Product Code: GVR-1-68038-473-4
Protein Expression Market Growth & Trends
The global protein expression market size is expected to reach USD 6.64 billion by 2030, according to a new report by Grand View Research, Inc., expanding at a CAGR of 9.36% from 2023 to 2030. The increasing research in proteomics and genomics, the rising incidence of chronic diseases, and escalating demand for biologic products around the globe are enhancing the demand for protein expression, which is likely to drive the market. For instance, in April 2022, in a research published on Frontiers Media S.A., researchers differentially expressed 22 proteins to identify potential diagnostic biomarkers for Multiple Sclerosis (MS).
An increase in R&D investments by the players is estimated to have a considerable impact on the usage of protein expression. In August 2022, the managing director of Biocon Biologics stated in one of his interviews that the overall cost of the R&D is 12-14% of revenues. The investment is essential to build a sustainable portfolio of around 20 biosimilar molecules and the company is anticipated to launch at least once every 1-2 years. The approximate cost of developing these molecules is USD 50-100 million.
Other determinants such as rapid acceleration in the demand for protein therapeutics and government investment in the applications of the protein expression industry are also supporting the market growth. For instance, in May 2022, Proteomics International Laboratories was awarded approximately USD 286,833 funding from the Australian Government under the Medical Research Future Fund (MRFF) initiative. The funding is expected to support the manufacturing of the PromarkerD test in Australia. Such financial assistances are likely to supplement the market growth in the coming years.
The outbreak of the COVID-19 pandemic developed the urge to profile and conduct differential gene expression analyses on COVID-19 patients. Research published in Briefings in Bioinformatics, March 2021, employed the data of protein-drug interaction to identify the prospective drugs for COVID-19. As a result, the usage of the process is projected to upsurge during the COVID-19 pandemic and contribute to market growth.
The growing requirement for personalized therapy and vaccine is expected to be the key factor fueling the market growth during the forecast period. For instance, in January 2022, Amgen announced a collaboration with Generate Biomedicines to discover and develop protein therapeutics for various areas. The companies are estimating the worth of this collaboration around USD 1.9 billion.
The increasing development of recombinant proteins for industrial use, such as the production of food and beverages, is anticipated to boost the use of protein expression in the non-healthcare sector. However, the retail pricings of recombinant proteins for industrial and pharmaceutical uses are drastically different as pharmaceutical proteins are sold for billions of dollars per kg, while industrial proteins for tens of dollars per kg. R&D, clinical trials, and patents are the additional requirements of pharmaceutical proteins.
Protein Expression Market Report Highlights
- By expression system, the prokaryotic segment accounted for the largest share in 2022. The high usage of this system among the researchers is due to enabling them to produce biologically active proteins in large quantities in a short time
- By product, the services segment is anticipated to witness lucrative growth over the forecast period. The increasing outsourcing to CROs and growing demand for recombinant protein in the non-healthcare sectors are fueling the segment growth
- By application, the therapeutic segment dominated the market in 2022. This is attributed to an increase in R&D investment and strategic initiatives such as fundraising
- By end-user, the pharmaceutical and biotechnological companies segment held the largest revenue share in 2022 owing to the growing demand for biologics for chronic diseases
