Product Code: GVR-4-68040-595-7
Ultomiris Drug Market Summary
The global ultomiris drug market size was estimated at USD 3.92 billion in 2024 and is projected to reach USD 18.03 billion by 2030, growing at a CAGR of 28.47% from 2025 to 2030. The global Ultomiris (ravulizumab) drug industry is experiencing strong momentum due to the rising demand for long-acting treatments in rare disorders.
Compared to its predecessor, Soliris, the drug's extended dosing interval offers convenience and improved patient compliance. This has increased preference among healthcare providers managing conditions such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). Alexion reported that over 70% of PNH patients had transitioned to Ultomiris from Soliris in major markets, including the U.S. and EU. The transition from older complement inhibitors to ravulizumab contributes to overall market expansion.
Growth is further fueled by its expanding clinical utility across new indications such as generalized myasthenia gravis (gMG). For instance, in September 2022, Ultomiris received approval from the European Commission to treat adult patients with anti-acetylcholine receptor antibody-positive gMG, strengthening its position in the neurology segment.
The rising incidence of rare autoimmune and hematologic conditions is also a major factor driving demand for Ultomiris. Improved diagnostic tools and updated clinical guidelines have identified eligible patient populations earlier. For instance, in March 2024, the FDA granted priority review to Ultomiris for its potential use in treating neuromyelitis optica spectrum disorder (NMOSD), highlighting its pipeline strength. Strategic marketing efforts and partnerships by AstraZeneca and Alexion have helped expand awareness among clinicians and treatment centers. These combined elements shape a favorable environment for sustained revenue growth through 2030.
Global Ultomiris Drug Market Report Segmentation
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global Ultomiris (ravulizumab) drug market report based on indication, end use, distribution channel, and region:
- Indication Outlook (Revenue, USD Million, 2018 - 2030)
- Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Atypical Hemolytic Uremic Syndrome (aHUS)
- Generalized Myasthenia Gravis (gMG)
- Neuromyelitis Optica Spectrum Disorder (NMOSD)
- End Use Outlook (Revenue, USD Million, 2018 - 2030)
- Adult
- Pediatric
- Distribution Channel Outlook (Revenue, USD Million, 2018 - 2030)
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
- Regional Outlook (Revenue, USD Million, 2018 - 2030)
- North America
- Europe
- UK
- Germany
- France
- Italy
- Spain
- Denmark
- Sweden
- Norway
- Asia Pacific
- Japan
- China
- India
- Australia
- South Korea
- Thailand
- Latin America
- Middle East & Africa
- South Africa
- Saudi Arabia
- UAE
- Kuwait
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation & Scope
- 1.2. Segment Definitions
- 1.2.1. Indication
- 1.2.2. End Use
- 1.2.3. Distribution Channel
- 1.3. Estimates and Forecast Timeline
- 1.4. Research Methodology
- 1.5. Information Procurement
- 1.5.1. Purchased Database
- 1.5.2. GVR's Internal Database
- 1.5.3. Secondary Sources
- 1.5.4. Primary Research
- 1.6. Information Analysis
- 1.6.1. Data Analysis Models
- 1.7. Market Formulation & Data Visualization
- 1.8. Model Details
- 1.8.1. Commodity Flow Analysis
- 1.9. List of Secondary Sources
- 1.10. Objectives
Chapter 2. Executive Summary
- 2.1. Market Snapshot
- 2.2. Segment Snapshot
- 2.3. Competitive Landscape Snapshot
Chapter 3. Ultomiris (Ravulizumab) Drug Market Variables, Trends, & Scope
- 3.1. Market Lineage Outlook
- 3.2. Market Dynamics
- 3.2.1. Market Driver Analysis
- 3.2.2. Market Restraint Analysis
- 3.3. Business Environment Analysis
- 3.3.1. Industry Analysis - Porter's Five Forces Analysis
- 3.3.1.1. Supplier Power
- 3.3.1.2. Buyer Power
- 3.3.1.3. Substitution Threat
- 3.3.1.4. Threat of New Entrants
