. Product benchmarking
    • 8.4.1.4. Strategic initiatives
  • 8.4.2. Jena Bioscience Gmbh
    • 8.4.2.1. Company overview
    • 8.4.2.2. Financial performance
    • 8.4.2.3. Product benchmarking
    • 8.4.2.4. Strategic initiatives
  • 8.4.3. Merck KGaA
    • 8.4.3.1. Company overview
    • 8.4.3.2. Financial performance
    • 8.4.3.3. Product benchmarking
    • 8.4.3.4. Strategic initiatives
  • 8.4.4. Yeasen Biotechnology (Shanghai) Co.,Ltd.
    • 8.4.4.1. Company overview
    • 8.4.4.2. Financial performance
    • 8.4.4.3. Product benchmarking
    • 8.4.4.4. Strategic initiatives
  • 8.4.5. BOC Sciences
    • 8.4.5.1. Company overview
    • 8.4.5.2. Financial performance
    • 8.4.5.3. Product benchmarking
    • 8.4.5.4. Strategic initiatives
  • 8.4.6. Thermo Fisher Scientific, Inc.
    • 8.4.6.1. Company overview
    • 8.4.6.2. Financial performance
    • 8.4.6.3. Product benchmarking
    • 8.4.6.4. Strategic initiatives
  • 8.4.7. Maravai Lifesciences
    • 8.4.7.1. Company overview
    • 8.4.7.2. Financial performance
    • 8.4.7.3. Product benchmarking
    • 8.4.7.4. Strategic initiatives
  • 8.4.8. New England Biolabs
    • 8.4.8.1. Company overview
    • 8.4.8.2. Financial performance
    • 8.4.8.3. Product benchmarking
    • 8.4.8.4. Strategic initiatives
  • 8.4.9. Creative Biogene
    • 8.4.9.1. Company overview
    • 8.4.9.2. Financial performance
    • 8.4.9.3. Product benchmarking
    • 8.4.9.4. Strategic initiatives
  • 8.4.10. Hongene
    • 8.4.10.1. Company overview
    • 8.4.10.2. Financial performance
    • 8.4.10.3. Product benchmarking
    • 8.4.10.4. Strategic initiatives