- North America dominated the global market in 2022 owing to the availability of funding opportunities for emerging players, along with the existence of significant R&D investment in the region
Table of Contents
Chapter 1. Methodology and Scope
- 1.1 Market Segmentation and Scope
- 1.1.1 Segment Definitions
- 1.1.1.1 Expression System Segment
- 1.1.1.2 Product Segment
- 1.1.1.3 Application Segment
- 1.1.1.4 End User Segment
- 1.2 Information Procurement
- 1.2.1 Market Formulation & Data Visualization
- 1.2.2 Data Validation & Publishing
- 1.3 Research Assumptions
- 1.4 Research Methodology
- 1.4.1 Purchased Database
- 1.4.2 Gvr's Internal Database
- 1.4.3 Secondary Sources
- 1.4.5 Primary Research
- 1.4.6 Details Of Primary Research
- 1.5 Information Or Data Analysis
- 1.5.1 Data Analysis Models
- 1.6 Market Formulation & Validation
- 1.7 Model Details
- 1.7.1 Commodity Flow Analysis
- 1.7.1.1 Approach 1: Commodity flow approach
- 1.8 List of Secondary Sources
- 1.9 Global Market: CAGR Calculation
- 1.10 Objectives
Chapter 2. Executive Summary
- 2.1. Market Snapshot
- 2.2. Segment Snapshot
- 2.3. Competitive Landscape Snapshot
Chapter 3. Protein Expression Market Variables and Trends
- 3.1. Market Lineage Outlook
- 3.1.1. Parent Market Outlook
- 3.1.2. Related/Ancillary Market Outlook
- 3.2. Market Dynamics
- 3.2.1. Market Driver Impact Analysis
- 3.2.1.1. Escalating Demand For Biologics
- 3.2.1.2. Increasing Investment In R&D
- 3.2.1.3. Rising Funding By Government For Proteomics And Genomics Research
- 3.2.2. Market Restraint Impact Analysis
- 3.2.2.1. Stringent government rules and regulations
- 3.2.2.2. Intense competition among vendors
- 3.3. Industry Analysis Tools
- 3.3.1.1. Porter's Five Forces Analysis
- 3.3.1.2. PESTEL Analysis
- 3.3.1.3. COVID-19 Impact Analysis
Chapter 4. Protein Expression System Business Analysis
- 4.1 Protein Expression Market: Expression Systems Movement Analysis
- 4.2 Prokaryotic Expression Systems
- 4.2.1 Prokaryotic expression systems market, 2018 - 2030 (USD Million)
- 4.3 Mammalian Cell Expression Systems
- 4.3.1 Mammalian cell expression systems market, 2018 - 2030 (USD Million)
- 4.4 Insect Cell Expression Systems
- 4.4.1 Insect cell expression systems market, 2018 - 2030 (USD Million)
- 4.5 Yeast Expression Systems
- 4.5.1 Yeast expression systems market, 2018 - 2030 (USD Million)
- 4.6 Other Expression Systems
- 4.6.1 Other expression systems market, 2018 - 2030 (USD Million)
Chapter 5. Product Business Analysis
- 5.1 Protein Expression Market: Product Movement Analysis
- 5.2 Reagents
- 5.2.1 Reagents market, 2018 - 2030 (USD Million)
- 5.3 Competent Cells
- 5.3.1 Competent cells market, 2018 - 2030 (USD Million)
- 5.4 Expression Vectors
- 5.4.1 Expression vectors market, 2018 - 2030 (USD Million)
- 5.5 Services
- 5.5.1 Services market, 2018 - 2030 (USD Million)
- 5.6 Instruments
- 5.6.1 Instruments market, 2018 - 2030 (USD Million)
Chapter 6. Application Business Analysis
- 6.1 Protein Expression Market: Application Movement Analysis
- 6.2 Therapeutic Applications
- 6.2.1 Therapeutic applications market, 2018 - 2030 (USD Million)
- 6.3 Industrial Applications
- 6.3.1 Industrial applications market, 2018 - 2030 (USD Million)
- 6.4 Research Applications
- 6.4.1 Research applications Market, 2018 - 2030 (USD Million)
Chapter 7. End-use Business Analysis
- 7.1 Protein Expression Market: End-use Movement Analysis
- 7.2 Pharmaceutical and Biotechnological Companies
- 7.2.1 Pharmaceutical and biotechnological companies market, 2018 - 2030 (USD Million)
- 7.3 Academic Research
- 7.3.1 Academic research market, 2018 - 2030 (USD Million)
- 7.4 Contract Research Organizations
- 7.4.1 Contract research organizations market, 2018 - 2030 (USD Million)
Chapter 8. Regional Business Analysis
- 8.1. Protein Expression Market Share By Region, 2022 & 2030
- 8.2. North America
- 8.2.1. North America Protein Expression Market, 2018 - 2030 (USD Million)
- 8.2.2. U.S.
