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陰茎がん治療の世界市場-2023年~2030年Global Penile Cancer Treatment Market - 2023-2030 |
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陰茎がん治療の世界市場-2023年~2030年 |
出版日: 2023年09月27日
発行: DataM Intelligence
ページ情報: 英文 195 Pages
納期: 約2営業日
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世界の陰茎がん治療市場は、2022年に23億米ドルに達し、2023-2030年の予測期間中にCAGR 5.6%で成長し、2030年には32億米ドルに達すると予測されています。
陰茎がん治療市場は、陰茎がんの罹患率の増加、治療オプションの進歩、認知度、早期発見、政府の支援策、医療費の増加、個別化医療などの要因によって牽引されています。
より大きな腫瘍学市場のサブセットである陰茎がん治療市場は、この病気と診断された人々に医薬品や医療介入を提供することに重点を置いています。市場には、手術、放射線療法、化学療法、標的薬、免疫療法など、さまざまな種類の治療オプションがあります。
Frontiers in 2022に掲載された論文によると、2020年に予想される陰茎がんの世界発生率は36,068例(10万人あたり0.92例)です。しかし、低開発国では悪性腫瘍の発生率は6.1症例/10万人に達する可能性があります。扁平上皮がん(SCC)は最も一般的な組織型であり、ほぼすべての発生に関与しています。根治手術の場合、リンパ節転移のない早期がんでは10年後の全生存率(OS)は96%であるのに対し、局所リンパ節転移や遠隔転移のある患者では5年後の全生存率はそれぞれ50%と12%です。
典型的な化学療法毒性と緩やかな生存成績により、進行病変の治療においてもネオアジュバント療法においても、細胞毒性化学療法は全身治療において重要な役割を果たしています。これは主にプラチナ製剤とタキサン系薬剤の併用レジメンで構成されています。
2022年にNature Reviews Urology誌に掲載された論文によると、国を超えて治療と治療を標準化し、陰茎がんなどのまれな泌尿生殖器がんにまつわる重大な臨床的ギャップを明らかにし、これらの患者の余命を延ばすためには、国際的な協力が緊急に必要です。世界稀少泌尿生殖器腫瘍学会(GSRGT)は、このような目的を達成することを目指しています。GSRGTの最初の目標は、まれな腫瘍の重要な発生源でありながら、以前は登録や研究から除外されていた発展途上国を取り込むことです。
例えば、南米、アフリカ、インド、アジアの3次医療施設は、世界各地からの迅速かつ徹底したデータ回収を可能にするために、北米および欧州の学術センターと協力しています。エビデンスに基づいた最善の治療を患者に提供するため、GSRGTは、陰茎がんに関する最新かつアクセスしやすい情報を広めるべく、各国の医師間の協力を促していく。これは、評判の高い医学会と協力することで達成されます。
化学療法薬は急速に分裂する細胞を標的とするため、がん細胞に対して有効です。しかし、骨髄(新しい血液細胞が産生される場所)、口や腸の粘膜、毛根など、体内の一部の細胞は分裂が早いです。これらの細胞は化学療法によって影響を受ける可能性があり、好ましくない影響が出ることがあります。
化学療法薬の種類、投与量、投与期間は、副作用に影響します。典型的な悪影響としては、脱毛、口内炎、食欲減退、嘔吐、吐き気、便秘または下痢、感染症のリスク増加(白血球の減少のため)、血小板数の低下によるあざや出血のしやすさ、疲労などがあります。
加えて、発がんや腫瘍の進行に関与する分子生物学やゲノム・エピゲノムの変化が十分に理解されていないことや、前向き臨床試験に患者を登録することが困難であることが、陰茎がんのような稀な腫瘍の治療の進歩を常に妨げてきました。
The Global Penile Cancer Treatment Market reached US$ 2.3 billion in 2022 and is expected to reach US$ 3.2 billion by 2030 growing with a CAGR of 5.6% during the forecast period 2023-2030.
The penile cancer treatment market is driven by factors such as increasing incidence of penile cancer, advancements in treatment options, awareness, and early detection, supportive government initiatives, increasing healthcare expenditure, and personalized medicine.
A subset of the larger oncology market, the penile cancer treatment market focuses on offering medicines and medical interventions to people who have been diagnosed with the disease. There are many different types of treatment options available on the market, including surgery, radiation therapy, chemotherapy, targeted medicines, and immunotherapy.
As per the article published in Frontiers in 2022, the anticipated global incidence of penile cancer in 2020 is 36,068 cases (0.92 incidences per 100,000 individuals). However, the incidence of malignant tumors might be up to 6.1 cases/100,000 people in underdeveloped nations. Squamous cell carcinoma (SCC) is the most common histology and is responsible for almost all occurrences. With curative surgery, overall survival (OS) in individuals with early disease without nodal involvement is 96% in 10 years, compared to 50% and 12%, respectively, in 5 years for patients with regional node disease and distant metastatic disease.