- 3.3.1.5. Competitive Rivalry
- 3.3.2. PESTLE Analysis
- 3.3.3. Pipeline Analysis
- 3.3.4. Patent Expiry Analysis
- 3.3.5. Pricing Analysis
Chapter 4. Ultomiris (Ravulizumab) Drug Market: Indication Business Analysis
- 4.1. Indication Market Share, 2024 & 2030
- 4.2. Indication Segment Dashboard
- 4.3. Market Size & Forecasts and Trend Analysis, by Indication, 2018 to 2030 (USD Million)
- 4.4. Paroxysmal Nocturnal Hemoglobinuria (PNH)
- 4.4.1. Paroxysmal Nocturnal Hemoglobinuria (PNH) Market, 2018 - 2030 (USD Million)
- 4.5. Atypical Hemolytic Uremic Syndrome (aHUS)
- 4.5.1. Atypical Hemolytic Uremic Syndrome (aHUS) Market, 2018 - 2030 (USD Million)
- 4.6. Generalized Myasthenia Gravis (gMG)
- 4.6.1. Generalized Myasthenia Gravis (gMG) Market, 2018 - 2030 (USD Million)
- 4.7. Neuromyelitis Optica Spectrum Disorder (NMOSD)
- 4.7.1. Neuromyelitis Optica Spectrum Disorder (NMOSD) Market, 2018 - 2030 (USD Million)
Chapter 5. Ultomiris (Ravulizumab) Drug Market: End Use Business Analysis
- 5.1. End Use Market Share, 2024 & 2030
- 5.2. End Use Segment Dashboard
- 5.3. Market Size & Forecasts and Trend Analysis, by End Use, 2018 to 2030 (USD Million)
- 5.4. Adult
- 5.4.1. Adult Market, 2018 - 2030 (USD Million)
- 5.5. Pediatric
- 5.5.1. Pediatric Market, 2018 - 2030 (USD Million)
Chapter 6. Ultomiris (Ravulizumab) Drug Market: Distribution Channel Business Analysis
- 6.1. Distribution Channel Market Share, 2024 & 2030
- 6.2. Distribution Channel Segment Dashboard
- 6.3. Market Size & Forecasts and Trend Analysis, by Distribution Channel, 2018 to 2030 (USD Million)
- 6.4. Hospital Pharmacies
- 6.4.1. Hospital Pharmacies Market, 2018 - 2030 (USD Million)
- 6.5. Retail Pharmacies
- 6.5.1. Retail Pharmacies Market, 2018 - 2030 (USD Million)
- 6.6. Online Pharmacies
- 6.6.1. Online Pharmacies Market, 2018 - 2030 (USD Million)
Chapter 7. Ultomiris (Ravulizumab) Drug Market: Regional Estimates & Trend Analysis
- 7.1. Regional Market Share Analysis, 2024 & 2030
- 7.2. Regional Market Dashboard
- 7.3. Market Size & Forecasts Trend Analysis, 2018 to 2030:
- 7.4. North America
- 7.4.1. North America Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, By Country, 2018 - 2030 (USD Million)
- 7.4.2. U.S.
- 7.4.2.1. Key Country Dynamics
- 7.4.2.2. Target Disease Prevalence
- 7.4.2.3. Regulatory Framework
- 7.4.2.4. Reimbursement Framework
- 7.4.2.5. U.S. Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.4.3. Canada
- 7.4.3.1. Key Country Dynamics
- 7.4.3.2. Target Disease Prevalence
- 7.4.3.3. Regulatory Framework
- 7.4.3.4. Reimbursement Framework
- 7.4.3.5. U.S. Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.4.4. Mexico
- 7.4.4.1. Key Country Dynamics
- 7.4.4.2. Target Disease Prevalence
- 7.4.4.3. Regulatory Framework
- 7.4.4.4. Reimbursement Framework
- 7.4.4.5. Mexico Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5. Europe
- 7.5.1. Europe Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.2. UK
- 7.5.2.1. Key Country Dynamics
- 7.5.2.2. Target Disease Prevalence
- 7.5.2.3. Regulatory Framework
- 7.5.2.4. Reimbursement Framework
- 7.5.2.5. Uk Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.3. Germany
- 7.5.3.1. Key Country Dynamics
- 7.5.3.2. Target Disease Prevalence
- 7.5.3.3. Regulatory Framework
- 7.5.3.4. Reimbursement Framework
- 7.5.3.5. Germany Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.4. France
- 7.5.4.1. Key Country Dynamics
- 7.5.4.2. Target Disease Prevalence
- 7.5.4.3. Regulatory Framework
- 7.5.4.4. Reimbursement Framework
- 7.5.4.5. France Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.5. Italy
- 7.5.5.1. Key Country Dynamics
- 7.5.5.2. Target Disease Prevalence
- 7.5.5.3. Regulatory Framework
- 7.5.5.4. Reimbursement Framework
- 7.5.5.5. Italy Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.6. Spain
- 7.5.6.1. Key Country Dynamics
- 7.5.6.2. Target Disease Prevalence
- 7.5.6.3. Regulatory Framework
- 7.5.6.4. Reimbursement Framework