- 8.2.2.1. Key Country Dynamics
- 8.2.2.2. Target Disease Prevalence
- 8.2.2.3. Competitive Scenario
- 8.2.2.4. U.S. Protein Expression Market, 2018 - 2030 (USD Million)
- 8.2.3. Canada
- 8.2.3.1. Key Country Dynamics
- 8.2.3.2. Target Disease Prevalence
- 8.2.3.3. Competitive Scenario
- 8.2.3.4. Canada Protein Expression Market, 2018 - 2030 (USD Million)
- 8.3. Europe
- 8.3.1. Europe Protein Expression Market, 2018 - 2030 (USD Million)
- 8.3.2. UK
- 8.3.2.1. Key Country Dynamics
- 8.3.2.2. Target Disease Prevalence
- 8.3.2.3. Competitive Scenario
- 8.3.2.4. UK Protein Expression Market, 2018 - 2030 (USD Million)
- 8.3.3. Germany
- 8.3.3.1. Key Country Dynamics
- 8.3.3.2. Target Disease Prevalence
- 8.3.3.3. Competitive Scenario
- 8.3.3.4. Germany Protein Expression Market, 2018 - 2030 (USD Million)
- 8.3.4. France
- 8.3.4.1. Key Country Dynamics
- 8.3.4.2. Target Disease Prevalence
- 8.3.4.3. Competitive Scenario
- 8.3.4.4. France Protein Expression Market, 2018 - 2030 (USD Million)
- 8.3.5. Italy
- 8.3.5.1. Key Country Dynamics
- 8.3.5.2. Target Disease Prevalence
- 8.3.5.3. Competitive Scenario
- 8.3.5.4. Italy Protein Expression Market, 2018 - 2030 (USD Million)
- 8.3.6. Spain
- 8.3.6.1. Key Country Dynamics
- 8.3.6.2. Target Disease Prevalence
- 8.3.6.3. Competitive Scenario
- 8.3.6.4. Spain Protein Expression Market, 2018 - 2030 (USD Million)
- 8.3.7. Denmark
- 8.3.7.1. Key Country Dynamics
- 8.3.7.2. Target Disease Prevalence
- 8.3.7.3. Competitive Scenario
- 8.3.7.4. Denmark Protein Expression Market, 2018 - 2030 (USD Million)
- 8.3.8. Sweden
- 8.3.8.1. Key Country Dynamics
- 8.3.8.2. Target Disease Prevalence
- 8.3.8.3. Competitive Scenario
- 8.3.8.4. Sweden Protein Expression Market, 2018 - 2030 (USD Million)
- 8.3.9. Norway
- 8.3.9.1. Key Country Dynamics
- 8.3.9.2. Target Disease Prevalence
- 8.3.9.3. Competitive Scenario
- 8.3.9.4. Norway Protein Expression Market, 2018 - 2030 (USD Million)
- 8.4. Asia Pacific
- 8.4.1. Asia Pacific Protein Expression Market, 2018 - 2030 (USD Million)
- 8.4.2. Japan
- 8.4.2.1. Key Country Dynamics
- 8.4.2.2. Target Disease Prevalence
- 8.4.2.3. Competitive Scenario
- 8.4.2.4. Japan Protein Expression Market, 2018 - 2030 (USD Million)
- 8.4.3. China
- 8.4.3.1. Key Country Dynamics
- 8.4.3.2. Target Disease Prevalence
- 8.4.3.3. Competitive Scenario
- 8.4.3.4. China Protein Expression Market, 2018 - 2030 (USD Million)
- 8.4.4. India
- 8.4.4.1. Key Country Dynamics
- 8.4.4.2. Target Disease Prevalence
- 8.4.4.3. Competitive Scenario
- 8.4.4.4. India Protein Expression Market, 2018 - 2030 (USD Million)
- 8.4.5. Australia
- 8.4.5.1. Key Country Dynamics
- 8.4.5.2. Target Disease Prevalence
- 8.4.5.3. Competitive Scenario
- 8.4.5.4. Australia Protein Expression Market, 2018 - 2030 (USD Million)
- 8.4.6. Thailand
- 8.4.6.1. Key Country Dynamics
- 8.4.6.2. Target Disease Prevalence
- 8.4.6.3. Competitive Scenario
- 8.4.6.4. Thailand Protein Expression Market, 2018 - 2030 (USD Million)
- 8.4.7. South Korea
- 8.4.7.1. Key Country Dynamics
- 8.4.7.2. Target Disease Prevalence
- 8.4.7.3. Competitive Scenario
- 8.4.7.4. South Korea Protein Expression Market, 2018 - 2030 (USD Million)
- 8.5. Latin America
- 8.5.1. Latin America Protein Expression Market, 2018 - 2030 (USD Million)
- 8.5.2. Brazil