With typical chemotherapeutic toxicities and modest survival outcomes, both in the treatment of advanced disease and in the neoadjuvant setting, cytotoxic chemotherapy plays a significant role in systemic treatment. It primarily consists of platinum and taxane combination regimens.
As per the article published in Nature Reviews Urology in 2022, in order to standardize care and therapies across nations, uncover the critical clinical gaps around uncommon genitourinary cancers, such as penile cancer, and increase the life expectancy of these patients, international cooperation is urgently required. Global Society of Rare Genito-urinary Tumors (GSRGT) seeks to achieve these objectives. The initial goal of the GSRGT is to incorporate developing nations, which are a significant source of uncommon tumors but were previously excluded from registries and studies.
For instance, tertiary care facilities in South America, Africa, India, and Asia collaborate with academic centers in Europe and North America to enable rapid and thorough data recovery from all corners of the world. In order to provide patients with the best available evidence-based treatments, GSRGT will encourage cooperation between doctors from various nations in order to spread up-to-date and easily accessible information about penile cancer. This will be accomplished through working with reputable medical societies.
Chemotherapy medications target rapidly dividing cells, which is why they are effective against cancer cells. However, some cells in the body divide quickly, including those in the bone marrow (where new blood cells are produced), the lining of the mouth and intestines, and the hair follicles. These cells can be impacted by chemotherapy, which may have unfavorable repercussions.
The type, dosage, and duration of the chemotherapy medications affect the adverse effects. Typical negative consequences include loss of hair mouth ulcers decrease in appetite, vomiting, nauseous, constipation or diarrhea, infection risk is increased (because of decreased white blood cell levels), and low blood platelet counts can cause easy bruising or bleeding as well as fatigue.
In addition, the lack of a thorough understanding of the molecular biology and genomic and epigenomic alterations involved in carcinogenesis and tumor progression, as well as the difficulty in enrolling patients for prospective clinical trials, have always hampered advances in the treatment of rare tumors like penile cancer.
The global penile cancer treatment market is segmented based on type, treatment, end-user and region.
The chemotherapy segment accounted for the highest market stake accounting for approximately 37.6% of the penile cancer treatment market in 2022. Cancer-curing medications are administered orally or by venous injections during systemic chemotherapy. These medications reach cancer cells all around the body via the bloodstream. Penile tumors that have migrated to distant organs or lymph nodes are the most common candidates for this treatment. Before surgery, tumors may be shrunk with chemotherapy to make them easier to remove.
Chemotherapy is administered by doctors in cycles, with a rest interval following each cycle to allow the body to heal. Chemotherapy cycles typically last 3 to 4 weeks. Cisplatin, Fluorouracil (5-FU), Paclitaxel (Taxol), Ifosfamide (Ifex), Mitomycin C, and Capecitabine (Xeloda) are a few of the medications used to treat penile cancer. In order to treat penile cancer that has progressed to lymph nodes or other organs, 2 or more of these medications are frequently combined. Cisplatin plus 5-FU is one of the most often used combos.
North America is estimated to hold around 1/3rd of the total market share throughout the forecast period. The active major players are driving the market in the North American region. Penile cancer is a rare form of cancer, especially in developed countries. Over 2000 new cases are reported annually in the United States, with rates of fewer than 1 per 100,000 men. However, there is a much higher occurrence in underdeveloped countries, where there is also a lack of therapeutic knowledge and access to care, which contributes to an unmet clinical need. The link with human papillomavirus infection, which may be present in as many as 50% of all penile carcinomas, is the most notable risk factor for penile cancer.
Older men are more likely to get penile cancer, and the incidence rate continually rises with age. Penile cancer most frequently affects men between the ages of 50 and 70, with a mean age of 67 in the United States of America.
The major global players in the market include: Merck, GlaxoSmithKline, Pfizer, Bristol-Myers Squibb, Roche, Novartis, Shanghai Junshi Biosciences Co., Ltd., Innovent Biologics, Jiangsu Hengrui Medicine Co., Ltd., and BeiGene Ltd. among others.
The Russia-Ukraine war may affect the penile cancer treatment market due to a lack of facilities being impacted during times of geopolitical instability and economic uncertainty. Healthcare workers are frequently displaced, medical supply lines are disrupted, and healthcare facilities are damaged during armed conflicts. The impacted people in Russia and Ukraine have less access to cancer detection and treatment options as a result.
Artificial intelligence (AI) is increasingly being used in the penile cancer treatment market to improve various aspects of data analysis. AI can help oncologists create individualised treatment plans for patients with penile cancer. AI can make therapeutic recommendations that are specific to each patient by examining patient data, medical history, and the results of similar instances.
The global penile cancer treatment market report would provide approximately 69 tables, 71 figures, and 195 Pages.
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