- 7.5.6.5. Spain Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.7. Denmark
- 7.5.7.1. Key Country Dynamics
- 7.5.7.2. Target Disease Prevalence
- 7.5.7.3. Regulatory Framework
- 7.5.7.4. Reimbursement Framework
- 7.5.7.5. Denmark Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.8. Sweden
- 7.5.8.1. Key Country Dynamics
- 7.5.8.2. Target Disease Prevalence
- 7.5.8.3. Regulatory Framework
- 7.5.8.4. Reimbursement Framework
- 7.5.8.5. Sweden Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.9. Norway
- 7.5.9.1. Key Country Dynamics
- 7.5.9.2. Target Disease Prevalence
- 7.5.9.3. Regulatory Framework
- 7.5.9.4. Reimbursement Framework
- 7.5.9.5. Norway Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6. Asia Pacific
- 7.6.1. Asia Pacific Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.2. Japan
- 7.6.2.1. Key Country Dynamics
- 7.6.2.2. Target Disease Prevalence
- 7.6.2.3. Regulatory Framework
- 7.6.2.4. Reimbursement Framework
- 7.6.2.5. Japan Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.3. China
- 7.6.3.1. Key Country Dynamics
- 7.6.3.2. Target Disease Prevalence
- 7.6.3.3. Regulatory Framework
- 7.6.3.4. Reimbursement Framework
- 7.6.3.5. China Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.4. India
- 7.6.4.1. Key Country Dynamics
- 7.6.4.2. Target Disease Prevalence
- 7.6.4.3. Regulatory Framework
- 7.6.4.4. Reimbursement Framework
- 7.6.4.5. India Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.5. Australia
- 7.6.5.1. Key Country Dynamics
- 7.6.5.2. Target Disease Prevalence
- 7.6.5.3. Regulatory Framework
- 7.6.5.4. Reimbursement Framework
- 7.6.5.5. Australia Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.6. South Korea
- 7.6.6.1. Key Country Dynamics
- 7.6.6.2. Target Disease Prevalence
- 7.6.6.3. Regulatory Framework
- 7.6.6.4. Reimbursement Framework
- 7.6.6.5. South Korea Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.7. Thailand
- 7.6.7.1. Key Country Dynamics
- 7.6.7.2. Target Disease Prevalence
- 7.6.7.3. Regulatory Framework
- 7.6.7.4. Reimbursement Framework
- 7.6.7.5. Thailand Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.7. Latin America
- 7.7.1. Latin America Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.7.2. Brazil
- 7.7.2.1. Key Country Dynamics
- 7.7.2.2. Target Disease Prevalence
- 7.7.2.3. Regulatory Framework
- 7.7.2.4. Reimbursement Framework
- 7.7.2.5. Japan Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.7.3. Argentina
- 7.7.3.1. Key Country Dynamics
- 7.7.3.2. Target Disease Prevalence
- 7.7.3.3. Regulatory Framework
- 7.7.3.4. Reimbursement Framework
- 7.7.3.5. China Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.8. Middle East and Africa
- 7.8.1. Middle East and Africa Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2017 - 2030 (USD Million)
- 7.8.2. South Africa
- 7.8.2.1. Key Country Dynamics
- 7.8.2.2. Target Disease Prevalence
- 7.8.2.3. Regulatory Framework
- 7.8.2.4. Reimbursement Framework
- 7.8.2.5. South Africa Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.8.3. Saudi Arabia
- 7.8.3.1. Key Country Dynamics
- 7.8.3.2. Target Disease Prevalence
- 7.8.3.3. Regulatory Framework
- 7.8.3.4. Reimbursement Framework
- 7.8.3.5. Saudi Arabia Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.8.4. UAE
- 7.8.4.1. Key Country Dynamics
- 7.8.4.2. Target Disease Prevalence
- 7.8.4.3. Regulatory Framework
- 7.8.4.4. Reimbursement Framework
- 7.8.4.5. UAE Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.8.5. Kuwait
- 7.8.5.1. Key Country Dynamics
- 7.8.5.2. Target Disease Prevalence
- 7.8.5.3. Regulatory Framework
- 7.8.5.4. Reimbursement Framework
- 7.8.5.5. Kuwait Ultomiris (Ravulizumab) Drug Market Estimates and Forecasts, 2018 - 2030 (USD Million)
Chapter 8. Competitive Landscape
- 8.1. Strategy Mapping
- 8.2. Company Profiles/Listing
- 8.2.1. AstraZeneca
- 8.2.1.1. Overview
- 8.2.1.2. Financial Performance
- 8.2.1.3. Product Benchmarking
- 8.2.1.4. Strategic Initiatives