- 8.5.2.1. Key Country Dynamics
- 8.5.2.2. Target Disease Prevalence
- 8.5.2.3. Competitive Scenario
- 8.5.2.4. Brazil Protein Expression Market, 2018 - 2030 (USD Million)
- 8.5.3. Mexico
- 8.5.3.1. Key Country Dynamics
- 8.5.3.2. Target Disease Prevalence
- 8.5.3.3. Competitive Scenario
- 8.5.3.4. Mexico Protein Expression Market, 2018 - 2030 (USD Million)
- 8.5.4. Argentina
- 8.5.4.1. Key Country Dynamics
- 8.5.4.2. Target Disease Prevalence
- 8.5.4.3. Competitive Scenario
- 8.5.4.4. Argentina Protein Expression Market, 2018 - 2030 (USD Million)
- 8.6. MEA
- 8.6.1. MEA Protein Expression Market, 2018 - 2030 (USD Million)
- 8.6.2. South Africa
- 8.6.2.1. Key Country Dynamics
- 8.6.2.2. Target Disease Prevalence
- 8.6.2.3. Competitive Scenario
- 8.6.2.4. South Africa Protein Expression Market, 2018 - 2030 (USD Million)
- 8.6.3. Saudi Arabia
- 8.6.3.1. Key Country Dynamics
- 8.6.3.2. Target Disease Prevalence
- 8.6.3.3. Competitive Scenario
- 8.6.3.4. Saudi Arabia Protein Expression Market, 2018 - 2030 (USD Million)
- 8.6.4. UAE
- 8.6.4.1. Key Country Dynamics
- 8.6.4.2. Target Disease Prevalence
- 8.6.4.3. Competitive Scenario
- 8.6.4.4. UAE Protein Expression Market, 2018 - 2030 (USD Million)
- 8.6.5. Kuwait
- 8.6.5.1. Key Country Dynamics
- 8.6.5.2. Target Disease Prevalence
- 8.6.5.3. Competitive Scenario
- 8.6.5.4. Kuwait Protein Expression Market, 2018 - 2030 (USD Million)
Chapter 9. Competitive Landscape
- 9.1. Company Categorization
- 9.2. Strategy Mapping
- 9.3. Company Market Share Analysis, 2022
- 9.4. Company Profiles/Listing
- 9.4.1. Agilent Technologies, Inc
- 9.4.1.1. Overview
- 9.4.1.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.1.3. Product Benchmarking
- 9.4.1.4. Strategic Initiatives
- 9.4.2. QIAGEN
- 9.4.2.1. Overview
- 9.4.2.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.2.3. Product Benchmarking
- 9.4.2.4. Strategic Initiatives
- 9.4.3. Thermo Fisher Scientific, Inc.
- 9.4.3.1. Overview
- 9.4.3.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.3.3. Product Benchmarking
- 9.4.3.4. Strategic Initiatives
- 9.4.4. Merck KGaA
- 9.4.4.1. Overview
- 9.4.4.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.4.3. Product Benchmarking
- 9.4.4.4. Strategic Initiatives
- 9.4.5. Bio-Rad Laboratories, Inc.
- 9.4.5.1. Overview
- 9.4.5.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.5.3. Product Benchmarking
- 9.4.5.4. Strategic Initiatives
- 9.4.6. Promega Corporation
- 9.4.6.1. Overview
- 9.4.6.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.6.3. Product Benchmarking
- 9.4.6.4. Strategic Initiatives
- 9.4.7. New England Biolabs
- 9.4.7.1. Overview
- 9.4.7.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.7.3. Product Benchmarking
- 9.4.7.4. Strategic Initiatives
- 9.4.8. Takara Bio, Inc.
- 9.4.8.1. Overview
- 9.4.8.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.8.3. Product Benchmarking
- 9.4.8.4. Strategic Initiatives
- 9.4.9. Oxford Expression Technologies
- 9.4.9.1. Overview
- 9.4.9.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.9.3. Product Benchmarking
- 9.4.9.4. Strategic Initiatives
- 9.4.10. Lucigen Corporation
- 9.4.10.1. Overview
- 9.4.10.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 9.4.10.3. Product Benchmarking
- 9.4.10.4. Strategic Initiatives