![]() |
市場調査レポート
商品コード
1373370
インフルエンザ治療薬の世界市場-2023年~2030年Global Influenza Therapeutics Market - 2023-2030 |
||||||
カスタマイズ可能
適宜更新あり
|
インフルエンザ治療薬の世界市場-2023年~2030年 |
出版日: 2023年10月18日
発行: DataM Intelligence
ページ情報: 英文 195 Pages
納期: 即日から翌営業日
|
インフルエンザは、悪寒、発熱などの症状を伴う、インフルエンザウイルスによるインフルエンザ様疾患です。ほとんどの人は、すでに感染している患者の咳やくしゃみから空気中に浮遊する小さな飛沫を吸い込むことでインフルエンザに感染します。疾病管理予防センターは、死に至る深刻なリスクを予防するために、毎年インフルエンザの予防接種を受けることを推奨しています。
インフルエンザの流行は毎年発生しており、インフルエンザのような症状がある人の多くは、抗ウイルス薬や抗菌薬などの市販薬を使用しています。世界保健機関(WHO)によると、世界全体のインフルエンザ罹患率は毎年、小児人口の20%から30%、成人人口の約10%です。インフルエンザによる死亡者数は年間約29万~65万人です。
ワクチンの臨床試験は、その安全性、免疫原性、有効性プロファイルを試験しながら進行中です。これらのワクチンは、有効性と安全性を高め、有害な影響を減らすために開発されています。例えば、clinical.govによると、マヒドン大学とGovernment Pharmaceutical Organizationは、季節性3価不活化スプリットビリオンインフルエンザワクチンであるTri Fluvacの免疫原性と安全性を評価する第3相臨床試験を実施しています。開始日は2020年8月3日。終了予定日は2023年12月31日です。
米国国立アレルギー感染症研究所(NIAID)は、健康成人を対象としたモザイク六価インフルエンザワクチンVRC-FLUMOS0116-00-VP(FluMos-v2)の安全性と忍容性を評価する第1相臨床試験を実施しています。開始日は2023年8月9日。完了予定日は2024年12月16日。
南京善信医薬有限公司は、中国の成人合併症のないインフルエンザ患者を対象に、ZX-7101Aを比較する第2相および第3相試験を実施しています。ZX-7101Aの安全性と有効性も評価します。試験開始日は2022年9月17日。終了予定日は2024年6月30日。
インフルエンザ治療薬の副作用は軽度で、吐き気や嘔吐など治療可能なものです。気管支痙攣や下痢を起こす抗ウイルス薬はほとんどありません。バロキサビルのような他の薬剤は、妊婦や授乳中の女性が服用すると重篤な合併症を引き起こすため、経口オセルタミビルは妊婦に推奨されています。根本的なリスクのため、ザナミビルは7歳以上の早期インフルエンザ治療薬として承認されています。
Influenza is a flu-like illness caused by the influenza virus with symptoms such as chills, fever, etc. Most people contract the flu by breathing in tiny airborne droplets from the coughs or sneezes of already infected patients. The Centers for Disease Control and Prevention recommends people get flu shots annually to prevent serious risks that lead to death.
Outbreaks of influenza occur every year, and many people with flu-like symptoms use over-the-counter medication such as anti-viral drugs, anti-microbial drugs, etc. According to the World Health Organization (WHO), the annual global influenza attack rate ranges from 20% to 30% of the child population and around 10% of the adult population. The number of deaths due to influenza is approximately 290,000-650,000 annually.
Clinical trials are ongoing for vaccines, testing their safety, immunogenicity, and efficacy profiles. These vaccines are developed to increase efficacy and safety and decrease the harmful effects. For instance, according to clinical.gov, Mahidol University and the Government Pharmaceutical Organization conduct phase 3 clinical trials to evaluate the immunogenicity and safety of Tri Fluvac, a seasonal trivalent inactivated split virion influenza vaccine. The start date is August 3, 2020. The estimated completion date is December 31, 2023.
The National Institute of Allergy and Infectious Diseases (NIAID) is conducting a phase 1 clinical trial to assess the safety and tolerability of a Mosaic Hexavalent Influenza Vaccine VRC-FLUMOS0116-00-VP (FluMos-v2) in Healthy Adults. The start date is August 9, 2023. The estimated completion date is December 16, 2024.
Nanjing Zenshine Pharmaceuticals conducts phase 2 and 3 trials to compare ZX-7101A in Chinese adult patients with uncomplicated influenza. The safety and efficacy of ZX-7101A is also assessed. The study start date is September 17, 2022. The estimated completion date is June 30, 2024.
Influenza drug side effects are mild and treatable, such as nausea and vomiting. Few anti-viral drugs cause bronchospasm as well as diarrhea. Oral oseltamivir is recommended for pregnant women as other medications like Baloxavir have severe complications when taken by pregnant women or breastfeeding women, as there is no safety data available for this drug. Due to the underlying risks, Zanamivir is approved for early flu treatment in people seven years and older.
The global influenza therapeutics market is segmented based on disease type, therapeutics, route of administration end user and region.
Vaccines are the most effective treatment for influenza compared to drugs, as vaccines give long-term protection to the patient. mRNA vaccines work more precisely and quickly as they destroy the primary target and cure the disease. Vaccine manufacturers like Pfizer and Moderna are working on the launch of mRNA vaccines for influenza.
In September 2022, Pfizer Inc. initiated clinical trial phase 3 to evaluate the efficacy, tolerability, and immunogenicity of quadrivalent modified RNA (modRNA) influenza vaccine.
In February 2023, Moderna initiated a phase 3 clinical trial to assess the safety and efficacy of mRNA-1010, a seasonal influenza vaccine candidate.
North America is expected to hold the largest share in the market owing to the presence of giant vaccine manufacturers such as Pfizer, moderna, etc., and the increasing prevalence of the disease in the US, Canada, etc. Several people from flu belong to the North American region.
Influenza is a contagious disease which affects more that affects nearly 8% of the U.S. population annually. According to the World Health Organization (WHO), Seasonal influenza leads to an estimated 650,000 deaths worldwide yearly. More than 90% of influenza deaths occur in adults at least 65.
According to the Government of Canada's annual report on seasonal influenza, During the 2021-2022 influenza season, 16,126 laboratory-confirmed influenza detections were reported out of 751,900 total laboratory tests. Nearly 71% of seniors (65 and older) are affected by influenza yearly.
COVID-19 has significantly impacted the influenza therapeutics market as there is a shift in the focus on developing vaccines and drugs for the treatment of COVID-19. Lockdowns are implemented worldwide, which halted many processes like supply chain and doctor visits. Diagnosis and treatment of influenza were postponed due to the fear of contracting the infection. As there was an emergency in the COVID-19 vaccine development, the other research activities were stopped by government authorities.
The major global players in the influenza therapeutics market include: Merck KGaA, Santa Cruz Biotechnology, Inc., Biosynth, Teva Pharmaceuticals USA, Inc., Biorbyt Ltd., Thermo Fisher Scientific Inc., Steris, Healthcare PVT Ltd., Genentech, Inc., Lupin Pharmaceuticals, Inc., BioCryst Pharmaceuticals, Inc. among others.
The global influenza therapeutics market report would provide approximately 69 tables, 67 figures, and 195 Pages.